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Increased number of symptoms during the acute phase of SARS-CoV-2 infection in athletes is associated with prolonged time to return to full sports performance—AWAREⅧ

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Journal of Sport and Health Science 2024年第3期13卷 280-287,I0001页

作者： Carolette Snyders Marlise Dyer Nicola Sewry Esme Jordaan Martin Schwellnus Sport Exercise Medicine and Lifestyle Institute(SEMLI)Faculty of Health SciencesUniversity of PretoriaPretoria 0083South Africa Section Sports Medicine Faculty of Health SciencesUniversity of PretoriaPretoria 0083South Africa IOC Research Centre of south africa Pretoria 0083South Africa Biostatistics Unit South African Medical Research CouncilTygerberg 7505South Africa Statistics and Population Studies Department University of the Western CapeCape Town 7535South Africa

Purpose The aim of the study was to identify factors associated with prolonged time to return to full performance(RTFP)in athletes with recent severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)*** Prospective cohort study with cross sectional analysis.A total of 84 athletes with confirmed SARS-CoV-2 infection assessed at a coronavirus disease 2019 recovery clinic gave a history of age,sex,type/level of sport,co-morbidities,pre-infection training hours,and 26 acute SARS-CoV-2 symptoms from 3 categories(“nose and throat”,“chest and neck”,and“whole body”/systemic).Data on days to RTFP were obtained by structured *** associated with RTFP were demographics,sport participation,history of co-morbidities,pre-infection training history,and acute symptoms(type,number).Outcomes were:(a)days to RTFP(median,interquartile range(IQR))in asymptomatic(n=7)and symptomatic athletes(n=77),and(b)hazard ratios(HRs;95%confidence interval)for symptomatic athletes with *** a factor(univariate,multiple models).HR0.05).Factors associated with prolonged RTFP(univariate models)were:females(HR=0.57;p=0.014),endurance athletes(HR=0.41;p<0.0001),co-morbidity number(HR=0.75;p=0.001),and respiratory disease history(HR=0.54;p=0.026).In symptomatic athletes,prolonged RTFP(multiple models)was significantly associated with increased“chest and neck”(HR=0.85;p=0.017)and“nose and throat”(HR=0.84;p=0.013)symptoms,but the association was more profound between prolonged RFTP and increased total number of“all symptoms”(HR=0.91;p=0.001)and“whole body”/systemic(HR=0.82;p=0.007)*** A larger number of total symptoms and specifically“whole body”/systemic symptoms during the acute phase of SARS-CoV-2 infection in athletes is associated with prolonged RTFP.

关键词： Athletes COVID-19 Performance Recovery Return to play

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The immune response to SARS-CoV-2 in people with HIV

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Cellular & Molecular Immunology 2024年第2期21卷 184-196页

作者： Maxine A.Höft Wendy A.Burgers Catherine Riou institute of Infectious Disease and Molecular Medicine University of Cape TownCape TownSouth Africa Division of Medical Virology Department of PathologyUniversity of Cape TownCape TownSouth Africa Wellcome Centre for Infectious Diseases Research in africa University of Cape TownCape TownSouth Africa

This review examines the intersection of the HIV and SARS-CoV-2 *** with HIV(PWH)are a heterogeneous group that differ in their degree of immune suppression,immune reconstitution,and viral *** COVID-19 in those with wellcontrolled HIV infection poses no greater risk than that for HIV-uninfected individuals,people with advanced HIV disease are more vulnerable to poor COVID-19 ***-19 vaccines are effective and well tolerated in the majority of PWH,though reduced vaccine efficacy,breakthrough infections and faster waning of vaccine effectiveness have been demonstrated in *** is likely a result of suboptimal humoral and cellular immune responses after *** with advanced HIV may also experience prolonged infection that may give rise to new epidemiologically significant variants,but initiation or resumption of antiretroviral therapy(ART)can effectively clear persistent ***-19 vaccine guidelines reflect these increased risks and recommend prioritization for vaccination and additional booster doses for PWH who are moderately to severely *** recommend continued research and monitoring of PWH with SARS-CoV-2 infection,especially in areas with a high HIV burden.

关键词： SARS-CoV-2 HIV Immune dysfunction Vaccine efficacy Prolonged infection Immunogenicity

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Incidence of respiratory infections and SARS-CoV-2 is higher during contact phases in student rugby players–Lessons learnt from COVID-19 risk mitigation strategies–AWARE V

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Sports Medicine and Health Science 2024年第3期6卷 252-259页

作者： Carolette Snyders Nicola Sewry Wayne Derman Maaike Eken Esme Jordaan Sonja Swanevelder Martin Schwellnus Sport Exercise Medicine and Lifestyle Institute(SEMLI)Faculty of Health SciencesUniversity of PretoriaSouth Africa Section Sports Medicine Faculty of Health SciencesUniversity of PretoriaSouth Africa IOC Research Centre of south africa South Africa institute of Sport and Exercise Medicine Department of ExerciseSport and Lifestyle MedicineFaculty of Medicine and Health SciencesStellenbosch UniversitySouth Africa Biostatistics Unit South African Medical Research CouncilSouth Africa Statistics and Population Studies Department University of the Western CapeSouth Africa

The incidence of acute respiratory infections(ARinf),including SARS-CoV-2,in unvaccinated student rugby players during phases from complete lockdown during the COVID-19 pandemic to returning to competition is *** aim of the study was to determine the incidence of ARinf(including SARS-CoV-2)during noncontact and contact phases during the COVID-19 pandemic to evaluate risk mitigation *** this retrospective cohort study,319 top tier rugby players from 17 universities completed an online *** was reported during 4 phases over 14 months(April 2020–May 2021):phase 1(individual training),phase 2(non-contact team training),phase 3(contact team training)and phase 4(competition).Incidence(per 1000 player days)and Incidence Ratio(IR)for‘All ARinf’,and subgroups(SARS-CoV-2;‘Other ARinf’)are *** factors associated with ARinf were also *** incidence of‘All ARinf’(0.31)was significantly higher for SARS-CoV-2(0.23)vs.‘Other ARinf’(0.08)(p<0.01).The incidence of‘All ARinf’(IR¼3.6;p<0.01)and SARS-CoV-2(IR¼4.2;p<0.01)infection was significantly higher during contact(phases 3þ4)compared with non-contact(phases 1þ2).Demographics,level of sport,co-morbidities,allergies,influenza vaccination,injuries and lifestyle habits were not associated with ARinf *** student rugby,contact phases are associated with a 3–4 times higher incidence of ARinf/SARS-CoV-2 compared to non-contact *** risk mitigation strategies in the contact sport setting are *** from this study serve as a platform to which future research on incidence of ARinf in athletes within contact team sports,can be compared.

关键词： COVID-19 Athletes Risk Prevention Epidemiology

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Assessment of challenges and strategies for driving energy transitions in emerging markets:A socio-technological systems perspective

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Energy Geoscience 2024年第2期5卷 81-100页

作者： Nelson S.Chipangamate Glen T.Nwaila Wits Mining institute University of the Witwatersrand1 Jan Smuts Ave.Johannesburg2000South Africa School of Geosciences University of the WitwatersrandPrivate Bag 3Wits2050South Africa

The pursuit of improved quality of life standards has significantly influenced the contemporary mining model in the 21st *** era is witnessing an unprecedented transformation driven by pressing concerns related to sustainability,climate change,the just energy transition,dynamic operating environments,and complex social *** transitions present both opportunities and *** aim of this study is to provide an extensive literature review on energy transition to identify the challenges and strategies associated with navigating transformations in energy *** these transformations is particularly critical in the face of the severe consequences of global warming,where an accelerated energy transition is viewed as a universal *** a socio-technological systems perspective,specifically through the application of Actor Network Theory(ANT),this research provides a theoretical foundation while categorising challenges into five distinct domains and outlining strategies across these different *** insights are specifically tailored for emerging market countries to effectively navigate energy transition while fostering the development of resilient ***,our findings highlight that energy transition encompasses more than a mere technological shift;it entails fundamental changes in various systemic socio-economic *** focusing on the role of social structures in transitions,this study makes a significant and innovative contribution to ANT,which has historically been criticised for its limited acknowledgement of social ***,we propose an emerging market energy transition framework,which not only addresses technological aspects,but also integrates social *** framework paves the way for future research and exploration of energy transition *** outcomes of this study offer valuable insights to policymakers,researchers,and practitioners engaged in t

关键词： Actor network theory Energy transition Social innovation Technology Actor inclusive policy

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Increasing age and duration of sex work among female sex workers in south africa and implications for HIV incidence estimation:Bayesian evidence synthesis and simulation exercise

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Infectious Disease Modelling 2024年第1期9卷 263-277页

作者： Nanina Anderegg Mariette Slabbert Kholi Buthelezi Leigh F.Johnson Centre for Infectious Disease Epidemiology and Research School of Public HealthUniversity of Cape TownSouth Africa institute of Social and Preventive Medicine University of BernSwitzerland Independent Consultant PretoriaSouth Africa National Sex Workers Movement in South Africa

Introduction:In sub-Saharan africa,accurate estimates of the HIV epidemic in female sex workers are crucial for effective prevention and care *** estimates are typically derived from mathematical models that assume certain demographic and behavioural characteristics like age and duration of sex work to remain constant over *** reviewed this assumption for female sex workers in south ***:We reviewed studies that reported estimates on either the age or the duration of sex work among female sex workers in south *** used Bayesian hierarchical models to synthesize reported estimates and to study time *** a simulation exercise,we also investigated the potential impact of the"constant age and sex work duration"-assumption on estimates of HIV ***:We included 24 different studies,conducted between 1996 and 2019,contributing 42 estimates on female sex worker age and 27 estimates on sex work *** was evidence suggesting an increase in both the duration of sex work and the age of female sex workers over *** to the fitted models,over each decade the expected duration of sex work increased by 55.6%(95%-credible interval[CrI]:23.5%–93.9%)and the expected age of female sex workers increased by 14.3%(95%-CrI:9.1%–19.1%).Over the 23-year period,the predicted mean duration of sex work increased from 2.7 years in 1996 to 7.4 years in 2019,while the predicted mean age increased from 26.4 years to 32.3 *** for these time trends in the simulation exercise resulted in a notable decline in estimated HIV incidence rate among sex workers over *** decline was significantly more pronounced than when assuming a constant age and duration of sex ***:In south africa,age and duration of sex work in female sex workers increased over *** this trend might be influenced by factors like expanding community mobilization and improved rights advocacy,the ongoing criminalisation,stigmatisation of s

关键词： Female sex workers Mathematical modelling south africa HIV

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A hybrid solar-biogas system for post-COVID-19 rural energy access

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Clean Energy 2024年第1期8卷 84-99页

作者： Ochuko K.Overen KeChrist Obileke Edson L Meyer Golden Makaka Oliver O.Apeh Fort Hare institute of Technology University of Fort HarePrivate Bag X1314Alice 5700South Africa Department of Physics Renewable Energy Research CentreUniversity of Fort HarePrivate Bag X1314Alice 5700South Africa Department of Electrical and Electronic Engineering Science Faculty of Engineering and Build EnvironmentUniversity of JohannesburgAuckland Park 2006South Africa

Solar home systems for rural electrification are often designed with a limited energy supply,which presents a drawback for the ***,uncontrolled livestock faeces in rural communities constitute environmental sanitation and health *** excrement can be used through a biogas digester to supplement solar energy to provide adequate and sustainable elec-tricity access to underserved rural communities while achieving waste ***,this study presents a hybrid solar-biogas system for a more dynamic energy supply and waste management for post-Covid recovery plans in rural communities.A parametric research approach that involves the use of the Integrated Environment Solution Virtual Environment software application and mathematical models to design the desired household load and the hybrid system sizing is used in the *** findings show that the daily household energy consumption was 6.6 kWh,equivalent to 206.40 kWh/month.A 1.2-kWp and 1.2-m^(3)hybrid solar-biogas system was found to adequately power the ***,the total initial investment cost of the system was$5777.20 with a net present value of$6566.78,net profit of$4443.6,a payback period of 14 years and 8 months,and a levelized cost of energy of$0.21/kWh;these include a 60%initial investment and maintenance costs *** performance contracting and energy-as-a-service were recommended to effectively run and operate the *** study successfully revealed the design,specifications and upscaling mechanism of the proposed hybrid solar-biogas *** research is required to unveil the efficacy of the system,the performance gap and the perception of the technology by the beneficiaries.

关键词： energy access sustainable rural development clean energy waste management post-COVID-19 recovery plan

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Investigations of nuclear chirality at iThemba LABS

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Frontiers of physics 2024年第2期19卷 7-38页

作者： R.A.Bark E.A.Lawrie C.Liu S.Y.Wang iThemba Laboratory for Accelerator Based Sciences National Research FoundationP.O.Box 722Somerset-West 7129South Africa Department of Physics University of the Western CapePrivate Bag X177535BellvilleSouth Africa Shandong Provincial Key Laboratory of Optical Astronomy and Solar-Terrestrial Environment Institute of Space SciencesShandong UniversityWeihai 264209China

Progress in the studies of chirality in atomic nuclei at iThemba LABS is *** regions of chirality,around mass 80 and 190 have been discovered using the AFRODITE array,specifically in the nuclei^(74)As,^(78,80,82)Br,^(81)Kr,and^(193,194,198)*** phenomena have been observed,including multiple chiral bands in the same nucleus,the coexistence of octupole correlations and nuclear chirality,and the coexistence of pseudo spin and nuclear *** best example of chiral degeneracy to date was found in ^(194)*** level scheme of ^(106)Ag has been revisited and interpreted in terms of two-and four-quasiparticle *** using the particle-rotor model have shown that the fingerprints of chirality in the two-quasiparticle system only can occur in an idealised model *** systems with a higher number of quasiparticles,the calculations showed that nuclear chirality can persist.

关键词： chirality high-spin states particle-rotor model

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Applications of cnoidal and snoidal wave solutions via optimal system of subalgebras for a generalized extended (2+1)-D quantum Zakharov-Kuznetsov equation with power-law nonlinearity in oceanography and ocean engineering

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Journal of Ocean Engineering and Science 2024年第2期9卷 126-153页

作者： Oke Davies Adeyemo International institute for Symmetry Analysis and Mathematical Modelling Department of Mathematical SciencesNorth-West UniversityMafikeng CampusPrivate Bag X 2046Mmabatho 2735Republic of South Africa

The nonlinear evolution equations have a wide range of applications,more precisely in physics,biology,chemistry and engineering *** domain serves as a point of interest to a large extent in the world’s mathematical ***,this paper purveys an analytical study of a generalized extended(2+1)-dimensional quantum Zakharov-Kuznetsov equation with power-law nonlinearity in oceanography and ocean *** Lie group theory of differential equations is utilized to compute an optimal system of one dimension for the Lie algebra of the *** further reduce the equation using the subalgebras ***,more general solutions of the underlying equation are secured for some special cases of n with the use of extended Jacobi function expansion ***,we secure new bounded and unbounded solutions of interest for the equation in various solitonic structures including bright,dark,periodic(cnoidal and snoidal),compact-type as well as singular *** applications of cnoidal and snoidal waves of the model in oceanography and ocean engineering for the first time,are outlined with suitable *** can be of interest to oceanographers and ocean engineers for future ***,to visualize the dynamics of the results found,we present the graphic display of each of the ***,we construct conservation laws of the understudy equation via the application of Noether’s theorem.

关键词： A generalized extended(2+1)-dimensional quantum Zakharov-Kuznetsov equation Lie point symmetries Optimal system of subalgebras Cnoidal and snoidal waves Extended Jacobi function expansion technique Conservation laws

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An overlapping grid spectral collocation analysis on a newly developed hybrid nanofluid flow model

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Propulsion and Power Research 2024年第1期13卷 98-117页

作者： Amir Yaseen Khan Musawenkhosi Patson Mkhatshwa Sabyasachi Mondal Melusi Khumalo Noor Fadiya Mohd Noor Department of Mathematics Amity UniversityKolkataNewtown 700135West BengalIndia Department of Mathematical Sciences University of South AfricaCnr Christian de Wet Rd&Pioneer AvenueFlorida 1709South Africa Department of Mathematics North-Eastern Hill UniversityShillong 793022MeghalayaIndia institute of Mathematical Sciences University of Malaya50603 Kuala LumpurMalaysia

The present study investigates the axisymmetric stagnation point radiativeflow of a Cu-Al2O3/water hybrid nanofluid over a radially stretched/shrunk *** this paper,a new mathematical model has been developed by taking into consideration the concept of different nanoparticles concentration in a hybrid nanofluid,which are Brownian motion and thermophor-esis of nanoparticles.A new model for entropy generation has also been provided in the present *** non-dimensional governing equations of the developed mathematical model are solved using newly developed and efﬁcient overlapping grid spectral collocation *** stability and residual error test are provided here to show the accuracy of the numer-ical method in this mathematical *** outcomes offluidflow,temperature,and two different types of concentration proﬁles are depicted,and described in graphical and tabular *** the limiting instances,comparison shows excellent agreement among current and results established in the *** the strength of magneticﬁeld is seen to increase the radial component offluid velocity as well as the entropy generated within the *** different nanofluid concentration proﬁles are increasing and decreasing with rising thermophor-esis and Brownian motion parameters,respectively,from a particular height above the disk because of the revised nanofluid boundary *** proﬁle increases here with increasing Biot number,and increasing Brinkman number causes higher entropy generation number for both stretching and shrinking *** enhanced thermal characteristics of the hybrid nanofluid over the single particle nanofluid has been observed.ª2024 The *** services by Elsevier *** behalf of KeAi Communications ***.

关键词： Axisymmetricflow Hybrid nanofluid Thermal radiation Overlapping grid method Entropy generation

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Countermeasures to reduce the risk of infections at the 2024 Olympic and Paralympic Games—A balancing act

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Journal of Sport and Health Science 2024年第6期13卷 722-725页

作者： Marcel Jooste Martin Schwellnus Sport Exercise Medicine and Lifestyle Institute(SEMLI)Faculty of Health SciencesUniversity of PretoriaPretoria 0083South Africa Section Sports Medicine Faculty of Health SciencesUniversity of PretoriaPretoria 0083South Africa IOC Research Centre of south africa Pretoria 0083South Africa

The Olympic and Paralympic Games are a global celebration of athletic dedication and achievement,bringing together athletes and spectators from around the ***,such large gatherings present public health challenges for the Organizing Committees and local *** highlighted by the coronavirus disease 2019(COVID-19)pandemic,these events are associated with an increased risk of transmission of infections,which can significantly impact the health and well-being of athletes and *** the health and safety of athletes,officials and spectators is fundamental to ensure the successful hosting of the ***,it is essential to design and implement comprehensive countermeasures to mitigate the risk of an infectious disease outbreak among participants but also to the residents of the host city.

关键词： gathering bringing infections

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