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A novel flexible nerve guidance conduit promotes nerve regeneration while providing excellent mechanical properties

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Neural Regeneration Research 2025年第7期20卷 2084-2094页

作者： Tong Li Quhan Cheng Jingai Zhang Boxin Liu Yu Shi Haoxue Wang Lijie Huang Su Zhang Ruixin Zhang Song Wang Guangxu Lu Peifu Tang Zhongyang Liu Kai Wang Department of Orthopedics the Fourth Medical Center of Chinese PLA General HospitalBeijingChina Department of Training and Sports Medicine Characteristic Medical Center of Chinese People’s Armed Police ForceTianjinChina Medical School of Chinese PLA BeijingChina Key Laboratory of Bioactive Materials for the Ministry of Education College of Life SciencesNankai UniversityTianjinChina Department of Orthopedics Tianjin HospitalTianjinChina Department of Rehabilitation Medicine Er Quan Hospital of PAPWuxiJiangsu ProvinceChina

Autografting is the gold standard for surgical repair of nerve defects>5 mm in length;however,autografting is associated with potential complications at the nerve donor *** an alternative,nerve guidance conduits may be *** ideal conduit should be flexible,resistant to kinks and lumen collapse,and provide physical cues to guide nerve *** designed a novel flexible conduit using electrospinning technology to create fibers on the innermost surface of the nerve guidance conduit and employed melt spinning to align ***,we prepared disordered electrospun fibers outside the aligned fibers and helical melt-spun fibers on the outer wall of the electrospun fiber *** presence of aligned fibers on the inner surface can promote the extension of nerve cells along the *** helical melt-spun fibers on the outer surface can enhance resistance to kinking and compression and provide *** novel conduit promoted nerve regeneration and functional recovery in a rat sciatic nerve defect model,suggesting that it has potential for clinical use in human nerve injuries.

关键词： aligned fibers anti-kinking helical fibers nerve guidance conduit nerve regeneration peripheral nerve injury topological guidance

Three-dimensional time-varying sliding mode guidance law against maneuvering targets with terminal angle constraint

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Chinese Journal of Aeronautics 2022年第4期35卷 303-319页

作者： Xinxin WANG Hongqian LU Xianlin HUANG Yefeng YANG Zongyu ZUO center for Control Theory and guidance Technology Harbin Institute of TechnologyHarbin 150001China The Seventh Research Division Beihang UniversityBeijing 100191China

This paper deals with the problem of intercepting maneuvering targets with terminal angle constraints for missiles subjected to three-dimensional non-decoupling engagement *** achieve the finite-time interception and satisfactory overload characteristics, a time varying sliding mode control methodology is developed based on a time base generator function. The main feature of the proposed guidance law guarantees the Line-of-Sight(LOS) angles to converge to small neighborhoods of the desired values at the interception time. First, a fractional power extended state observer is used to estimate the unknown target acceleration, which can significantly reduce the adaptive switching gain. The fractional power extended state observer enjoys the advantage of better noise tolerance. Then, a newly designed sliding mode surface is constructed by introducing a time base generator function and the time-varying sliding mode guidance law is developed based on this time-varying sliding surface. The proposed guidance law significantly reduces the overload magnitudes. Numerical simulations are carried out to verify the performance of the proposed guidance law.

关键词： guidance law Maneuvering target Terminal angle constraint Three-dimensional Time-varying sliding mode

Identification of Molecular Markers for a Aphid Resistance Gene in Sorghum and Selective Efficiency Using These Markers

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Journal of Integrative Agriculture 2012年第7期11卷 1086-1092页

作者： CHANG Jin-hua CUI Jiang-hui XUE Wei ZHANG Qing-wen College of Agriculture and Biotechnology China Agricultural University Beijing 100096 P.R.China College of Agriculture Agricultural University ofHebei Baoding 071001 P.R.China Student employment guidance center Baoding Vocational and Technical College Baoding 071001 P.R.China

In this study, an F2 segregated population obtained by hybridization between the aphid-sensitive sorghum strain Qiansan and aphid-resistant cultivar Henong 16 was used to establish an aphid-resistant pool and an aphid-sensitive pool. 192 pairs of AFLP （amplified fragment length polymorphism） marker primers were screened in these pools using BSA （bulked segregant analysis）. Three pairs of EcoR I-CTG/Mse I-CCT, EcoR I-CTG/Mse I-CAT, and EcoR I-AGT/Mse I-CCC showed linkage with aphis resistance. EcoR I-CTG/Mse I-CCT-475, EcoR I-CTG/Mse I-CAT-390, and EcoR I-AGT/Mse I-CCC- 350 （E42/M52-350） were mapped within 6, 10, and 13 cM distances with the aphid-resistant gene by using Mapmaker 3.0 software. The bands amplified by EcoR I-CTG/Mse I-CCT-475 and EcoR I-CTG/Mse I-CAT-390 were extracted, cloned, and sequenced. Specific primers of SCAR （sequence characterized amplified regions） were then designed from these bands. A specific band of 300 bp was amplified by a pair of SCAR primers designed based on the sequence obtained from the EcoR I-CTG/Mse I-CAT-390 marker. The SCAR marker was named SCAS0. The marker was used to detect the F2, BC1, and F2：3 populations. The selective efficiency was 86.8, 91.1, and 86.3% in the BC1, F2, and F2：3 populations, respectively. The average selective efficiency was 88.2%.

关键词： sorghum bicolor aphid resistance gene molecular marker SCAR molecular assistant selection

Phosphate removal from domestic wastewater using thermally modified steel slag

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Journal of Environmental Sciences 2015年第5期27卷 81-88页

作者： Jian Yu Wenyan Liang Li Wang Feizhen Li Yuanlong Zou Haidong Wang College of Environmental Science and Engineering Beijing Forestry University National center for Rural Water Supply Technical guidance Chinese Center for Disease Control and Prevention Central Research Institute of Building and Construction Co. Ltd.MCC

This study was performed to investigate the removal of phosphate from domestic wastewater using a modified steel slag as the adsorbent. The adsorption effects of alkalinity, salt, water,and thermal modification were investigated. The results showed that thermal activation at 800℃ for 1 hr was the optimum operation to improve the adsorption capacity. The adsorption process of the thermally modified slag was well described by the Elovich kinetic model and the Langmuir isotherm model. The maximum adsorption capacity calculated from the Langmuir model reached 13.62 mg/g. Scanning electron microscopy indicated that the surface of the modified slag was cracked and that the texture became loose after heating. The surface area and pore volume did not change after thermal modification. In the treatment of domestic wastewater, the modified slag bed（35.5 kg） removed phosphate effectively and operated for 158 days until the effluent P rose above the limit concentration of 0.5 mg/L. The phosphate fractionation method, which is often applied in soil research, was used to analyze the phosphate adsorption behavior in the slag bed. The analysis revealed that the total contents of various Ca-P forms accounted for 81.4%-91.1%, i.e., Ca10-P 50.6%-65.1%, Ca8-P 17.8%-25.0%,and Ca2-P 4.66%-9.20%. The forms of Al-P, Fe-P, and O-P accounted for only 8.9%-18.6%. The formation of Ca10-P precipitates was considered to be the main mechanism of phosphate removal in the thermally modified slag bed.

关键词： Steel slag Thermal modification Phosphate Adsorption Fractionation

Coupled Dynamics and Integrated Control for Position and Attitude Motions of Spacecraft:A Survey

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IEEE/CAA Journal of Automatica Sinica 2023年第12期10卷 2187-2208页

作者： Feng Zhang Guangren Duan the Research and Development center China Academy of Launch Vehicle TechnologyBeijing 100076China IEEE the center for Control Science and Technology Southern University of Science and TechnologyShenzhen 518055 the center for Control Theory and guidance Technology Harbin Institute of TechnologyHarbin 150001China

Inspired by the integrated guidance and control design for endo-atmospheric aircraft,the integrated position and attitude control of spacecraft has attracted increasing attention and gradually induced a wide variety of study results in last over two decades,fully incorporating control requirements and actuator characteristics of space *** paper presents a novel and comprehensive survey to the coupled position and attitude motions of spacecraft from the perspective of dynamics and *** this end,a systematic analysis is firstly conducted in details to show the position and attitude mutual couplings of ***,in terms of the time discrepancy between spacecraft position and attitude motions,space missions can be categorized into two types:space proximity operation and space orbital *** on this classification,the studies on the coupled dynamic modeling and the integrated control design for position and attitude motions of spacecraft are sequentially summarized and *** the one hand,various coupled position and dynamic formulations of spacecraft based on various mathematical tools are reviewed and compared from five aspects,including mission applicability,modeling simplicity,physical clearance,information matching and *** the other hand,the development of the integrated position and attitude control of spacecraft is analyzed for two space missions,and especially,five distinctive development trends are captured for space operation ***,insightful prospects on future development of the integrated position and attitude control technology of spacecraft are proposed,pointing out current primary technical issues and possible feasible solutions.

关键词： Coupled position and attitude dynamic modeling integrated position and attitude control position and attitude coupling analysis spacecraft space missions

Redetermination of the Depositional Age of the Haerdaban Group in the Northern Margin of the Yili Block,Western Tianshan,NW China:Implications for Regional Tectonics and Pb-Zn Mineralization

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Acta Geologica Sinica(English Edition) 2023年第2期97卷 404-417页

作者： WANG Jialin GU Xuexiang XU Jingchi ZHANG Yongmei PENG Yiwei LU Liangtao State Key Laboratory of Processes and Mineral Resources China University of Geosciences(Beijing)Beijing 100083China School of Earth Sciences and Resources China University of Geosciences(Beijing)Beijing 100083China Development Research center of the China Geological Survey Beijing 100037China Mineral Exploration Technical guidance center of the Ministry of Natural Resources Beijing 100083China State Key Laboratory of Tectonic Controls on Mineralization and Hydrocarbon Accumulation of the Ministry of Natural Resources Chengdu University of TechnologyChengdu 610059China

The Yili Block in the Western Tianshan orogen is a key area for understanding the early crustal formation and evolution of the Central Asian orogenic belt,due to the widely-distributed Precambrian ***,it hosts a lot of medium–to large-scale sedimentary exhalative(SEDEX)Pb-Zn deposits that mainly occur in Proterozoic metamorphosed clasticcarbonate *** this study,LA-ICP-MS U-Pb analyses were carried out on detrital zircons in siltstones of the Precambrian Haerdaban Group in the Haerdaban Pb-Zn deposit and magmatic zircons in the diorite dyke that cuts through the strata and *** maximum depositional age of the siltstones was determined to be about 604 Ma,the diorite having formed at approximately 500 *** such,the Haerdaban Group was most likely formed in the Neoproterozoic Sinian,rather than the previously considered Mesoproterozoic *** materials of the Haerdaban Group were mostly derived from the Nanhua–Sinian mafic dykes and granitic rocks around Lake Sayram at the northern margin of the Yili *** is proposed that the Yili Block,together with the Kazakhstan and Central Tianshan blocks and the Tarim Craton,might all pertain to the same Rodinia supercontinent,which has great potential for targeting large to super-large SEDEX Pb-Zn deposits.

关键词： Haerdaban Group zircon U-Pb dating SEDEX Pb-Zn mineralization Neoproterozoic Yili Block Western Tianshan

Exploration on the Order-orientated Cultivation of Engineering Master for Industry Oriented Demand

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International Journal of Technology Management 2016年第5期 75-78页

作者： Liu xiaoguang Zhang yajing College of Electronic and Information Engineering Hebei University Innovative entrepreneurship guidance center Hebei University

full-time Master of engineering education has developed rapidly in recent years, but in the talent cultivation, professional degree of master of engineering characteristics is not obvious, there are such problems as backward curriculum system, practice teaching is weak, tutor guidance effectiveness is not high, thesis and practice related to small. Colleges and universities need to further adjust and optimize the master of engineering training mode and promote the cooperation between colleges and enterprises, the order-form talent-training model as a handle, promote the depth of integration of production, study and research, and highlight the characteristics of talent cultivation.

关键词： Master of engineering Order-orientated Cultivation training mode

Stability analysis and controller design of T-S fuzzy systems with time-delay under imperfect premise matching

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Journal of beijing Institute of Technology 2012年第3期21卷 387-393页

作者：张泽健黄显林班晓军高晓智 center for Control Theory and guidance Technology Harbin Institute of Technology Department of Automation and Systems Technology Aalto University

The issue of the stability and controller design of Takagi-Sugeno（T-S） fuzzy control systems with time-delay is investigated under imperfect premise matching when the T-S fuzzy time-delay model and fuzzy controller do not share the same membership functions.A new stability criterion which contains the information of membership functions is *** new stability criterion is less conservative,and enhances the design *** numerical examples are presented to illustrate the conservativeness and effectiveness of the proposed method.

关键词： T-S fuzzy model time-delay system stability analysis imperfect premise matching linear matrix inequality

Three-Dimensional Normal Stress for Controlling Electronic Structure and Magnetic Property of Fe2Ge

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Journal of Harbin Institute of Technology(New Series) 2018年第6期25卷 90-96页

作者： Weifu Cen Lin Lyu Yinye Yang Meihui Fan guidance center of Undergraduate Innovation and entrepreneurship Guizhou Minzu University Guiyang 550025 China Special and Key Laboratory of Guizhou Provincial Higher Education for Photoelectronic Information Processing and Analysis Guizhou Minzu University Guiyang 550025 China

A system study of the three-dimensional normal stress for regulating electronic structure and magnetic property of Fe_2Ge is studied. The density states of Fe more than 92% contribution come from Fe 3d,the density states of Ge mainly contributed from Ge 4p and Ge 4s,and the Fe 3d spin induces the Ge 4p electron transfer. The inductive effect increases germanium electron energy,weakens the Fe spin density of states,opposes the stability of the ferromagnetic state. The magnetic moment varies from 5 to 3 μB with the stress charges from-30 to 30 GPa. The charge of Fe is negative whereas the Ge atom is positively charged,the Fe atom loses charge,the charge transfers to the Ge atom. The unevenly distributed charge forms the newoccupy state and spin polarization state in the Fe_2Ge electron structure system. The Fe is the electron donor,the total electron is transferred to Ge,but the total numbers of gain electron and total numbers of lost electron are not equal,so the Fe_2Ge electron system may have hybridization between the Fe 3d state and Ge 4p *** magnetic of Fe_2Ge mainly comes from the unoccupied Fe 3d orbital,the Fe 3d is positive spinpolarization state and the spin-polarization strength is decreased,the Ge 4p is negative spin-polarization state and the spin-polarization strength are increased. M oreover,electrons-spin polarization is relevant to the structure parameters of the Fe_2Ge system,and controls spin-polarized electronic behavior by means of adjusting ferromagnetic.

关键词： Fe Ge electronic structure magnetic property stress controlling first-principles