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A bibliometric analysis of molybdenum-based nanomaterials in the biomedical field

Tungsten 2024年第1期6卷 17-47页

作者： Zhi-Qiang Wang Ya-Wen Pan Jing Wu Hong-Bin Qi Shuang Zhu Zhan-Jun Gu School of Science China University of GeosciencesBeijing 100083China cas key laboratory for biomedical eff ects of nanomaterials and nanosafety Institute of High Energy PhysicsBeijing 100049China cas Center for Excellence in Nanoscience National Center for Nanoscience and Technology of ChinaChinese Academy of SciencesBeijing 100190China College of Materials Science and Optoelectronic Technology University of Chinese Academy of SciencesBeijing 100049China

Molybdenum(Mo)-based nanomaterials have been widely used in biomedical fields due to their various nanostructures and unique physical/chemical properties.Although various reviews have described the development of Mo-based materials in the biomedical field,an objective and comprehensive summary and analysis of research trends in this field is still rare.Therefore,we used the bibliometric analysis method to analyze all relevant literature on the biological application of Mobased nanomaterials in recent years.First,we use bibliometric tools to analyze the dataset by year,country/region,institution and research hotspot to obtain the research trends.Next,based on objectively identified research hotspots,the biomedical applications of Mo-based nanomaterials are reviewed comprehensively,mainly including sensors,cancer imaging/therapy and antibacterial applications.Finally,we discussed the application prospects and challenges of Mo-based materials.This article provides a new perspective to understand the current research progress and further promote the development of Mobased nanomaterials in biomedical research.

关键词： Molybdenum Nanomaterial Biomedicine Bibliometric analysis

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Pulse electrochemical synaptic transistor for supersensitive and ultrafast biosensors

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InfoMat 2023年第11期5卷 25-39页

作者： Jianlong Ji Zhenxing Wang Fan Zhang Bin Wang Yan Niu Xiaoning Jiang Zeng-ying Qiao Tian-ling Ren Wendong Zhang Shengbo Sang Zhengdong Cheng Qijun Sun College of Electronics Information and Optical Engineering Taiyuan University of TechnologyTaiyuanthe People’s Republic of China Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of SciencesBeijingthe People’s Republic of China Department of Mechanical and Aerospace Engineering North Carolina State UniversityRaleighNorth CarolinaUSA D Artificial Intelligence biomedical Research Institute Taiyuanthe People’s Republic of China cas key laboratory for biomedical effects of nanomaterials and nanosafety CAS Center for Excellence in NanoscienceNational Center for Nanoscience and Technology(NCNST)Beijingthe People’s Republic of China Institute of Microelectronics Tsinghua UniversityBeijingthe People’s Republic of China College of Chemical and Biological Engineering Zhejiang UniversityHangzhouthe People’s Republic of China

High sensitivity and fast response are the figures of merit for benchmarking commercial sensors.Due to the advantages of intrinsic signal amplification,bionic ability,and mechanical flexibility,electrochemical transistors(ects)have recently gained increasing popularity in constructing various sensors.In the current work,we have proposed a pulse-driven synaptic ECT for supersensitive and ultrafast biosensors.By pulsing the presynaptic input(drain bias,VD)and setting the modulation potential(gate bias)near transconductance intersection(VG,i),the synaptic ECT-based pH sensor can achieve a record high sensitivity up to 124 mV pH^(-1)(almost twice the Nernstian limit,59.2 mV pH^(-1))and an ultrafast response time as low as 8.75 ms(7169 times faster than the potentiostatic sensors,62.73 s).The proposed synaptic sensing strategy can effectively eliminate the transconductance fluctuation issue during the calibration process of the pH sensor and significantly reduce power consumption.Besides,the most sensitive working point at VG,i has been elaborately figured out through a series of detailed mathematical derivations,which is of great significance to provide higher sensitivity with quasi-nonfluctuating amplification capability.The proposed electrochemical synaptic transistor paired with an optimized operating gate offers a new paradigm for standardizing and commercializing high-performance biosensors.

关键词： fast response pH sensor pulse electrochemical transistor supersensitive synaptic transistor

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