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First report on molecular characterization of Leishmania species from cutaneous leishmaniasis patients in southern Khyber Pakhtunkhwa province of Pakistan

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Asian Pacific Journal of Tropical Medicine 2017年第7期10卷 785-788页

作者： Mubbashir Hussain Shahzad Munir Sultan Ayaz Bahar Ullah Khattak Taj Ali Khan Niaz Muhammad Muhammad Anees Hazir Rahman Muhammad Qasim Muhammad ameen Jamal Irfan Ahmed Kashif Rahim Humaira Mazhar Noha Watanay Mohamed Kasbari Vector Borne Diseases Laboratory Department of MicrobiologyKohat University of Science and Technology Kohat Department of Plant Pathology Faculty of Plant ProtectionYunnan Agricultural University College of Animal Husbandry and Veterinary Sciences Abdul Wali Khan University Mardan College of Animal Science and Technology Yunnan Agricultural University Yunnan Provincial Key Laboratory of Animal Nutrition and Feed Yunnan Agricultural University Beijing Key Laboratory of Genetic Engineering Drug and Biotechnology Institute of Biochemistry and BiotechnologyCollege of Life SciencesBeijing Normal University US Naval Medical Research Unit-3 (NAMRU 3) ANSES Animal Health Laboratory

Objective: To report presence of Leishmania major in Khyber Pakhtunkhwa of Pakistan, where cutaneous leishmaniasis(CL) is endemic and was thought to be caused by Leishmania tropica only. Methods: Biopsy samples from 432 CL suspected patients were collected from 3 southern districts of Khyber Pakhtunkhwa during years 2011–2016. Microscopy on Giemsa stained slides were done followed by amplification of the ribosomal internal transcribed spacer 1 gene. Results: Leishmania amastigotes were detected by microscopy in 308 of 432 samples(71.3%) while 374 out of 432 samples(86.6%) were positive by ribosomal internal transcribed spacer 1 PCR. Subsequent restriction fragment length polymorphism confirmed Leishmania tropica in 351 and Leishmania major in 6 biopsy samples. Conclusions: This study is the first molecular characterization of Leishmania species in southern Khyber Pakhtunkhwa. It confirmed the previous assumptions that anthroponotic CL is the major CL form present in Khyber Pakhtunkhwa province. Furthermore, this is the first report of Leishmania major from a classical anthroponotic CL endemic focus identified in rural areas of Kohat district in southern Khyber Pakhtunkhwa.

关键词： Cutaneous leishmaniasis ITS-PCR RFLP Leishmania tropica Khyber Pakhtunkhwa

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A Blockchain-Based Architecture for Securing Industrial IoTs Data in Electric Smart Grid

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Computers, Materials & Continua 2023年第3期74卷 5389-5416页

作者： Samir M.Umran Songfeng Lu Zaid ameen Abduljabbar Xueming Tang School of Cyber Science and Engineering Huazhong University of Science and TechnologyWuhan430074China Iraqi Ministry of Industrial and Minerals Iraqi Cement State CompanyBaghdad10011Iraq Shenzhen Huazhong university of Science and Technology Research Institute Shenzhen 518057China Department of Computer Science College of Education for Pure SciencesUniversity of BasrahBasrah61004Iraq

There are numerous internet-connected devices attached to the industrial process through recent communication technologies,which enable machine-to-machine communication and the sharing of sensitive data through a new technology called the industrial internet of things(IIoTs).Most of the suggested security mechanisms are vulnerable to several cybersecurity threats due to their reliance on cloud-based services,external trusted authorities,and centralized architectures;they have high computation and communication costs,low performance,and are exposed to a single authority of failure and *** technology(BC)is widely adopted in the industrial sector for its valuable features in terms of decentralization,security,and *** our work,we propose a decentralized,scalable,lightweight,trusted and secure private network based on blockchain technology/smart contracts for the overhead circuit breaker of the electrical power grid of the Al-Kufa/Iraq power plant as an industrial *** proposed scheme offers a double layer of data encryption,device authentication,scalability,high performance,low power consumption,and improves the industry’s operations;provides efficient access control to the sensitive data generated by circuit breaker sensors and helps reduce power *** also address data aggregation operations,which are considered challenging in electric power smart *** utilize a multi-chain proof of rapid authentication(McPoRA)as a consensus mechanism,which helps to enhance the computational performance and effectively improve the *** advanced reduced instruction set computer(RISC)machinesARMCortex-M33 microcontroller adopted in our work,is characterized by ultra-low power consumption and high performance,as well as efficiency in terms of real-time cryptographic algorithms such as the elliptic curve digital signature algorithm(ECDSA).This improves the computational execution,increases the implementation speed of the asymmetric c

关键词： Smart grids industrial IoTs electric power system blockchain technology IoT applications industry 4.0 decentralization applications

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On the rate of convergence of the Legendre spectral collocation method for multidimensional nonlinear Volterra-Fredholm integral equations

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Communications in Theoretical Physics 2021年第2期73卷 11-22页

作者： Nermeen A Elkot Mahmoud A Zaky Eid H Doha Ibrahem G ameen Department of Mathematics Faculty of ScienceCairo UniversityGiza 12613Egypt Department of Applied Mathematics National Research CentreDokkiCairo 12622Egypt Department of Mathematics Faculty of ScienceAl-Azhar UniversityCairoEgypt

While the approximate solutions of one-dimensional nonlinear Volterra-Fredholm integral equations with smooth kermels are now well understood,no systematic studies of the numerical solutions of their multi-dimensional counterparts *** this paper,we provide an efficient numerical approach for the multi-dimensional nonlinear Volterra-Fredholm integral equations based on the multi-variate Legendre-collocation *** collocation methods for multi-dimensional nonlinear integral equations are known to cause major difficulties from a convergence analysis point of ***,rigorous error estimates are provided in the weighted Sobolev space showing the exponential decay of the numerical *** existence and uniqueness of the numerical solution are *** experiments are provided to support the theoretical convergence *** results indicate that our spectral collocation method is more flexible with better accuracy than the existing ones.

关键词： spectral collocation method convergence analysis multi-dimensional integral equations

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Solar thermochemical reactions Ⅱ:Synthesis of 2-aminothiophenes via Gewald reaction induced by solar thermal energy

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Chinese Chemical Letters 2008年第7期19卷 788-790页

作者： Ramadan Ahmed Mekheimer Mohamed Abdallah ameen Kamal Usef Sadek Chemistry Department Faculty of ScienceEl-Minia UniversityEl-Minia 61519Egypt

Green conditions have been developed for the synthesis of substituted 2-aminothiophenes employing multicomponent reactions of a ketone with active methylene nitrile and elemental sulphur induced by free solar thermal ... 详细信息

关键词： 2-Aminothiophenes Gewald reaction Solar thermal energy

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Early therapeutic effect of platelet-rich fibrin combined with allogeneic bone marrow-derived stem cells on rats’ critical-sized mandibular defects

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World Journal of Stem Cells 2020年第1期12卷 55-69页

作者： Muhammad A Awadeen Fouad A Al-Belasy Laila E ameen Mohamad E Helal Mohammed E Grawish Department of Oral Biology Faculty of Oral and Dental MedicineDelta University for Science and TechnologyMansoura 11152Egypt Department of Oral Surgery and Anesthesia Faculty of Oral and Dental MedicineDelta University for Science and TechnologyMansoura 11152Egypt Department of Oral Biology Faculty of DentistryMansoura UniversityMansoura 35516Egypt

BACKGROUND Critically sized bone defects represent a significant challenge to orthopaedic surgeons *** defects generally result from severe trauma or resection of a whole large *** bone grafts are the current gold standard for the reconstruction of such ***,due to increased patient morbidity and the need for a second operative site,other lines of treatment should be *** find alternative unconventional therapies to manage such defects,bone tissue engineering using a combination of suitable bioactive factors,cells,and biocompatible scaffolds offers a promising new approach for bone *** To evaluate the healing capacity of platelet-rich fibrin(PRF)membranes seeded with allogeneic mesenchymal bone marrow-derived stem cells(BMSCs)on critically sized mandibular defects in a rat *** Sixty-three Sprague Dawley rats were subjected to bilateral bone defects of critical size in the mandibles created by a 5-mm diameter trephine *** were allocated to three equal groups of 21 rats *** I bone defects were irrigated with normal saline and designed as negative *** of group II were grafted with PRF membranes and served as positive controls,while defects of group III were grafted with PRF membranes seeded with allogeneic *** rats from each group were killed at 1,2 and 4 *** mandibles were dissected and prepared for routine haematoxylin and eosin(HE)staining,Masson's trichrome staining and CD68 immunohistochemical *** Four weeks postoperatively,the percentage area of newly formed bone was significantly higher in group III(0.88±0.02)than in groups I(0.02±0.00)and II(0.60±0.02).The amount of granulation tissue formation was lower in group III(0.12±0.02)than in groups I(0.20±0.02)and II(0.40±0.02).The number of inflammatory cells was lower in group III(0.29±0.03)than in groups I(4.82±0.08)and II(3.09±0.07).CONCLUSION Bone regenerative quality of critically sized mandibula

关键词： Platelet-rich fibrin membrane Bone marrow-derived stem cells Critical-sized mandibular defects Rats Histological and immunohistochemical staining

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Synthesis of thiopyrano[4″,3″:4′,5′]pyrido[3′,2′:4,5]furo[3,2-d]pyrimidines

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Chinese Chemical Letters 2010年第6期21卷 669-673页

作者： Essam Kh. Ahmed Mohamed A. ameen Chemistry Department Faculty of ScienceEl Minia UniversityEl Minia 61519Egypt

Reactions of the 6-hydroxy-thiopyrano[3,4-c]pyridine-5-carbonitrile derivative 1 withα-halo-carbonyl compounds gave the ortho-substituted intermediates 2a-c which were converted into furo[2,3-b]thiopyrano[4,3-d]pyridines 3a-c by fusion of a furan moiety under basic *** cyclization of 3a-c led to a fusion of a pyrimidine ring,yielding the tetracyclic products 6,7 and *** addition,condensation of 6 with various aromatic aldehydes afforded the corresponding imines 9a,*** reaction of 7 gave products 10a,b.

关键词： S N-Heterocycles S N O-Heterocyles Furo[2 3-b]thiopyrano[4 3-d]pyridine Thiopyranopyridofuropyrimidines

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Global Effect of COVID-19 Pandemic on Cancer Patients and its Treatment:A Systematic Review

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Clinical Complementary Medicine and Pharmacology 2022年第4期2卷 12-25页

作者： Mohammad Ali Shahid Ud Din Wani Mubashir Hussain Masoodi Nisar Ahmad Khan H.G.Shivakumar Riyaz MAli Osmani Khalid Ahmed Khan Department of Pharmacology Al-Ameen College of PharmacyBangalore 560001India Department of Pharmaceutical Sciences School of Applied Science and TechnologyUniversity of KashmirSrinagar 190006India College of Pharmacy JSS Academy of Technical EducationNoida 201301India Department of Pharmaceutics JSS College of PharmacyJSS Academy of Higher Education and ResearchMysuru 570015India Assistant Drugs Controller Drugs Control DepartmentGovernment of KarnatakaBengaluruKarnataka 560004India

Background:At a global level,the COVID-19 disease outbreak has had a major impact on health services and has induced disruption in routine care of health institutions,exposing cancer patients to severe *** provide unin-terrupted tumor treatment throughout a pandemic lockdown is a major *** disease(COVID-19)and its causative virus,SARS-CoV-2,stance considerable challenges for the management of oncology ***-19 presents particularly severe respiratory and systemic infection in aging and immunosuppressed indi-viduals,including patients with ***:In the present review,we focused on emergent evidence from cancer sufferers that have been con-taminated with COVID-19 and cancer patients who were at higher risk of severe COVID-19,and indicates that anticancer treatment may either rise COVID-19 susceptibility or have a duple therapeutic impact on cancer as well as COVID-19;moreover,how SARS-CoV-2 infection impacts cancer ***,to assess the global effect of the COVID-19 disease outbreak on cancer and its ***:A literature survey was conducted using PubMed,Web of Science(WOS),Embase,Cochrane Library,China National Knowledge Infrastructure(CNKI),and VIral Protein domain DataBase(VIP DB)between Dec 1,2019 and Sep 23,2021,for studies on anticancer treatments in patients with *** characteristics of the patients,treatment types,mortality,and other additional outcomes were extracted and pooled for ***:This disease has a huge effect on sufferers who have cancer(s).Sufferers of COVID-19 have a greater percentage of tumor diagnoses than the rest of the ***,cancer and highest proportion is lung cancer sufferers are more susceptible to COVID-19 constriction than the rest of the ***:Sufferers who have both COVID-19 and tumor have a considerably elevated death risk than single COVID-19 positive patients *** the COVID-19 pandemic,there was a reduction in the scre

关键词： SARS-CoV-2 Cancer COVID-19 Treatment Chemotherapy

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Modeling,Parameter Measurement,and Control of PMSG-based Grid-connected Wind Energy Conversion System

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Journal of Modern Power Systems and Clean Energy 2021年第5期9卷 1054-1065页

作者： Mohammad Kamruzzaman Khan Prince Graduate Mohammad TArif ameen Gargoom Aman MTOo Md Enamul Haque Renewable Energy&Electric Vehicle(REEV)Lab Centre for Smart Power&Energy Research(cSPER)School of EngineeringDeakin UniversityWaurn pondsAustralia

The design of reliable controllers for wind energy conversion systems(WECSs)requires a dynamic model and accurate parameters of the wind *** this paper,a dynamic model and the parameter measurement and control of a direct-drive variable-speed WECS with a permanent magnet synchronous generator(PMSG)are *** experimental method is developed for measuring the key parameters of the *** measured parameters are used in the design of the *** generator-side converter is controlled using a vector control scheme that maximizes the power extraction under varying wind speeds.A model predictive controller(MPC)is designed for the grid-side voltage source converter(VSC)to regulate the active and reactive power flows to the power grid by controlling the d-and q-axis currents in the synchronous reference *** MPC predicts the future values of the control variables and takes control actions based on the minimum value of the cost *** comply with the grid code requirement,a modified design approach for an LCL filter is presented and incorporated into the *** design process is simple and incorporates significant filter parameters while avoiding iterative *** comparative analysis of the designed filter with conventional L,LC,and iterative LCL filters demonstrates the effectiveness of the modified design *** proposed wind energy system with MPC and LCL filter is simulated in MATLAB/Simulink and experimentally implemented in the laboratory using the dSpace digital signal processor(DSP)*** simulation and experimental results validate the efficacy of the designed controllers using the measured parameters and show dynamic and steady-state performance under varying wind speeds.

关键词： Wind energy permanent magnet synchronous generator(PMSG) parameter measurement model predictive controller(MPC) LCL filter

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Justifying benzoselenadiazole acceptor core as organic semiconductor for stable bulk-heterojunction organic solar cells at ambient temperature

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Journal of Materiomics 2021年第5期7卷 1112-1121页

作者： Abdullah M.Shaheer Akhtar Eun-Bi Kim Hyung-Shik Shin Sadia ameen Advanced Materials and Devices Laboratory Department of Bio-Convergence ScienceJeongeup CampusJeonbuk National University56212Republic of Korea New&Renewable Energy Material Development Center(NewREC) Jeonbuk National UniversityRepublic of Korea Energy Materials&Surface Science Laboratory Solar Energy Research CenterSchool of Chemical EngineeringJeonbuk National University54896Republic of Korea Korea Basic Science Institute(KBSI) 169-148 Gwahak-roYuseong-guDaejon34133Republic of Korea

This work describes the utilization of D-A-D type organic semiconductor,4,4’-(benzo[c][1,2,5]selenadiazole-4,7-diyl)bis(N,N-diphenylaniline),denoted as Se-2TPA,containing benzoselenadiazole(BSe)as acceptor core and end-capped with triphenylamine(TPA)donor units as donor materials in solar ***,the attachment of TPA donor moiety in BSe acceptor unit enlarged the conjugated system by extending the p-bonding which effectively tuned the optical and electrochemical properties of *** bulk heterojunction organic solar cell(BHJ-OSCs)with configuration of ITO/cp-TiO_(2)/Se-2TPA:PC61BM/Au showed power conversion efficiency(PCE)of~4.12% with short circuit current(Jsc)value of~11.28 mA/cm^(2),open circuit voltage(Voc)of~0.775 V and fill factor(FF)of~*** significantly increased from~4.12% to~5.29% when 1,8-diiodooctane(DIO)was added as an additive in Se-2TPA:PC61BM blend which associated with less phase separation and improved the charge *** fabricated BHJ-OSCs processed with 3%DIO,ITO/cp-TiO_(2)/Se-2TPA:PC61BM/Au configuration displayed a long-term stability under air condition at an ambient temperature by maintaining~80% PCE for the duration of 30 *** advantages of easy synthesis,low cost and promising cell performance supported Se-2TPA as successful organic semiconductor for BHJ-OSCs.

关键词： Benzoselenadiazole Thin film Organic semiconductor Stability Organic solar cells

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High-Bandwidth,Low-Power CMOS Transistor Based CAB for Field Programmable Analog Array

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Computers, Materials & Continua 2023年第3期74卷 5885-5900页

作者： ameen Bin Obadi Alaa El-Din Hussein Samir Salem Al-Bawri Kabir Hossain Abdullah Abdulhameed Muzammil Jusoh Thennarasan Sabapathy Ahmed Jamal Abdullah Al-Gburi Mahmoud A.Albreem Advanced Communication Engineering(ACE) Centre of ExcellenceUniversiti Malaysia Perlis(UniMAP)Faculty of Electronic Engineering TechnologyKangar01000Malaysia Electrical Engineering King Fahd University of Petroleum and MineralsDhahranEastern31261Saudi Arabia Space Science Centre Climate Change InstituteUniversiti Kebangsaan MalaysiaBangi43600Malaysia Department of Electronics&Communication Engineering Faculty of Engineering&PetroleumHadhramout UniversityAl-MukallaHadhramout50512Yemen Faculty of Engineering Norwegian University of Science and Technology(NTNU)GjovikN-2815Norway Faculty of Electronic Engineering Technology Universiti Malaysia Perlis(UniMAP)Kampus Alam UniMAP Pauh PutraArau02600Malaysia Department of General Educational Development Faculty of Science and Information Technology(FSIT)Daffodil International UniversityDhaka1207Bangladesh Department of Electronics and Computer Engineering(FKEKK) Center for Telecommunication Research and Innovation(CeTRI)Universiti Teknikal Malaysia Melaka(UTeM)Durian Tungal76100Malaysia Department of Electrical Engineering University of SharjahSharjah27272United Arab Emirates

This article presents an integrated current mode configurable analog block(CAB)system for field-programmable analog array(FPAA).The proposed architecture is based on the complementary metal-oxide semiconductor(CMOS)transistor level design where MOSFET transistors operating in the saturation region are *** proposed CAB architecture is designed to implement six of thewidely used current mode operations in analog processing systems:addition,subtraction,integration,multiplication,division,and pass *** functionality of the proposed CAB is demonstrated through these six operations,where each operation is chosen based on the user’s selection in the CAB interface *** architecture of the CAB system proposes an optimized way of designing and integrating only three functional cells with the interface circuitry to achieve the six ***,optimized programming and digital tuning circuitry are implemented in the architecture to control and interface with the functional ***,these designed programming and tuning circuitries play an essential role in optimizing the performance of the proposed *** of the proposed CMOS Transistor Based CAB system is carried out using Tanner EDA Tools in 0.35μm standard CMOS *** design uses a±1.5 V power supply and results in maximum 3 dB bandwidth of 34.9 MHz and an approximate size of 0.0537 *** demonstrates the advantages of the design over the current state-of-the-art designs presented for comparison in this ***,the proposed design has a clear aspect of simplicity,low power consumption,and high bandwidth operation,which makes it a suitable candidate for mobile telecommunications applications.

关键词： CMOS field programmable analog array configurable analog block current mode circuit

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