检索结果-南通市图书馆

Family Medicine and Community Health 2023年第4期11卷 4-12页

作者： Juliane Regina Framme Su-Jong Kim-Dorner Bettina Heidtmann Thomas Michael Kapellen Karin Lange Olga Kordonouri Heike Saßmann Medical Psychology Hannover Medical SchoolHannoverGermany Paediatric Endocrinology and Diabetology Catholic Childrens Hospital WilhelmstiftHamburgGermany Hospital for Children and Adolescents University of Leipzig Medical CenterLeipzigGermany Department of Paediatrics MEDIAN Children's Hospital"Am Nicolausholz"Bad KösenGermany Diabetes Center for Children and Adolescents Auf der Bult Children's HospitalHannoverGermany

Objective The COVID-19 pandemic had an impact on everyday life and in general,reduced the health-related quality of life(HRQoL)of *** this study,we assess the HRQoL of adolescents with type 1 diabetes(T1D)in Germany since the second wave of the COVID-19 pandemic by using self-report and parent-proxy reports,to identify risk factors,to compare to peers and to examine the agreement of HRQoL between parents and their *** A total of 445 adolescents(12–18 years)and 413 parents participated in an anonymous cross-sectional survey conducted at three German diabetes centres from January 2021 to June *** criteria were diabetes duration≥1year and *** HRQoL was assessed by using self-report and parent-proxy report versions of the KIDSCREEN-10 *** The majority of adolescents reported average(75.5%)*** 11.3%of teens reported high and 13.2%low ***’s female gender,older age,higher diabetes burden and parental depression symptoms contributed to lower self-reported HRQoL among *** parent-proxy reports,increasing diabetes burdens,parental depression symptoms,non-migrant status,high education and ketoacidosis contributed to lower scores on teen *** mean scores of the KIDSCREEN-10 index for adolescents did not differ from the German *** comparison to healthy peers during the first wave of the pandemic,adolescents in the current study reported higher *** overall teen-parent agreement was fair although parents reported significantly lower teen HRQoL than adolescents *** HRQoL of most adolescents with T1D during the COVID-19 pandemic was average with parents reporting significantly lower ***-reported and parent-proxy-reported HRQoL and the level of agreement due to different perspectives can provide important information for clinical care and intervention planning.

关键词： adolescent wave life

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

耐药性房颤射频导管消融治疗后出现明显肺静脉狭窄的患者静息及运动时的肺血流动力学

引用

世界核心医学期刊文摘(心脏病学分册) 2006年第2期 48-49页

作者： Arentz T Weber R. Jander N. 杜媛 Abteilung Rhythmologie Herz- Zentrum Sü dring 15 79188 bad Krozingen Germany

Aims: Iatrogenic pulmonary vein(PV) stenosis after radiofrequency catheter ablation for atrial fibrillation(AF) is a new pathology in cardiology. The effects of PV stenosis on the pulmonary circulation are not yet known. We provide long-term follow-up datain patients with significant PV stenosis including magnetic resonance imaging(MRI) and Swan Ganz(SG) right heart *** and results: One hundred and seventeen patients had MRI 12-24 months after the AF ablation procedure. Eleven patients(58± 7 years, nine males) with significant stenosis(n=9) or occlusion of the proximal PV(n=5) at this follow-up were re-examined using MRI and SG right heart catheterization at rest and during exercise(follow-up time since PV ablation 50± 15 months). None of these underwent previous PV angioplasty. When compared with prior MRI studies, no significant changes were noted. At rest, no patient had pulmonary hypertension. At 100W, seven patients had elevated pulmonary artery pressures, three of them probably caused, in part, by left ventricular dysfunction. Conclusion: Significant stenosis/occlusions of one or two PV do not create pulmonary hypertension at rest during long-term follow-up. However, seven of the 11 patients develop pulmonary hypertension during exercise. All three patients with stenosis/occlusions of two PV were affected.

关键词：射频导管消融肺动脉房颤心房纤颤静息患者

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Screening for 26 per-and polyfluoroalkyl substances(PFAS)in German drinking waters with support of residents

引用

Eco-Environment & Health 2023年第4期2卷 235-242页

作者： Vanessa Ingold Alexander Kämpfe Aki Sebastian Ruhl German Environment Agency Section II 3.3Schichauweg 5812307BerlinGermany German Environment Agency Section II 3.2Heinrich-Heine-Straße 1208645Bad ElsterGermany Technische Universität Berlin Chair of Water TreatmentKF4Straße des 17.Juni 13510623BerlinGermany

The occurrence of per-and polyfluoroalkyl substances(PFAS)in water cycles poses a challenge to drinking water quality and *** order to counteract the large knowledge gap regarding PFAS in German drinking water,89 drinking water samples from all over Germany were collected with the help of residents and were analyzed for 26 PFAS by high-performance liquid chromatography with tandem mass spectrometry(HPLC-MS/MS).The 20 PFAS recently regulated by sum concentration(PFAS_(∑20)),as well as six other PFAS,were quantified by targeted *** all drinking water samples,PFAS_(∑20 )was below the limit of 0.1μg/L,but the sum concentrations ranged widely from below the limit of quantification up to 80.2 ng/*** sum concentrations(PFASP4)of perfluorohexanesulfonate(PFHxS),perfluorooctanesulfonate(PFOS),perfluorooctanoate(PFOA),and perfluorononanoate of 20 ng/L were exceeded in two *** most frequently detected individual substances were PFOS(in 52%of the samples),perfluorobutanesulfonate(52%),perfluorohexanoate(PFHxA)(44%),perfluoropentanoate(43%)and PFHxS(35%).The highest single concentrations were 23.5 ng/L for PFHxS,15.3 ng/L for PFOS,and 10.1 ng/L for *** regionally elevated concentrations were identified,but some highly urbanized areas showed elevated *** of substitution PFAS,including 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoate and 2,2,3-trifluor-3-[1,1,2,2,3,3-hexafluor-3-(trifluormethoxy)propoxy]-propanoate(anion of ADONA),were very low compared to regulated *** most frequently detected PFAS were examined for co-occurrences,but no definite correlations could be found.

关键词： Persistent chemicals Organic micro-pollutants EU drinking water directive Indicator PFAS Drinking water

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

岩骨普通多维体层摄影在听神经瘤诊断中的价值

引用

放射学实践 1989年第1期4卷 9-15页

作者： Von S.Grehn 高起学 Radiologische Abteilung (Chefarzt PD Dr.med.Stefan Grehn)des Caritaskranken hauses bad Mergentheim 同济医科大学附属同济医院

在当今CT 和磁共振体层摄影的时代,普通的岩骨体层摄影对诊断这一区域的占位性病变仍具重要地位。

关键词：岩骨体层摄影听神经瘤 X线诊断

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

传统中医对椎间盘摘除术后疼痛综合征的治疗效果

传统中医对椎间盘摘除术后疼痛综合征的治疗效果

引用

国际传统医药大会

作者：孙卫中马文慧王建伟邑晓中 Arne Kapner 马卫东 German Center for TCM Ludwig-Thorna-Weg 21 94072 bad Füssing Germany German Center for TCM Ludwig-Thorna-Weg 21 94072 bad Füssing Germany German Center for TCM Ludwig-Thorna-Weg 21 94072 bad Füssing Germany German Center for TCM Ludwig-Thorna-Weg 21 94072 bad Füssing Germany German Center for TCM Ludwig-Thorna-Weg 21 94072 bad Füssing Germany German Center for TCM Ludwig-Thorna-Weg 21 94072 bad Füssing Germany

＜正＞bad Fus sing在德国中医堂和Diis seldorf的***医院中医中心用针灸和中医推拿等疗法。在3 年中对63名平均年龄58岁（男52．4％,女47．8％）的腰椎间盘摘除术（开放型,强直型,皮下型）后疼痛综合征病人进行了传统中医的治疗。

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Novel computer-assisted method for revision arthroplasty of the knee

引用

World Journal of Orthopedics 2015年第10期6卷 821-828页

作者： Hanns-Edgar Hoffart Harald Dinges Stefan Kolbeck Peter Ritschl Hagen Hommel Kreisklinik Jugenheim 64342 Seeheim-JugenheimGermany Westpfalz-Klinikum Standort II KuselOrtho-p?dische Klinik66869 KuselGermany HELIOS Klinik bad Gandersheim 37581 Bad GandersheimGermany Orthop?disches Krankenhaus Gersthof 1180 ViennaAustria Krankenhaus M?rkisches Oderland Betriebsteil Wriezen16269 WriezenGermany

AIM: To introduce the navigation system of software and instruments designed specifically for revision total knee arthroplasty(TKA).METHODS: We present an imageless navigation system for revision TKA,with optical point and tracker identification to assess kinematic and anatomical *** system automatically positions the cutting guides with a motorized cutting *** cutting unit is placed on the distal femur with a femoral clamp and acts as a rigid body and the base for all femoral *** surgical technique for using the navigation system for revision TKA is based on the technique used in primary ***,there are some important *** most notable are:(1) differences in estimation of the position of the primary implant relative to the bone and the mechanical axes;(2) the specific possibilities the revision navigation software offers in terms of optimal joint level positioning; and(3) the suggested "best fit" position,in which the clock position,stem position and offset,femoral component size,and mediolateral position of the femoral component are taken into account to find the optimal femoral component *** assessed the surgical technique,and accompanying software procedural steps,of the system,identifying any advantages or disadvantages that they ***: The system aims to visualize critical steps of the procedure and is intended as a tool to support the surgeon in surgical *** a computer-assisted cutting device with navigation makes it possible to carry out precise cuts without ***,the femoral clamp provides a stable fixation mechanism for the motorized cutting unit.A stable clamp is paramount in the presence of periarticular bony *** system allows the position of the primary implant relative to the bone and mechanical axes to be estimated,at which point any malalignments can be *** also offers an optimal joint level position for implantation,and suggests a "best fit" p

关键词： Knee Navigation system Revision total knee arthroplasty Computer-assisted surgery Surgical technique

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

肥胖对不稳定性心绞痛/非ST段抬高型心肌梗死患者死亡率的影响

引用

世界核心医学期刊文摘（心脏病学分册） 2007年第12期3卷 37-38页

作者： Buettner H.J. Mueller C. Gick M. 王亭忠 Interventional Cardiology Herz-Zentrum Sü dring 15 D-79189 Bad Krozingen Germany

目的:肥胖与糖尿病和严重冠状动脉疾病(CAD)相关。在非ST段抬高型急性冠状动脉综合征患者中,肥胖和预后之间的关系尚不清楚。本研究拟评估肥胖对采取早期血运重建的不稳定性心绞痛/非ST段抬高型心肌梗死(UA/NSTEMI)患者预后的影响。方... 详细信息

目的:肥胖与糖尿病和严重冠状动脉疾病(CAD)相关。在非ST段抬高型急性冠状动脉综合征患者中,肥胖和预后之间的关系尚不清楚。本研究拟评估肥胖对采取早期血运重建的不稳定性心绞痛/非ST段抬高型心肌梗死(UA/NSTEMI)患者预后的影响。方法和结果:在一项包括1676例连续UA/NSTEMI患者的前瞻性队列研究中,分析了肥胖与全因死亡率之间的关系。

关键词：不稳定性心绞痛患者 ST 死亡率

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Adsorption/Desorption of Low-density Lipoprotein on a Heparinized Surface of Gold Sensors

引用

Chemical Research in Chinese Universities 2012年第2期28卷 323-328页

作者： LAN Ping JI Jing HUANG Xiao-Jun GUDURU Deepak GROTH Thomas VIENKEN Jorg D1NG Hui College of Materials and Textiles Jiaxing UniversityJiaxing 314001P.R.China Key Laboratory of Macromolecular Synthesis and Functionalization Ministry of EducationDepartment of Polymer Science and EngineeringZhejiang UniversityHangzhou 310027P.R.China Biomedical Materials Group Department of Pharmaceutics and BiopharmaeeuticsInstitute of PharmacyMartin Luther University Halle-WittenbergHalle(Saale)06120Germany Fresenius Medical Care of Deutschland GmbH BioSciences DepartmentBad Homburg 61352Germany College of Mathematics Physics and Information Engineering Jiaxing UniversityJiaxing 314001P.R.China

Heparin has been considered to be a potentially useful ligand for low-density lipoprotein（LDL） detection and analysis in a clinical *** order to construct an affinity surface for preferential adsorption of LDL,heparin-modified gold surface（GS-Hep） was fabricated by a self-assembling method and hydrophobic-modified gold surfaces（GS-Hydro） was used as a *** morphologies of the modified gold surfaces were investigated by atomic force microscopy（AFM） and the quantity of heparin bound to gold surface was assayed by the toluidine blue（TB） colorimetric *** contact angles were determined to investigate wettability on GS-Hep and *** plasmon resonance（SPR） technique was used subsequently to detect the selective binding of LDL with *** the investigation on the effect of pH on LDL adsorption suggests that lower pH lead to higher quantities of LDL adsorption on *** with GS-Hydro,GS-Hep is selective for LDL from both single and binary protein ***,adsorbed LDL on GS-Hep could be washed off by injecting elution solution,such as NaCl solution,for the purpose of the regeneration of GS-Hep for further LDL adsorption.

关键词： Adsorption/desorption Low-density lipoprotein(LDL) Heparinized surface Surface plasmon resonance

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Sorafenib delivery nanoplatform based on superpara- magnetic iron oxide nanoparticles magnetically targets hepatocellular carcinoma

引用

Nano Research 2017年第7期10卷 2431-2448页

作者： Nicoletta Depalo Rosa Maria lacobazzi Gianpiero Valente Ilaria Arduino Silvia Villa Fabio Canepa Valentino Laquintana Elisabetta Fanizza Marinella Striccoli Annalisa Cutrignelli Angela Lopedota Letizia Porcelli Amalia Azzariti Massimo Franco Maria Lucia Curri Nunzio Denora Istituto per i Processi Chimico-Fisici-CNR UOS Bari Via Orabona 4 70125 Bari Italy Istituto Tumori IRCCS Giovanni Paolo II viale O. Flacco 65 70124 Bari Italy Dipartimento di Chimica Universita degli Studi di Bad Aldo Moro Via Orabona70125 Bari Italy Dipartimento di Farmacia-Scienze del Farmaco Universita degli Studi di Bari Aldo Moro Via Orabona 4 70125 Bari Italy Dipartimento di Chimica e Chimica Industriale Universita di Genova Via Dodecaneso 31 16146 Genova Italy

Currently, sorafenib is the only systemic therapy capable of increasing overall survival of hepatocellular carcinoma patients. Unfortunately, its side effects, particularly its overall toxicity, limit the therapeutic response that can be achieved. Superparamagnetic iron oxide nanoparticles （SPIONs） are very attractive for drug delivery because they can be targeted to specific sites in the body through application of a magnetic field, thus improving intratumoral accumulation and reducing adverse effects. Here, nanoformulations based on polyethylene glycol modified phospholipid micelles, loaded with both SPIONs and sorafenib, were successfully prepared and thoroughly investigated by complementary techniques. This nanovector system provided effective drug delivery, had an average hydrodynamic diameter of about 125 nm, had good stability in aqueous medium, and allowed controlled drug loading. Magnetic analysis allowed accurate determination of the amount of SPIONs embedded in each micelle. An in vitro system was designed to test whether the SPION micelles can be efficiently held using a magnetic field under typical flow conditions found in the human liver. Human hepatocellular carcinoma （HepG2） cells were selected as an in vitro system to evaluate tumor cell targeting efficacy of the superparamagnetic micelles loaded with sorafenib. These experiments demonstrated that this delivery platform is able to enhance sorafenib＇s antitumor effectiveness by magnetic targeting. The magnetic nanovectors described here represent promising candidates for targeting specific hepatic tumor sites, where selective release of sorafenib can improve its efficacy and safety profile.

关键词： superparamagnetic ironoxide nanoparticles poly(ethylene glycol) (PEG)-modified phospholipidmicelles drug delivery magnetic targeting hepatocellular carcinoma sorafenib

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Contrast-enhanced ultrasound in portal venous system aneurysms: A multi-center study

引用

World Journal of Gastroenterology 2014年第48期20卷 18375-18383页

作者： Claudio Tana Christoph F Dietrich Radu badea Liliana Chiorean Vincenzo Carrieri Cosima Schiavone Unit of Internistic Ultrasound Department of Medicine and Science of Aging "G. d’Annunzio" University 66100 Chieti Italy Internal Medicine Unit Guastalla Hospital 42122 AUSL Reggio Emilia Italy Med Klinik 2 Caritas-Krankenhaus D-97980 Bad Mergentheim Germany Department of Ultrasonography "Octavian Fodor" Institute of Gastroenterology and Hepatology "Iuliu Hatieganu" University of Medicine and Pharmacy 400162 Cluj-Napoca Romania Department of Radiology and Computed Tomography "Octavian Fodor" Institute of Gastroenterology and Hepatology 400162 Cluj-Napoca Romania

AIM: To investigate contrast-enhanced ultrasound (CEUS) findings in portal venous system aneurysms (PVSAs).

关键词： Venous system Portal vein Aneurysm Contrast-enhanced ultrasound Computed tomography Magnetic resonance imaging

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：