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Constraints on the Distortion of Area Objects in the Process of Map Objects Displacement

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Geo-Spatial Information Science 2009年第2期12卷 117-122页

作者：毛建华曾齐红刘学锋 Research center of Remote Sensing and Spatial Information Science School of Communication and Information Engineering Shanghai University

The displacement operator is an important and still a hot topic in map generalization. In the generalization product, symbols must be unambiguous and easily perceived and readily understood, which makes space competition among features an important obstacle in the process of map objects displacement. Space conflict between objects, through propagation process, may be spread and more objects may drift into it. In order to maintain symbols equilibrium and spatial relationship between objects, some unimportant symbols or parts of symbols should be distorted under constraints according to visual graphic resolution thresholds to figure out space competition among map features. Three constraints including position, legibility and characteristics are important for the maintenance of symbols equilibrium and spatial relationship, which are discussed in this paper. The skeleton is introduced to represent area objects figure characteristic, in which an area object can be separated to parts hierarchically according to their importance in the construction. Then, the finite element method is applied to the map objects’ displacement and distortion, in which a strategy for the parameters of finite element method is discussed.

关键词： map objects displacement constraints object distortion finite element method

Metal-Organic Framework Nanocarriers for Drug Delivery in Biomedical Applications

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Nano-Micro Letters 2020年第8期12卷 184-212页

作者： Yujia Sun Liwei Zheng Yu Yang Xu Qian Ting Fu Xiaowei Li Zunyi Yang He Yan Cheng Cui Weihong Tan Molecular Science and Biomedicine Laboratory(MBL) State Key Laboratory of Chemo/Biosensing and ChemometricsCollege of Chemistry and Chemical EngineeringCollege of BiologyAptamer Engineering Center of Hunan ProvinceHunan UniversityChangsha 410082People’s Republic of China center for Research at Bio/Nano Interface Department of Chemistry and Department of Physiology and Functional GenomicsUF Health Cancer CenterUF Genetics Institute and McKnight Brain InstituteUniversity of FloridaGainesvilleFL 32611USA Department of Electrical engineering Stanford UniversityStanfordCA 94305USA Institute of Molecular Medicine(IMM) Renji HospitalState Key Laboratory of Oncogenes and Related GenesShanghai Jiao Tong University School of Medicine and College of Chemistry and Chemical EngineeringShanghai Jiao Tong UniversityShanghai 200240People’s Republic of China Institute of Cancer and Basic Medicine(IBMC) Chinese Academy of SciencesThe Cancer Hospital of the University of Chinese Academy of SciencesHangzhou 310022People’s Republic of China Foundation for Applied Molecular Evolution 13709 Progress BoulevardAlachuaFL 32615USA

Investigation of metal–organic frameworks(MOFs)for biomedical applications has attracted much attention in recent *** are regarded as a promising class of nanocarriers for drug delivery owing to well-defined structure,ultrahigh surface area and porosity,tunable pore size,and easy chemical *** this review,the unique properties of MOFs and their advantages as nanocarriers for drug delivery in biomedical applications were discussed in the first ***,state-ofthe-art strategies to functionalize MOFs with therapeutic agents were summarized,including surface adsorption,pore encapsulation,covalent binding,and functional molecules as building *** the third section,the most recent biological applications of MOFs for intracellular delivery of drugs,proteins,and nucleic acids,especially aptamers,were ***,challenges and prospects were comprehensively discussed to provide context for future development of MOFs as efficient drug delivery systems.

关键词： Metal-organic frameworks Drugs Biomolecules Drug delivery Biomedical applications

High-resolution X-ray flash radiography of Ti characteristic lines with multilayer Kirkpatrick–Baez microscope at the Shenguang-ⅡUpdate laser facility

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High Power Laser Science and engineering 2021年第3期9卷 61-67页

作者： Shengzhen Yi Feng Zhang Qiushi Huang Lai Wei Yuqiu Gu Zhanshan Wang MOE Key Laboratory of Advanced Micro-Structured Materials Tongji UniversityShanghai 200092China School of Physics Science and engineering Tongji UniversityShanghai 200092China Research center of Laser Fusion China Academy of Engineering PhysicsMianyang 621900China

High-resolution X-ray flash radiography of Ti characteristic lines with a multilayer Kirkpatrick-Baez microscope was developed on the Shenguang-Ⅱ(SG-Ⅱ)Update laser *** microscope uses an optimized multilayer design of Co/C and W/C stacks to obtain a high reflection efficiency of the Ti characteristic lines while meeting the precise alignment requirement at the Cu Kα *** alignment method based on dual simulated balls was proposed herein,which simultaneously realizes an accurate indication of the center field of view and the backlighter *** optical design,multilayer coatings,and alignment method of the microscope and the experimental result of Ti flash radiography of the Au-coned CH shell target on the SG-Ⅱ Update are described.

关键词： flash radiography Kirkpatrick-Baez microscope plasma diagnostics X-ray imaging X-ray multilayer

Ligand engineering in Tin-Based Perovskite Solar Cells

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Nano-Micro Letters 2023年第10期15卷 112-150页

作者： Peizhou Li Xiangrong Cao Jingrui Li Bo Jiao Xun Hou Feng Hao Zhijun Ning Zuqiang Bian Jun Xi Liming Ding Zhaoxin Wu Hua Dong Key Laboratory for Physical Electronics and Devices(MoE) Shaanxi Key Lab of Information Photonic TechniqueSchool of Electronic and Information EngineeringXi’an Jiaotong UniversityXi’an 710049People’s Republic of China center for Excellence in Nanoscience(CAS) Key Laboratory of Nanosystem and Hierarchical Fabrication(CAS)National Center for Nanoscience and TechnologyBeijing 100190People’s Republic of China School of Materials and Energy University of Electronic Science and Technology of ChinaChengdu 611731People’s Republic of China School of Physical Science and Technology ShanghaiTech UniversityShanghai 201210People’s Republic of China Beijing national Laboratory for Molecular Sciences State Key Laboratory of Rare Earth Materials Chemistry and ApplicationsCollege of Chemistry and Molecular EngineeringPeking UniversityBeijing 100871People’s Republic of China Collaborative Innovation center of Extreme Optics Shanxi UniversityTaiyuan 030006People’s Republic of China

Perovskite solar cells(PSCs)have attracted aggressive attention in the photovoltaic field in light of the rapid increasing power conversion ***,their large-scale application and commercialization are limited by the toxicity issue of lead(Pb).Among all the lead-free perovskites,tin(Sn)-based perovskites have shown potential due to their low toxicity,ideal bandgap structure,high carrier mobility,and long hot carrier *** progress of Sn-based PSCs has been realized in recent years,and the certified efficiency has now reached over 14%.Nevertheless,this record still falls far behind the theoretical *** is likely due to the uncontrolled nucleation states and pronounced Sn(Ⅳ)*** insights into the methodologies resolving both issues,ligand engineering-assisted perovskite film fabrication dictates the state-of-the-art Sn-based ***,we summarize the role of ligand engineering during each state of film fabrication,ranging from the starting precursors to the ending fabricated *** incorporation of ligands to suppress Sn~(2.)oxidation,passivate bulk defects,optimize crystal orientation,and improve stability is discussed,***,the remained challenges and perspectives toward advancing the performance of Sn-based PSCs are *** expect this review can draw a clear roadmap to facilitate Sn-based PSCs via ligand engineering.

关键词： Perovskite Solar cells Lead-free Ligand engineering Defects Stability

Spatial and Temporal Variations in the Atmospheric Age Distribution of Primary and Secondary Inorganic Aerosols in China

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engineering 2023年第9期28卷 117-129页

作者： Xiaodong Xie Qi Ying Hongliang Zhang Jianlin Hu Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control Collaborative Innovation Center of Atmospheric Environment and Equipment TechnologyNanjing University of Information Science&TechnologyNanjing 210044China Zachry Department of Civil engineering Texas A&M UniversityCollege StationTX 77843USA Department of Environmental Science and engineering Fudan UniversityShanghai 200438China

The aging timescale of particles is a key parameter in determining their impacts on air quality,human health,and *** this study,a one-year simulation of the age distributions of the primary and secondary inorganic fine particulate matter(PM_(2.5))components was conducted over China using an age-resolved Community Multiscale Air Quality(CMAQ)*** results indicate that primary PM_(2.5)(PPM)and ammonium mainly originate from fresh local emissions,with approximately 60%-80%concentrated in 0-2. h age bins in most of China throughout the *** average age is about15-2. h in most regions in summer,but increases to 40-50 h in southern region of China and the Sichuan Basin(SCB)in *** is more aged than PPM,indicating an enhanced contribution from regional *** sulfate with atmospheric age>48 h account for 30%-50%of total sulfate in most regions and seasons,and the concentrations in the>96 h age bin can reach up to 15μg·m-3 in SCB during *** seasonal variations occur in the Yangtze River Delta,Pearl River Delta,and SCB,with highest average age of 60-70 h in winter and lowest of 40-45 h in *** average age of nitrate is 2.-30 h in summer and increases to 40-50 h in *** enhanced deposition rate of nitric acid vapor combined with the faster chemical reaction rate of nitrogen oxides leads to a lower atmospheric age in ***,on pollution days,the contributions of old age bins(>2. h)increase notably for both PPM and secondary inorganic aerosols in most cities and seasons,suggesting that regional transport plays a vital role during haze *** age information of PM_(2.5),provided by the age-resolved CMAQ model,can help policymakers design effective emergent emission control measures to eliminate severe haze episodes.

关键词： Atmospheric age PM_(2.5) CMAQ model Control strategy

CDP-GAN:Near-Infrared and Visible Image Fusion Via Color Distribution Preserved GAN

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IEEE/CAA Journal of Automatica Sinica 2022年第9期9卷 1698-1701页

作者： Jun Chen Kangle Wu Yang Yu Linbo Luo the School of Automation Hubei Key Laboratory of Advanced Control and Intelligent Automation for Complex SystemsEngineering Research Center of Intelligent Technology for Geo-ExplorationMinistry of EducationChina University of GeosciencesWuhan 430074China the shanghai Institute of Technical Physics Key Laboratory of Infrared System Detecting and Imaging TechnologyChinese Academy of SciencesShanghai 200083China the School of Mechanical engineering and Electronic Information China University of GeosciencesWuhan 430074China

Dear Editor,This letter is concerned with dealing with the great discrepancy between near-infrared(NIR)and visible(VS)image fusion via color distribution preserved generative adversarial network(CDP-GAN).Different from the global discriminator in prior GAN,conflict of preserving NIR details and VS color is resolved by introducing an attention guidance mechanism into the ***。

关键词： details dealing preserving

Current status and perspectives of regulatory T cell-based therapy

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Journal of Genetics and Genomics 2022年第7期49卷 599-611页

作者： Guojun Qu Jieqiong Chen Yangyang Li Yaqin Yuan Rui Liang Bin Li shanghai Institute of Immunology Department of Immunology and MicrobiologyShanghai Jiao Tong University School of MedicineShanghai Jiao Tong UniversityShanghai 200025China shanghai Affinity Biopharmaceutical Co. Ltd.781 Cailun RoadShanghai 201203China Unit of Immune and Metabolic Regulation School of Life Science and TechnologyShanghaiTech UniversityShanghai 201210China

The CD4FOXP3regulatory T(Treg)cells are essential for maintaining immune homeostasis in healthy *** from clinical trials of Treg cell-based therapies in patients with graft versus host disease(GVHD),type 1 diabetes(T1D),liver transplantation,and kidney transplantation have demonstrated that adoptive transfer of Treg cells is emerging as a promising strategy to promote immune *** we provide an overview of recent progresses and current challenges of Treg cell-based *** summarize the completed and ongoing clinical trials with human Treg ***,a few of the chimeric antigen receptor(CAR)-Treg cell therapies are currently undergoing clinical ***,we describe the new strategies for engineering Treg cells used in preclinical ***,we envision that the use of novel synthetic receptors,metabolic regulators,combined therapies,and in vivo generated antigen-specific or engineered Treg cells through the delivery of modified mRNA and CRISPR-based gene editing will further promote the advances of next-generation Treg cell therapies.

关键词： Regulatory T cell FOXP3 Chimeric antigen receptor Cell therapy CRISPR-Based gene editing mRNA-based therapy

Synergistic effect of lithiophilic Zn nanoparticles and N-doping for stable Li metal anodes

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Journal of Energy Chemistry 2022年第2期31卷 439-447页

作者： Lei You Shunlong Ju Jianwen Liu Guanglin Xia Zaiping Guo Xuebin Yu Department of Materials Science Fudan UniversityShanghai 200433China Hubei Collaborative Innovation center for Advanced Organic Chemical Materials Ministry-of-Education Key Laboratory for Synthesis and Applications of Organic Functional MoleculesCollege of Chemistry and Chemical EngineeringHubei UniversityWuhan 430062HubeiChina School of Chemical engineering&Advanced Materials The University of AdelaideAdelaideSA 5005Australia

Li metal is the most ideal anode material for next-generation high energy lithium-ion *** uncontrollable growth of Li dendrites,however,hinders its practical ***,we propose the adoption of Zn nanoparticles uniformly embedded in N-doped carbon polyhedra homogeneously built on carbon cloth(Zn@NC@CC)to prevent the formation of Li *** on theoretical calculation and experimental observation,lithiophilic Zn nanoparticles and N-doping inside of the assynthesized Zn@NC play a synergistic role in enhancing the adsorption capacity with Li,thus resulting in uniform Li deposition and complete suppression of Li ***,the porous N-doped carbon polyhedras uniformly distributed on carbon cloth effectively relieves the volume change of Li upon repeated Li stripping/plating process,which contributes to preserving the structural integrity of the whole electrode and hence enhancing its long-term cycling *** from these synergistic effects,the Li-Zn@NC@CC electrode delivers a prolonged lifespan of over 12.0 h at 1 mA cm^(-2. with an areal capacity of 1 mA h cm^(-2. in symmetric cells and high Coulombic efficiencies of 95.4%under an ultrahigh capacity of 12.mA h cm^(-2..Remarkably,Li-Zn@NC@CC//LiFePO_(4) full cells deliver a high reversible capacity of 110.2.mA h g^(-1) at 1 C over 2.0 cycles.

关键词： Li metal anodes Zn nanoparticles N-doping Synergistic effect

Performance assessment of borehole arrangements for the design of rectangular shallow foundation systems

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Journal of Rock Mechanics and Geotechnical engineering 2023年第12期15卷 3291-3304页

作者： Marcin Chwała Danko J.Jerez Hector A.Jensen Michael Beer Wrocław University of Science and Technology Poland Institute for Risk and Reliability Leibniz University HannoverGermany Departamento de Obras Civiles Universidad Técnica Federico Santa MaríaChile International Joint Research center for Resilient Infrastructure&International Joint Research center for engineering Reliability and Stochastic Mechanics Tongji UniversityShanghai200092China Institute for Risk and Uncertainty and School of engineering University of LiverpoolUnited Kingdom

This study proposes a framework to evaluate the performance of borehole arrangements for the design of rectangular shallow foundation systems under spatially variable soil conditions. Performance measures are introduced to quantify, for a fixed foundation layout and given soil sounding locations, the variability level of the foundation system bearing capacities in terms of their mean values and standard deviations. To estimate these measures, the recently proposed random failure mechanism method (RFMM) has been adopted and extended to consider any arrangement of rectangular foundations and boreholes. Hence, three-dimensional bearing capacity estimation under spatially variable soil can be efficiently performed. Several numerical examples are presented to illustrate the applicability of the proposed framework, including diverse foundation arrangements and different soil correlation structures. Overall, the proposed framework represents a potentially useful tool to support the design of geotechnical site investigation programs, especially in situations where very limited prior knowledge about the soil properties is available.

关键词： Foundations Geotechnical engineering Bearing capacity Optimal borehole placement Soil spatial variability