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抗中性白细胞胞浆抗体相关性肾脏病：肾脏病...

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中华肾脏病杂志 1992年第3期8卷 180-182页

作者：刘志红黎磊石 210002

狼疮性肾炎中西医结合治疗研究：附196例分析

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中华肾脏病杂志 1992年第3期8卷 137-140页

作者：蒋炜黎磊石 210002

本文对经肾活检证实并长期坚持随访的196例狼疮性肾炎的近、远期疗效及其药物的副作用进行了观察，并对影响疗效的诸因素作了分析。治疗分激素组（Ⅰ组），激素加雷公藤组（Ⅱ组），环磷酰胺加激素加雷公藤组（Ⅲ组）。结果显示Ⅱ、Ⅲ... 详细信息

本文对经肾活检证实并长期坚持随访的196例狼疮性肾炎的近、远期疗效及其药物的副作用进行了观察，并对影响疗效的诸因素作了分析。治疗分激素组（Ⅰ组），激素加雷公藤组（Ⅱ组），环磷酰胺加激素加雷公藤组（Ⅲ组）。结果显示Ⅱ、Ⅲ组疗效明显优于Ⅰ组及文献报道，而治疗中的副作用亦明显减少，采用中西医结合的综合疗法对控制狼疮活动，减少维持治疗时的激素用量均有重要意义。

关键词：狼疮性肾炎中西医结合

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老年及老年前期肾活检120例分析

中华肾脏病杂志 1992年第3期8卷 146-148页

作者：陈惠萍张景红 210002

Predictive performance of'Diprifusor'TCI system in patients during upper abdominal surgery under propofol/fentanyl anesthesia

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2005年第1期6卷 43-48页

作者：李玉红徐建红杨建军田婕徐建国 Department of Anesthesiology.First Affiliated Hospital School of Medicine Zhejiang UniversityHangzhou310003China Department of Anesthesiology Nanjing Jinling HospitalNanjing210002China Department of Anesthesiology Nanjing Jinlin HospitalNanjing210002China

Objective:To evaluate the predictive performance of‘Diprifusor’TCI(target-controlled infusion)system for its betterapplication in clinical ***:The predictive performance of a‘Diprifusor’TCI system was investigated in 27Chinese patients(16 males and 11 females)during upper abdominal surgery under total intravenous anesthesia(TIVA)withpropofol/*** arterial propofol concentrations were compared with the values predicted by the TCI infusion *** was determined by the median performance error(MDPE),the median absolute performance error(MDAPE),thedivergence(the percentage change of the absolute PE with time),and the wobble(the median absolute deviation of each PE fromthe MDPE).Results:The median(range)values of 14.9%(-21.6%～42.9%)for MDPE,23.3%(6.9%～62.5%)for MDAPE,-1.9%h^(-1)(-32.7%～23.0% h^(-1))for divergence,and 18.9%(4.2%～59.6%)for wobble were obtained from 227 samples from all *** the studied population,the PE did not increase with time but with increasing target propofol concentration,particularly fol-lowing ***:The control of depth of anaesthesia was good in all patients undergoing upper abdominal surgicaloperation and the predictive performance of the‘Diprifusor’target controlled mthsion system was considered acceptable forclinical *** the relatively bigger wobble showed that the pharmacokinetic model is not so suitable and requires im-provement.

关键词： Target-controlled infusion(TCI) ‘Diprifusor’TC1 system Predictive performance assessment Wobble Infusion

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血液透析长期存活的临床研究

中华肾脏病杂志 1992年第1期8卷 11-13页

作者：季大玺肖申 210002

本文回顾性研究了1985年4月前开始血液透析（HD）的43例慢性肾衰（CRF）。发现长期存活与透析前年龄小、早期透析、尿素/肌酐比值小于25，营养良好及心血管并发症少有关。本组存活大于5年者13例，5年存活率52%。还对HD的远期疗效，以及... 详细信息

本文回顾性研究了1985年4月前开始血液透析（HD）的43例慢性肾衰（CRF）。发现长期存活与透析前年龄小、早期透析、尿素/肌酐比值小于25，营养良好及心血管并发症少有关。本组存活大于5年者13例，5年存活率52%。还对HD的远期疗效，以及并发症进行了探讨。

关键词：肾衰竭血液透析存活率

CORAL AS A CARRIER FOR RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN-2

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Chinese Medical Sciences Journal 1999年第2期14卷 125-128页

作者：张森林毛天球孟昭业王会信 DepartmentofStomatology NanjingGeneralHospitalofPLANanjing210002 DepartmentofMaxillofacialSurgery StomatologicalCollegetheFourthMilitaryMedicalUniversityXian InstituteoftheBasicMedicalSciences AcademyofMilitaryMedicalSciencesBeijing

By combining coral with recombinant human bone morphogenetic protein-2 (rhBMP-2), rhBMP-2/coral composite was obtained in this study. Following implantation of the composite into the muscle pouches of mice, cartilage growth was induced in the pores or on the surface of the implants at one week, woven bone at three week and lamellar bone with bone marrow at six week, and coral was absorbed partially. The induced formation of endochondral bone was time-related and rhBMP-2 dose-related. The results of this study indicate that the composite possesses a superior ability of osteogenesis, and coral acts as one of the most suitable rhBMP-2 slowrelease carriers currently available. The composite will be a new type of bone substitute to be used in orthopaedics and maxillofacial surgery.

关键词： recombinant human bone morphogenetic protein 2 osteoinduction carrier

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狼疮性肾炎尿酸化功能测定的临床意义

中华肾脏病杂志 1992年第1期8卷 29-30页

作者：唐政黎磊石 210002

Effects of soy isoflavone extracts on the growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in ovariectomized nude mice

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Chinese Science Bulletin 2009年第1期54卷 72-77页

作者： WU Qian JIN NianZu YU Jing ZHAO RenChen YU ZePing QIAO ShanLei LU XiaoHe ZHANG ChunWen Department of Hygienic Analysis and Detection School of Public Health Nanjing Medical University Nanjing 210029 Research Institute of General Surgery Nanjing General Hospital of PLA Nanjing Military Command Nanjing 210002 Department of Pharmacy Nanjing General Hospital of PLA Nanjing Military Command Nanjing 210002

In this study,we explored the effects of soy isoflavone extracts on the growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in ovariectomized athymic mice. The ovariectomized athymic mice were implanted with MCF-7 cells. They were fed with low,moderate and high doses of soy isoflavone extracts,at dietary concentrations of 6.25,12.5 and 25 g/kg,respectively. The expression of ki-67 was detected by immunohistochemistry. The pS2 expression in tumors was analyzed by real-time PCR. Estrogen level in the serum was measured by chemiluminescence enzyme immunoassay. Com-pared with the control group,dietary soy isoflavone extracts had a significant stimulatory effect on MCF-7 tumor growth in mice (P 0.05). In conclusion,in the tested dietary concentration range soy isoflavone extracts had a stimulatory effect on tumor growth. 6.25 and 12.5 g/kg doses of soy isoflavone extracts can increase the cell proliferation in tumors and induce estrogen-responsive pS2 expression.

关键词：大豆异黄酮提取物乳腺癌裸鼠 MCF-7 雌激素

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见于我国的杜波型组织胞浆菌病

中华皮肤科杂志 1991年第6期24卷 413-415,T002页

作者：张长法郭宁如 210002

组织胞浆菌病分美洲型和非洲型两种,分别由荚膜组织胞浆菌(Histoplasma capsulatum)和杜波型组织胞浆菌(Histoplasmadoboisii)所引起.

关键词：杜波型组织胞浆菌病组织胞浆菌素