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Pressure ulcers and acute risk factors in individuals with traumatic spinal fractures with or without spinal cord injuries:A prospective analysis of the National Spinal Column/Cord injury Registry of Iran(NSCIR-IR)data

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Chinese Journal of Traumatology 2023年第4期26卷 193-198页

作者： Farzin Farahbakhsh Hossein Rezaei Aliabadi Vali Baigi Zahra Ghodsi Mohammad Dashtkoohi Ahmad Pour-Rashid James SHarrop Vafa Rahimi-Movaghar Sina and Trauma Surgery research center Tehran University of Medical SciencesTehranIran brain and spinalcord injury research center neuroscienceinstute Tehran Universityof Medical SciencesTehranIran Department of Neurosurgery Shariati HospitalTehran University of Medical SciencesTehranIran Sports Medicine research center Tehran University of Medical SciencesTehranIran School of Medicine Bam University of Medical SciencesBamIran Students'Scientific research center(SSRC) Tehran University of Medical SciencesTehranIran Department of Neurosurgery Sina HospitalTehran University of Medical SciencesTehranIran Department of Neurosurgery Thomas Jefferson UniversityPhiladelphiaUSA Universal Scientific Education and research Network(USERN) TehranIran Institute of Biochemistry and Biophysics University of TehranTehranIran Spine Program University of TorontoTorontoCanada

Purpose:To identify risk factors for developing pressure ulcers(PUs)in the acute care period of traumatic spinal fracture patients with or without spinal cord injuries(SCIs).Methods:Data were collected prospectively in participating the National Spinal column/Cord injury Registry of Iran(NSCIR-IR)from individuals with traumatic spinal fractures with or without SCIs,in-clusive of the hospital stay from admission to *** nursing staff examined the patients for the presence of PUs every 8 h during their hospital *** presence and grade of PUs were assessed according to the European Pressure Ulcer Advisory Panel *** addition to PU,following data were also extracted from the NSCIR-IR datasets during the period of 2015-2021:age,sex,Glasgow coma scale score at admission,having SCIs,marital status,surgery for a spinal fracture,American Spinal injury Association impairment scale(AIS),urinary incontinence,level of education,admitted center,length of stay in the intensive care unit(ICU),hypertension,respiratory diseases,consumption of ciga-rettes,diabetes mellitus and length of stay in the *** regression models were used to es-timate the unadjusted and adjusted odds ratio(OR)with 95%confidence intervals(CI).Results:Altogether 2785 participants with traumatic spinal fractures were *** them,87(3.1%)developed PU during their hospital stay and 392(14.1%)had *** the SCI population,63(16.1%)developed PU during hospital *** logistic regression for the whole sample showed that marital status,having SCIs,urinary incontinence,level of education,treating center,number of days in the ICU,age,and Glasgow coma scale score were significant predictors for ***,further analysis by multiple logistic regression only revealed the significant risk factors to be the treating center,marital status,having SCIs,and the number of days in the *** the subgroup of individuals with SCIs,marital status,AIS,urinary incontinenc

关键词： Spinal fractures Spinal cord injuries Pressureulcer NSCIR-IR

RESTITUTION OF UPPER-LIMB MOVEMENT PROMOTED WITH FUNCTIONAL ELECTRICAL THERAPY (FET)

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神经解剖学杂志 2001年第B7期17卷 88-91页

作者： Dejan POPOVIC Mirjana POPOVIC Thomas SINKJ■ER center for Sensory Motor Interaction Aalbory UniversitYDenmark center for Sensory Motor Interaction Aalbory UniversitYDenmark Institute for Medical Research Belgrade Yugoslavia

The neurorehabilitation is a term that relates to methods and technologies for maximising the functioning of impaired sensory-motor mechanisms in human after central nervous system (CNS) injury (e.g., spinalcord injury, and stroke). Maximising function relates to developing new sensory-motor pathways and CNS strategies that could benefit from the available, yet unused sensory-motor mechanisms. The CNS provides the basis for structuring neurorehabilitation activities to promote and enhance recovery of function following the injury

关键词： PET 功能性电疗法上肢活动康复

Strategies for myelin regeneration: lessons learned from development

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Neural Regeneration research 2014年第14期9卷 1347-1350页

作者： Abhay Bhatt Lir-Wan Fan Yi Pang Department of Pediatrics Division of Newborn MedicineUniversity of Mississippi Medical CenteracksonMSUSA

Myelin regeneration is indispensably important for patients suffering from several central nervous system （CNS） disorders such as multiple sclerosis （MS） and spinal cord injury （SCI）, because it is not only essential for restoring neurophysiology, but also protects denuded axons for secondary degeneration. Understanding the cellular and molecular mechanisms underlying remyelination is critical for the development of remyelination-specific therapeutic approaches. As remyelination shares certain common mechanisms with developmental myelination, knowledge from study of developmental myelination contributes greatly to emerging myelin regeneration therapies, best evidenced as the recently developed human anti-Nogo receptor interacting protein-1 （LINGO-1） monoclonal antibodies to treat MS patients in clinical trials.

关键词： oligodendrocyte myelination microglia multiple sclerosis white matter damage spinalcord injury