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Anti-vascular endothelial growth factor and macular atrophy:an unanswered question

Annals of Eye Science 2018年第1期3卷 403-406页

作者： Adam Wylęgała Edward Wylęgała Department of Ophthalmology Railway HospitalKatowicePoland 2nd school of medicine with the division of dentistry in zabrze medical university of silesia KatowicePoland

Does anti-vascular endothelial growth factor(VEGF)therapy lead to geographic atrophy?If so,does the number of injections or the duration of anti-VEGF therapy correlate with the risk of developing geographic atrophy?With intravitreal injections becoming the most common ophthalmic invasive procedure and an increasingly aging population,these questions really matter.

关键词： atrophy injections therapy

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Environmental exposure to cadmium but not lead is associated with decreased semen quality parameters:quality regionalism of sperm properties

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Asian Journal of Andrology 2022年第1期24卷 26-31页

作者： Katarzyna Olszak-Wasik Andrzej Tukiendorf Aleksandra Kasperczyk Artur Wdowiak Stanislaw Horak Department of Gynecology Obstetrics and Oncological Gynecology in BytomMedical University of SilesiaSchool of Medicine and Division of Dentistry in ZabrzeBatorego 15Bytom 41-902Poland Department of Public Health Wroclaw Medical UniversityBartla 5Wroclaw 51-618Poland Department of Biochemistry Medical University of SilesiaSchool of Medicine and Division of Dentistry in ZabrzeJordana 19Zabrze 41-808Poland Faculty of Health Sciences Diagnostic Techniques UnitMedical University of LublinStaszica 4/6Lublin 20-081Poland

Environmental factors may negatively contribute to a progressive worsening of semen quality,and differences in semen quality may result from different environmental exposures(regional differences)or lifestyle *** metals are factors with a confirmed negative influence on male *** them,lead and cadmium are commonly found in human ***,we analyzed semen parameters(according to the World Health Organization 2010 recommendations)and semen lead and cadmium concentrations in 188 men from two different regions in Poland,a typical agricultural area and an industrial area,in couples that had been diagnosed with *** assays were performed using flameless electrothermal atomic absorption *** the statistical analysis,regional comparisons and then taxonomic comparisons based on three parameters(age,semen concentration,and sperm morphology)were *** showed that more cadmium than lead accumulated in semen,a higher cadmium concentration was observed in semen obtained from men from the agricultural region,and better semen quality and lower cadmium concentrations were found in the semen of men from the industrial,more polluted *** thus showed an existing regionalism in the sperm quality ***,semen parameters such as morphology and progressive and nonprogressive motility followed the same trends,regardless of the patient’s age,region,or *** could conclude that the environment has a minor impact on sperm morphology and progressive and nonprogressive motility and that other existing factors could have an indirect influence on semen quality.

关键词： cadmium environment lead semen quality taxonomic analysis

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Impact of ultrasound and optical biometry on refractive outcomes of cataract surgery after penetrating keratoplasty in keratoconus

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International Journal of Ophthalmology(English edition) 2019年第6期12卷 949-953页

作者： Katarzyna Krysik Anita Lyssek-Boron Dominika Janiszewska-Bil Edward Wylegala Dariusz Dobrowolski Department of Ophthalmology with Pediatric Unit St.Barbara HospitalTrauma CentreSosnowiec 41-200Poland Department of Ophthalmology District Railway HospitalKatowice 40-760Poland Chair and Clinical Department of Ophthalmology School of Medicine with the Division of Dentistry in ZabrzeMedical University of Silesia in KatowiceKatowice 40-760Poland Hebei Provincial Eye Hospital Xingtai 054001Hebei ProvinceChina

AIM: To analyse the impact of ultrasound and optical intraocular lens(IOL) calculation methods on refractive outcomes of cataract phacoemulsification performed after penetrating keratoplasty(PK) in keratoconus. METHODS: Phacoemulsification cataract surgery was performed on 42 eyes of 34 patients with keratoconus who had previously undergone PK. The IOL power was determined by using both standard and corneal topography-derived keratometry using the SRK/T formula. We used two independent methods-ultrasound biometry(UB) and interferometry [optical biometry(OB)] for IOL calculation. The analysed data from medical records included demographics, medical history, best corrected visual acuity(BCVA) on Snellen charts, technique of IOL calculation and calculation formula and its impact on final refractive ***: BCVA ranged from 0.01 to 0.4(mean 0.09±0.19) before surgery and ranged from 0.2 to 0.7(mean 0.38±0.14) at 1 mo and from 0.2 to 1.0(mean 0.56±0.16)(Pnd OB groups(Pnd or OB.

关键词： ultrasound biometry optical biometry cataract surgery penetrating keratoplasty keratoconus

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