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High order aberration and straylight evaluation after cataract surgery with implantation of an aspheric,aberration correcting monofocal intraocular lens

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International Journal of Ophthalmology(English edition) 2015年第4期8卷 736-741页

作者： Florian T A Kretz Tamer Tandogan Ramin Khoramnia Gerd U Auffarth International Vision Correction Research Centre & David J Apple International Laboratory for Ocular Pathology of the Department of Ophthalmology University Hospital Heidelberg International Vision Correction Research Network (***) augenklinik Ahaus-Raesfeld-Rheine Gerl Group

·AIM: To evaluate the quality of vision in respect to high order aberrations and straylight perception after implantation of an aspheric, aberration correcting,monofocal intraocular lens(IOL).·METHODS: Twenty-one patients(34 eyes) aged 50 to83 y underwent cataract surgery with implantation of an aspheric, aberration correcting IOL(Tecnis ZCB00,Abbott Medical Optics). Three months after surgery they were examined for uncorrected(UDVA) and corrected distance visual acuity(CDVA), contrast sensitivity(CS)under photopic and mesopic conditions with and without glare source, ocular high order aberrations(HOA, Zywave II) and retinal straylight(C-Quant).· RESULTS: Postoperatively, patients achieved a postoperative CDVA of 0.0 log MAR or better in 97.1% of eyes. Mean values of high order abberations were +0.02±0.27(primary coma components) and-0.04 ±0.16(spherical aberration term). Straylight values of the C-Quant were 1.35±0.44 log which is within normal range of age matched phakic patients. The CS measurements under mesopic and photopic conditions in combination with and without glare did not show any statistical significance in the patient group observed(P ≥0.28).· CONCLUSION: The implantation of an aspherical aberration correcting monofocal IOL after cataractsurgery resulted in very low residual higher order aberration(HOA) and normal straylight.

关键词： cataract aberrations intraocular lens

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钌106板近距离放射治疗有临床表现的血管增生性视网膜肿瘤

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世界核心医学期刊文摘（眼科学分册） 2006年第9期2卷 33-34页

作者： Anastassiou G. Bornfeld N. Schueler A. O. 刘瑛(译) augenklinik Universitaetsklinikum Essen 45122 Essen Germany 不详

Aim:To investigate the safety and efficacy of β ray brachytherapy in treatment of vasoproliferative tumours of the retina(VTR).Methods:35 consecutive patients with symptomatic VTR were treated with a ruthenium-106(106Ru)*** tumours had been treated previously(two with cryotherapy;one with transpupillary thermotherapy).32 VTR(91.4%)were located in the lower half of the retina and all of them were found between the mid-periphery and the ora *** mean tumour thickness was 2.8 *** exudative retinal detachment was present in 25 eyes(71.4%)and in 15 cases(42.9%)hard exudates were found in the *** major symptom was loss of vision(77.1%).Results:Brachytherapy was well tolerated by every *** mean applied dose was 416 Gy at the sclera and 108 Gy at the tumour *** all but four eyes(88.6%),it was possible to control the VTR *** median follow up time was 24 *** of the above mentioned four eyes with treatment failure had had secondary glaucoma before *** was no case of radiation induced neuropathy or *** surgery was necessary for five *** development of epiretinal gliosis was the most common event during follow up(n=10,28.6%).The mean visual acuity decreased slightly(0.33 before and 0.29 after brachytherapy).Multivariate analysis showed that the presence of macular pathology before treatment was associated with a 6.1-fold risk of vision of 0.25 or better(p= 0.03).Conclusions:β ray brachytherapy with 1106Ru plaques was able to control the activity of VTR and retain *** with secondary glaucoma before treatment had a very poor prognosis.

关键词：近距离放射治疗视网膜肿瘤增生性临床表现血管渗出性视网膜脱离继发性青光眼钌

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通过H.-***测量和校正方法的棱柱性校正小度数内斜视的可行性

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世界核心医学期刊文摘（眼科学分册） 2006年第6期2卷 28-29页

作者： Kromeier M. Kommerell G. 王永强(译) 不详 Universitaets- augenklinik Freiburg Killianstralβe 5 79106 Freiburg Germany

Background: The “ Measuring and Correcting Methodology after H.-J. Haase” is based on the assumption that a minute deviation from the orthovergence position (fixation disparity)-indicates a difficulty to overcome a larger “ vergence angle of rest” . Objective recordings have,however,revealed that the subjective tests applied in the “ Measuring and Correcting Methodology after H.-J. Haase” can mislead to the assumption of a fixation disparity,although both eyes are aligned exactly to the fixation point. Question: How do patients with an inconspicuosly small,yet objectively verified strabismus react to the “ Measuring and Correcting Methodology by H.-J. Haase” ? Methods: Eight patients with amicroesotropia between 0.5 and 3° were subjected to the “ Measuring and Correcting Methodology after H.-J. Haase” . Results: In all 8 patients,the prisms determined with the Cross-,Pointer-and Rectangle Tests increased the angle of squint,without reaching a full correction: the original angle prevailed. In the Stereobalance Test,prisms did not reduce the 100% preponderance of the non-squinting eye. The stereoscopic threshold was between 36 and 1170 arcsec in 7 out of the 8 subjects,and above 4000 arcsec in 1 subject. Conclusions: (1) In all 8 patients,prisms determined with the “ Measuring and Correcting Methodology by H.-J. Haase” increased the angle of strabismus,without reaching bifoveal vision. This uniform result suggests that primary microesotropia cannot be corrected with the “ Measuring and Correcting Methodology after H.-J. Haase” (2) A lacking contribution of the strabismic eye to the recognition of a lateral off-set between stereo objects,as determined with the Stereobalance Test,does not imply a lack of binocular stereopsis.

关键词： Haase 校正方法斜视度数内斜视测量平衡试验患者斜视角法理视差

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玻璃体腔内注射曲安奈德治疗视网膜分支静脉阻塞

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世界核心医学期刊文摘（眼科学分册） 2005年第6期1卷 37-38页

作者： Jonas J.B. Akkoyun I. Kamppeter B. 宋虎平 Universit¨ats-augenklinik Theodor-Kutzer-Ufer 1- 3 Mannheim 68167 Germany

Purpose. To evaluate the effect of intravitreal triamcinolone acetonide on visual acuity in branch retinal vein occlusion. Methods. The prospective comparative nonrandomized clinical interventional study included 28 patients (28 eyes) with branch retinal vein occlusion. The study group consisting of 10 consecutive patients received an intravitreal injection of 20- 25mg of triamcinolone acetonide. The control group including 18 patients did not receive an intravitreal injection. The mean follow-up was 8.7± 4.4 months. Results. In the study group, mean visual acuity increased significantly (P=0.02) from 0.27± 0.11 preoperatively to a best postoperative visual acuity of 0.45± 0.27. Visual acuity measurements determined 1 month after the injection were significantly (P=0.027) higher than baseline values. Nine (90% ) eyes gained in visual acuity, with six (60% ) eyes showing an increase in visual acuity of at least two Snellen lines. In the ischaemic subgroup, visual acuity did not change significantly (0.18± 0.18 to 0.13± 0.04; P=0.66), while, in the nonischaemic subgroup, visual acuity increased significantly (P=0.012) from the baseline value to the best postoperative measurement (0.29± 0.09 to 0.53± 0.24). In the control group, baseline visual acuity and best visual acuity during the follow-up did not vary significantly (P=0.27). Comparing the study and control groups with each other, the gain in visual acuity was significantly higher in the study group at 1 month (P=0.016) and 2 months (P=0.012) after baseline. Conclusions. Intravitreal injection of triamcinolone acetonide can increase visual acuity in patients with branch retinal vein occlusion.

关键词：腔内注射分支静脉阻塞平均视力最佳视力缺血型基线值临床干预亚组对照性

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离焦对多焦视觉诱发电位的影响

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世界核心医学期刊文摘（眼科学分册） 2005年第6期1卷 44-45页

作者： Pieh C. Hoffmann M.B. Bach M. 张磊 Sektion Funktionelle Sehforschung Universit ts-Augenklinik Killianstrafle 5 79106 Freiburg Germany

Background: In order to assess the influence of optical factors on the multifocal visual evoked potential (mfVEP), we obtained mfVEPs with optimal refraction and compared them to recordings with various degrees of dioptrical defocus. Methods: Monocular mfVEPs were recorded from the right eye in eight normal subjects. Dartboard stimuli with 60 sectors arranged in six concentric annuli spanning 60° were generated with a VERIS system and presented on a computer monitor. Two pairs of electrodes were placed 3 cm above and below and 3 cm to the right and left of the inion. Two sets of mfVEP records per subject were obtained, one with best-corrected visual acuity and another when the stimulus was defocused by+ 1.0,+ 2.0 or + 3.0 D. A signal-to-noise ratio (SNR) measure was calculated for every response from the two channels. Results: The effect of defocus depended on eccentricity: When defocus was at + 2.0 D and higher, reducing visual acuity to 7° . Conclusions: The results suggest that, in contrast to the mfERG, the mfVEP requires optimal refraction to correctly assess the cortical responses.

关键词：离焦屈光状态计算机屏幕焦值枕骨隆突视力矫正矫正视力皮质反应视标测量电极

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丝裂霉素C在准分子激光屈光性角膜手术中的应用:初步经验及文献回顾

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世界核心医学期刊文摘（眼科学分册） 2005年第11期1卷 60-61页

作者： Kottler U.B. Dick H.B. 陈立军 Universitts-augenklinik Langenbec kstrae 1 55131 Mainz GermanyProf.

Haze formation with loss of corneal transparency and surface irregularities an d myopic regression are the major complications after corneal refractive surface surgery. The use of mitomycin C (MMC) with its antibiotic and antineoplastic pr operties is intended to inhibit wound healing mechanisms leading to subepithelia l fibrosis. We report the use of MMC to achieve visual rehabilitation in the re -treatment of 3 eyes of 2 patients following refractive corneal surgery. According to the literatur e, the local use of MMC 0.02%for 2 minutes is safe and enables one to treat and prevent stromal haze and myopic regression and allows a reduction of the postop erative topical pharmacotherapy. Results are still limited due to small case num bers and short follow-up periods.

关键词：屈光性角膜准分子激光文献回顾初步经验近视回退修复反应用药量局部应用样本量

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人工角膜支持部为生物相容性或生物性材料的中期结果

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世界核心医学期刊文摘(眼科学分册) 2006年第11期 23-24页

作者： Hille K. Hille A. Ruprecht K.W. 宋虎平 Universitts-augenklinik Kirrberger Str 166421 Homburg/SaarGermany

Purpose:Corneal grafts or limbal stem cell transplantation are often unsuccessful in patients with severe ocular surface disorders such as severe dry eye syndrome,symblepharon or diffuse *** those patients,a keratoprosthesis(KPro) may be an alternative for the recovery of *** KPro differ from each other in the material of the haptic that supports the optic *** haptic may be made of biocompatible or biological material such as tibia bone(TKPro) or dentine and alveolar bone(osteo-odonto-keratoprosthesis,OOKP) .On the basis of our experience,we wanted to comment on the value of different ***:Over the last 10 years we have implanted a total of 35 K Pro,29 with biological haptic(25 OOKP and four TKPro) ,and six KPro with biocompatible haptic(one Legais KPro,five Pintucci KPro) .A follow up examination was carried out approximately every 6 ***:The patients gained a visual acuity of ≥ 0.9 in 20.6%,of ≥ 0.5 in 52.9%,of ≥ 0.2 in 61.8% and a significant improvement in visual acuity in 76.5%,*** was no significant difference between the various types of KPro concerning the best postoperative visual *** patients showing poor improvement had a pre-existing end stage secondary glaucoma or other retinal *** median follow-up was 2.9 years(maximum 8) for OOKP,1 year for TKPro,1 year(maximum 2) for Pintucci Kpro and 6 month for Legeais *** this period,only one of the KPro with biological haptic was lost(one TKPro after 1 year) ,compared with four out of six of the KPro with biocompatible haptic(P< 0.000 1) .Conclusions:Fixation of the KPro by a root of the patient;s own tooth(OOKP) leads to the best results in the long-term follow up,as our results as well as the literature *** long as a KPro is in place,the visual acuity is as good as the retinal *** the ranking of different types of KPro,the percentage and the duration of the anatomic success are most *** compar

关键词：生物相容性人工角膜人工器官

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两种超声生物检测方法与Zeiss IOL-Master计算后房型人工晶体的比较研究

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世界核心医学期刊文摘（眼科学分册） 2005年第4期1卷 49-50页

作者： Remsch H. Kampmeier J. Muche R. 杨建刚 Universittsklinikum Ulm Augenklinik Prittwitzstr. 43 89075 Ulm Germany Dr

Background: The aim of this work was to investigate the accuracy of prediction of three different biometric methods for the calculation of posterior chamber intraocular lenses. Methods: In 59 consecutive patients who underwent extracapsular cataract- extraction with posterior chamber intraocular lens implantation, we compared the refractive results at the first day (D1) and 6 weeks (W6) after surgery with the calculated refraction of three biometric methods: the Carl Zeiss “ IOL- Master 99” (IOLM), the Biovision “ Echograph Class 1- Type B” (BIOV) and the Allergan Humphrey “ Ultrasonic Biometer Mod. 820” (AHUB). For statistical calculation box- plots, the Wilcoxon signed- rank test and linear regression analysis were used. Results: In all patients the mean of the postoperative refraction was - 0.07 D (SD: 1.41) at day 1 and 0.12 D (SD: 1.18) at week 6. Compared to the postoperative refraction at week 6, the calculated refractive values were higher in all three measuring devices: IOLM: + 0.28 D (SD: 0.67), BIOV: + 0.60 D (SD: 0.88), AHUB:+ 0.26 D (SD: 0.92). There were no statistically significant differences between IOLM and BIOV, or respectively, AHUB and BIOV (P < 0.000 1), but a significant difference was found between IOLM and AHUB, (P=0.906). To adjust for systematic differences of the agreement, one can calculate the postoperative refraction at week 6 (REF6) from IOLM by using the linear regression formula: REF6=1.1 × .IOLM+ 0.3. Conclusion: A comparison between the three biometric methods and the refractive results at day 1 and week 6 after cataract surgery with implantation of a posterior chamber intraocular lens showed that the calculated mean values obtained from the three biometric methods are higher than the real postoperative refraction. Calculations using the Zeiss IOL- Master and the Allergan Humphrey Ultrasonic Biometer are closer to the patient’ s postoperative refraction than calculations using the Biovision Echograph.

关键词：后房型人工晶体 Zeiss 生物检测方法白内障囊外摘除预测准确性计算术符号秩检验蔡斯 aster 线性回归

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Microstructural morphology and visual acuity outcome in eyes with epiretinal membrane before,during,and after membrane peeling in intraoperative optical coherence tomography assisted macular surgery

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International Journal of Ophthalmology(English edition) 2023年第5期16卷 748-754页

作者： Melanie Weschta Moritz Pettenkofer Julian EKlaas Nikolaus Feucht Chris PLohmann Mathias Maier Department of Ophthalmology Klinikum rechts der IsarTechnische Universität MünchenIsmaninger Str.22Munich 81675Germany Jules Stein Eye Institute University of California Los Angeles100 Stein Plaza DrivewayLos AngelesCalifornia 90095USA Department of Ophthalmology Ludwig-Maximilians-Universität MünchenMathildenstr.8Munich 80336Germany Smile Eyes augenklinik Munich Airport Terminalstraße Mitte 18Munich 85356Germany

AIM:To measure the difference of intraoperative central macular thickness(CMT)before,during,and after membrane peeling and investigate the influence of intraoperative macular stretching on postoperative best corrected visual acuity(BCVA)outcome and postoperative CMT ***:A total of 59 eyes of 59 patients who underwent vitreoretinal surgery for epiretinal membrane was *** with intraoperative optical coherence tomography(OCT)were *** of intraoperative CMT before,during,and after peeling was ***-and postoperatively obtained BCVA and spectral-domain OCT images were ***:Mean age of the patients was 70±8.13y(range 46-86y).Mean baseline BCVA was 0.49±0.27 log MAR(range 0.1-1.3).Three and six months postoperatively the mean BCVA was 0.36±0.25(P=0.01 vs baseline)and 0.38±0.35(P=0.08 vs baseline)log MAR *** stretch of the macula during surgery was 29%from baseline(range 2%-159%).Intraoperative findings of macular stretching did not correlate with visual acuity outcome within 6mo after surgery(r=-0.06,P=0.72).However,extent of macular stretching during surgery significantly correlated with less reduction of CMT at the fovea centralis(r=-0.43,P<0.01)and 1 mm nasal and temporal from the fovea(r=-0.37,P=0.02 and r=-0.50,P<0.01 respectively)3mo ***:The extent of retinal stretching during membrane peeling may predict the development of postoperative central retinal thickness,though there is no correlation with visual acuity development within the first 6mo postoperatively.

关键词： retinal imaging treatment surgery intraoperative optical coherence tomography epiretinal membrane

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视盘大小与屈光不正相关

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世界核心医学期刊文摘（眼科学分册） 2005年第7期1卷 14-15页

作者： Jonas J.B. 司冰心 Universitts- augenklinik Theodor- Kutzer- Ufer 1- 3 68167 Mannheim Germany

Purpose: To evaluate for which range of refracAbstract:tive error the optic disk size depends on,or is independent of, the refractive error. Design: Clinical observational study. Methods: The study included 1999 eyes of 1011 subjectswith a mean refractive error of- 0.97± 2.72 diopters (range,- 24.25 to + 9.4 diopters). Optic disk photographs were morphometrically evaluated. Results: The relation between optic disk area and refractive error showed a curvilinear shape, with a steep increase toward high myopia starting at- 8 diopters, and a decrease toward high hyperopia starting at + 4 diopters. Conclusion: The optic disk size depends on the refractive error with an increase in highly myopic eyes beyond- 8 diopters and a decrease in highly hyperopic eyes beyond + 4 diopters. Confirming histomorphometric studies, the limits of- 8 diopters and + 4 diopters may be discussed to refine the definitions of high hyperopia and high myopia.

关键词：屈光不正高度近视高度远视临床观察形态学研究

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