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The burden and psychosocial impact on immediate caregivers of patients with spinal cord injury in a tertiary health facility,Edo State,Nigeria

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Journal of Integrative nursing 2024年第2期6卷 103-110页

作者： Timothy Aghoghko EHWARIEME Uzezi JOSIAH Auwuli EMINA department of nursing Science School of Basic Medical SciencesUniversity of BeninBenin CityEdo StateNigeria department of nursing Science Delta State University AbrakaDelta StateNigeria department of nursing Science Faculty of Basic Medical and Health SciencesBenson Idahosa UniversityBenin CityEdo StateNigeria

Objective:This study aimed to assess the burden and psychosocial impact of spinal cord injury on the immediate caregivers at a tertiary health facility in Benin City,Edo *** and Methods:A descriptive cross-sectional survey design was adopted among 73 family caregivers in the neurological ward of a tertiary health facility using a structured questionnaire as instrument of data *** collected were analyzed using descriptive statistics and multiple logistic ***:Findings revealed that an overall mean of 2.73 indicates that the burden on the caregivers was moderate with a moderate psychological impact(m=2.88)and a high sociological impact(m=3.12).Factors affecting the caregiving provided by immediate caregivers include social and household responsibilities(94.5%),financial situation(89.0%),family support(83.6%),and health status of the caregiver(80.8%).Age(odds ratio[OR]=5.67,95%confidence interval[CI]:1.23-27.17,P=0.027),education(OR=3.75,95%CI:1.05-13.39,P=0.041),and“others”(spouses,siblings,friends,or extended family members)(OR=3.167,95%CI:1.583-6.337,P=0.001)were predictors for high psychological impact while education(OR=0.074;95%CI:0.015-0.370,P=0.001)and caregiving role(OR=3.167;95%CI:0.1.583-6.337,P=0.001)high sociological ***:Majority of the caregivers experience moderate burden,moderate psychological impact,and high sociological *** these factors is essential for developing targeted interventions and support services to address the unique needs of caregivers and mitigate the burden of caregiving on their psychosocial health.

关键词： Burden caregivers predictors of psychosocial impact psychological impact sociological impact spinal cord injury

nursing student volunteers and their level of involvement during the COVID-19 pandemic:a systematic review

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Frontiers of nursing 2024年第1期11卷 23-37页

作者： Yayu Nidaul Fithriyyah Syahirul Alim department of Medical Surgical-nursing Faculty of MedicinePublic Health and NursingUniversitas Gadjah MadaYogyakarta 55281Indonesia department of basic&Emergency nursing Faculty of MedicinePublic Health and NursingUniversitas Gadjah MadaYogyakarta 55281Indonesia

Objective:Many strategic efforts were made to address nurses'shortage in controlling Coronavirus disease 2019(COVID-19),including recruiting student health *** review aimed to explore the contribution and involvement of nursing student volunteers during ***:A systematic review was registered in PROSPERO International *** databases for ar ticle search included:SCOPUS,EBSCO MEDLINE,Pub Med,Pro Quest,Springer,Sage Pub,and hand *** critical appraisal study quality using The Joanna Briggs *** extraction and synthesis used Population,Intervention,Comparison,Outcome,and Design(PICO and D)framework with thematic ***:Twelve studies were enrolled from 2545 retrieved,with 4 synthesized themes:(1)determinant of the involvement of nursing student volunteers during COVID-19,which includes 3 subthemes:motivations,perception,and barriers,(2)expectations and actual condition of nursing students as volunteers,(3)the need for nursing student volunteers,and(4)the impact and level of student volunteers'*** student volunteers contribute to providing direct or indirect services to ***:This review provides an overview of nursing student volunteers'needs useful in developing competency frameworks and the role of culturally sensitive volunteers in education and *** the future,student volunteers could choose the appropriate volunteer program and location according to their competence.

关键词： COVID-19 nursing students systematic review volunteers

Effect of Eu3+,Bi3+,and Li+ doping on luminescent property of GdNbO4

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Journal of Rare Earths 2024年第1期42卷 66-75页

作者： S.W.Wi Y.S.Lee department of Physics and Integrative Institute of basic Sciences Soongsil University

We investigated the emission properties of Eu3+-doped GdNbO4-based oxide phosphors,aiming at improving the Eu3+emission by codoping of Bi3+and Li+.Eu3+singly doped,Eu3+and Bi3+doubly doped,and Eu3+,Bi3+,and Li+triply doped GdNbO4were prepared using a high-temperature solid-state reaction *** red-orange emissions from Eu3+in the singly doped samples are significantly improved by the codoping of Bi3+,mainly due to the energy transfer from Bi3+to Eu3+.The additional codoping of Li+is found to increase the Eu3+emission *** improvement might be attributed to the increase in the photoluminescent quantum yield originating from larger grain sizes and better crystallinity.A detailed analysis of the X-ray diffraction pattern and the asymmetric ratio estimated from the photoluminescence spectra show that the local lattice environment around Eu3+in GdNbO4does not change significantly with the codoping of Bi3+and Li+.Our results indicate that Li+doping is a promising way to improve the emission properties of rare-earth ion-doped GdNbO4phosphors.

关键词： Eu 3+ GdNbO 4 Codoping of Li + Photoluminescence Sensitizer Rare earths

Nicotine up-regulates SLC7A5 expression depending on TRIM29 in non-small cell lung cancer

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Genes & Diseases 2024年第2期11卷 582-584页

作者： Dahua Liu Haolin Ren Guimin Wen Pu Xia Biological Anthropology Institute College of Basic Medical ScienceJinzhou Medical UniversityJinzhouLiaoning 121000China department of Radiology The First Affiliated Hospital of Dalian Medical UniversityDalianLiaoning 116011China department of Community nursing College of NursingJinzhou Medical UniversityJinzhouLiaoning 121000China

Non-small cell lung cancer(NSCLC)is a malignant tumor that poses a serious threat to human ***(LUAD)and squamous cell carcinoma(LUSC)are two common types of *** originate from glandular and squamous cells of the bronchial epithelium,*** gene changes during tumorigenesis is conducive to the selection of suitable treatment methods for ***98 is a heterodimeric transmembrane glycoprotein,which is composed of a heavy chain and a light chain.1 cD98 heavy chain(CD98hc),also known as 4F2hc or SLC3A2,is an 85kDa type ll transmembraneglycoprotein,which consists of a cytoplasmic region(NH2 terminal),a single chain transmembrane region,and a huge extracellular region(COOH terminal).1 CD98hc can combine with the CD98 light chain,LAT1(SLC7A5),to form CD98 protein through disulfide bonds.1 SLC7A5 is a 12 times transmembrane helix bundle protein composed of 501-535 amino acid residues1.

关键词： lung cancer NSCLC

Engineering the spectra of photon triplets generated from micro/nanofiber

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Chinese Physics B 2024年第3期33卷 408-414页

作者：瞿川郭东琴李笑笑刘振旗赵义张胜海卫正统 The College of basic department Information Engineering UniversityZhengzhou 450000China

Quantum light sources are the core resources for photonics-based quantum information *** investigate the spectral engineering of photon triplets generated by third-order spontaneous parametric down-conversion in micro/*** phase mismatching at one-third pump frequency gives rise to non-degenerate photon triplets,the joint spectral intensity of which has an elliptical locus with a fixed eccentricity of√6/***,we propose a frequency-division scheme to separate non-degenerate photon triplets into three channels with high heralding efficiency for the first *** an appropriate pump wavelength can compensate for the fabrication errors of micro/nanofiber and also generate narrowband,non-degenerate photon triplet sources with a high signal-to-noise ***,the long-period micro/nanofiber grating introduces a new controllable degree of freedom to tailor phase matching,resulting from the periodic oscillation of *** this scheme,the wavelength of photon triplets can be flexibly tuned using quasi-phase *** study the generation of photon triplets from this novel perspective of spectrum engineering,and we believe that this work will accelerate the practical implementation of photon triplets in quantum information processing.

关键词： photon triplets micro/nanofiber spectrum engineering

Higgs-like(pseudo)scalars in AdS_(4),marginal and irrelevant deformations in CFT_(3),and instantons on S^(3)

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Chinese Physics C 2024年第4期48卷 68-81页

作者： M.Naghdi department of Physics Faculty of Basic SciencesUniversity of IlamIlamIran

Employing a 4-form ansatz of 11-dimensional supergravity over a non-dynamical AdS_(4)×S^(7)/Z_(k)background and setting the internal space as an S1 Hopf fibration on CP3,we obtain a consistent ***(pseudo)scalars,in the resulting scalar equations in Euclidean AdS_(4)space,may be considered to arise from(anti)M-branes wrapping around the internal directions in the(Wick-rotated)skew-whiffed M2-brane background(as the resulting theory is for anti-M2-branes),thus realizing the modes after swapping the three fundamental representations 8_(s),8_(c),and 8_(v) of SO(8).Taking the backreaction on the external and internal spaces,we obtain the massless and massive modes,corresponding to exactly marginal and marginally irrelevant deformations on the boundary CFT3,***,we obtain a closed solution for the bulk equation and compute its correction with respect to the background ***,considering the Higgs-like(breathing)mode m^(2)=18,having all supersymmetries as well as parity and scale-invariance broken,solving the associated bulk equation with mathematical methods,specifically the Adomian decomposition method,and analyzing the behavior near the boundary of the solutions,we realize the boundary duals in the SU(4)×U(1)-singlet sectors of the ABJM ***,introducing the new dual deformationΔ_(+)=3,6 operators made of bi-fundamental scalars,fermions,and U(1)gauge fields,we obtain the SO(4)-invariant solutions as small instantons on a three-sphere with the radius at infinity,which correspond to collapsing bulk bubbles leading to big-crunch singularities.

关键词： AdS_(4)/CFT_(3)correspondence scalar equations in AdS_(4) instantons marginal and irrelevant operators (anti)M-branes

Association of spiritual well-being with quality of life among undergraduate nursing students

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Journal of Integrative nursing 2024年第1期6卷 49-54页

作者： Ahmad SHAHID Hina HUSSAIN Nazia SHUAIB Ahmad RASOOL Fatima YOUNIS Zoya NASAB department of nursing Professional College of Nursing and Health SciencesIslamabadPakistan department of nursing Rawal Institute of Health SciencesIslamabadPakistan department of nursing Rawal College of NursingIslamabadPakistan School of nursing and Health Zhengzhou UniversityZhengzhouChina

Objective:The study was conducted with the aim of determining the spiritual well-being(SWB)of nursing students and its association with quality of life(QOL).Materials and Methods:A cross-sectional analytical study was conducted with a sample size of 504 nursing students collected from January 2023 to March 2023 in the nursing institutes of Khyber Pakhtunkhwa,Pakistan,using convenient sampling techniques.A Spiritual Health and Life-Orientation Measure(SHALOM)questionnaire for SWB and K-27 QOL(K-27 QOL)instrument were used for data collection that contains three ***:The number of female participants was in the majority(50.4%)compared to male nurses(49.6%).The overall mean score of SWB of the students was 3.79±0.48,while the mean K-27 QOL score was 3.73±*** were significant differences between the groups of gender(P=0.001),while no significant difference within the groups of semester(P=0.061)and college status(0.285).In QOL,there were significant differences within the groups of semester(P=0.000)and college status(P=0.036)while no significant difference in gender category(P=0.480).SHALOM score is positively and moderately correlated with QOL score(r=0.597,P<0.05).Conclusion:Spiritual practices are one of the important factors that are associated positively with QOL,therefore to enhance the QOL,it will require spiritual practices.

关键词： nursing education nursing student quality of life spiritual nursing care spirituality well‑being

Evaluating the influence of a structured nursing protocol on targeted outcomes in rheumatoid arthritis patients

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Journal of Integrative nursing 2024年第1期6卷 22-28页

作者： Mohammed Elsayed ZAKY Shimaa Magdi FARGHALY Osama Mohamed Elsayed RAMADAN Rehab M.ABDELKADER Mostafa SHABAN department of Medical Surgical nursing Faculty of Nursing Cairo UniversityCairoEgypt department of Medical Surgical nursing College of NursingJouf UniversitySakakaAljawfSaudi Arabia Faculty of nursing Cairo University CairoEgypt department of Geriatric nursing Faculty of Nursing Cairo UniversityCairoEgypt

Objective:Rheumatoid arthritis(RA)requires comprehensive *** nursing protocols may enhance outcomes,but evidence is *** study evaluated the effect of a structured nursing protocol on RA *** and Methods:In this one-group pre-post study,30 Egyptian RA patients completed assessments before and after a 12-week nursing protocol comprising education,psychosocial support,and self-management *** included clinical evaluation of joint counts,erythrocyte sedimentation rate(ESR),and C-reactive protein(CRP)and patient-reported Arthritis Self-Efficacy Scale(ASES),Health Assessment Questionnaire(HAQ),Visual Analog Scale(VAS)for pain,and Hospital Anxiety and Depression Scale(HADS).Results:The study demonstrated significant improvements in both clinical-and patient-reported *** count decreased from 18.4±4.2 to 14.2±3.8(Pnursing protocol significantly improved clinical disease activity,physical functioning,pain,self-efficacy,and emotional well-being in RA patients.A multifaceted nursing intervention appears beneficial for optimizing RA outcomes.

关键词： nursing care patient education quality of life rheumatoid arthritis self‑management

MicroRNAs:A novel signature in the metastasis of esophageal squamous cell carcinoma

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World Journal of Gastroenterology 2024年第11期30卷 1497-1523页

作者： Qi-Ying Wei Feng Jin Zhong-Yu Wang Bing-Jie Li Wen-Bo Cao Zhi-Yan Sun Sai-Jun Mo department of Pathophysiology School of Basic Medical SciencesZhengzhou UniversityZhengzhou 450001Henan ProvinceChina department of Perioperative Medicine The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052Henan ProvinceChina Division of Special Service Department of Basic OncologySchool of Basic MedicineZhengzhou UniversityZhengzhou 450001Henan ProvinceChina department of basic Science of Oncology School of Basic Medical SciencesZhengzhou UniversityZhengzhou 450001Henan ProvinceChina

Esophageal squamous cell carcinoma(ESCC)is a malignant epithelial tumor,characterized by squamous cell differentiation,it is the sixth leading cause of cancer-related deaths *** increased mortality rate of ESCC patients is predominantly due to the advanced stage of the disease when discovered,coupled with higher risk of metastasis,which is an exceedingly malignant charac-teristic of cancer,frequently leading to a high mortality ***,there is currently no specific and effective marker to predict and treat metastasis in ***(miRNAs)are a class of small non-coding RNA molecules,approximately 22 nucleotides in *** are vital in modulating gene expression and serve pivotal regulatory roles in the occurrence,progression,and prognosis of ***,we have examined the literature to highlight the intimate correlations between miRNAs and ESCC metastasis,and show that ESCC metastasis is predominantly regulated or regulated by genetic and epigenetic *** review proposes a potential role for miRNAs as diagnostic and therapeutic biomarkers for metastasis in ESCC metastasis,with the ultimate aim of reducing the mortality rate among patients with ESCC.

关键词： MicroRNAs Esophageal squamous cell carcinoma Metastasis Signaling pathway Epigenetics mechanism