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Drosophila X virus-like particles as delivery carriers for improved oral insecticidal efficacy of scorpion Androctonus australis peptide against the invasive fruit fly,Drosophila suzukii

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Insect Science 2024年第3期31卷 847-858页

作者： Qi Xue Luc Swevers Clauvis Nji Tizi Taning Faculty of Bioscience Engineering Department of Plants and CropsGhent UniversityGhentBelgium Insect Molecular Genetics and Biotechnology Institute of Biosciences and ApplicationsNational Centre for Scientific Research"Demokritos"AthensGreece

Insect-specific neurotoxic peptides derived from the venoms of scorpions and spiders can cause acute paralysis and death when injected into insects,offering a promising insecticidal component for insect pest ***,effective delivery systems are required to help neurotoxic peptides pass through the gut barrier into the hemolymph,where they can ***,we investigated the potential of a novel nanocarrier,Drosophila X virus-like particle(DXV-VLP),for delivering a neurotoxin from the scorpion Androctonus australis Hector(AaIT)against the invasive pest fruit fly,Drosophila *** results show that the fusion proteins of DXV polyproteins with AalT peptide at their Ctermini could be sufficiently produced in Lepidoptera Hi5 cells in a soluble form using the recombinant baculovirus expression system,and could self-assemble into VLPs with similar particle morphology and size to authentic DXV *** addition,the AalT peptides displayed on DXV-VLPs retained their toxicity,as demonstrated in injection bioassays that resulted in severe mortality(72%)in adults after 72 *** fed to adults,mild mortality was observed in the group treated with DXV-AalT(38%),while no mortality occurred in the group treated with AaIT peptide,thus indicating the significant role of DXV-VLPs in delivering AalT ***,this proof-of-concept study demonstrates for the first time that VLPs can be exploited to enhance oral delivery of insect-specific neurotoxic peptides in the context of pest ***,it provides insights for further improvements and potentially the development of neurotoxin-based bioinsecticides and/or transgenic crops for insect pest control.

关键词： AalT Drosophila suzuki nanocarrier neurotoxic peptides pest control virus-like particle(VLP)

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Target acquisition performance in the presence of JPEG image compression

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Defence Technology（防务技术） 2024年第3期33卷 30-41页

作者： Boban Bondzulic Nenad Stojanovic Vladimir Lukin Sergey A.Stankevich Dimitrije Bujakovic Sergii Kryvenko University of Defence in Belgrade Military AcademyVeljka Lukica Kurjaka 3311000 BelgradeSerbia national Aerospace University Department of Information-Communication TechnologiesChkalova 1761070 KharkivUkraine national Academy of Sciences of Ukraine Scientific Centre for Aerospace Research of the EarthOles Honchar 55-b01054 KyivUkraine

This paper presents an investigation on the effect of JPEG compression on the similarity between the target image and the background,where the similarity is further used to determine the degree of clutter in the *** new clutter metrics based on image quality assessment are introduced,among which the Haar wavelet-based perceptual similarity index,known as HaarPSI,provides the best target acquisition prediction *** is shown that the similarity between the target and the background at the boundary between visually lossless and visually lossy compression does not change significantly compared to the case when an uncompressed image is *** future work,through subjective tests,it is necessary to check whether this presence of compression at the threshold of just noticeable differences will affect the human target acquisition *** values are compared with the results of subjective tests of the well-known target Search_2 database,where the degree of agreement between objective and subjective scores,measured through linear correlation,reached a value of 90%.

关键词： JPEG compression Target acquisition performance Image quality assessment Just noticeable difference Probability of target detection Target mean searching time

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Performance validation of High Mountain Asia 8-meter Digital Elevation Model using ICESat-2 geolocated photons

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Journal of Mountain Science 2024年第8期21卷 2562-2578页

作者： Giribabu DANDABATHULA Subham ROY Omkar Shashikant GHATAGE Vaibhav Balaso KOLASE Shwetambari SATPUTE Koushik GHOSH Sahibnoor KAUR Satyanarayana PONDARI Apurba Kumar BERA Sushil Kumar SRIVASTAV Regional Remote Sensing centre-West National Remote Sensing CentreIndian Space Research OrganisationJodhpur 342005India Department of Geography School of Earth SciencesBharathidasan UniversityTiruchirappalli 620024India centre for Climate Change and Water research Suresh Gyan Vihar UniversityJaipur 302017India Department of Geography Panjab UniversityChandigarh 160014India national Remote Sensing centre Indian Space Research OrganisationHyderabad 500037India Regional centres National Remote Sensing CentreIndian Space Research OrganisationNew Delhi 110049India

High Mountain Asia(HMA),recognized as a third pole,needs regular and intense studies as it is susceptible to climate *** accurate and high-resolution Digital Elevation Model(DEM)for this region enables us to analyze it in a 3D environment and understand its intricate role as the Water Tower of *** science teams of NASA realized an 8-m DEM using satellite stereo imagery for HMA,termed HMA 8-m *** this research,we assessed the vertical accuracy of HMA 8-m DEM using reference elevations from ICESat-2 geolocated photons at three test sites of varied topography and land *** were made from statistical quantifiers and elevation *** the world’s highest mountain,Mount Everest,and its surroundings,Root Mean Squared Error(RMSE)and Mean Absolute Error(MAE)resulted in 1.94 m and 1.66 m,respectively;however,a uniform positive bias observed in the elevation profiles indicates the seasonal snow cover change will dent the accurate estimation of the elevation in this sort of test *** second test site containing gentle slopes with forest patches has exhibited the Digital Surface Model(DSM)features with RMSE and MAE of 0.58 m and 0.52 m,*** third test site,situated in the Zanda County of the Qinghai-Tibet,is a relatively flat terrain bed,mostly bare earth with sudden river cuts,and has minimal errors with RMSE and MAE of 0.32 m and 0.29 m,respectively,and with a negligible ***,in one more test site,the feasibility of detecting the glacial lakes was tested,which resulted in exhibiting a flat surface over the surface of the lakes,indicating the potential of HMA 8-m DEM for deriving the hydrological *** results accrued in this investigation confirm that the HMA 8-m DEM has the best vertical accuracy and should be of high use for analyzing natural hazards and monitoring glacier surfaces.

关键词： High Mountain Asia Digital Elevation Model ICESat-2 geolocated photons Accuracy assessment

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Cobalt-nitrogen co-doped porous carbon sphere as highly efficient catalyst for liquid-phase cyclohexane oxidation with molecular oxygen and the active sites investigation

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Frontiers of Chemical Science and Engineering 2024年第3期18卷 101-112页

作者： Lei Chen Yuan Sun Jinshan Chi Wei Xiong Pingle Liu Fang Hao College of Chemical Engineering National&Local United Engineering Research Centre for Chemical Process Simulation and IntensificationXiangtan UniversityXiangtan411105China

The selective oxidation of cyclohexane to cyclohexanone and cyclohexanol(KA oil)is a challenging issue in the chemical *** present the industrial conversion of cyclohexane to cyclohexanone and cyclohexanol is normally controlled at less than 5%***,the development of highly active and stable catalysts for the aerobic oxidation of cyclohexane is necessary to overcome this low-efficiency ***,we have developed a cobalt-nitrogen co-doped porous sphere catalyst,Co-NC-x(x is the Zn/Co molar ratio,where x=0,0.5,1,2,and 4)by pyrolyzing resorcinol-formaldehyde resin *** achieved 88.28%cyclohexanone and cyclohexanol selectivity and a cyclohexane conversion of 8.88%under *** results showed that the introduction of zinc effectively alleviated the aggregation of Co nanoparticles and optimized the structural properties of the *** addition,Co0 and pyridinic-N are proposed to be the possible active species,and their proportion efficiently increased in the presence of Zn^(2+)*** this study,we developed a novel strategy to design highly active catalysts for cyclohexane oxidation.

关键词： KA oil production cyclohexane selective oxidation cobalt-nitrogen co-doped porous carbon spheres metal-organic framework

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A Comprehensive Analysis of the Thermo-Chemical Properties of Sudanese Biomass for Sustainable Applications

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Journal of Renewable Materials 2024年第4期12卷 721-736页

作者： Wadah Mohammed Zeinab Osman Salah Elarabi Bertrand Charrier Institute of Analytical Sciences and Physical-Chemistry for the Environment and Materials-Xylomat University of Pau and the Adour RegionE2S UPPACNRSIPREM-UMR 5254Mont de Marsan40004France Institute of Engineering research and Materials Technology(IERMT) National Center for Research(NCR)Ministry of Higher Education and Scientific ResearchKhartoum11111Sudan Faculty of Industries Engineering and Technology University of GeziraGezira State21111Sudan

The chemical composition and thermal properties of natural fibers are the most critical variables that determine the overall properties of the fibers and influence their processing and use in different sustainable applications,such as their conversion into bioenergy and *** thermal and mechanical properties can be estimated by evaluating the content of cellulose,lignin,and other extractives in the *** this research work,the chemical composition and thermal properties of three fibers,namely bagasse,kenaf bast fibers,and cotton stalks,were evaluated to assess their potential utilization in producing biocomposites and bioenergy *** chemical composition analysis followed the Technical Association of the Pulp and Paper Industry Standards(TAPPI)*** total phenol content was quantified using the Folin-Ciocalteu method,while Fourier Transform Infrared Spectroscopy(FTIR)was employed to assess the light absorption by the *** evaluate thermal stability and higher heating values,Thermogravimetric Analysis(TGA),Differential Scanning Calorimetry(DSC),and bomb calorimetry were *** chemical analysis revealed that bagasse contained 50.6%cellulose and 21.6%lignin,kenaf bast fibers had 58.5%cellulose and 10%lignin,and cotton stalks exhibited 40.3%cellulose and 21.3%*** FTIR curves demonstrated a notable similarity among the *** TGA analysis showed degradation temperatures of 321°C for bagasse,354°C for kenaf bast fibers,and 289°C for cotton *** DSC analysis revealed glass transition temperatures of 81°C for bagasse,66.3°C for cotton stalks,and 64.5°C for kenaf bast *** higher heating values were measured as 17.3,16.6 and 17.1 MJ/kg for bagasse,kenaf bast fibers,and cotton stalks,*** three fibers have a high potential for biocomposites and bioenergy material manufacturing.

关键词： Bagasse kenaf bast fibers cotton stalks TGA DSC FTIR

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Multi-omics analyses of G6PD deficiency variants in Chinese population

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Journal of Genetics and Genomics 2024年第1期51卷 100-104页

作者： He Ji Jiahuan Chen Peide Huang Zhimin Feng Weining Hu Mengyao Dai Xiaohui Sun Xiao Jin Guangquan Chen Guang Ning Lin Li Weiqing Wang Yanan Cao Department of Endocrine and Metabolic Diseases Shanghai Institute of Endocrine and Metabolic DiseasesNational Clinical Research Centre for Metabolic DiseasesState Key Laboratory of Medical GenomicsResearch Unit of Clinical and Basic Research on Metabolic Diseases of Chinese Academy of Medical SciencesRuijin Yangtze River Delta Health InstituteWuxi Branch of Ruijin HospitalRuijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China national research Center for Translational Medicine National Key Scientific Infrastructure for Translational MedicineShanghai Jiao Tong UniversityShanghai 200240China SJTU-BGI Innovation research Center Shanghai 200240China BGI-ShenZhen ShenzhenGuangdong 518083China

Glucose-6-phosphate dehydrogenase(G6PD)deficiency is one of the most prevalent hereditary and X-linked enzyme disorders caused by the pathogenetic G6PD(NM_001042351.2)variants(Yang et al.,2016).The clinical manifestations of G6PD deficiency offer a wide spectrum of diverse disease phenotypes(Hecker et al.,2013).Investigations of prevalence and molecular epidemiology demonstrate that G6PD deficiency affects over 400 milion individuals worldwide and leads to thousands of deaths annually(Mortality and Causes of Death,2015).

关键词： al. G6PD epidemiology

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Dynamic imaging through scattering medium under white-light illumination [Invited]

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Chinese Optics Letters 2024年第6期22卷 46-51页

作者： Junyao Lei Hui Chen Yuan Yuan Yunong Sun Jianbin Liu Huaibin Zheng Yuchen He Electronic Material research Laboratory Key Laboratory of the Ministry of Education and International Centre for Dielectric ResearchXi’an Jiaotong UniversityXi’an 710049China

Imaging objects hidden behind turbid media is of great scientific importance and practical value, which has been drawing a lot of attention recently. However, most of the scattering imaging methods rely on a narrow linewidth of light, limiting their application. A mixture of the scattering light from various spectra blurs the detected speckle pattern, bringing difficulty in phase retrieval. Image reconstruction becomes much worse for dynamic objects due to short exposure times. We here investigate non-invasively recovering images of dynamic objects under white-light irradiation with the multi-frame OTF retrieval engine (MORE). By exploiting redundant information from multiple measurements, MORE recovers the phases of the optical-transfer-function (OTF) instead of recovering a single image of an object. Furthermore, we introduce the number of non-zero pixels (NNP) into MORE, which brings improvement on recovered images. An experimental proof is performed for dynamic objects at a frame rate of 20 Hz under white-light irradiation of more than 300 nm bandwidth.

关键词： scattering imaging white light illumination phase retrieval algorithm

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Ba^(2+)/Ca^(2+)co-crosslinked alginate hydrogel filtration membrane with high strength,high flux and stability for dye/salt separation

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Chinese Chemical Letters 2024年第5期35卷 320-324页

作者： Ningning Gao Yue Zhang Zhenhao Yang Lijing Xu Kongyin Zhao Qingping Xin Junkui Gao Junjun Shi Jin Zhong Huiguo Wang SINOPEC research Institute of Petroleum Processing CO. LTD.Beijing 100083China State Key Laboratory of Separation Membranes and Membrane Processes/national centre for International Joint research on Separation Membranes Tiangong UniversityTianjin 300387China

Alginate is a natural polysaccharide *** filtration membranes prepared from alginate show excellent fouling resistance and controllable separation performance,but poor mechanical properties limit the use of algae *** this study,Ba^(2+)/Ca^(2+)co-crosslinked alginate(Ba/CaAlg)hydrogel membrane was prepared by cross-linking sodium alginate with a blend aqueous solution of barium ions and calcium ions,and the membrane was applied to the separation of dyes/salts from dyeing *** with the CaAlg membrane,the Ba/CaAlg hydrogel membrane exhibited more stable structure,and the mechanical properties and salt tolerance of the membrane were significantly *** flux of Ba/CaAlg membrane for methyl blue/sodium chloride mixed solution reached 43.5 L m^(−2) h^(−1),which was significantly higher than that of CaAlg ***,the Ba/CaAlg membrane showed higher dye rejection(>99.6%)and lower salt rejection(<8.2%).The structure of Ba/CaAlg membrane was preliminarily simulated by molecular dynamics,and the pore size and distribution of the membrane were *** Ba/CaAlg membrane has a broad application prospect in dyes/salts separation.

关键词： Alginate Filtration membrane Ba^(2+)/Ca^(2+)ion crosslinking Dye/salt separation Molecular dynamic simulation Hydrogel

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Mesenchymal stem cells in wound healing:A bibliometric analysis as a powerful research tool

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World Journal of Stem Cells 2024年第9期16卷 827-831页

作者： Vera V Voinova Daria V Vasina Anton P Bonartsev Faculty of Biology MV Lomonosov Moscow State UniversityMoscow 119234Russia NF Gamaleya national research centre for Epidemiology and Microbiology Ministry of Health of the Russian FederationMoscow 123098Russia

Bibliographic analysis is still very rarely used in experimental basic study *** comprehensive bibliometric analysis of scientific literature on research progress and challenges in stem cell therapy for diabetic chronic wounds,which was conducted in the work of Shi et al can be a case study and a source of valuable information for writing reviews and experimental papers in this *** experimental studies on a role of mesenchymal stem cells(MSCs)in wound healing that are published in 2023-2024,such as Zhang et al in 2023,Hu et al in 2023,Wang et al in 2023 are certainly also subjects for applying this powerful tool to analyze current research,challenges and perspectives in this *** is due to the fact that these studies have addressed a great variety of aspects of the application of MSCs for the treatment of chronic wounds,such as using both the cells themselves and their various products:Sponges,hydrogels,exosomes,and genetic *** a wide variety of directions in the field of study and biomedical application of MSCs requires a deep understanding of the current state of research in this area,which can be provided by bibliometric ***,the use of such elements of bibliographic analysis as publication count by year and analysis of top-10 keywords calculated independently or cited from bibliometric analysis studies can be safely recommended for every basic study manuscripts,primarily for the“Introduction”section,and review.

关键词： Bibliometric analysis Mesenchymal stem cells Wound healing Tissue engineering Dressing Hydrogels Matrix Exosomes

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Experimental and numerical investigation of the impacts of rotor tip-rake on excitation forces of pump-jet propulsors

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Journal of Hydrodynamics 2024年第1期36卷 142-157页

作者： Xue-qin Ji Xiao-song Zhang Chen-jun Yang Xiao-qian Dong State Key Laboratory of Ocean Engineering Marine Numerical Experiment CentreSchool of Naval ArchitectureOcean and Civil EngineeringShanghai Jiao Tong UniversityShanghai200240China CSSC Shanghai Marine Energy Saving Technology Co. Ltd.Shanghai200011China China Ship scientific research Center Shanghai Branch Shanghai200011China

The tip-clearance flow in a pump-jet propulsor exerts great impacts on the fluctuating pressures and resultant unsteady forces,which are important sources of structural vibrations and radiated noise *** blade geometry close to the tip is an important factor determining the vortex strength in the tip-clearance *** the open-water condition,the effects of raking the rotor tips on the duct-surface fluctuating pressures and the resultant unsteady forces acting on different components of the propulsor are investigated via physical model experiments and the numerical solution of Reynolds-averaged Navier-Stokes(RANS)equations coupled with the SST k-ωturbulence *** measured and simulated results of hydrodynamic pressures are consistent to each other,and the simulated flows help better understand why the fluctuating pressures change with the tip *** strong fluctuations of duct-surface pressures are caused by intensive tip separation *** duct-surface pressure fluctuations are effectively reduced by using the rake distribution near the tip towards blade back side and,for the combination of the five-bladed rotor and the seven-bladed stator,the resultant unsteady horizontal(and vertical)forces acting on the duct and stator are also reduced;while increasing rake leads to negative effect on pressure fluctuations and unsteady horizontal(and vertical)forces acting on all the components of the propulsor.

关键词： Pump-jet tip-clearance tip-rake fluctuating pressures excitation forces

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