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Gingival Metastasis Revealing Lung Adenocarcinoma

Advances in Lung Cancer 2014年第2期3卷 35-37页

作者： Lamyae Amro Leila Maliki Badia Belabidia Abdelhaq Alaoui Yazidi anatomopathology departement Ibn Tofail Hospital CHU Mohammed VI FMPM Cadi Ayyad University Marrakech Morocco Pulmonary departement Ibn Nafis Hospital CHU Mohammed VI Laboratory PCIM FMPM Cadi Ayyad University Marrakech Morocco

Introduction:?The lung adenocarcinoma is an invasive malignant tumor. Its visceral metastases are multiple. The gingival location is uncommon if not exceptional. Observation: We report the case of 66-year-old patient with a right cervical radiculopathology. Clinical examination objectified a superior vena cava syndrome with gingival tumor budding whose excisional biopsy found a location of a poorly differentiated and infiltrating carcinoma. The bronchoscopy revealed a tumor nodule obstructing the right mainstem bronchus with the histological study concluded as a moderately differentiated adenocarcinoma infiltrating. Conclusion: Gingival metastasis revealing lung adenocarcinoma is uncommon even exceptional. It may delay the diagnosis and management of already poor prognosis.

关键词： Gingival Metastasis Lung Cancer Adenocarcinoma

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Lupus Nephritis Class II: A Challenging Entity

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Open Journal of Nephrology 2022年第2期12卷 203-213页

作者： Basmat Amal Chouhani Ghita Elbardai Laila Tahiri Elousrouti Nadia Kabbali Hind Elfatemi Tarik Sqalli Houssaini Nephrology Dialysis and Transplantation Departement Hassan II University Hospital Fez Morocco Laboratory of Epidemiology and Health Science Research (ERESS) Faculty of Medicine-Fez Sidi Mohammed Ben Abdelalh University Fez Morocco anatomopathology Department Hassan II University Hospital Fez Morocco Laboratory of Translational and Biomedical Research (RBT) Faculty of Medicine-Fez Sidi Mohammed Ben Abdellah University Fez Morocco

Most of the literature focused on the proliferative forms of the lupic Glomerulonephritis. Clinicians are increasingly confronted with cases of lupic nephropathy purely mesangial (class II). The aim of our study is to describe the mode of presentation of the class II Lupus nephropathy, evaluate its evolutionary profile, and investigate possible risk factors for therapeutic misresponse, relapse or histological transformation. This is a retrospective descriptive and analytical study conducted in nephrology depratement at the Hassan II university hospital Fez from January 2009 until September 2018. We included 20 patients. The average age was 33.8 ± 7.25 years [22 - 50 years]. Nephropathy was inaugurated in half of the cases. The mean time of onset of nephropathy in relation to the lupic disease was 36.7 ± 45.4 months [1 - 144 months]. The main reason for consultation was non-nephrotic proteinuria (65%). Renal failure revealed diagnosis in three patients. All patients had a positive immunologic assessment. 90% of our patients received oral corticosteroid therapy with immunosuppressive therapy in 3 cases. Remission has been noted in all of our patients. After an average follow-up period of 39 ± 23 months [6 - 92 months], 45% relapsed. A second biopsy was performed in 80% of patients showing histologic transformation in four patients, requiring immunosuppressive therapy. The analytical study showed that the occurrence of relapse was significantly related to the presence of a known Lupus and its seniority. Proteinuria at 12 months was also significantly higher in the relapsed group. One patient died as a result of neurological complications. Another has Evolved into chronic end stage renal failure and has been put on hemodialysis.

关键词： Lupus Nephritis Mesangial Nephropathy Relapse

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