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症状性椎-基底动脉硬化和夹层的弥散加权磁共振成像

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世界核心医学期刊文摘（神经病学分册） 2005年第12期1卷 9-9页

作者： Koch S. Amir M. Rabinstein A.A. 高中宝 Dr. Department of Neurology Professional Arts Center University of Miami 1150 NW 14th St Miami FL 33136 United States

Background: Acute multiple brain infarction (AMBI) pattern on diffusion-weighted imaging (DWI) is associated with arterial and cardiac sources of embolism. The DWI characteristics of patients with stroke due to vertebrobasilar arterial dissection and atherosclerotic disease have not been reported in detail. Abstract:Objective: To describe the DWI stroke patterns in patients with posterior circulation occlusive disease to determine mechanisms of ischemia. Design: Retrospective analysis of infarct patterns in patients with symptomatic vertebrobasilar disease. Setting: Large community-based teaching hospital. Patients: Patients admitted with stroke due to vertebrobasilar disease were identified *** were included if DWI was obtained within 7 days of symptom onset. Main Outcome Measure: Infarct patterns were analyzed according to established templates of vascular territories. Results: Eleven patients with vertebral dissection and 39 patients with atherothrombosis were *** AMBI pattern was present in 8 (72%) of 11 patients with arterial dissections and 25 (64%) of 39 patients with atherosclerotic disease (P = .48). Distal embolism to the terminal branches of the basilar artery occurred with equal frequency in both groups and was found in half of all cases. Isolated thalamic infarction did not occur. Pontine infarction was noted in 2 (18%) of 11 patients with dissections and 18 (46%) of 39 patients with atherosclerosis (P = .09). Cerebellar border zone involvement was found in 14 (36%) of 39 patients with atherosclerosis and 4 (37%) of 11 patients with dissections (P = .6). Conclusions: Large arterial disease is frequently associated with AMBI in the posterior circulation. The incidence of AMBI was comparable to that reported in the anterior circulation. This DWI study supports the importance of embolism as the main mechanism of infarction in patients with vertebrobasilar occlusive disease. On the basis of our experience, large-vessel vertebr

关键词：基底动脉心源性栓塞丘脑梗死血管闭塞脑桥梗死弥散加权成像前循环小血管教学医院血栓栓塞

胰岛素样生长因子-1基因剪接变体可作为首次阴道分娩后肛提肌损伤的指标

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世界核心医学期刊文摘（妇产科学分册） 2005年第11期1卷 4-4页

作者： Cortes E. Wong Te Fong L.F. Hameed M. 朱国栋 Academic Department of Obstetrics and Gynaecology Royal Free Hospital Pond St London NW3 2QG United Kingdom Dr.

Objective: studies in animals and human muscle have demonstrated differential splicing of the insulin-like growth factor-1 gene in response to mechanical strain and damage. We conducted a study on the expression of insulin-like growth factor-1 splice variants in the levator ani muscle after the first vaginal delivery. study design: Ten women were recruited after the first vaginal delivery. Biopsy specimens were taken vaginally of the pubovisceral component of the levator ani muscle. Five nonpregnant women were recruited as control subjects. Samples were processed with real-time quantitative polymerase chain reaction, with specific primers for the insulin-like growth factor-1 splice variants. Results: Insulin-like growth factor splice variants mechano growth factor and insulin-like growth factor1Ea were significantly up-regulated (100-and 1000-fold) in the delivery population, compared with control subjects (P = .012 and .04, respectively). statistical analysis indicated a correlation between the expression of the insulin-like growth factor-1 splice variants and the length of the second stage. Conclusion: These results show that damaged levator ani muscle results from stretch and overload after the first vaginal delivery.

关键词：剪接变体阴道分娩肛提肌第二产程非妊娠妇女机械拉伸机械压力生长因子研究设计特异性

The Land- Potential Knowledge System (LandPKS): mobile apps and collaboration for optimizing climate change investments

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Ecosystem Health and Sustainability 2016年第3期2卷 31-38页

作者： Jeffrey E.Herrick Adam Beh Edmundo Barrios Ioana Bouvier Marina Coetzee David Dent Emile Elias Tomislav Hengl Jason W.Karl Hanspeter Liniger John Matuszak Jason CNeff Lilian Wangui Ndungu Michael Obersteiner Keith D.Shepherd Kevin C.Urama Rik van den Bosch Nicholas P.Webb U.S.Department of Agriculture-Agricultural Research Service New Mexico State UniversityJornada Experimental Range MSC 3JERBox 30003Las CrucesNew Mexico 88003-8003 USA World Agroforestry Centre United Nations AvenueGigiriP.O.Box 30677Nairobi00100Kenya U.S.Agency for International Development 3014th StreetSW SA-44(Rm 848)WashingtonD.C.20024 USA Namibia University of Science and Technology 13 Storch StreetPrivate Bag 13388WindhoekNamibia Merchants of Light Ltd Forncett EndNorfolkEngland ISRIC-World Soil information Droevendaalsesteeg 36708PB WageningenThe Netherlands Center for the development and Environment University of BernHallerstrasse 103012BernSwitzerland U.S.Department of state/OES 2201 C St.NWWashingtonD.C.20520USA Environmental studies Program University of Colorado at BoulderCampus Box 397BoulderColorado 80309 USA RCMRD SERVIR-Eastern&Southern AfricaP.O.Box 63200618 RuarakaNairobiKenya International Institute for Applied Systems Analysis Schlossplatz 1 A-2361LaxenburgAustria African Development Bank Avenue Jean-Paul II01 BP 1387Abidjan 01Côte d’Ivoire

Massive investments in climate change mitigation and adaptation are projected during coming *** of these investments will seek to modify how land is *** return on both types of investments can be increased through an understanding of land potential:the potential of the land to support primary production and ecosystem services,and its resilience.A Land-Potential Knowledge System(LandPKS)is being developed and implemented to provide individual users with point-based estimates of land potential based on the integration of simple,geo-tagged user inputs with cloud-based information and *** system will rely on mobile phones for knowledge and information exchange,and use cloud computing to integrate,interpret,and access relevant knowledge and information,including local knowledge about land with similar *** system will initially provide management options based on long-term land potential,which depends on climate,to-pography,and relatively static soil properties,such as soil texture,depth,and *** mod-ules will provide more specific management information based on the status of relatively dynamic soil properties such as organic matter and nutrient content,and of *** paper includes a discus-sion of how this system can be used to help distinguish between meteorological and edaphic drought.

关键词： agriculture analytics crowdsourcing expert systems extension knowledge management land evaluation land-use planning mobile apps sustainability sustainable land management

疱疹性银屑病:银屑病患者发生卡波济水痘样疹3例报道

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世界核心医学期刊文摘（皮肤病学分册） 2005年第10期1卷 7-7页

作者： Santmyire-Rosenberger B.R Nigra T.P 罗素菊 Santmyire-Rosenberger Department of Dermatology Washington Hospital Center 110 Irving St NW #2B44 Washington DC 20010 United States.Dr

Background:Kaposi’s varicelliform eruption (KVE), first described in 1887 by Moritz Kaposi, refers to a disseminated cutaneous infection with herpesvirus type 1 or 2, vaccinia virus, or coxsackievirus A16 in a patient with another underlying dermatosis. When herpesvirus type 1 or 2 is the pathogenic virus, theterm“eczema herpeticum”is used,independent of the underlying dermatologic diagnosis that preceded the eruption. KVE is most often seen in patients with underlying atopic dermatitis, but has also been seen in association with other papulosquamous and acantholytic disorders. However, eczema herpeticum rarely occurs in patients with psoriasis. Observations:We present the clinical and laboratory findings of three patients in whom KVE developed during inpatient hospitalization for a psoriatic flare. These patients each had comorbidities that may have increased susceptibility to KVE. Conclusions:KVE may rarely occur in patients with psoriasis. Erythroderma, systemic sepsis, therapy with immunosuppressant drugs, such as methotrexate and systemic steroids, and therapy with systemic retinoids may possibly increase susceptibility to KVE.

关键词：银屑病卡波疱疹性其他皮肤病泛发性棘层松解异位性皮炎柯萨奇病毒甲氨蝶呤暴发性

医疗卫生保健系统对乳腺癌和宫颈癌妇女的作用

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世界核心医学期刊文摘（妇产科学分册） 2005年第9期1卷 61-61页

作者： Kirsner R.S. Fleming L. 高雪莲 University of Miami/Ve terans Administration Medical Center Department of Dermatology 1201 NW 16th St reet Miami FL 33125 United States Dr.

OBJECTIVE: Two common health care delivery systems in the united states are fe e-for-service and managed care systems, including health maintenance organizat ions (HMOs). Differences may exist in patient outcomes depending upon the health care delivery system in which they are enrolled. We evaluated possible differen ces in the stage at diagnosis for breast and cervical cancer between 2 Medicare health care delivery systems (ie, fee for service and HMO) over the period 1985 -2001. METHODS: We used a linkage of 2 national databases: the Medicare databas e from the Centers for Medicare and Medicaid Services and the National Cancer In stitute’s Surveillance, Epidemiology, and End Results program database to evalu ate differences in stage at diagnosis between HMO and fee for service for breast and cervical cancer. RESULTS: We studied 130,336 Medicare-aged women with brea st cancer (83%Medicare fee for service) and 6,758 women with cervical cancer (8 7%Medicare fee for service). We found an earlier stage of diagnosis for HMO pat ients, which remained significant after adjusting for potential confounding vari ables. Women enrolled in HMOs with breast cancer were 17%more likely and those with cervical cancer 35%more likely to be diagnosed at an in situ stage of diag nosis than fee-for-service patients. It is of note that when women had other c ancer diagnoses, no statistically significant differences were seen in stage at diagnosis for either cancer between fee-for-service and HMO patients. CONCLUSI ON: Differences exist in stage at diagnosis between Medicare patients enrolled i n HMOs compared with fee for service. This is likely due in part to use of or ac cess to care.

关键词：医疗卫生保健医疗保健收费服务原位癌卫生保健系统国家癌症研究所癌症诊断维持组织项目数据库混杂变量

语言或运动短暂性脑缺血发作患者的灌注MRI异常

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世界核心医学期刊文摘（神经病学分册） 2006年第3期2卷 59-59页

作者： Kro A.L. Coutts S.B. Simon J.E. 牛亚利 Seaman Family MR Centre Foothills Hospital 1403 29th St NW Calgary Alta. T2N 2T9 Canada

Background and Purpose -Transient ischemic attack (TIA) patients may deteriorate rapidly. MRI is being increasingly used to assess such patients. One possible mechanism of neurological worsening is the presence of perfusion abnormalities. We sought to identify what proportion of TIA patients had evidence of perfusion abnormalities on MRI. Methods -TIA patients were prospectively enrolled and had a MRI completed as soon as possible. The images were assessed for the presence of perfusion abnormalities. Results -Sixty-nine TIA patients were enrolled, and 62 had perfusion imaging. In 56 patients (81%), the symptoms had resolved before imaging. In 21 patients (33.9%), there was evidence of a perfusion abnorm ality defined by relative mean transit time delay. In 12 patients (19.4%), the perfusion abnormality was present despite having complete resolution of neurological symptoms. We found no relationship between the presence of a perfusion abno rmality and the clinical outcome. Conclusions -A proportion of TIA patients have perfusion abnormalities evident on MRI.

关键词：平均通过时间

Cenozoic tectonic evolution of regional fault systems in the SE Tibetan Plateau

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Science China Earth Sciences 2022年第4期65卷 601-623页

作者： Yang WANG Yuejun WANG Peizhen ZHANG Jinjiang ZHANG Bo ZHANG Jing LIU-ZENG Renjie ZHOU Weitao WANG Huiping ZHANG Zhangjun LI Guangdong Provincial Key Laboratory of Geodynamics and Geohazards School of Earth Sciences and EngineeringSun Yat-Sen UniversityGuangzhou 510275China Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) Zhuhai 519082China The Key Laboratory of Orogenic Belts and Crustal Evolution School of Earth and Space SciencesPeking UniversityBeijing 100871China Institute of Surface-Earth System Science Tianjin UniversityTianjin 300072China School of Earth and Environmental Sciences The University of QueenslandSt Lucia QLD 4072Australia state Key Laboratory of Earthquake Dynamics Institute of GeologyChina Earthquake AdministrationBeijing 100029China

The SE Tibetan Plateau,tectonically situated in the eastern India-Eurasia oblique convergence zone,has experienced multiple stages of deformation since the *** major tectonic boundaries—the Ailaoshan-Red River,ChongshanLincang-Inthanon,and Gaoligong-Mogok shear zones—delineate the first-order tectonic framework in this *** most striking structural features in the block interiors are a series of nw.and NE-trending fault systems,such as the Dayingjiang,Longlin-Ruili,Nantinghe,Red River,Weixi-Qiaohou,and Lancang-Genma faults,which have conjugate geometric *** this study,we review these structures’geometric and kinematic characteristics and deformation histories.A synthesis of existing geological observations,geomorphological analyses,and chronological data reveals three major Cenozoic tectonothermal events,including crustal shortening,strike-slip shearing,and kinematic *** boundary structures controlled the tectonic extrusion of plateau material during the early Oligocene-early *** the mid-late Miocene,nw.and NE-trending fault systems mostly experienced diachronous slip-sense *** onset and spatial trend of regional kinematic reversal are constrained by existing chronologic *** with geophysical and geodetic observations,the activity and geodynamic drivers of the major fault systems and regional deformation styles are explored,revealing that the SE Tibetan Plateau underwent a transition from discrete(lateral block extrusion)to diffuse deformation in the mid-late *** intracontinental crustal deformation and its coupling with dynamic processes at depth during the plateau growth are discussed in the context of the IndiaEurasia convergence.

关键词： Cenozoic SE Tibetan Plateau tectonic boundary conjugate fault system tectonic evolution

结肠和直肠血管肉瘤:1例病例报道和文献回顾

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世界核心医学期刊文摘（胃肠病学分册） 2005年第6期1卷 30-30页

作者： Brown C.J. Falck V.G. MacLean A. 郝筱倩 Department of Surgery Foothills Medical Centre 29th St. NW Calgary Alta. 1403 T2N2T9 Canada Dr.

Angiosarcoma is a malignancy that occurs rarely in the gastrointestinal tract. We present a case of a 77-year-old male who had rectal bleeding and obstructive bowel symptoms. A large near-obstructing mass was seen endoscopically, but biopsies were inconclusive. A CT scan showed a large sigmoid lesion, and the patient had surgical resection. A large hemorrhagic-appearing tumor was found at operation. Angiosarcoma of the sigmoid colon was diagnosed on histologic examination. After colonic resection, the patient rapidly developed numerous liver metastases and died six months later. A review of the literature reveals only 12 other reported cases of colorectal angiosarcoma; 62 percent of these patients died within one year of surgical resection. The role of adjuvant radiation and/or chemotherapy is unclear. In conclusion, colorectal angiosarcomas are rare tumors that behave very aggressively, and the outcome is generally poor.

关键词：血管肉瘤文献回顾肝转移组织学检查肠道梗阻内镜检查侵袭性

Eocene supra-subduction zone mafic magmatism in the Sibumasu Block of SW Yunnan: Implications for Neotethyan subduction and India-Asia collision

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Eocene supra-subduction zone mafic magmatism in the Sibumasu...