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Unraveling brain aging through the lens of oral microbiota

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Neural Regeneration Research 2025年第7期20卷 1930-1943页

作者： Qinchao Hu Si Wang Weiqi Zhang Jing Qu Guang-Hui Liu State Key Laboratory of Membrane Biology Institute of ZoologyChinese Academy of SciencesBeijingChina Hospital of Stomatology Guanghua School of StomatologyGuangdong Provincial Key Laboratory of StomatologySun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Advanced Innovation center for Human Brain Protection and National Clinical Research center for Geriatric Disorders Xuanwu HospitalCapital Medical UniversityBeijingChina Aging Translational Medicine center International Center for Aging and CancerBeijing Municipal Geriatric Medical Research CenterXuanwu HospitalCapital Medical UniversityBeijingChina CAS Key Laboratory of Genomic and Precision Medicine Beijing Institute of GenomicsChinese Academy of Sciences and China National Center for BioinformationBeijingChina University of Chinese Academy of Sciences BeijingChina Institute for Stem Cell and Regeneration Chinese Academy of SciencesBeijingChina Aging Biomarker Consortium BeijingChina State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijingChina Beijing Institute for Stem Cell and Regenerative Medicine BeijingChina

The oral cavity is a complex physiological community encompassing a wide range of *** of oral microbiota can lead to various oral infectious diseases,such as periodontitis and tooth decay,and even affect systemic health,including brain aging and neurodegenerative *** studies have highlighted how oral microbes might be involved in brain aging and neurodegeneration,indicating potential avenues for intervention *** this review,we summarize clinical evidence demonstrating a link between oral microbes/oral infectious diseases and brain aging/neurodegenerative diseases,and dissect potential mechanisms by which oral microbes contribute to brain aging and *** also highlight advances in therapeutic development grounded in the realm of oral microbes,with the goal of advancing brain health and promoting healthy aging.

关键词： Alzheimer's disease brain aging multiple sclerosis neurodegeneration neurodegenerative diseases oral microbiota Parkinson's disease periodontitis bacteria Porphyromonas gingivalis

Up-conversion of Er^(3+)/Yb^(3+)co-doped transparent glass-ceramics containing Ba_2LaF_7 nanocrystals

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Journal of Rare Earths 2013年第9期31卷 843-848页

作者：胡金民周大成王荣飞陈明厚焦清余雪邱建备 School of Materials Science and Engineering Kunming University of Science and Technology Department of Research Admini stration and international relations Tuyhoa Industrial College

The up-conversion of Er3＋/yb3＋ co-doped transparent glass-ceramics 50SiO2-10A1F3-5TiO2-30BaF2-4LaF3-0.5ErF3-0.5YbF3 containing Ba2LaF7 nanocrystals under the changing of heat treatment temperature and time were investigated. The Ba2LaF7 nanocrystals precipitated from the glass matrix was confirmed by X-ray diffraction （XRD）. The structural investigation carried out by XRD and trans- mission electron microscopy （TEM） evidenced the formation of cubic Ba2LaF7 nanocrystals with crystal size of about 14 nm. Comparing with the samples before heat treatment, the high efficiency up-conversion emission of Er3＋/Yb3＋ co-doped samples was observed in the glass-ceramics under 980 nm laser diode excitation. The increase in red emission intensity bands was stronger than the green bands when the crystal size increased. The mechanism for the up-conversion process in the glass-ceramics and the reasons for the increase of Er3＋/yb3＋ co-doped up-conversion intensity after heat treatment were discussed.

关键词： up-conversion BazLaF7 nanocrystals glass-ceramics rare earths

Great Power Struggles

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Contemporary international relations 2014年第4期24卷 11-16页

作者： Zhao Xiaochun Zhao Jinfu the center for international Strategic and Security Studies at the University of international relations

international order is the norm,standards and corresponding guaranteeing mechanism,decision-making process,and rule of procedures established by members of the international system to coordinate and deal with various international affairs,in order to maintain stability and the normal operation of the international *** an international public product,international order is usually supplied by the major actors of

关键词：国际秩序决策过程正常运行公共产品提供者

Constructing Pr-doped CoOOH catalytic sites for efficient electrooxidation of 5-hydroxymethylfurfural

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Journal of Energy Chemistry 2025年第1期 234-244页

作者： Botao Fan Hao Zhang Bang Gu Feng Qiu Qiue Cao Wenhao Fang School of Chemical Science and Technology Yunnan University National center for international Research on Photoelectric and Energy Materials School of Materials and Energy Yunnan University

Electrocatalytic conversion of renewable biomass is emerging as a promising route for sustainable chemical production;hence it urgently calls for developing efficient electrocatalysts with low potentials and high current ***,a Pr-doped Co（OH）2hexagonal sheet （Pr/Co=1/9,in mole） is synthesized by electrodeposition as highly performant catalyst for 5-hydroxymethylfurfural （HMF） oxidation reaction（HMFOR） to produce 2,5-furandicarboxylic acid （FDCA）.This novel and low-cost catalyst possesses a rather low onset potential of 1.05 V （***） and requires only 1.10 V （***） to reach a current density of 10 mA cm-2for HMFOR,significantly outperforming Co（OH）2benchmark (i.e.,210 mV higher to reach10 m A cm-2).The origin of Pr promotion effect as well as the evolution of CoOOH catalytic sites and HMFOR process has been deeply elucidated by physical characterizations,kinetic experiments,in situ electrochemical techniques,and theoretical *** unique Pr-ameliorated CoOOH active centers enable 100%conversion of HMF,99.6%selectivity of FDCA,and 99.7%Faraday efficiency,with a superior cycling durability toward *** can be one of the most outstanding results for Co-based HMFOR catalysts to date in the *** this work can help open up new horizons for constructing novel and efficient Co-based electrocatalysts by the utilization of lanthanide elements.

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China as a Responsible Power Amid the COVID-19 Crisis:Perceptions of Partners and Adversaries on Twitter

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Fudan Journal of the Humanities and Social Sciences 2022年第2期15卷 159-188页

作者： Maria Papageorgiou Daniella da Silva Nogueira de Melo Department of Political Science and international relations University of MinhoBragaPortugal

The challenging COVID-19 context has questioned China’s role as a responsible power but also tested its relationship with other *** study seeks to investigate‘How other actors have perceived China’s role as a responsible power amid the COVID-19 crisis’.To do so,we opt for a qualitative approach examining the official Twitter accounts of seven actors that hold different types of relationships with China,namely Brazil,EU,Japan,Iran,Pakistan,Russia,and the *** aim to identify the perceptions of these actors towards China as unfolding from January to June 2020,emphasising the empirical applicability of Twitter’s *** adopting the concept of responsible power approached from a Role Theory perspective,this paper contributes to a more nuanced understanding of interstate relations and role *** findings indicate that there have been variations in the responses and perceptions other states have expressed towards China while its framing as a responsible power differs significantly during the crisis and its landmark events.

关键词： China COVID-19 Twitter Role theory Responsible power

Unequal error protection scheme for layered sources transmission over MIMO systems using spatial diversity and multiplexing technology

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The Journal of China Universities of Posts and Telecommunications 2015年第3期22卷 56-63页

作者： Zhang Yongjian Zhang Kexin Kang Yanmei Yang Dacheng School of Telecommunication Engineering Beijing University of Posts and Telecommunications University of international relations Academic office Beijing University of Posts and Telecommunications

This paper proposes a hybrid scheme of the Alamouti coding and vertical bell labs layered space-time （V-BLAST） with the zero-forcing （ZF） receiver, which can achieve the unequal error protection （UEP） transmission in terms of the differences of importance in the layered sources. We analyze the tradeoff between spatial diversity and multiplexing in a mathematical manner, and prove the monotonic behavior of the crosspoint. Based on this scheme, we adopt V-BLAST to provide high data rates for the enhancement layer （EL） bitstreams, and adopt Alamouti coding to guarantee high reliability for the base layer （BL） bitstreams. Meanwhile, to improve the transmission reliability for the layered sources under the multiple-input multiple-output （MIMO） system with the limited-bandwidth and the total limited power, and to raise the frequency bandwidth efficiency, we take the power allocation considered in this proposed scheme. The simulation results show that the hybrid scheme has the average 1.9 dB and 1.3 dB gain in video peak signal-to-noise ratio （PSNR）, compared with the pure spatial diversity and pure spatial multiplexing scheme, respectively.

关键词： unequal error protection spatial diversity and multiplexing outage probability multiple-input multiple-output (MIMO) powerallocation

North Korea＇s Fourth Nuclear Test and Changes in Northeast Asia

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Contemporary international relations 2016年第3期26卷 93-114页

作者： Lin Limin Zheng Yu the Foreign Policy Research center of the China Institutes of Contemporary international relations the China Institutes of Contemporary international relations

After North Korea's fourth nuclear test, the Northeast Asian political environment is about to change in several ways. Although efforts by the US, South Korea and Japan to tighten their alliance and provoke a "regime change" in Pyongyang have not restored the former political Cold War climate, the situation on the Korean Peninsula and in Northeast Asia will inevitably grow more complex, confusing and tense because of this move.

关键词：朝鲜半岛东北亚核试验四次政治环境

Qi,Return to Bodily Experience:A New Perspective of Qi and Qigong Experience Research

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Chinese Medicine and Culture 2020年第4期3卷 216-219页

作者： Xinzhe Huang Graduate School of international relations Ritsumeikan UniversityKyotoJapan

For a long period,Qi and Qigong experience were studied within the theoretical framework of natural science,psychology,and *** article reviews the modes and problems of Qi and Qigong researches,discusses the theoretical basis of phenomenological researches in anthropology,exemplifies some important researches and ideas about bodily ***,the possibility and difficulty of utilizing these methodologies and ideas are analyzed out as *** to open up a brand-new horizon of Qi and Qigong research,enriches our understandings of the culture of Qi and Qigong,and makes Qigong better adapt itself to the contemporary and the world.

关键词： Body embodiment phenomenology Qi Qigong experience

A Bibliometric Analysis of Wicked Problems: From Single Discipline to Transdisciplinarity

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Fudan Journal of the Humanities and Social Sciences 2022年第3期15卷 299-329页

作者： Xiaojing Hou Ruichang Li Zhiping Song School of international relations and Public Afairs Fudan UniversityShanghaiChina

With the increase of social complexity and uncertainty,wicked problems have become the hot and difcult issues in the frontier research of public *** concept of wicked problems was proposed in the *** then,it has gradually spread to many disciplines,such as environment,urban planning,public policy,etc.A comprehensive understanding of the research progress of the transdisciplinary method is an important way to understand wicked *** paper uses Citespace5.5,based on bibliometrics and visual analysis techniques,to analyze 800 academic publications related to wicked problems and visually display the transdisciplinarity knowledge map and information panorama of wicked *** a multi-level descriptive analysis of key literature,research origin,research hotspots and trend of the research on wicked problems,this paper fnds out the law of knowledge growth and internal evolution logic of the research on wicked problems,and concludes that the transdisciplinarity research of wicked problems is forming,which shows the rule from knowledge difusion(single discipline)to knowledge coherence(transdisciplinarity).The discipline of public policy has the potential to change the knowledge constraints of a single discipline and may ofer transdisciplinarity approaches to wicked problems.

关键词： Wicked problems Knowledge map Transdisciplinarity research Bibliometric analysis