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Si-substrate vertical-structure InGaN/GaN micro-LED-based photodetector for beyond 10 Gbps visible light communication

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Photonics Research 2022年第10期10卷 2394-2404页

作者： JIANYANG SHI ZENGYI XU WENQING NIU DONG LI XIAOMING WU ZIWEI LI JUNWEN ZHANG CHAO SHEN GUANGXU WANG XIAOLAN WANG JIANLI ZHANG FENGYI JIANG SHAOHUA YU NAN CHI Key Laboratory for Information Science of Electromagnetic Waves(MoE) Fudan UniversityShanghai 200433China shanghai engineering Research {2. of Low-Earth-Orbit Satellite Communication and Applications Shanghai 200433China shanghai Collaborative Innovation center of Low-Earth-Orbit Satellite Communication Technology Shanghai 200433China national Institute of LED on Silicon Substrate Nanchang UniversityNanchang 330096China Peng Cheng Laboratory Shenzhen 518055China

Visible light communication(VLC)has emerged as a promising communication method in ***,the development of receiving devices is much slower than that of transmitting devices,limited by materials,structures,and *** this paper,we propose and fabricate an InGaN/GaN multiple-quantum-well-based vertical-structure micro-LED-based photodetector(μPD)on a Si substrate.A comprehensive comparison of the photoelectrical performance and communication performance of three sizes ofμPDs,10,50,and 100μm,is *** peak responsivity of all threeμPDs is achieved at 400 nm,while the passband full-widths at half maxima are 87,72.and 78 nm for 10,50,and 100μmμPDs,***−2. dB cutoff bandwidth is up to 82. MHz for 50μmμPD.A data rate of 10.14 Gbps is experimentally demonstrated by bit and power loading discrete multitone modulation and the proposed digital pre-equalizer algorithm over 1 m free space utilizing the self-designed 4×450μmμPD array as a receiver and a 450 nm laser diode as a *** is the first time a more than 10 Gbps VLC system has been achieved utilizing a GaN-based micro-PD,to the best of our *** investigation fully demonstrates the superiority of Si substrates and vertical structures in InGaN/GaNμPDs and shows its great potential for high-speed VLC links beyond 10 Gbps.

关键词： communication beyond utilizing

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Highly stable lithium anode enabled by self-assembled monolayer of dihexadecanoalkyl phosphate

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Nano Research 2020年第5期13卷 1324-1331页

作者： Lei Zheng Feng Guo Tuo Kang Jin Yang Ya Liu Wei Gu Yanfei Zhao Hongzhen Lin Yanbin Shen Wei Lu Liwei Chen School of Nano Technology and Nano Bionics University of Science and Technology of ChinaHefei 230026China i-Lab CAS Center for Excellence in NanoscienceSuzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of SciencesSuzhou 215123China Vacuum Interconnected Nanotech Workstation(Nano-X) Suzhou Institute of Nano-Tech and Nano-Bionics(SINANO)Chinses Academy of Science(CAS)Suzhou 215123China In-situ center for Physical Sciences School of Chemistry and Chemical EngineeringShanghai Jiaotong UniversityShanghai 200240China

Li has been considered as the ultimate anode material for high energy density secondary Li ***,its practical application has been limited due to its low Coulombic efficiency(CE)and the formation of lithium ***,we have developed a microspherical Li-carbon nanotube(Li-CNT)composite material passivated with octadecylphosphonic acid(OPA)self-assembled monolayer(SAM)exhibiting suppressed lithium dendrite formation and improved environmental/electrochemical *** this work,we demonstrated the significantly enhanced passivation effects of a SAM using dihexadecanoalkyl phosphate(DHP),a molecule that is comprised of double hydrophobic alkyl chains and forms a denser SAM on surfaces with large *** a result,the DHP SAM delivers superior environmental and electrochemical stability to the OPA passivated Li-CNT *** specific,the DHP passivated Li-CNT composite(DHP-Li-CNT)delivers a high CE of 99.2.%under a 33.3%depth of discharge(DOD)at 1 C,when it is paired with a LiFePO4 *** evolution of the SAM during cycling and the effects of DOD and current density on the CE of the DHP-Li-CNT anode have also been *** improved SAM passivation constitutes an important step in achieving the goal of practically applicable Li anodes.

关键词： Li metal anode Li-CNT self-assembled monolayer depth of discharge Coulombic efficiency

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Adsorption and Diffusion Properties of Ethylene, Benzene and Ethylbenzene in the Cylindrical Pore under Alkylation Reaction near Critical Regions by DCV-GCMD Simulation

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Chinese Journal of Chemical engineering 2005年第3期13卷 303-312页

作者：刘涛刘洪来袁渭康 UNILAB Research center of Chemical engineeringState Key Laboratory of Chemical Reaction engineering East China University of Science and TechnologyShanghai 200237China

Abstract A cylindrical pore model was used to represent approximately the pore of β-zeolite catalyst that had been used in the alkylation of benzene with ethylene and spherical Lennard-Jones molecules represented the components of the reaction system-ethylene, benzene and ethylbenzene. The dual control volume-grand canonical molecular dynamics (DCV-GCMD) method was used to simulate the adsorption and transport properties of three components under reaction in the cylindrical pore at 2.0℃ and 2.0℃ in the pressure range from 1 MPa to 8 MPa. The state map of the reactant mixture in the bulk phase could be divided into several different regions around its critical points. The simulated adsorption and transport properties in the pore were compared between the different near-critical regions. The thorough analysis suggested that the high pressure liquid region is the most suitable region for the alkylation reaction of benzene under the near-critical condition.

关键词： molecular simulation DCV-GCMD simulation alkylation reaction adsorption diffusion

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Generation of longitudinally polarized multi-segment optical needles by tightly focusing RPBG beam

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光电子快报:英文版 2023年第7期19卷 399-404页

作者： SHI Changkun SONG Yiding DONG Bing ZHOU Zhanqi ZHANG Zengqi XU Zongwei State Key Laboratory of Precision Measuring Technology&Instruments Tianjin UniversityTianjin 300072China School of Optical-Electrical and Computer engineering University of Shanghai for Science and TechnologyShanghai 200093China

In this paper,an effective method to garner sub-wavelength longitudinally polarized multi-segment optical needle sequence by using a specially designed hybrid filter(HF) in a high numerical aperture(NA) objective focusing system is *** HF is coupled by a binary phase transmission function and a multi-segment modulation function,and the binary phase filter is designed by the particle swarm optimization(PSO) algorithm and acts on the radially polarized Bessel Gaussian(RPBG) beam to obtain a longitudinally polarized optical needle with long depth of focus(DOF,6λ) and a sub-wavelength transverse spot size(0.430λ).The optical needle is with high uniformity of 98% and high beam quality of 96%,and the negligible sidelobe is 15%.On this basis,the multi-segment optical needle sequence with tunable spacing or number can be realized by the multi-segment modulation *** is found that the HF makes the generation of multi-segment optical needle sequence more flexible and *** research has broad application prospects in material processing,particle acceleration,particle capture and other fields.

关键词： function polarized beam

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The gut microbiome and microbial metabolites in acute myocardial infarction

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Journal of Genetics and Genomics 2022年第6期49卷 569-578页

作者： Chenglin Liu Zhonghan Sun Shalaimaiti Shali Zhendong Mei Shufu Chang Hanjun Mo Lili Xu Yanni Pu Huihui Guan Guo-Chong Chen Qibin Qi Zhexue Quan Ji Qi Kang Yao Yuxiang Dai Yan Zheng Junbo Ge State Key Laboratory of Genetic engineering School of Life Sciences and Human Phenome InstituteFudan UniversityShanghai 200433China Ministry of Education Key Laboratory of Contemporary Anthropology Fudan UniversityShanghai 200433China Department of Cardiology Shanghai Institute of Cardiovascular DiseaseZhongshan HospitalFudan University1609 Xietu RoadShanghai 200032China Department of Epidemiology and Population Health Albert Einstein College of MedicineBronxNY 10461USA Ministry of Education Key Laboratory for Biodiversity Science and Ecological engineering Institute of Biodiversity ScienceSchool of Life SciencesFudan UniversityShanghai 200433China

Emerging evidence has highlighted the role of gut microbiome in human ***,the integrative role of gut microbiome and microbial metabolites in acute myocardial infarction(AMI)remains *** current study profiles the microbial community through 16S rRNA gene sequencing and shotgun metagenomic sequencing and measures fecal short-chain fatty acids and circulating choline pathway metabolites among 117 new-onset AMI cases and 78 *** microbial alternations are observed in AMI patients compared with controls(P=0.001).The abundances of nine species(e.g.,Streptococcus salivarius and Klebsiella pneumoniae)are positively associated,and one species(Roseburia hominis)is inversely associated with AMI status and severity.A gut microbial score at disease onset is associated with the risk of major adverse cardiovascular events in 3.2.years(hazard ratio[95%CI]:2.01[1.04-4.2.])in AMI *** molar proportions of fecal acetate and butyrate are higher,and the circulating levels of choline and carnitine are lower in AMI patients than in *** addition,disease classifiers show that AMI cases and controls have a more distinct pattern in taxonomical composition than in pathways or *** findings suggest that microbial composition and functional potentials are associated with AMI status and severity.

关键词： Acute myocardial infarction Atherosclerosis Microbiome Short-chain fatty acids

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Long-term ex vivo monitoring of in vivo microRNA activity in liver using a secreted luciferase sensor

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Science China(Life Sciences) 2011年第5期54卷 418-425页

作者： WANG Gang DONG XiaoYan HU JianYang TIAN WenHong YUCHI Jie WANG Yue WU XiaoBing State Key Laboratory of Molecular Virology and Genetic engineering National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and Prevention Beijing 100052 China State Key Laboratory of Genetic engineering Institute of Genetics School of Life Sciences Fudan University Shanghai 200433 China Beijing FivePlus Molecular Medicine Institute Beijing 100176 China Department of Hepatobiliary Surgery Affiliated Hospital of Ningxia Medical University Yinchuan 750004 China

Technology for monitoring in vivo microRNA (miRNA) activity is extremely important for elucidating miRNA ***,in vivo studies of miRNA have been hampered by the lack of a convenient approach to reliably reflect real-time functional changes in *** for miRNA were developed by adding miRNA target sequences to the 3'-untranslated region of Gaussia princeps luciferase (Gluc) *** sensors were then evaluated in vitro and in vivo by measuring Gluc activity in cell supernatants and in peripheral *** driven by the CMV promoter were effective for monitoring miR-12. in living cells,but not for the long-term monitoring of miR-12. or miR-142.in mouse liver because of CMV-promoter *** the CMV promoter with a CAG promoter rendered these sensors effective for the long-term monitoring of relevant liver miRNA *** subsequently used the CAG-promoter-based sensor for the long-term monitoring of endogenous liver miR-12.,miR142.and miR-34a activities,as well as for exogenous miR-34a *** study demonstrates that real-time in vivo activities of miRNAs can be continuously and conveniently detected in mouse liver using the sensors that we have developed.

关键词： microRNA sensor secreted Gaussia luciferase ex vivo monitoring

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首发精神病患者与健康对照组额叶腹内侧Y-氨基丁酸浓度的比较（英文）

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上海精神医学 2015年第6期27卷 341-347页

作者：杨志磊朱雅靖宋振华梅力张建业陈天意王颖婵徐一峰江开达李瑶刘登堂 First-episode Schizophrenia and Early Psychosis Program Division of Psychotic Disorders Shanghai Mental Health Center Shanghai Jiao Tong University School of Medicine shanghai Jiading District Mental Health center School of Biomedical engineering Shanghai Jiao Tong University shanghai Hongkou District Mental Health center

背景：大脑中γ-氨基丁酸（γ-aminobutyric acid,GABA）的浓度和功能异常不仅是精神分裂症的一个重要病因学假说,而且也可能与认知功能下降和精神分裂症阴性症状相关。运用高场强磁共振波谱分析（magnetic resonance spectroscopy,MRS... 详细信息

背景：大脑中γ-氨基丁酸（γ-aminobutyric acid,GABA）的浓度和功能异常不仅是精神分裂症的一个重要病因学假说,而且也可能与认知功能下降和精神分裂症阴性症状相关。运用高场强磁共振波谱分析（magnetic resonance spectroscopy,MRS）的研究发现慢性精神分裂症患者额叶腹内侧（ventromedial prefrontal cortex,vmP FC）的GABA异常浓度,但患者既往使用抗精神病药物可能会对这些结果产生混杂。目标：比较首发精神病患者和健康对照组vmP FC中的GABA浓度,并评估vmP FC中GABA浓度与精神病性症状严重程度之间的关系。方法：共纳入2.例首发精神病患者（10例精神分裂症患者和12.精神分裂样障碍患者）和2.名健康对照者,应用单体素^1H-MRS来检测vmP FC中的GABA和其它代谢产物的浓度。2.例患者中13例患者没有用过药物,9例患者使用抗精神病药物少于3天。采用阳性和阴性症状量表（the Positive and Negative Syndrome Scale,PANSS）评估患者组的精神病症状严重程度。结果：患者组vmP FC的GABA浓度的均值（SD）显著高于对照组（2.2.[0.54]v.1.93[0.32.mM,t=2.62.p=0.012.。其它代谢产物的浓度——包括N-乙酰天冬氨酸（N-acetylaspartic acid,NAA）、谷氨酸（glutamic acid,GLU）和谷氨酰胺（glutamine,GLN）,在患者组和对照组之间没有显著差异。患者vmP FC中的GABA浓度与PANSS总分或三个PANSS分量表（阳性症状、阴性症状、一般精神病理）中的任何一个评分之间没有显著相关性。GABA浓度与病程之间无相关性,但与患者年龄显著相关（r=0.47,p=0.02.）。结论：首发精神病患者vmP FC中的GABA浓度升高证实了该异常情况与药物使用是相互独立的。我们需要更大规模的研究来证实vmP FC中的GABA浓度与精神病症状严重程度之间不存在相关性,但这也提示脑部病理变化与临床症状之间存在若干个中间环节。

关键词：首发精神病首发精神分裂症未经药物治疗磁共振波谱 Y-氨基丁酸额叶腹内侧中国

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An Algorithm for Ship Wake Detection from the SAR Images Using the Radon Transform and Morphological Image Processing

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Journal of Systems engineering and Electronics 2001年第4期12卷 7-12页

作者：金亚秋王世庆 center for Wave Scattering and Remote Sensing School of Information Science and Technology Fudan University Shanghai 200433 P. R. China

Using the Radon transform and morphological image processing, an algorithm for ship's wake detection in the SAR (synthetic aperture radar) image is developed. Being manipulated in the Radon space to invert the gray-level and binary images, the linear texture of ship wake in oceanic clutter can be well detected. It has been applied to the automatic detection of a moving ship from the SEASAT SAR image. The results show that this algorithm is well robust in a strong noisy background and is not very sensitive to the threshold parameter and the working window size.

关键词： Algorithms Image processing Mathematical transformations Radar clutter Radar target recognition Spurious signal noise Synthetic aperture radar

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A new paradigm for artesunate anticancer function:considerably enhancing the cytotoxicity via conjugating artesunate with aptamer

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Signal Transduction and Targeted Therapy 2021年第10期6卷 2964-2966页

作者： Yingying Li Yongbo Peng Yan Tan Wenjing Xuan Ting Fu Xue-Qiang Wang Weihong Tan Molecular Science and Biomedicine Laboratory(MBL) State Key Laboratory of Chemo/Bio-Sensing and ChemometricsCollege of Chemistry and Chemical EngineeringCollege of BiologyAptamer Engineering Center of Hunan ProvinceHunan UniversityChangshaPR China Institute of Molecular Medicine(IMM) Renji HospitalShanghai Jiao Tong University School of Medicineand College of Chemistry and Chemical EngineeringShanghai Jiao Tong UniversityShanghaiPR China The Cancer Hospital of the University of Chinese Academy of Sciences(Zhejiang Cancer Hospital) Institute of Basic Medicine and Cancer(IBMC)Chinese Academy of SciencesHangzhouZhejiangChina

Dear Editor,Artemisinin and its derivatives(AIDs)have recently been widely applied in cancer therapy as promising therapeutic agents owing to its hypotoxicity and special bioactivation *** numerous strategies have been established to improve the potency of AIDs,they are still relatively inefficacious against cancers,especially as a monotherapy.^(1)It is thus essential to develop novel approaches to considerably enhance their anticancer *** hypothesized that aptamers with specific recognition,high-affinity binding,and receptor-mediated internalization would promote the accumulation of AIDs inside the target cells and lead to death of the target cancer cells.^(2.

关键词： artesunate considerably cytotoxicity

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Chronic spinal cord injury repair by NT3-chitosan only occurs after clearance of the lesion scar

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Signal Transduction and Targeted Therapy 2022年第7期7卷 2568-2580页

作者： Can Zhao Jia-Sheng Rao Hongmei Duan Peng Hao Junkui Shang Yubo Fan Wen Zhao Yudan Gao Zhaoyang Yang Yi Eve Sun Xiaoguang Li Beijing Key Laboratory for Biomaterials and Neural Regeneration Beijing Advanced Innovation Center for Biomedical EngineeringSchool of Biological Science and Medical EngineeringBeihang UniversityBeijing 100083China Institute of Rehabilitation engineering China Rehabilitation Science InstituteBeijing 100068China Department of Neurobiology School of Basic Medical SciencesCapital Medical UniversityBeijing 100069China Beijing Advanced Innovation Centre for Biomedical engineering Key Laboratory for Biomechanics and Mechanobiology of Chinese Education MinistrySchool of Biological Science and Medical EngineeringBeihang UniversityBeijing 10083China School of engineering Medicine Beihang UniversityBeijing 10083China shanghai Institute of Stem Cell Research and Clinical Translation Shanghai East HospitalTongji University School of MedicineShanghai 200120China Department of Psychiatry and Biobehavioral Sciences UCLA Medical SchoolLos AngelesCA 90095USA

Spinal cord injury(SCI)is a severe damage usually leading to limb dysesthesia,motor dysfunction,and other physiological *** have previously shown that NT3-chitosan could trigger an acute SCI repairment in rats and non-human *** to the negative effect of inhibitory molecules in glial scar on axonal regeneration,however,the role of NT3-chitosan in the treatment of chronic SCI remains *** with the fresh wound of acute SCI,how to handle the lesion core and glial scars is a major issue related to chronic-SCI *** we report,in a chronic complete SCI rat model,establishment of magnetic resonancediffusion tensor imaging(MR-DTI)methods to monitor spatial and temporal changes of the lesion area,which matched well with anatomical *** of the lesion core via suction of cystic tissues and trimming of solid scar tissues before introducing NT3-chitosan using either a rigid tubular scaffold or a soft gel form led to robust neural regeneration,which interconnected the severed ascending and descending axons and accompanied with electrophysiological and motor functional *** contrast,cystic tissue extraction without scar trimming followed by NT3-chitosan injection,resulted in little,if any *** together,after lesion core clearance,NT3-chitosan can be used to enable chronic-SCI repair and MR-DTI-based mapping of lesion area and monitoring of ongoing regeneration can potentially be implemented in clinical studies for subacute/chronic-SCI repair.

关键词： scar NT3 wound

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