Pancreatic neuroendocrine neoplasms(pNENs)are rare and highly heterogeneous tumors originating from pluripotent stem cells with neuroendocrine differentiation in the pancreas,constituting approximately 3%of all pancre...
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Pancreatic neuroendocrine neoplasms(pNENs)are rare and highly heterogeneous tumors originating from pluripotent stem cells with neuroendocrine differentiation in the pancreas,constituting approximately 3%of all pancreatic tumors.^([1])The global incidence of pNENs has been increasing recently,and most cases are sporadic and more common in women.^([1,2])pNENs are clinically divided into functioning and nonfunctioning tumors depending on whether the tumors are accompanied by a clinical syndrome related to specific hormone overproduction.
Housing vacancy can reflect the destocking degree of the real estate *** on the data of 57 opened residential quarters(46,622 units)from 2015 to 2018,this paper constructs a calculation formula of the sales vacancy ra...
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Housing vacancy can reflect the destocking degree of the real estate *** on the data of 57 opened residential quarters(46,622 units)from 2015 to 2018,this paper constructs a calculation formula of the sales vacancy rate and then analyzes the spatial pattern in Guangzhou’s urban *** results show that there is obvious differentiation in the spatial pattern of housing sales vacancy in Guangzhou’s urban district,showing a higher spatial pattern in the old area and urban district and a lower spatial pattern in the core *** with high vacancy rates are mainly located in the east of the old area,the south and east of the urban district and near Baiyun Mountain in the north.
Erratum to Nano Research 2020,13(11):3110-3122 https://d0i.0rg/l 0.1007/s 12274-020-2981-8 The article Fluorescent glycan nanoparticle-based FACS assays for the identification of genuine drug-resistant cancer cells wi...
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Erratum to Nano Research 2020,13(11):3110-3122 https://d0i.0rg/l 0.1007/s 12274-020-2981-8 The article Fluorescent glycan nanoparticle-based FACS assays for the identification of genuine drug-resistant cancer cells with differentiation potential,written by Chenglong Wang et al.,was erroneously originally published electronically on the publishers internet portal(currently SpringerLink)on 10 August 2020 with the Acknowledgements.
Increased evidence shows that normal stem cells may contribute to cancer development and progression by acting as cancer-initiating cells through their interactions with abnormal environmental *** postulate that norma...
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Increased evidence shows that normal stem cells may contribute to cancer development and progression by acting as cancer-initiating cells through their interactions with abnormal environmental *** postulate that normal stem cells and cancer stem cells (CSC) possess similar mechanisms of self-renewal and *** can be the key to the elaboration of anti-cancer-based *** this article,we focus on a controversial new theme relating to *** may have a critical stage characterized as a "therapeutic window",which can be identified by asso-ciation of molecular,biochemical and biological *** such a stage can allow the production of more effective therapies (*** stem cells) to treat several *** importantly,confirming the existence of a similar therapeutic window during the conversion of normal stem cells to malignant CSC may lead to targeted therapy specifically against *** conversion information may be derived from investigating the biological behaviour of both normal stem cells and cancerous stem ***,there is little knowledge about the cellular and molecular mechanisms that govern the initiation and maintenance of *** on co-evolution and interdependence of cancer with normal tissues may lead to a useful treatment paradigm of *** crosstalk between normal stem cells and cancer formation may converge developmental stages of different types of stem cells (*** stem cells,CSC and embryonic stem cells).The differential studies of the convergence may result in novel therapies for treating cancers.
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