检索结果-南通市图书馆

Single-cell pan-omics, environmental neurology, and artificial intelligence:the time for holistic brain health research

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第6期20卷 1703-1704页

作者： Paolo Abondio Francesco Bruno IRCCS Istituto delle Scienze Neurologiche di bologna BolognaItaly Association for Neurogenetic Research(ARN) Lamezia TermeCatanzaroItaly

The brain,with its trillions of neural connections,different cellular types,and molecular complexities,presents a formidable challenge for researchers aiming to comprehend the multifaceted nature of neural *** traditional methods have provided valuable insights,emerging technologies offer unprecedented opportunities to delve deeper into the underpinnings of brain *** the everevolving landscape of neuroscience,the quest to unravel the mysteries of the human brain is bound to take a leap forward thanks to new technological improvements and bold interpretative frameworks.

关键词： function artificial landscape

Local recurrence rate as quality indicator in surgery for pancreatic cancer?

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2024年第5期23卷 548-550页

作者： Carlo Alberto Pacilio Alessandro Cucchetti Giorgio Ercolani General and Oncologic Surgery Unit Morgagni-Pierantoni HospitalAUSL RomagnaVia Carlo Forlanini 3447121ForlìItaly Department of Medical and Surgical Sciences Alma Mater StudiorumUniversity of BolognaVia Massarenti 940138BolognaItaly

To the Editor: As we all know, even with the current advancements regarding novel chemotherapy regimens, patients affected by pancreatic cancer(PC) have an extremely dismal prognosis(5-year survival rate 12% for all stages in the National Cancer Institute SEER database). Among the patients undergoing surgical treatment, the prognosis is mostly affected by recurrence. PC after surgery has mainly four patterns of recurrence, isolated or variously associated with each other: local, lymph nodal, peritoneal or distant(liver, lung, other sites).

关键词： surgery prognosis cancer

Pain in chronic pancreatitis:What can we do today?

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Methodology 2024年第3期14卷 30-39页

作者： Margherita Binetti Valeria Tonini Department of Medical and Surgical Science University of BolognaAlma mater StudiorumBologna 40138Italy

The aim of this study is to illustrate the complexity of pain management in chronic pancreatitis(CP).In this context,pain represents the most common and debilitating symptom,and it deeply affects patient’s quality of *** rating scales(unidimensional,bidimensional and multidimensional)have been proposed to quantify CP ***,it represents the result of complex mechanisms,involving genetic,neuropathic and neurogenic *** all these aspects,the treatment should be discussed in a multidisciplinary setting and it should be approached in a stepwise ***,a lifestyle change is recommended and nonsteroidal anti-inflammatory drugs represent the gold standard among medical treatments for CP *** second step,after medical approach,is endoscopic therapy,especially for complicated *** case of failure,tailored surgery represents the third step and decompressive or resection procedures can be *** conclusion,CP pain’s management is challenging considering all these complex aspects and the lack of international protocols.

关键词： Chronic pancreatitis Pain Multifactorial mechanism Stepwise approach Endoscopic treatment Early surgery

Towards a new frontier in wrist rehabilitation:The traction-free posture orthosis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Medicine in Novel Technology and Devices 2024年第3期23卷 136-138页

作者： Paolo Boccolari Roberto Tedeschi Danilo Donati Azienda Ospedaliero Universitaria di Modena PoliclinicoItaly Department of Biomedical and Neuromotor Sciences Alma Mater StudiorumUniversity of BolognaBolognaItaly Physical Therapy and Rehabilitation Unit Policlinico di ModenaModenaItaly Clinical and Experimental Medicine PhD Program University of Modena and Reggio EmiliaModenaItaly

This study presents the novel Traction-Free Posture Orthosis,designed to address wrist stiffness without the use of traditional traction *** orthosis employs a velcro system to stabilize the position of the wrist in flexion or extension,thereby avoiding the compression and rotational disadvantages associated with non-perpendicular traction ***-shaped cuts in the brace allow for plastic material flexibility,ensuring movement and *** is the absence of a traction strap,which traditionally reduces the support surface and could create pressure points leading to patient discomfort or treatment *** design facilitates a wide contact surface with the hand,optimal load distribution,and the capacity to adjust dual traction straps independently,adapting to the natural wrist *** single-piece base orthosis offers a stable,cost-effective,and patientfriendly alternative to conventional ***,patients with stiffness in both flexion and extension may require two separate orthoses,potentially increasing costs and patient ***,the Traction-Free Posture Orthosis represents an innovative step in wrist rehabilitation,providing a quick-to-construct,easy-to-wear solution with the promise of enhanced patient compliance and comfort.

关键词： Wrist rehabilitation Orthotic devices Hand therapy Occupational therapy

Hybrid robust fault detection and isolation of satellite reaction wheel actuators

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Control and Decision 2024年第1期11卷 117-131页

作者： H.Abbasi Nozari S.J.Sadati Rostami Paolo Castaldi Silvio Simani Faculty of Electrical and Computer Engineering Babol Noshirvani University of TechnologyBabolIran Department of Electrical Electronic and Information EngineeringUniversity of BolognaCesenaItaly Department of Engineering University of FerraraFerraraItaly

In this paper,a combined robust fault detection and isolation scheme is studied for satellite system subject to actuator faults,external disturbances,and parametric *** proposed methodology incorporates a residual generation module,including a bank of filters,into an intelligent residual evaluation ***,residual filters are designed based on an improved nonlinear differential algebraic approach so that they are not affected by external *** residual evaluation module is developed based on the suggested series and parallel ***,a new ensemble classification scheme defined as blended learning integrates heterogeneous classifiers to enhance the performance.A wide range of simulations is carried out in a high-fidelity satellite simulator subject to the constant and time-varying actuator faults in the presence of disturbances,manoeuvres,uncertainties,and *** obtained results demonstrate the effectiveness of the proposed robust fault detection and isolation method compared to the traditional nonlinear differential algebraic approach.

关键词： Robust fault detection and isolation reaction wheels blended learning series and parallel fault detection and isolation forms satellite attitude control system

Geophysical evidence of large-scale silica-rich fluid flow above the continental subduction interface

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Earth Sciences 2024年第9期67卷 2796-2809页

作者： Yuantong MAO Liang ZHAO Marco G.MALUSA Stefano SOLARINO Silvia PONDRELLI Baolu SUN Coralie AUBERT Simone SALIMBENI Elena EVA Stéphane GUILLOT State Key Laboratory of Lithospheric and Environmental Coevolution Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijing 100049China Department of Earth and Environmental Sciences University of Milano-BicoccaMilan 20126Italy Istituto Nazionale di Geofisica e Vulcanologia Osservatorio Nazionale TerremotiGenova 16145Italy Istituto Nazionale di Geofisica e Vulcanologia Sezione di BolognaBologna 40127Italy univ.rsité Grenoble Alpes Université Savoie Mont BlancCNRSIRDUGEISTerreGrenoble 38000France

Fluids in subduction zones can have major effects on subduction ***,geophysical constraints on the scale and impact of fluid flow during continental subduction are still *** we analyze the VP/VS ratios in the Western Alpine region,hosting one of the best-preserved fossil continental subduction zones worldwide,to investigate the impact of fluid flow during continental *** found a belt of high VP/VS ratios>1.9 on the upper-plate side of the subduction zone,consistent with a partially serpentinized upper-plate mantle,and a belt of unusually low VP/VS ratios<1.7 on the lower-plate side,at depths shallower than 30 *** propose that these low VP/VS ratios result from a widespread network of silica-rich veins,indicating past fluid flow along the continental subduction *** results suggest that past fluid flow may have reduced the effective stress along the subduction interface thus favoring continental subduction.

关键词： Western Alps Crustal structure Receiver function Vp/Vs ratio Silica enrichment

Ultrasound,contrast-enhanced ultrasound and pyelonephritis:A narrative review

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Nephrology 2024年第3期13卷 1-8页

作者： Andrea Boccatonda Roberta Stupia Carla Serra Department of Medical and Surgical Sciences(DIMEC) University of BolognaBologna 40126Italy Department of General Medicine C Azienda Ospedaliera Universitaria Integrata of VeronaUniversity of VeronaVerona 37134Italy Department of Medical Liver Transplant Care General and University Hospital S.Orsola-MalpighiBologna 40138Italy

Acute pyelonephritis(APN)is a bacterial infection resulting in kidney inflammation,typically arising as a complication of an ascending urinary tract infection that ascends from the bladder to the *** diagnosis is generally based on clinical and laboratory *** guidelines recommend not performing diagnostic imaging unless a complicated APN is suspected or the infection affects high-risk patients such as the elderly,immunocompromised individuals,or ***-enhanced ultrasound(CEUS)is a valuable tool in both the diagnosis and follow-up of *** aids in distinguishing small simple nephritic involvement from abscess complications and monitoring their evolution over time during antibiotic *** its lack of ionizing radiation and nephrotoxicity,CEUS is a valid diagnostic modality for approaching and monitoring pyelonephritis,improving early identification and characterization of inflammatory *** review aims to summarize the main evidence on the use of ultrasound and CEUS in the diagnosis of APN and its follow-up.

关键词： Pyelonephritis Contrast-enhanced ultrasound Kidney Abscess Urinary infection

Loss of the accessory chromosome converts a pathogenic tree-root fungus into a mutualistic endophyte

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Plant Communications 2024年第1期5卷 164-180页

作者： Huanshen Wei Zhenhui Zhong Zhongfeng Li Yuwei Zhang Eva H.Stukenbrock Boping Tang Ningning Yang Riccardo Baroncelli Long Peng Zhuo Liu Xinghua He Yuzhan Yang Zhilin Yuan State Key Laboratory of Tree Genetics and Breeding Chinese Academy of ForestryBeijing 100091China Research Institute of Subtropical Forestry Chinese Academy of ForestryHangzhou 311400China State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops Fujian Agriculture and Forestry UniversityFuzhou 350002China Environmental Genomics Christian-Albrechts University24118 KielGermany Max Planck Fellow Group Environmental Genomics Max Planck Institute for Evolutionary Biology24306 PlonGermany Jiangsu Key Laboratory for Bioresources of Saline Soils School of WetlandsYancheng Teachers UniversityYancheng 224002China Department of Agricultural and Food Sciences(DISTAL) University of Bologna40127 BolognaItaly

Some fungal accessory chromosomes(ACs)may contribute to virulence in ***,the mecha-nisms by which ACs determine specific traits associated with lifestyle transitions along a symbiotic contin-uum are not *** we delineated the genetic divergence in two sympatric but considerably variable isolates(16B and 16W)of the poplar-associated fungus Stagonosporopsis *** identified a-0.6-Mb horizontally acquired AC in 16W that resulted in a mildly parasitic lifestyle in *** deletion of the AC(D16W)significantly altered the fungal ***,D16W was morphologically more similar to 16B,showed enhanced melanization,and established beneficial interactions with poplar plants,thereby acting as a dark septate *** sequencing(RNA-seq)analysis showed that AC loss induced the upregulation of genes related to root colonization and biosynthesis of indole acetic acid and *** observed that the AC maintained a more open status of chromatin across the genome,indicating an impressive remodeling of cis-regulatory elements upon AC loss,which potentially enhanced symbiotic *** demonstrated that the symbiotic capacities were non-host-specific through comparable experiments on Triticum–and Arabidopsis–fungus ***,the three isolates generated symbiotic interactions with a nonvascular *** summary,our study suggests that the AC is a suppressor of symbiosis and provides insights into the underlying mechanisms of mutualism with vascular plants in the absence of traits encoded by the *** speculate that AC-situ-ated effectors and other potential secreted molecules may have evolved to specifically target vascular plants and promote mild virulence.

关键词： dark septate endophytes effectors lifestyle transition root–fungus symbioses

New insights on portal hypertension’s screening in people with cystic fibrosis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary Surgery and Nutrition 2024年第5期13卷 894-897页

作者： Luigi Colecchia Federico Ravaioli Giovanni Marasco Elton Dajti Antonio Colecchia Department of Medical and Surgical Sciences(DIMEC) University of BolognaBolognaItaly Department of Visceral Surgery and Medicine InselspitalBern University HospitalBernSwitzerland Gastroenterology Unit Department of Medical Specialities(CHIMOMO)University of Modena and Reggio EmiliaModenaItaly

Cystic fibrosis-associated liver disease(CFLD)is a significant cause of morbidity and mortality affecting people with cystic fibrosis(PwCF)(1).Approximately 40%of PwCF have liver involvement,defined as the existence of any hepatic manifestation,including biochemical liver abnormalities(2).In a small percentage of these patients,liver involvement may ultimately result in the development of portal hypertension(PH)and its *** presence of at least two of the following variables-abnormal liver tests,abnormal liver ultrasound(US),abnormal physical examination with hepatosplenomegaly or histologic evidence of liver disease-were historically the basis for the European criteria to define CFLD(3).Nevertheless,the emergence of a new approach for liver assessment as liver elastography has led to the proposal of its inclusion in new diagnostic criteria(4).

关键词： Porto-sinusoidal vascular disease(PSVD) portal hypertension cystic fibrosis liver stiffness spleen stiffness