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Rethinking the Encoder-decoder Structure in Medical Image Segmentation from Releasing Decoder Structure

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Journal of Bionic Engineering 2024年第3期21卷 1511-1521页

作者： Jiajia Ni Wei Mu An Pan Zhengming Chen School of Artificial Intelligence Anhui Polytechnic UniversityWuhu241000China School of Information Science and Engineering HoHai UniversityChangzhou213000China

Medical image segmentation has witnessed rapid advancements with the emergence of encoder-decoder based *** the encoder-decoder structure,the primary goal of the decoding phase is not only to restore feature map resolution,but also to mitigate the loss of feature information incurred during the encoding ***,this approach gives rise to a challenge:multiple up-sampling operations in the decoder segment result in the loss of feature *** address this challenge,we propose a novel network that removes the decoding structure to reduce feature information loss(CBL-Net).In particular,we introduce a Parallel Pooling Module(PPM)to counteract the feature information loss stemming from conventional and pooling operations during the encoding ***,we incorporate a Multiplexed Dilation Convolution(MDC)module to expand the network's receptive ***,although we have removed the decoding stage,we still need to recover the feature map ***,we introduced the Global Feature Recovery(GFR)*** uses attention mechanism for the image feature map resolution recovery,which can effectively reduce the loss of feature *** conduct extensive experimental evaluations on three publicly available medical image segmentation datasets:DRIVE,CHASEDB and MoNuSeg *** results show that our proposed network outperforms state-of-the-art methods in medical image *** addition,it achieves higher efficiency than the current network of coding and decoding structures by eliminating the decoding component.

关键词： Medical image segmentation Encoder-decoder architecture Attention mechanisms Releasing decoder architecture Neural network

Subclinical impairment of left ventricular myocardium function in type 2 diabetes mellitus patients with or without hypertension

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World Journal of Diabetes 2024年第6期15卷 1272-1279页

作者： Zeng-Guang Chen Guang-An Li Jun Huang Li Fan Department of Cardiology The Affiliated Changzhou Second People’s Hospital with Nanjing Medical UniversityChangzhou 213000Jiangsu ProvinceChina Department of Echocardiography The Affiliated Changzhou Second People’s Hospital with Nanjing Medical UniversityChangzhou 213000Jiangsu ProvinceChina

BACKGROUND Cardiovascular disease has been the leading cause of morbidity and mortality for type 2 diabetes mellitus(T2DM)patients over the last *** To determine whether layer-specific global longitudinal strain(GLS)combined with peak strain dispersion(PSD)can be used to assess left ventricle(LV)myocardium systolic dysfunction in T2DM patients or without hypertension(HP).METHODS We enrolled 97 T2DM patients,70 T2DM+HP patients and 101 healthy ***-specific GLS and PSD were calculated by EchoPAC software in apical three-,four-and two-chamber *** of the epimyocardial,middle-layer and endomyocardial(GLSepi,GLSmid,and GLSendo)were measured and *** operating characteristic analysis was performed to detect LV myocardium systolic dysfunction in T2DM *** There were significant differences in GLSepi,GLSmid,GLSendo,and PSD between healthy subjects,T2DM patients and T2DM patients with HP(PT2DM patients>T2DM with HP patients in the absolute values of GLSepi,GLSmid and GLSendo(P<0.001),while PSD was ranked healthy subjects

关键词： Type 2 diabetes mellitus Hypertension Speckle tracking echocardiography Global longitudinal strain Peak strain dispersion

Evaluation of left ventricular systolic function in type 2 diabetes mellitus patients with and without peripheral vascular disease

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World Journal of Diabetes 2024年第6期15卷 1280-1290页

作者： Guang-An Li Jun Huang Li Fan Department of Echocardiography The Affiliated Changzhou Second People’s Hospital with Nanjing Medical UniversityChangzhou 213000Jiangsu ProvinceChina

BACKGROUND Peripheral vascular disease(PVD)is a common complication of type 2 diabetes mellitus(T2DM).Patients with T2DM have twice the risk of PVD as nondiabetic *** To evaluate left ventricular(LV)systolic function by layer-specific global longitudinal strain(GLS)and peak strain dispersion(PSD)in T2DM patients with and without *** Sixty-five T2DM patients without PVD,57 T2DM patients with PVD and 63 normal controls were enrolled in the ***-specific GLS[GLS of the epimyocardium(GLSepi),GLS of the middle myocardium(GLSmid)and GLS of the endocardium(GLSendo)]and PSD were *** operating characteristic(ROC)analysis was performed to calculate the sensitivity and specificity of LV systolic dysfunction in T2DM patients with *** calculated Pearson’s correlation coefficients between biochemical data,echocardiographic characteristics,and layer-specific GLS and *** There were significant differences in GLSepi,GLSmid and GLSendo between normal controls,T2DM patients without PVD and T2DM patients with PVD(PT2DM patients without PVD>T2DM patients with PVD in the absolute value of GLS(P<0.001).PSD differed significantly between the three groups,and the trend ranking was as follows:normal controls

关键词： Type 2 diabetes mellitus Peripheral vascular disease Speckle tracking echocardiography Global longitudinal strain Peak strain dispersion

Endoscopic ultrasound-guided biliary drainage vs percutaneous transhepatic bile duct drainage in the management of malignant obstructive jaundice

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1592-1600页

作者： Qin-Qin Zhu Bing-Fang Chen Yue Yang Xue-Yong Zuo Wen-Hui Liu Ting-Ting Wang Yin Zhang Department of Gastroenterology The Third Affiliated Hospital of Soochow University(The First People’s Hospital of Changzhou)Changzhou 213000Jiangsu ProvinceChina Department of Hepatobiliary and Pancreatic Surgery The Third Affiliated Hospital of Soochow University(The First People’s Hospital of Changzhou)Changzhou 213000Jiangsu ProvinceChina

BACKGROUND Malignant obstructive jaundice(MOJ)is a condition characterized by varying degrees of bile duct stenosis and obstruction,accompanied by the progressive development of malignant tumors,leading to high morbidity and mortality ***,the two most commonly employed methods for its management are percutaneous transhepatic bile duct drainage(PTBD)and endoscopic ultrasound-guided biliary drainage(EUS-BD).While both methods have demonstrated favorable outcomes,additional research needs to be performed to determine their relative *** compare the therapeutic effectiveness of EUS-BD and PTBD in treating *** This retrospective analysis,conducted between September 2015 and April 2023 at The Third Affiliated Hospital of Soochow University(The First People’s Hospital of Changzhou),involved 68 patients with *** patients were divided into two groups on the basis of surgical procedure received:EUS-BD subgroup(n=33)and PTBD subgroup(n=35).Variables such as general data,preoperative and postoperative indices,blood routine,liver function indices,myocardial function indices,operative success rate,clinical effectiveness,and complication rate were analyzed and compared between the *** In the EUS-BD subgroup,hospital stay duration,bile drainage volume,effective catheter time,and clinical effect-iveness rate were superior to those in the PTBD subgroup,although the differences were not statistically significant(P>0.05).The puncture time for the EUS-BD subgroup was shorter than that for the PTBD subgroup(P<0.05).Postoperative blood routine,liver function index,and myocardial function index in the EUS-BD subgroup were significantly lower than those in the PTBD subgroup(P<0.05).Additionally,the complication rate in the EUS-BD subgroup was lower than in the PTBD subgroup(P<0.05).CONCLUSION EUS-BD may reduce the number of punctures,improve liver and myocardial functions,alleviate traumatic stress,and decrease complication rates in MOJ treatment

关键词： Percutaneous hepatic biliary drainage Endoscopic ultrasound-guided biliary drainage Malignant obstructive jaundice Clinical effect Liver function Postoperative complications

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髓内骨延长治疗儿童下肢不等长的研究进展

中华小儿外科杂志 2024年第8期45卷 763-768页

作者：高志鹏路真郭海滨杨港贺早南通大学附属常州儿童医院骨科常州213000

下肢不等长对于小儿骨科医生是一个极具挑战性的课题,可引起跛行、背痛、髋关节发育不良及脊柱侧弯等问题。传统的外固定架延长术存在许多并发症,如关节僵硬、肌肉挛缩、针道感染以及给不适体验感。目前髓内肢体延长术已经成为外固定装... 详细信息

下肢不等长对于小儿骨科医生是一个极具挑战性的课题,可引起跛行、背痛、髋关节发育不良及脊柱侧弯等问题。传统的外固定架延长术存在许多并发症,如关节僵硬、肌肉挛缩、针道感染以及给不适体验感。目前髓内肢体延长术已经成为外固定装置之外的一个有价值的选择,可以消除临床上对于外固定装置的依赖性和减少并发症。本研究综述髓内延长装置临床应用经验,以期为儿童下肢畸形的矫正提供以参考。

关键词：骨延长术下肢畸形髓内钉儿童

高散热铝背板光伏组件的设计及其工作温度的研究

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太阳能学报 2024年第3期45卷 549-554页

作者：孙爱祥魏青竹姬明良陈进永臻科技股份有限公司常州213000

以铝板作为光伏组件的背板材料,从绝缘安全性角度进行组件设计,并对铝背板组件工作温度性能进行研究。结果表明,铝背板组件通过做整版隔离,组件绝缘性能满足IEC 61215-2021标准,且散热性优异,实验结果与理论模拟匹配。

关键词：铝板光伏组件绝缘散热背板材料

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LiF/GAP协同作用改善硼粉的燃烧性能

火炸药学报 2024年第3期47卷 279-286,I0006页

作者：伍双艳王吉权邵建刘俊陈九玉朱宝忠孙运兰常州大学石油与天然气工程学院·能源学院江苏常州213000

以氟化锂/缩水甘油叠氮化物聚合物(LiF/GAP)为界面层对微米硼进行改性,研究LiF/GAP协同作用对硼粉热行为、燃烧性能和凝聚相燃烧产物的影响。结果表明,通过硅烷偶联剂处理后,硼粉表面黏结性得以提高,LiF能够较好地包覆在硼粉表面;GAP在... 详细信息

以氟化锂/缩水甘油叠氮化物聚合物(LiF/GAP)为界面层对微米硼进行改性,研究LiF/GAP协同作用对硼粉热行为、燃烧性能和凝聚相燃烧产物的影响。结果表明,通过硅烷偶联剂处理后,硼粉表面黏结性得以提高,LiF能够较好地包覆在硼粉表面;GAP在400℃之前抑制了LiF与硼表面氧化膜的反应,使LiF的除膜效应延后至硼粉氧化增重阶段,从而将更多的活性硼暴露在空气中发生氧化,促进了硼粉的燃烧;LiF和GAP协同作用显著改善了硼粉的燃烧性能,尤其当LiF和GAP质量分数均为10%时,作用效果最为明显。此外,LiF和GAP协同作用有效抑制了燃烧过程中硼粉团聚,使其凝聚相燃烧产物粒径降低。

关键词：物理化学硼颗粒 LiF/GAP协同作用燃烧特性团聚抑制燃烧机理

Emerging roles and therapeutic potentials of sphingolipids in pathophysiology:emphasis on fatty acyl heterogeneity

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Journal of Genetics and Genomics 2024年第3期51卷 268-278页

作者： Jinming Mu Sin Man Lam Guanghou Shui State Key Laboratory of Molecular Developmental Biology Institute of Genetics and Developmental BiologyChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100101China Lipidall Technologies Company Limited ChangzhouJiangsu 213000China

Sphingolipids not only exert structural roles in cellular membranes,but also act as signaling molecules in various physiological and pathological processes.A myriad of studies have shown that abnormal levels of sphingolipids and their metabolic enzymes are associated with a variety of human ***,blood sphingolipids can also be used as biomarkers for disease *** review summarizes the biosynthesis,metabolism,and pathological roles of sphingolipids,with emphasis on the biosynthesis of ceramide,the precursor for the biosynthesis of complex sphingolipids with different fatty acyl *** possibility of using sphingolipids for disease prediction,diagnosis,and treatment is also *** endogenous ceramides and complex sphingolipids along with their specific fatty acyl chain to promote future drug development will also be discussed.

关键词： Sphingolipids Ceramide Therapeutic targets Microdomain Biomarker

基于节点路径重构和ELM的无线通信网络DDoS攻击源追踪

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现代电子技术 2024年第13期47卷 93-96页

作者：方欲晓何可人常州大学江苏常州213000

在无线通信网络中,DDoS攻击通常涉及大量的攻击者和恶意节点,并以多种形式发起攻击。攻击流量经过中间节点和反射/放大攻击等技术手段后变得更加复杂,追踪其溯源路径和确定唯一的攻击源变得复杂。为此,文中研究基于节点路径重构和ELM的... 详细信息

在无线通信网络中,DDoS攻击通常涉及大量的攻击者和恶意节点,并以多种形式发起攻击。攻击流量经过中间节点和反射/放大攻击等技术手段后变得更加复杂,追踪其溯源路径和确定唯一的攻击源变得复杂。为此,文中研究基于节点路径重构和ELM的无线通信网络DDoS攻击源追踪方法。通过正则化方式优化ELM的参数,检测获取DDoS攻击数据包;采用路由器标记算法标记DDoS攻击数据包,在无线通信网络域间重构攻击节点路径,获取DDoS攻击源位置,完成无线通信网络DDoS攻击源追踪。实验结果证明:文中方法可精准检测获取DDoS攻击数据包,并完成攻击数据包的标记,且可有效重构攻击节点路径,追踪到DDoS攻击源。

关键词：节点路径重构 ELM 无线通信网络 DDoS攻击源正则化攻击数据包路由器标记自治系统