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Shear-wave elastography to predict hepatocellular carcinoma after hepatitis C virus eradication:A systematic review and meta-analysis

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World Journal of Gastroenterology 2024年第10期30卷 1450-1460页

作者： Giorgio esposto Paolo Santini Linda Galasso Irene Mignini Maria elena Ainora Antonio Gasbarrini Maria Assunta Zocco CeMAD Digestive Disease Center Fondazione Policlinico Universitario“A.Gemelli”IRCCSCatholic University of RomeRome 00168Italy Fondazione Policlinico Universitario Agostino Gemelli IRCCS Fondazione Policlinico Universitario Agostino Gemelli IRCCS-UniversitàCattolica del Sacro CuoreRome 00168Italy Medicina Interna e Gastroenterologia CEMAD Digestive Disease CenterUniversitàCattolica del Sacro CuoreFondazione Policlinico Universitario A Gemelli IRCCSRome 00168Italy

BACKGROUND Direct-acting antiviral agents(DAAs)are highly effective treatment for chronic hepatitis C(CHC)with a significant rate of sustained virologic response(SVR).The achievement of SVR is crucial to prevent additional liver damage and slow down fibrosis *** assessment of fibrosis degree can be performed with transient elastography,magnetic resonance elastography or shear-wave elastography(SWe).Liver elastography could function as a predictor for hepato-cellular carcinoma(HCC)in CHC patients treated with *** To explore the predictive value of SWe for HCC development after complete clearance of hepatitis C virus(HCV).MeTHODS A comprehensive literature search of clinical studies was performed to identify the ability of SWe to predict HCC occurrence after HCV *** accordance with the study protocol,a qualitative and quantitative analysis of the evidence was *** At baseline and after 12 wk of follow-up,a trend was shown towards greater liver stiffness(LS)in those who go on to develop HCC compared to those who do not[baseline LS standardized mean difference(SMD):1.15,95%confidence interval(95%CI):020-2.50;LS SMD after 12 wk:0.83,95%CI:0.33-1.98].The absence of a statistically significant difference between the mean LS in those who developed HCC or not may be related to the inability to correct for confounding factors and the absence of raw source *** was a statist-ically significant LS SMD at 24 wk of follow-up between patients who developed HCC vs not(0.64;95%CI:0.04-1.24).CONCLUSION SWe could be a promising tool for prediction of HCC occurrence in patients treated with *** studies with larger cohorts and standardized timing of elastographic evaluation are needed to confirm these data.

关键词： Shear-wave elastography Hepatocellular carcinoma Hepatitis C virus Sustained virologic response

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effect of Temper Rolling on Tensile Properties of Low-Si Al-Killed Sheet Steel

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Journal of Iron and Steel Research International 2009年第3期16卷 64-67页

作者： MA Qing-long WANG Dong-cheng LIU Hong-min LU Hai-ming education Ministry engineering Research Center of Rolling equipment and complete Technology State Key Laboratory of Metastable Materials Science and Technology Yanshan University Qinhuangdao 066004 Hebei China ColdStrip Factory of Lingyuan Iron and Steel Group Co Ltd Lingyuan 122500 Liaoning China

The tensile properties of steel after temper rolling are affected by the reduction; low-Si Al-killed sheet steel was taken to study the effect of temper rolling on the tensile properties. The results indicate that the yield strength first decreases with the increase of reduction,and then increases. The relationship between the yield strength and the reduction can be expressed using quadratic function. The tensile strength increases with the increase of the reduction,while the total elongation decreases with the increase of the reduction,and the relationship between them and the reduction can be expressed using power function. Under the same condition,the results also indicate that the yield strength and tensile strength of steels across the rolling direction are all larger than those along the rolling direction; there is no obvious distinction between the total elongation along the rolling direction and that across the rolling direction.

关键词： temper rolling yield strength tensile strength total elongation

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The qqsQ(q=u,d;Q=c,b)tetraquark system in a chiral quark model

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Chinese Physics C 2024年第7期48卷 84-105页

作者：杨刚平加伦 Jorge Segovia Department of Physics Zhejiang Normal UniversityJinhua 321004China Department of Physics and Jiangsu Key Laboratory for Numerical Simulation of Large Scale Complex Systems Nanjing Normal UniversityNanjing 210023China Departamento de Sistemas Físicos Químicos y NaturalesUniversidad Pablo de OlavideE-41013 SevillaSpain

The S-wave qqsQ(q=u,d;Q=c,b)tetraquarks,with spin-paritiesJ^(P)=0^(+),1^(+),and 2^(+),in both isoscalar and isovector sectors,are systematically studied using a chiral quark *** meson-meson,diquark-antidiquark,and K-type arrangements of quarks and all possible color wave functions are comprehensively *** four-body system is solved using the Gaussian expansion method,a highly efficient computational ***,a complex-scaling formulation of the problem is established to disentangle bound,resonance,and scattering *** theoretical framework has already been successfully applied in various tetra-and penta-quark *** the complete coupled channel and within the complex-range formulation,several narrow resonances of qqsC and qqsb systems are obtained,in each allowed I(J^(P))-channel,within the energy regions of 2.4-3.4 GeV and 5.7-6.7GeV,*** predicted exotic states,which indicate a richer color structure when going towards multiquark systems beyond mesons and baryons,are expected to be confirmed in future high-energy particle and nuclear experiments.

关键词： quantum chromodynamics quark models

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Using the *** website to obtain robust phylogenies for avian comparative studies： A primer

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Current Zoology 2015年第6期61卷 959-965页

作者： Diego RUBOLINI Andras LIKeR Laszlo Z. GARAMSZeGI Anders P. MOLLeIR Nicola SAINO Dipartimento di Bioscienze Universita degli Studi di Milano via Celoria 26 1-20133 Milano Italy Department of Limnology University of Pannonia Pf. 158 H-8201 Veszpr6m Hungary Department of evolutionary ecology Estaci6n Biol6gica de Dofiana-CSIC c/Americo Vespucio s/n E-41092 Seville Spain Laboratoire ecologie Systematique et Evolution UMR 8079 CNRS Universit6 Paris-Sud XI-AgroParisTech Batiment 362 Universit6 Paris-Sud XI F-91405 Orsay Cedex France

Comparative studies of trait evolution require accounting for the shared evolutionary history. This is done by includ- ing phylogenetic hypotheses into statistical analyses of species＇ traits, for which birds often serve as excellent models. The online publication of the most complete molecular phylogeny of extant bird species （***, BirdTree hereafter） now allows evolutionary biologists to rapidly obtain sets of equally plausible phylogenetic trees for any set of species to be incorporated as a phylogenetic hypothesis in comparative analyses. We discuss methods to use BirdTree tree sets for comparative studies, either by building a consensus tree that can be incorporated into standard comparative analyses, or by using tree sets to account for the ef- fect of phylogenetie uncertainty. Methods accounting for phylogenetic uncertainty should be preferred whenever possible because they should provide more reliable parameter estimates and realistic confidence intervals around them. Based on a real compara- tive dataset, we ran simulations to investigate the effect of variation in the size of the random tree sets downloaded from BirdTree on the variability of parameter estimates from a bivariate relationship between mass-specific productivity and body mass. Irre- spective of the method of analysis, using at least 1,000 trees allows obtaining parameter estimates with very small （〈 0.15%） co- efficients of variation. We argue that BirdTree, due to the ease of use and the major advantages over previous ＇traditional＇ meth- ods to obtain phylogenetic hypotheses of bird species （e.g. supertrees or manual coding of published phylogenies）, will become the standard reference in avian comparative studies for years to come.

关键词： Birds BirdTree Comparative method PGLM PGLS Phylogenetic uncertainty

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Standard-Cell Placement from Functional Descriptions

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Journal of Computer Science & Technology 1991年第1期6卷 37-46页

作者： Klaus Buchenrieder Waldparkstraβe

This paper presents a functional language for the unambiguous description of digital circuits,a me- thod and algorithms to obtain a standard-cell layout,and a comparative evaluation of the developed func- tional standard-cell placement *** presented placement scheme is different from traditional methods because the complete layout geometry is specified and constructed automatically from a function- al *** construction relies on a translation that combines the simplicity of standard-cells with the elegance of functional *** evaluation of the method introduced shows that the quality of the resulting placement is close to the results achieved with simulated annealing while the computation time is significantly ***,the evaluation suggests to employ the functional placement me- thod in conjunction with low-temperature simulated annealing for running-time reduction and improved- results.

关键词： Standard-Cell Placement from Functional Descriptions

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Flatness and Profile Integration Control Model for Tandem Cold Mills

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Journal of Iron and Steel Research International 2012年第3期19卷 31-37页

作者： SHAN Xiu-ying1,2,3, LIU Hong-min1,2, JIA Chun-yu1,2, SUN Jian-liang1,2 (1. engineering Research Center of Rolling equipment and complete Technology of Ministry of education, Yanshan University, Qinhuangdao 066004, Hebei, China 2. State Key Laboratory of Metastable Materials Science and Technology, Yanshan University, Qinhuangdao 066004, Hebei, China 3. Hot Tandem Rolling Factory, Jinan Iron and Steel Co Ltd, Jinan 250101, Shandong, China) engineering Research Center of Rolling equipment and complete Technology of Ministry of education Yanshan University Qinhuangdao Hebei China State Key Laboratory of Metastable Materials Science and Technology Yanshan University Qinhuangdao Hebei China Hot Tandem Rolling Factory Jinan Iron and Steel Co Ltd Jinan Shandong China

Using the effective matrix methods of flatness and profile control synthetically, the flatness and profile in- tegration control scheme for tandem cold mills is built in order to increase flatness and profile control precision of tan- dem cold mills. Corresponding control strategies are adopted for various control objectives of different stands and the coordination control strategies of various stands are given, which makes the on-line flatness control cooperate with on-line profile control and implements the parallel control of different stands. According to the measured flatness and profile data of some 1550 mm tandem cold mills, the control scheme is verified and the result indicates that the scheme has high flatness and profile control precision with steady and reliable control process. A new way and method is supplied for researching shade control of tandem cold mills.

关键词： flatness profile shape effective matrix tandem cold mill

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基于主从力反馈的同构主手设计与研究

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机械设计与研究 2024年第1期40卷 63-68页

作者：陈铮王晨麟夏华磊刘振武张伟军上海交通大学机械与动力工程学院上海200240E-mail:zhangweijun@*** 国网徐州供电公司江苏徐州221000

在变电站场景中,巡检机器人已经逐步取代人工巡检作业。但现有机器人存在遥操作效率低、无法很好地实现拟人化操作等问题,难以完成变电站巡检作业中急停、拉闸等接触性操作任务,亟需研发对变电站巡检具有高适应性的协同作业机器人。针... 详细信息

在变电站场景中,巡检机器人已经逐步取代人工巡检作业。但现有机器人存在遥操作效率低、无法很好地实现拟人化操作等问题,难以完成变电站巡检作业中急停、拉闸等接触性操作任务,亟需研发对变电站巡检具有高适应性的协同作业机器人。针对变电站巡检处置应用需求,开展了基于主从力反馈的巡检机器人遥操作技术研究,设计了一款串联型同构主手,结构上主从映射关系直接,控制上力反馈双向控制完整,实现了六自由度机械臂主从力反馈,便于进行精细化操作。开展主从力反馈技术研究,通过构建和简化动力学模型实现负载、摩擦力补偿,采用力直接反馈型双向控制策略。完成样机研制并进行了功能验证和精度测试实验,结果表明主手能够较好地完成巡检操作基本任务,力反馈误差小于7%,机械臂末端跟踪精度优于2 mm,验证了机械结构及控制系统的有效性。

关键词：巡检机器人同构主手主从控制力反馈

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CCD/eMCCD光电参数测试系统的设计与应用

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中国光学（中英文） 2024年第3期17卷 693-703页

作者：沈吉 VIACHeSLAV V.Zabudsky 常维静那启跃简云飞 OLeG V.Rikhalsky OLeKSANDR G.Golenkov VOLODYMYR P.Reva 华东光电集成器件研究所江苏苏州215263 乌克兰科学院V.e.Lashkaryov半导体物理研究所乌克兰基辅01001 乌克兰科学院Bogomoletz生理学研究所乌克兰基辅01001

本文开发了一种用于测量CCD和eMCCD(电子倍增CCD)芯片光电参数的测试系统。该测试系统通过自动模式或手动模式间的切换,测量器件的暗电流、读出放大器的响应度、电荷转移效率、电荷容量和其他参数。该测试系统可以针对不同规格和结构的C... 详细信息

本文开发了一种用于测量CCD和eMCCD(电子倍增CCD)芯片光电参数的测试系统。该测试系统通过自动模式或手动模式间的切换,测量器件的暗电流、读出放大器的响应度、电荷转移效率、电荷容量和其他参数。该测试系统可以针对不同规格和结构的CCD/eMCCD器件,实现CCD晶圆或封装好的成品的参数测试,实现576×288、640×512、768×576、1024×1024、1280×1024 CCD/eMCCD的测试和筛选。

关键词： CCD eMCCD 测试系统光电参数

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Flatness Control Based on Dynamic effective Matrix for Cold Strip Mills

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Chinese Journal of Mechanical engineering 2009年第2期22卷 287-296页

作者： LIU Hongmin He Haitao SHAN Xiuying JIANG Guangbiao engineering Research Center of Rolling equipment and complete Technology of Ministry of education Yanshan University Qinhuangdao 066004 China State Key Laboratory of Metastable Materials Science ＆ Technology Yanshan University Qinhuangdao 066004 China College of Information Science and engineering Yanshan University Qinhuangdao 066004 China Baogang Branch Baoshan Iron and Steel Co. Ltd. Shanghai 200941 China

Steel strips are the main of steel products and flatness is an important quality indicator of steel strips. Flatness control is the key and highly difficult technique of strip mills. The bottle-neck restricting the improvement of flatness control techniques is that the research on flatness theories and control mathematic models is not in accordance with the requirement of technique developments. To build a simple, rapid and accurate explicit formulation control model has become an urgent need for the development of flatness control technique. This paper puts forward the conception of dynamic effective matrix based on the effective matrix method for flatness control proposed by the authors under the consideration of the influence of the change of parameters in roiling processes on the effective matrix, and the concept is validated by industrial productions. Three methods of the effective matrix generation are induced： the calculation method based on the flatness prediction model; the calculation method based on the data excavation in rolling processes and the direct calculation method based on the network model. A fuzzy neural network effective matrix model is built based on the clusters, and then the network structure is optimized and the high-speed-calculation problem of the dynamic effective matrix is solved. The flatness control scheme for cold strip mills is proposed based on the dynamic effective matrix. On stand 5 of the 1 220 mm five-stand 4-high cold strip tandem mill, the industrial experiment with the control methods of tilting roll and bending roll is done by the control scheme of the static effective matrix and the dynamic effective matrix, respectively. The experiment result proves that the control effect of the dynamic effective matrix is much better than that of the static effective matrix. This paper proposes a new idea and method for the dynamic flatness control in the rolling processes of cold strip mills and develops the theory and model of the fl

关键词： cold strip mill flatness control dynamic effective matrix cluster fuzzy neural network

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Neural network learns physical rules for copolymer translocation through amphiphilic barriers

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npj Computational Materials 2020年第1期6卷 1039-1046页

作者： Marco Werner Yachong Guo Vladimir A.Baulin Institute Theory of Polymers Leibniz-Institut für Polymerforschung Dresden e.V.Hohe Straße 601069 DresdenGermany Departament d’enginyeria Química Universitat Rovira i Virgili26 Av.dels Paisos Catalans43007 TarragonaSpain Kuang Yaming Honors School Nanjing University22 Hankou Road210093 NanjingChina

Recent developments in computer processing power lead to new paradigms of how problems in many-body physics and especially polymer physics can be *** processors can be exploited to generate millions of molecular configurations in complex environments at a second,and concomitant free-energy landscapes can be *** that are complete in terms of polymer sequences and architecture form a powerful training basis for cross-checking and verifying machine learning-based *** employ an exhaustive enumeration of polymer sequence space to benchmark the prediction made by a neural *** our example,we consider the translocation time of a copolymer through a lipid membrane as a function of its sequence of hydrophilic and hydrophobic ***,we demonstrate that massively parallel Rosenbluth sampling for all possible sequences of a polymer allows for meaningful dynamic interpretation in terms of the mean first escape times through the ***,we train a multi-layer neural network on logarithmic translocation times and show by the reduction of the training set to a narrow window of translocation times that the neural network develops an internal representation of the physical rules for sequencecontrolled diffusion *** on the narrow training set,the network result approximates the order of magnitude of translocation times in a window that is several orders of magnitude wider than the training *** investigate how prediction accuracy depends on the distance of unexplored sequences from the training window.

关键词： neural network narrow

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