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Structural and temporal dynamics analysis on drug-eluting stents: History, research hotspots and emerging trends

Bioactive Materials 2023年第5期23卷 170-186页

作者： Lili Tan Xiangxiu Wang Kungshan Yuan Tieying Yin Ruolin Du Li Shen Zhirong Zhu Suhua Yu Haijun Zhang Guixue Wang Key laboratory of Biorheological and Technology of Ministry of Education State and Local Joint Engineering Laboratory for Vascular ImplantsModern Life Science Experiment Teaching Center at Bioengineering College of Chongqing UniversityChongqing400030China National United Engineering laboratory for Biomedical Material Modification Shandong Rientech Medical Tech Co.LtdDezhouShandong251100China Department of Cardiology Zhongshan HospitalFudan UniversityShanghai Institute of Cardiovascular DiseasesShanghaiNational Clinical Research Center for Interventional MedicineShanghai200032China Shanghai Key lab of Chemical Assessment and Sustainability School of Chemical Science and EngineeringTongji UniversityShanghai200092China blue sail pioneer lab JW Medical SystemsJiwei Shandong264200China JinFeng laboratory Chongqing401329China

Purpose:This review aims to explore the history,research hotspots,and emerging trends of drug-eluting stents(DES)in the last two decades from the perspective of structural and temporal ***:Publications on DES were retrieved from *** bibliometric tools including CiteSpace and HistCite were used to identify the historical features,the evolution of active topics,and emerging trends on the DES ***:In the last 20 years,the field of DES is still in the hot phase and there is a wide range of extensive scientific *** addition,active topics emerge in different periods,as evidenced by a total of 41 disciplines,511 keywords,and 1377 papers with citation *** clustering anchored five emerging research subfields,namely#0 dual antiplatelet therapy,#3 drug-coated balloon,#4 bifurcation,5#rotational atherectomy,and 6#quantitative flow *** keyword alluvial map shows that the most persistent research concepts in this field are thrombosis,restenosis,etc.,and the emerging keywords are paclitaxel eluting balloon,coated balloon,drug-eluting balloon,*** are 7 recent research subfields anchored by reference clustering,namely#2 dual antiplatelet therapy,#4 drug-coated balloon,#5 peripheral artery disease,#8 fractional flow reserve,#10 bioresorbable vascular scaffold,#13 intravascular ultrasound,#14 biodegradable ***:The findings based on the bibliometric studies provide the current status and trends in DES research and may help researchers to identify hot topics and explore new research directions in this field.

关键词： Drug-eluting stents Dual antiplatelet therapy Drug-coated balloon Bioresorbable scaffold Bibliometric

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