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Assessment of Maxillary and Mandibular bone Mineral density in Controlled Type II Diabetes in Completely Edentulous Patients Using Cone-Beam Computed Tomography—A Cross Sectional Study with Comparison group

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Open Journal of Stomatology 2021年第10期11卷 422-436页

作者： Sushant M. Patil Arun N. Khalikar Suryakant C. Deogade Amit R. Parate Snehal Bansod Dinesh Naitam Department of Prosthodontics and Crown and Bridge Government Dental College and Hospital Nagpur Maharashtra India Department of Oral Diagnosis Medicine and Maxillofacial Radiology Government Dental College and Hospital Aurangabad Maharashtra India Department of Oral and Maxillofacial Surgery Matri Dental College and Research Centre Anjora Durg Chhattisgarh India Department of Dentistry Government Medical College and Hospital Akola Maharashtra India

This study was undertaken to assess and compare bone mineral density in nondiabetic and controlled diabetic subjects using cone beam computed tomography. A group of 60 completely edentulous patients, comprising of 30 nondiabetic and 30 controlled type 2 diabetics between the age group of 45 - 75 years, were enrolled in the study. Glycemic control of the diabetics was assessed using glycosylated hemoglobin test and level between 6.1% - 8% was considered controlled. A radiographic stent was fabricated for each patient by using chemically cured transparent acrylic resin. bone densities at trabecular, buccal and lingual cortical regions of maxillary and mandibular ridges were measured by a cone beam tomography machine in Hounsfield units. The data thus obtained at 10 prospective oral implant sites of maxillary and mandibular ridges were tabulated and analyzed using STATA, version 14.0 statistical software. This study results showed no significant changes in the bone mineral density between the nondiabetic and controlled diabetic subjects. Within the limitations of this study, it can be concluded that bone mineral density does not seem to be affected in controlled type 2 diabetic patients.

关键词： Diabetes bone density Tomography Dental Implants

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The bone alterations in hind limb amputation rats in vivo

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Medicine in Novel Technology and Devices 2020年第4期8卷 31-35页

作者： Huiqin Luan Huiru gu Zhongjun Mo Weiyan Ren Huan Guo Zhaowei Chu Yubo Fan Key Laboratory of Intelligent Control and Rehabilitation Technology of the Ministry of Civil Affairs National Research Center for Rehabilitation Technical AidsBeijing100176China Beijing Key Laboratory of Rehabilitation Technical Aids for Old-Age Disability Beijing100176China Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education School of Biological Science and Medical EngineeringBeihang UniversityBeijing100191China Key Laboratory of Rehabilitation Technical Aids Analysis and Identification of the Ministry of Civil Affairs Beijing100176China

Osteoporosis,which is characterized by bone loss,increases the risk of fractures and s and seriously affected the amputee’s *** mass is an important factor affecting bone mineral density(BMD).Muscular atrophy and decreased muscle mass can cause BMD to *** bone quantity and quality are used to assess by Microcomputer tomography(micro-CT)with *** investigate the performance of micro-CT in evaluating amputation-induced osteopenia in rats,the micro-CT was used to evaluate the change of the microstructure in trabecular bone and cortical bone of *** morphology was analyzed by micro-CT and transmission electron *** Sprague–Dawley rats(8 week old)were divided into two groups:control(CON)groups and left hind limb amputation(LHLA).At 35 days,microstructure and volumetric bone mineral density(vBMD)of the tibia and femur were detected through *** results showed:(1)the trabecular and cortical vBMD of the proximal tibia and distal femur in the LHLA group were significantly lower than those in the CON group.(2)Compared with the CON group,the trabecular number,bone volume fraction and trabecular thickness of proximal tibia and distal femur in LHLA group decreased significantly,whereas the trabecular separation,structure model index and bone surface/bone volume increased significantly in LHLA group.(3)The whole cross-sectional area(CSA)of whole calf muscles of left limb in LHLA group decreased significantly compared with CON *** general,hind limb amputation could cause bone loss,changes in the microstructure of trabecular bone and muscle ***-CT is sensitive in evaluating bone microstructure destruction caused by amputation,and can be used for early diagnosis or monitor the development of bone loss in amputation in vivo.

关键词： Amputation Micro-CT Microstructure bone loss BMD

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