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building Simulation 2023年第8期16卷 1481-1498页

作者： Jeetika Malik Handi Chandra Putra Kaiyu Sun Tianzhen Hong building technology and urban system division Lawrence Berkeley National LaboratoryBerkeleyCA 94720USA

Occupant behavior(OB)is one of the significant sources of uncertainty in building performance *** OB modeling has received increased attention in the past decade,research on the degree of granularity or level of detail(LoD)required for representing occupants is still in the nascent *** paper analyzes the modeling and applicability of three LoDs to represent occupants in building performance assessment.A medium-sized prototype office building located in Chicago,Illinois is used as the simulation case *** occupant-centric attributes are adopted to develop the LoDs for OB *** first demonstrate the different modeling approaches required for simulating the three fidelity ***,we illustrate the suitability of the developed LoDs in supporting six building performance use cases across different lifecycle *** study intends to provide guidance for the building simulation community on appropriate OB representation to support various use cases.

关键词： occupant behavior agent-based modeling building performance simulation level of detail fit-for-purpose office buildings

Transport mechanism in chemically reactive hybrid nanofluid flow containing gyrotactic micro-organisms over a curved oscillatory surface

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 177-192页

作者： M.NAVEED M.IMRAN T.ASGHAR Z.ABBAS Department of Mathematics Division of Science and TechnologyUniversity of Education Department of Mathematics The Islamia University of Bahawalpur

This paper examines the transport analysis, including both heat transfer and mass transfer, in hybrid nanofluid flow containing gyrotactic microorganisms towards a curved oscillatory surface. The influence of magnetic fields is also inspected in terms of their physical characteristics. To depict the phenomena of transport, modified versions of both Fick's and Fourier's laws are used. Additionally, the characteristics of both heterogeneous and homogeneous chemical reactions are also incorporated. Utilizing a curvilinear coordinate system, the flow problem is formulated as partial differential equations(PDEs)for momentum, concentration, microorganism field, and energy. An analytical solution to the obtained flow equations is achieved utilizing the homotopy analysis method(HAM).The effects of significant flow parameters on the pressure and microorganism fields, velocity, oscillation velocity, concentration, and temperature distributions are shown via graphs. Furthermore, the variations in skin friction, mass transfer rate, heat transfer rate, and local motile number due to different involved parameters are presented in tables and are analyzed in detail. Graphical results indicate that the curves of velocity and temperature fields are enhanced as the values of the solid volume fraction variables *** is also verified that the concentration rate field decreases as the values of the homogeneous reaction strength parameter and the radius of curvature parameter increase, and it increases with the Schmidt number and the heterogeneous reaction strength *** outcomes show a favorable response of the motile number to advanced values of the Peclet number, the Schmidt number, the microorganism difference parameter, and the bio-convective Lewis number.

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Mechanism by which Rab5 promotes regeneration and functional recovery of zebrafish Mauthner axons

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Neural Regeneration Research 2025年第6期20卷 1816-1824页

作者： Jiantao Cui Yueru Shen Zheng Song Dinggang Fan Bing Hu Center for Advanced Interdisciplinary Science and Biomedicine of IHM Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina

Rab5 is a GTPase protein that is involved in intracellular membrane trafficking. It functions by binding to various effector proteins and regulating cellular responses, including the formation of transport vesicles and their fusion with the cellular membrane. Rab5 has been reported to play an important role in the development of the zebrafish embryo;however, its role in axonal regeneration in the central nervous system remains unclear. In this study, we established a zebrafish Mauthner cell model of axonal injury using single-cell electroporation and two-photon axotomy techniques. We found that overexpression of Rab5 in single Mauthner cells promoted marked axonal regeneration and increased the number of intra-axonal transport vesicles. In contrast, treatment of zebrafish larvae with the Rab kinase inhibitor CID-1067700markedly inhibited axonal regeneration in Mauthner cells. We also found that Rab5 activated phosphatidylinositol 3-kinase(PI3K) during axonal repair of Mauthner cells and promoted the recovery of zebrafish locomotor function. Additionally, rapamycin, an inhibitor of the mechanistic target of rapamycin downstream of PI3K, markedly hindered axonal regeneration. These findings suggest that Rab5 promotes the axonal regeneration of injured zebrafish Mauthner cells by activating the PI3K signaling pathway.

关键词： axonal regeneration Mauthner cell nerve regeneration Rab5 zebrafish

Mechanistic insight into the synergy between nickel single atoms and nanoparticles on N-doped carbon for electroreduction of CO2

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Journal of Energy Chemistry 2025年第1期100卷 327-336页

作者： Mingdong Sun Wenwen Guan Cailing Chen Chao Wu Xiaoling Liu Biao Meng Tao Chen Yu Han Jun Wang Shibo Xi Yu Zhou State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical Engineering Nanjing Tech University Advanced Membranes and Porous Materials Center Physical Sciences and Engineering Division King Abdullah University of Science and Technology Institute of Sustainability for Chemicals Energy and Environment A*STAR (Agency for Science Technology and Research) College of Materials Science and Engineering Sichuan University

The synergy of single atoms （SAs） and nanoparticles （NPs） has demonstrated great potential in promoting the electrocatalytic carbon dioxide reduction reaction （CO2RR）;however,the rationalization of the SAs/NPs proportion remains one challenge for the catalyst ***,a Ni2+-loaded porous poly（ionic liquids）(PIL) precursor synthesized through the free radical self-polymerization of the ionic liquid monomer,1-allyl-3-vinylimidazolium chloride,was pyrolyzed to prepare the Ni,N co-doped carbon materials,in which the proportion of Ni SAs and NPs could be facilely modulated by controlling the annealing *** catalyst Ni-NC-1000 with a moderate proportion of Ni SAs and NPs exhibited high efficiency in the electrocatalytic conversion of CO2into *** Ni K-edge X-ray absorption near-edge structure （XANES） spectra and theoretical calculations were conducted to gain insight into the synergy of Ni SAs and *** charge transfer from Ni NPs to the surrounding carbon layer and then to the Ni SAs resulted in the electron-enriched Ni SAs active *** the electroreduction of CO2,the coexistence of Ni SAs and NPs strengthened the CO2activation and the affinity towards the key intermediate of*COOH,lowering the free energy for the potential-determining*CO2→*COOH step,and therefore promoted the catalysis efficiency.

关键词： Single atom catalyst Synergy effect Carbon catalyst Electrocatalysis

From waste to wealth:Coal tar residue derived carbon materials as low-cost anodes for potassium-ion batteries

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 464-475页

作者： Zhonghua Lu Jun Shen Xin Zhang Lingcong Chao Liang Chen Ding Zhang Tao Wei Shoudong Xu College of Chemical Engineering and technology Taiyuan University of TechnologyTaiyuan 030024China College of Chemistry Taiyuan University of TechnologyTaiyuan 030024China School of Chemical Engineering and Pharmacy Wuhan Institute of TechnologyWuhan 430205China School of Energy and Power Jiangsu University of Science and TechnologyZhenjiang 212003China

Carbon materials are widely recognized as highly promising electrode materials for various energy storage system *** tar residues(CTR),as a type of carbon-rich solid waste with high value-added utilization,are crucially important for the development of a more sustainable *** this study,we employed a straightforward direct carbonization method within the temperature range of 700-1000℃to convert the worthless solid waste CTR into economically valuable carbon materials as anodes for potassium-ion batteries(PIBs).The effect of carbonization temperature on the microstructure and the potassium ions storage properties of CTR-derived carbons(CTRCs)were systematically explored by structural and morphological characterization,alongside electrochemical performances *** on the co-regulation between the turbine layers,crystal structure,pore structure,functional groups,and electrical conductivity of CTR-derived carbon carbonized at 900℃(CTRC-900H),the electrode material with high reversible capacity of 265.6m Ah·g^(-1)at 50 m A·g^(-1),a desirable cycling stability with 93.8%capacity retention even after 100 cycles,and the remarkable rate performance for PIBs were ***,cyclic voltammetry(CV)at different scan rates and galvanostatic intermittent titration technique(GITT)have been employed to explore the potassium ions storage mechanism and electrochemical kinetics of *** indicate that the electrode behavior is predominantly governed by surface-induced capacitive processes,particularly under high current densities,with the potassium storage mechanism characterized by an“adsorption-weak intercalation”*** work highlights the potential of CTR-based carbon as a promising electrode material category suitable for high-performance PIBs electrodes,while also provides valuable insights into the new avenues for the high value-added utilization of CTR.

关键词： coal tar residue carbon materials anode potassium-ion batteries high value-added

Towards climate resilient urban energy systems: a review

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National Science Review 2021年第3期8卷 159-176页

作者： Vahid M.Nik A.T.D.Perera Deliang Chen division of building Physics Department of Building and Environmental Technology Lund University Institute for Future Environments(IFE) Queensland University of Technology(QUT) Regional Climate Group Department of Earth SciencesUniversity of Gothenburg division of building technology Department of Architecture and Civil Engineering Chalmers University of Technology Solar Energy and building Physics Laboratory(LESO-PB) Ecole Polytechnique Federale de Lausanne(EPFL) urban Energy systems Laboratory

Climate change and increased urban population are two major concerns for *** towards more sustainable energy solutions in the urban context by integrating renewable energy technologies supports decarbonizing the energy sector and climate change mitigation.A successful transition also needs adequate consideration of climate change including extreme events to ensure the reliable performance of energy systems in the long *** review provides an overview of and insight into the progress achieved in the energy sector to adapt to climate change,focusing on the climate resilience of urban energy *** state-of-the-art methodology to assess impacts of climate change including extreme events and uncertainties on the design and performance of energy systems is described and *** resilience is an emerging concept that is increasingly used to represent the durability and stable performance of energy systems against extreme climate ***,it has not yet been adequately explored and widely used,as its definition has not been clearly articulated and assessment is mostly based on qualitative *** study reveals that a major limitation in the state-of-the-art is the inadequacy of climate change adaptation approaches in designing and preparing urban energy systems to satisfactorily address plausible extreme climate ***,the complexity of the climate and energy models and the mismatch between their temporal and spatial resolutions are the major limitations in linking these ***,few studies have focused on the design and operation of urban energy infrastructure in terms of climate *** the occurrence of extreme climate events and increasing demand for implementing climate adaptation strategies,the study highlights the importance of improving energy system models to consider future climate variations including extreme events to identify climate resilient energy transition pathways.

关键词： climate resilience climate change adaptation urban energy systems renewable energy extreme events decentralized generation

Brain region-specific roles of brain-derived neurotrophic factor in social stress-induced depressive-like behavior

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Neural Regeneration Research 2025年第1期20卷 159-173页

作者： Man Han Deyang Zeng Wei Tan Xingxing Chen Shuyuan Bai Qiong Wu Yushan Chen Zhen Wei Yufei Mei Yan Zeng Brain Science and Advanced technology Institute Wuhan University of Science and TechnologyWuhanHubei ProvinceChina Geriatric Hospital Affiliated to Wuhan University of Science and technology WuhanHubei ProvinceChina School of Public Health Wuhan University of Science and TechnologyWuhanHubei ProvinceChina

Brain-derived neurotrophic factor is a key factor in stress adaptation and avoidance of a social stress behavioral *** studies have shown that brain-derived neurotrophic factor expression in stressed mice is brain region–specific,particularly involving the corticolimbic system,including the ventral tegmental area,nucleus accumbens,prefrontal cortex,amygdala,and *** how brain-derived neurotrophic factor participates in stress processing in different brain regions will deepen our understanding of social stress *** this review,we discuss the expression and regulation of brain-derived neurotrophic factor in stress-sensitive brain regions closely related to the pathophysiology of *** focused on associated molecular pathways and neural circuits,with special attention to the brain-derived neurotrophic factor–tropomyosin receptor kinase B signaling pathway and the ventral tegmental area–nucleus accumbens dopamine *** determined that stress-induced alterations in brain-derived neurotrophic factor levels are likely related to the nature,severity,and duration of stress,especially in the above-mentioned brain regions of the corticolimbic ***,BDNF might be a biological indicator regulating stress-related processes in various brain regions.

关键词： amygdala chronic mild stress chronic social defeat stress corticolimbic system depression hippocampus medial prefrontal cortex nucleus accumbens social stress models ventral tegmental area

What decarbonized the residential building operation worldwide since the 2000s

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Petroleum Science 2022年第6期19卷 3194-3208页

作者： Min-Da Ma Min-Xia Chen Wei Feng Jing-Wen Huo building technology&urban systems division Lawrence Berkeley National LaboratoryBerkeleyCA 94720United States School of Management Science and Real Estate Chongqing UniversityChongqing400045PR China Department of Earth system Science Tsinghua UniversityBeijing100084PR China

Decarbonization in operational residential buildings worldwide has become critical in achieving the carbon neutral target due to the growing household energy *** accelerate the pace of global carbon neutrality,this study explores the operational carbon change in global residential buildings through the generalized Divisia index method and decoupling analysis,considering the decarbonization levels of residential buildings at different *** results show that(1)most of the samples showed a decrease in the total emissions from 2000 to *** for China and the United States(US),the carbon emissions in global residential building operations decreased by 7.95 million tons of carbon dioxide(MtCO_(2))per year over the study *** per gross domestic product(GDP)was the most positive driver causing the decarbonization of residential buildings,while GDP was the most negative driver.(2)Carbon intensity was essential to achieving a strong decoupling of economic development and carbon *** US almost consistently presented strong decoupling,while China showed weak decoupling over the last two decades.(3)The pace of decarbonization in global residential building operations is gradually slowing *** 2000 to 2019,decarbonization from residential buildings across 30 countries was 2094.3 MtCO_(2),with a decarbonization efficiency of 3.4%.Overall,this study addresses gaps in evaluating global decarbonization from operational residential buildings and provides a reference for evaluating building decarbonization by other emitters.

关键词： Global residential building Operational decarbonization Generalized divisia index method Decoupling elasticity building decarbonization strategies

Formation control with disturbance rejection for a class of Lipschitz nonlinear systems

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Science China(Information Sciences) 2017年第7期60卷 29-39页

作者： Chunyan WANG Zongyu ZUO Qinghai GONG Zhengtao DING School of Electrical and Electronic Engineering University of Manchester Sackville Street Building Sino-British Joint Advanced Control system technology Laboratory James Lighthill Building The Seventh Research division and Science and Technology on Aircraft Control Laboratory Beihang University Beijing Aerospace Automatic Control Institute

In this paper, we consider the leader-follower formation control problem for general multi-agent systems with Lipschitz nonlinearity and unknown disturbances. To deal with the disturbances, a disturbance observer-based control strategy is developed for each follower. Then, a time-varying formation protocol is proposed based on the relative state of the neighbouring agents and sufficient conditions for global stability of the formation control are identified using Lyapunov method in the time domain. The proposed strategy and analysis guarantee that all signals in the closed-loop dynamics are uniformly ultimately bounded and the formation tracking errors converge to an arbitrarily small residual set. Finally, the validity of the proposed controller is demonstrated through a numerical example.

关键词： multi-agent systems formation control Lipschitz nonlinearity disturbance rejection

Impact of weather conditions and building design on contaminant infiltration from crawl spaces in Swedish schools-Numerical modeling using Monte Carlo method

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building Simulation 2022年第5期15卷 845-858页

作者： Fredrik Domhagen Paula Wahlgren Carl-Eric Hagentoft Department for Architecture and Civil Engineering Division of Building TechnologyChalmers University of TechnologySE-41296GothenburgSweden

Some Swedish school buildings built in the 1960s and 1970s experience indoor air quality problems,where the contaminants are suspected to come from the crawl space underneath the *** poor indoor air quality causes discomfort among pupils and *** an exhaust fan to maintain a negative pressure difference in the crawl space relative to indoors or increasing the ventilation in the classroom are two examples of common measures taken to improve the indoor air ***,these measures are not always effective,and sometimes the school building has to be *** relation between pressure distribution,contaminant concentration in the classroom,outdoor temperature,wind,mechanical ventilation,and air leakage distribution is complex.A better understanding of these relations is crucial for making decisions on the most efficient measure to improve the indoor air *** this paper,a model for contaminant infiltration from the crawl space is used together with the Monte Carlo method to study these *** are performed for several cases where different building shapes,building orientations,shielding conditions,and geographical locations are *** show,for example,that for a building with an imbalanced ventilation system,air is leaking from the crawl space to the classroom for the majority of cases and that concentration levels in the classroom are usually the highest during mild and calm days.

关键词： airtightness air permeability Monte Carlo method infiltration model crawl space indoor air quality