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Severe Klebsiella pneumoniae pneumonia complicated by acute intra-abdominal multiple arterial thrombosis and bacterial embolism:A case report

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World Journal of Clinical Cases 2022年第30期10卷 11101-11110页

作者： Xiao-Li Bao Nan Tang Yang-Zhong Wang Department of Respiratory and Critical Care Medicine Chongqing University Fuling HospitalChongqing 408000China

BACKGROUND Klebsiella pneumoniae(***)is a clinically common Gram-negative bacillus that can cause community-and hospital-acquired infections and lead to pneumonia,liver abscesses,bloodstream infections,and other infectious diseases;however,severe pneumonia caused by hypervirulent ***(hv Kp)complicated by acute intra-abdominal multiple arterial thrombosis and bacterial embolism is rarely seen in the clinical setting and has not been reported in the *** SUMMARY A 51-year-old man was hospitalized with fever and *** mild pain in the middle and upper abdomen began at dawn on the 3rd day following admission and developed into persistent severe pain in the left upper abdomen 8h *** on chest computed tomography(CT),bronchoscopy,bronchoalveolar lavage fluid metagenomic next-generation sequencing,abdominal aortic CT angiography(CTA),and culture of the superior mesenteric artery embolus,adult community-acquired severe hv Kp pneumonia complicated by acute intraabdominal multiple arterial thrombosis and bacterial embolism was ***,he recovered and was discharged from the hospital after receiving effective meropenem anti-infection,endovascular contact thrombolytic,and systemic anticoagulant therapies and undergoing percutaneous thrombus *** days later,the patient returned to the hospital for abdominal CTA examination,which indicated blocked initial common pathway of the celiac trunk and superior mesenteric artery,and local ***,celiac trunk artery stenting was performed in Chongqing Hospital,and postoperative recovery was *** We report a case of hv Kp severe pneumonia complicated by acute intra-abdominal multiple arterial thrombosis and bacterial embolism and suggest that clinicians should consider the possibility of a Gram-negative bacillus infection and conduct effective pathogen detection in a timely fashion when managing patients with severe community-acquired pneumonia befo

关键词： Klebsiella pneumoniae Severe pneumonia Acute mesenteric ischemia Superior mesenteric artery embolism Case report

原位裂口切除加松解治疗陈旧性肛裂80例临床分析

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中国社区医师 2016年第30期32卷 58-58,60页

作者：刘兴涪陵协和医院 408000

目的:探讨原位裂口切除加松解治疗陈旧性肛裂的临床效果。方法:收治陈旧性肛裂患者80例,采用原位裂口切除加松解治疗,观察治疗效果。结果:治疗有效率100%,未发生严重不良并发症。结论:原位裂口切除加松解治疗对陈旧性肛裂患者的临床效... 详细信息

目的:探讨原位裂口切除加松解治疗陈旧性肛裂的临床效果。方法:收治陈旧性肛裂患者80例,采用原位裂口切除加松解治疗,观察治疗效果。结果:治疗有效率100%,未发生严重不良并发症。结论:原位裂口切除加松解治疗对陈旧性肛裂患者的临床效果显著。

关键词：陈旧性肛裂原位裂口切除松解治疗

Resonance Rayleigh scattering study of the interaction of bleomycinA_5 with nucleic acids and its analytical application

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Science China Chemistry 2007年第5期50卷 629-637页

作者： LIU JiangTao1,2, LIU ZhongFang1 & LIU ShaoPu1 1 School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China 2 Department of Chemistry, Fuling Normal University, Chongqing 408000, China School of Chemistry and Chemical Engineering Southwest UniversityChongqing400715China Department of Chemistry Fuling Normal UniversityChongqing 408000China

The interaction of bleomycinA5 with nucleic acids has been investigated byusing resonance Rayleigh scattering (RRS),molecular absorption and fluorescence *** resultshows that in near pH 2.2 buffer medium and absence of any metal ions,nucleic acids are capable ofbinding with bleomycinA5 (BLMA5) to form complexes which can remarkably enhance the RRS intensityand result in batho-chromic and hyperchromic molecular absorption of nucleic acids and fluorescencequenching of *** RRS spectral characteristics for the binding products of bleomycinA5with various DNA and RNA are similar,and the maximum RRS peaks are at 301 nm for ctDNA and sDNA,370nm for hsDNA,310 nm for RNAtypeVI and RNAtypelll,*** increments of RRS intensity aregreatly different in which DNA enhances greatly and RNA enhances *** this work,the optimumconditions of the interaction and some influencing factors have been *** reactionmechanism and a binding model for the interaction of BLMA5 with the nucleic acids are ***,a highly sensitive,simple and rapid new method for the determination of DNA has *** detection limits (3 sigma) are 5.7 ng/mL for ctDNA,7.4 ng/mL for sDNA and 9.2 ng/mLfor hsDNA,*** method can be applied to determination of trace amounts of DNA.

关键词： bleomycinA5, nucleic acids, resonance Rayleigh scattering, fluorescence quenching, absorption spectrum.

Study on the absorption and fluorescence and resonance Rayleigh scattering spectra of Cu (II)-fluoroquinolone chelates with erythrosine and their applications

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Science China Chemistry 2008年第1期51卷 31-40页

作者： WANG Jian LIU ZhongFang LIU ShaoPu LIU JiangTao SHEN Wei YI AoEr School of Chemistry and Chemical Engineering Southwest China UniversityChongqing 400715China Department of Chemistry Yangtze Normal UniversityChongqing 408000China

In pH 4.2-5.0 Britton-Robinson buffer solution medium, fluoroquinolone antibiotics (FLQs), such as ciprofloxacin (CIP), norfloxacin (NOR), ofloxacin (OF), levofloxacin (LEV), lomefloxacin (LOM), and sparfloxacin (SPA), react with Cu (II) to form chelate cations, which further bind with erythrosine to form the ion association complexes. They can result in the changes of the absorption spectra. Simultane- ously, erythrosine fades obviously and the maximum fading wavelength is located at 526 nm. The fad- ing reactions have high sensitivities. Thus, new spectrophotometries of determination for these drugs are developed. The ion-association reactions result in the quenching of fluorescence, which also have high sensitivities. The detection limits for six antibiotics are in the range of 7.1-12.2 μg·L?1. Furthermore, the reactions can result in the enhancement of resonance Rayleigh scattering (RRS). The maximum scattering peaks of six ion-association complexes are located at 566 nm, and there are two small RRS peaks at 333 nm and 287 nm. The detection limits for fluoroquinolone antibiotics are in the range of 1.70 -3.10 μg·L?1 for RRS method. Among the above three methods, the RRS method has the highest sen- sitivity. In this work, we investigated the spectral characteristics of the absorption, fluorescence and RRS, the optimum conditions of the reactions, and the properties of the analytical chemistry. In addi- tion, the mechanism of reactions were discussed by density function theory (DFT) and AM1 methods.

关键词： fluoroquinolone Cu (II) erythrosine absorption fluorescence resonance Rayleigh scattering spectra

A Highly Sensitive Spectrophotometric Assay of Bleomycins Based on the Fading Reaction of Some Halofluorescein Dyes

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Chinese Journal of Chemistry 2007年第8期25卷 1156-1162页

作者：刘江涛刘忠芳胡小丽孔玲刘绍璞 School of Chemistry and Chemical Engineering Southwest University Chongqing 400715 China Department of Chemistry and Environment Engineering Fuling Normal University Fuling Chongqing 408000 China

In weak acidic medium, anticancer antibiotics bleomycin A5 （BLMA5） and bleomycin A2 （BLMA2） can react with halofluorescein dyes such as erythrosin （Ery）, eosin Y （EY）, eosin B （EB） and rose bengal （RB） by virtue of electrostatic attraction and hydrophobic force to form the ion-association complexes, which can result in the fading reactions of four halofluorescein dyes. The maximum fading wavelengths of these four dyes were located at 527 nm for Ery, 515 nm for EY, 517 nm for EB and 546 nm for RB, respectively. The decrements of absorbance （AA） were directly proportional to the concentrations of bleomycin in a certain range. A new method for the determination of bleomycins anticancer drugs based on fading reactions of halofluorescein dyes has been developed. The method was not only highly sensitive but also simple and rapid. The molar absorptivities （ε） ranged from 1.5 × 10^5 to 7.5 × 10^5 L·mol^-1·cm^-1. It was applied to determination of the bleomycins in human serum, urine and rabbit serum samples. In this work, the spectral properties and the optimum reaction conditions were investigated. The structure of ion-association complexes and the reaction mechanism were discussed.

关键词： spectrophotometry bleomycin As bleomycin A2 halofluorescein dye

Reservoir formation conditions and key exploration & development technoloiges in the Yingdong Oilfield in western Qaidam Basin

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Petroleum Research 2018年第2期3卷 132-151页

作者： Dade Ma Yan Chen Xiaomin Xia Xuebin Wei Yanxiong Wu Li Yuan Liu He PetroChina Qinghai Oilfield Company Gansu736202China Sinopec Chongqing Fuling Shale Gas Exploration and Development Co. Ltd.Chongqing408000China

Located in east part of Yingxiongling structural belt in the Qaidam Basin,the Yingdong oilfield has a extremely complicated ground *** to no significant discovery,this oilfield was considered to have no favorable geologic conditions for formation of oil or gas *** the past few years,with continuous improvement in the mountain 3D seismic surveys and logging data interpretation,some breakthroughs were obtained in 2010,and the Yingdong oilfield,the largest-scale reserves of a single reservoir with highest organic matter abundance,most favorable physical property and optimal development efficiencies in the Qaidam Basin,had been discovered,the production capacity was up to 0.55×10^(6) *** detailed analyses of the Yingdong oilfield,some studies,such as hydrocarbon accumulation conditions and technical challenges,are carried out,and following conclusions can be *** Yingxiongling area is located in Mangya hydrocarbon-generation sag in the west part of the Qaidam Basin,its oil sources are rich;the Neogene Xiayoushashan Formation and Shangyoushashan Formation are dominated by wide and gentle delta frontdshore-shallow lacustrine sediments with interbeds of sandstone and mudstone,the sandbodies are widely distributed with favorable physical condition,and the mudstone is the key caprock,combined with high-quality Paleogene hydrocarbon source rocks,a complete source-reservoir-cap assemblage can be ***-scale detachment faults of the Yingdong area connect high-quality Paleogene hydrocarbon source rocks with middle-shallow buried structural traps,thus,reservoirs formed in the early stage are modified,and at the same time,hydrocarbons formed in the later stage continue to migrate and accumulate;in this way,the deep and shallow faults form a relay-style hydrocarbon transport system,and hydrocarbons are accumulated in the shallow structural traps in the later stage;in this area,the middle-shallow faults have good lateral plugging performance w

关键词： Neotectonic movement Structural traps Faulted block Complex mountain areas High-efficiency development Xiayoushashan Formation and Shangyoushashan Formation Yingdong oilfield Qaidam basin

Magnetic and Electronic Properties of β-Graphyne Doped with Rare-Earth Atoms

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Chinese Physics Letters 2019年第7期36卷 61-65页

作者： Juan Ren Song-Bin Zhang Ping-Ping Liu School of Physics and Information Technology Shaanxi Normal University Xi'an 710119 School of Science Xi'an Technological University Xi'an 710032 College of Materials and Engineering Yangtze Normal University Chongqing 408000

Structural, electronic and magnetic properties of La-, Ce-, Pr-, Nd-, Pm-, Sm-and Eu-doped β-graphyne are investigated by comprehensive ab initio calculation based on density functional theory. The adsorption energies indicate that the dopings are suitable. The doped -graphyne undergoes transition from semiconductor to ***, the doping of Nd, Pm, Sm and Eu atoms can induce magnetization. The results are useful for spintronics and the design of future electronic devices.

关键词： Structural by comprehensive ab electronic devices

对劳动价值理论的学术争论应持严肃、科学和求实的态度──简评余陶生同志的商榷意见

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探索 1997年第6期 78-82,,95,页

作者：曾绪宜中共重庆涪陵市委 408000

Formation mechanism of fault accommodation zones under combined stress in graben basin:Implications from geomechanical modeling

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Petroleum Science 2024年第1期21卷 54-76页

作者： Qi-Qiang Ren Jin-Liang Gao Rong-Tao Jiang Jin Wang Meng-Ping Li Jian-Wei Feng Institute of Sedimentary Geology Chengdu University of TechnologyChengdu 610059SichuanChina PetroChina Research Institute of Petroleum Exploration and Development Beijing100083China Jianghan Oilfield Oil and Gas Production Capacity Construction Management Center Chongqing408000China Sinopec Chongqing Fuling Shale Gas Exploration and Development Company Chongqing408000China College of Energy Chengdu University of TechnologyChengdu 610059SichuanChina School of Geoscience China University of Petroleum(East China)Qingdao 266580ShandongChina

A fault accommodation zone is a type of structure that is defined as regulating displacement and strain between faults *** numbers of fault accommodation zones are being identified in graben basins,indicating the potential exploration target and petroleum accumulation *** study aims to analyze the formation mechanism and development of fault accommodation zones under combined stress by a numerical simulation method considering geomechanical *** three-dimensional(3-D)seismic interpretation and fractal dimension method,exampled with the Dongxin fault zone,the fault activity and fault combination pattern were conducted to quantitatively characterize the activity difference in fault accommodation *** with mechanical experiment test,a geomehcanical model was established for fault accommodation zones in a graben *** the paleostress numerical simulations and structural physical simulation experiment,the developmental characteristics and genetic mechanism of fault accommodation zones were *** by multi movements and combined stresses,three significant tectonic evolution stages of the Dongxing Fault Zone(DXFZ)were distinguished:During the E_(s)^(3)sedimentary period,the large difference in the stress,strain,and rupture distribution in various faults were significant,and this stage was the key generation period for the prototype of the DXFZ,including the FAZ between large-scale *** the E_(s)^(2)sedimentary period,the EW-trending symmetric with opposite dipping normal faults and the NE-SW trending faults with large scale were furtherly *** junction area of two secondary normal faults were prone to be ruptured,performing significant period for inheriting and developing characteristics of fault accommodation *** the Es1 sedimentary period,the high-order faults in the DXFZ exhibited the obvious fault depressions and strike-slip activity,and the fault accommodation zones were

关键词： Fault accommodation zone Graben basin Fault activity Tectonic physical simulation experiment Finite element numerical simulation Dongxin fault zone