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Passive activity enhances residual control ability in patients with complete spinal cord injury

Neural Regeneration Research 2025年第8期20卷 2337-2347页

作者： Yanqing Xiao Mingming Gao Zejia He Jia Zheng Hongming Bai Jia-Sheng Rao Guiyun Song Wei Song Xiaoguang Li Beijing Key Laboratory for Biomaterials and Neural Regeneration Beijing Advanced Innovation Center for Biomedical EngineeringSchool of Biological Science and Medical EngineeringBeihang UniversityBeijingChina department of Rehabilitation Evaluation China Rehabilitation Research CenterBeijingChina Cardiac Center Beijing Children’s HospitalCapital Medical UniversityBeijingChina The State Key Laboratory of Virtual Reality Technology and Systems Beihang UniversityBeijingChina department of Rehabilitation engineering China Rehabilitation Science InstituteBeijingChina

Patients with complete spinal cord injury retain the potential for volitional muscle activity in muscles located below the spinal injury ***,because of prolonged inactivity,initial attempts to activate these muscles may not effectively engage any of the remaining neurons in the descending pathway.A previous study unexpectedly found that a brief clinical round of passive activity significantly increased volitional muscle activation,as measured by surface *** this study,we further explored the effect of passive activity on surface electromyographic signals during volitional control tasks among individuals with complete spinal cord *** patients with chronic complete thoracic spinal cord injury were *** electromyography data from eight major leg muscles were acquired and compared before and after the passive activity *** results indicated that the passive activity led to an increased number of activated volitional muscles and an increased frequency of *** the cumulative root mean square of surface electromyography amplitude for volitional control of movement showed a slight increase after passive activity,the difference was not statistically *** findings suggest that brief passive activity may enhance the ability to initiate volitional muscle activity during surface electromyography tasks and underscore the potential of passive activity for improving residual motor control among patients with motor complete spinal cord injury.

关键词： complete spinal cord injury cycle training epidural electrical stimulation motor training passive activity physiological state spinal cord circuit surface electromyography volitional control task

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A SCREW DISLOCATION BY NONLINEAR CONTINUUM mechanics

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Applied Mathematics and mechanics(English Edition) 1994年第12期15卷 1093-1102页

作者：潘客麟陈至达 1. department of engineering {2. Tongji University Shanghai 2. Peking Graduate School China University of Mining Beijing

Based on the nonlinear geometry field theory of continuum mechanics. this paper analyses the stress field due to a serew dislocation in an infinite an infinite medium . The results reveal the high-order effect of the stress field. When this effect is small. the result can be reduced to one of the classical linear elasticity. The body couple field of the serew dislocation is also investigated in this paper. The analytiecal expression of the body couple due to a serew dislocation is obtained with small rotation deformation. As the application of theoretical results. the stress and the body couple at the interface of the crystals are calculated when the serew dislocation is near the interface .

关键词： nonlinear geometric field. serew dislocation. body couple

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Multilevel analysis of the central-peripheral-target organ pathway:contributing to recovery after peripheral nerve injury

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Neural Regeneration Research 2025年第10期20卷 2807-2822页

作者： Xizi Song Ruixin Li Xiaolei Chu Qi Li Ruihua Li Qingwen Li Kai-Yu Tong Xiaosong Gu Dong Ming Academy of Medical engineering and Translational Medicine Tianjin UniversityTianjinChina Haihe Laboratory of Brain-Machine Interface and Human-Machine Fusion TianjinChina department of Rehabilitation Tianjin University Tianjin HospitalTianjinChina department of Hand Microsurgery Tianjin University Tianjin HospitalTianjinChina School of Exercise and Health Tianjin University of SportTianjinChina department of Biomedical engineering the Chinese University of Hong KongHong Kong Special Administrative RegionChina

Peripheral nerve injury is a common neurological condition that often leads to severe functional limitations and *** on the pathogenesis of peripheral nerve injury has focused on pathological changes at individual injury sites,neglecting multilevel pathological analysis of the overall nervous system and target *** has led to restrictions on current therapeutic *** this paper,we first summarize the potential mechanisms of peripheral nerve injury from a holistic perspective,covering the central nervous system,peripheral nervous system,and target *** peripheral nerve injury,the cortical plasticity of the brain is altered due to damage to and regeneration of peripheral nerves;changes such as neuronal apoptosis and axonal demyelination occur in the spinal *** nerve will undergo axonal regeneration,activation of Schwann cells,inflammatory response,and vascular system regeneration at the injury *** damage to target organs can occur,including skeletal muscle atrophy and sensory receptor *** then provide a brief review of the research advances in therapeutic approaches to peripheral nerve *** main current treatments are conducted passively and include physical factor rehabilitation,pharmacological treatments,cell-based therapies,and physical ***,most treatments only partially address the problem and cannot complete the systematic recovery of the entire central nervous system-peripheral nervous system-target organ ***,we should further explore multilevel treatment options that produce effective,long-lasting results,perhaps requiring a combination of passive(traditional)and active(novel)treatment methods to stimulate rehabilitation at the central-peripheral-target organ levels to achieve better functional recovery.

关键词： central nervous system central peripheral target organ multilevel pathological analysis nerve regeneration peripheral nerve injury peripheral nervous system target organs therapeutic approach

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Some key technics of drop tower experiment device of National Microgravity Laboratory (China) (NMLC)

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Science China(Technological Sciences) 2005年第3期48卷 305-316页

作者： ZHANG Xiaoqian 1 , YUAN Longgen 1 , WU Wendong 1 , TIAN Lanqiao 2.& YAO Kangzhuang 2.1. Institute of engineering Thermophysics, Chinese Academy of Sciences, Beijing 100080, China 2. Institute of mechanics, Chinese Academy of Sciences, Beijing 100080, China 1. Institute of engineering Thermophysics Chinese Academy of Sciences 100080 Beijing China 2. Institute of mechanics Chinese Academy of Sciences 100080 Beijing China

Drop tower is an important ground based facility for microgravity science experiment. The technical performances of the drop tower NMLC are advanced compared with similar facilities in the US, Germany and Japan. The main components such as drop capsule, deceleration devices, release mechanism present its advantages and creativities.

关键词： drop tower facility,drop capsule,deceleration devices,release mechanism.

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Gradient‑Layered MXene/Hollow Lignin Nanospheres Architecture Design for Flexible and Stretchable Supercapacitors

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Nano-Micro Letters 2025年第2期17卷 447-462页

作者： Haonan Zhang Cheng Hao Tongtong Fu Dian Yu Jane Howe Kaiwen Chen Ning Yan Hao Ren Huamin Zhai Jiangsu Provincial Key Lab of Sustainable Pulp and Paper Technology and Biomass Materials NanJing Forestry UniversityNanjing 210037People’s Republic of China department of Chemical engineering and Applied Chemistry University of Toronto200 College StreetTorontoON M5S 3E5Canada department of Materials Science and engineering University of Toronto184 College StreetTorontoON M5S 3E4Canada College of Materials Science and engineering Nanjing Forestry UniversityNanjing 210037People’s Republic of China

With the rapid development of flexible wearable electronics,the demand for stretchable energy storage devices has *** this work,a novel gradient-layered architecture was design based on single-pore hollow lignin nanospheres(HLNPs)-intercalated two-dimensional transition metal carbide(Ti_(3)C_(2.T_(x) MXene)for fabricating highly stretchable and durable *** depositing and inserting HLNPs in the MXene layers with a bottom-up decreasing gradient,a multilayered porous MXene structure with smooth ion channels was constructed by reducing the overstacking of MXene ***,the micro-chamber architecture of thin-walled lignin nanospheres effectively extended the contact area between lignin and MXene to improve ion and electron accessibility,thus better utilizing the pseudocapacitive property of *** these strategies effectively enhanced the capacitive performance of the *** addition,HLNPs,which acted as a protective phase for MXene layer,enhanced mechanical properties of the wrinkled stretchable electrodes by releasing stress through slip and deformation during the stretch-release cycling and greatly improved the structural integrity and capacitive stability of the *** electrodes and symmetric flexible all-solid-state supercapacitors capable of enduring 600%uniaxial tensile strain were developed with high specific capacitances of 12.3 mF cm^(−2.(2.1 F g^(−1))and 514 mF cm^(−2.(95 F g^(−1)),***,their capacitances were well preserved after 1000 times of 600%stretch-release *** study showcased new possibilities of incorporating biobased lignin nanospheres in energy storage devices to fabricate stretchable devices leveraging synergies among various two-dimensional nanomaterials.

关键词： Hollow lignin nanospheres MXene Gradient-layered architecture Wrinkled electrodes Stretchable supercapacitors

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NEW NUMERICAL METHOD FOR VOLTERRA INTEGRAL EQUATION OF THE SECOND KIND IN PIEZOELASTIC DYNAMIC PROBLEMS

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Applied Mathematics and mechanics(English Edition) 2004年第1期25卷 16-23页

作者：丁皓江王惠明陈伟球 department of Civil engineering department of mechanics

The elastodynamic problems of piezoelectric hollow cylinders and spheres under radial deformation can be transformed into a second kind Volterra integral equation about a function with respect to time, which greatly simplifies the solving procedure for such elastodynamic problems. Meanwhile, it becomes very important to find a way to solve the second kind Volterra integral equation effectively and quickly. By using an interpolation function to approximate the unknown function, two new recursive formulae were derived, based on which numerical solution can be obtained step by step. The present method can provide accurate numerical results efficiently. It is also very stable for long time calculating.

关键词： piezoelectric elastodynamic problem Volterra integral equation numerical solution recursive formulae

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A Bayesian expectation maximization algorithm for state estimation of intelligent vehicles considering data loss and noise uncertainty

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Science China Technological Sciences 2025年

作者： Yan WANG Feng TIAN Jianqiang WANG Keqiang LI department of Industrial and Systems engineering The Hong Kong Polytechnic University School of Vehicle and Mobility Tsinghua University

Sideslip angle, yaw rate, and vehicle velocity are essential for intelligent vehicle control. Since these vehicle states are not measured directly, some Kalman-based approaches have been developed to estimate these states using in-vehicle sensors. However, the existing studies seldom account for the influence of sensor data loss on estimation accuracy. In addition,the process and measurement noise change during the estimation process because of the various driving conditions. To address these problems, an expectation-maximization robust extended Kalman filter (EMREKF) is proposed. Firstly, a robust extended Kalman filter (REKF) is developed to deal with the impact of missing measurements. Then, an improved expectation maximization (EM) algorithm that considers data loss is presented to update the noise parameter of the REKF dynamically. Finally,the improved EM is fused with the REKF to form the EMREKF to estimate vehicle state. The experimental results demonstrate that the EMREKF outperforms EKF, REKF, and maximum correntropy criterion EKF for various degrees of data loss and the proposed algorithm has a strong adaptive ability to different driving conditions.

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Multi-scale fatigue damage model for steel structures working under high temperature

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Acta Mechanica Sinica 2019年第3期35卷 615-623页

作者： Huajing Guo Bin Sun Zhaoxia Li department of engineering {2. Jiangsu Key Laboratory of Engineering MechanicsSoutheast UniversityNanjing 210096China

In order to better understand the fatigue mechanisms of steel structures working under high temperature, a multi-scale fatigue damage model at high temperature is developed. In the developed model, the macroscopic fatigue damage of metallic materials due to the collective behavior of micro-cracks is quantified by using the generalized self-consistent method. The influence of temperature on fatigue damage of steel structures is quantified by using the previous creep damage model. In addition, the fatigue damage at room temperature and creep damage is coupled in the multi-scale fatigue damage model. The validity of the developed multi-scale damage model is verified by comparing the predicted damage evolution curve with the experimental data. It shows that the developed model is effectiveness. Finally, the fatigue analysis on steel crane runway girders (CRGs) of industrial steel melt shop is performed based on the developed model.

关键词： Steel structures High temperature Multi-scale damage model Microcracks Generalized self-consistentmethod

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A fractional differential constitutive model for dynamic stress intensity factors of an anti-plane crack in viscoelastic materials

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Acta Mechanica Sinica 2014年第3期30卷 403-409页

作者： Run-Tao Zhan Zhao-Xia Li Lei Wang department of engineering {2. Southeast UniversityJiangsu Key Laboratory of Engineering Mechanics School of Civil engineering Southeast University

Fractional differential constitutive relationships are introduced to depict the history of dynamic stress inten- sity factors （DSIFs） for a semi-infinite crack in infinite viscoelastic material subjected to anti-plane shear impact load. The basic equations which govern the anti-plane deformation behavior are converted to a fractional wave-like equation. By utilizing Laplace and Fourier integral transforms, the fractional wave-like equation is cast into an ordinary differential equation （ODE）. The unknown function in the solution of ODE is obtained by applying Fourier transform directly to the boundary conditions of fractional wave-like equation in Laplace domain instead of solving dual integral equations. Analytical solutions of DSIFs in Laplace domain are derived by Wiener-Hopf technique and the numerical solutions of DSIFs in time domain are obtained by Talbot algorithm. The effects of four parameters α, β, b1, b2.of the fractional dif- ferential constitutive model on DSIFs are discussed. The numerical results show that the present fractional differential constitutive model can well describe the behavior of DSIFs of anti-plane fracture in viscoelastic materials, and the model is also compatible with solutions of DSIFs of anti-plane fracture in elastic materials.

关键词： Dynamic fracture Stress intensity factors Fractional differentiation - Anti-plane fracture Viscoelasticmaterial Wiener-Hopf

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Critical transition Reynolds number for plane channel flow

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Applied Mathematics and mechanics(English Edition) 2017年第10期38卷 1415-1424页

作者： Yongming ZHANG department of mechanics Tianjin University Tianjin Key Laboratory of Modern engineering mechanics

The determination of the critical transition Reynolds number is of practical importance for some engineering problems. However, it is not available with the current theoretical method, and has to rely on experiments. For supersonic/hypersonic boundary layer flows, the experimental method for determination is not feasible either. Therefore, in this paper, a numerical method for the determination of the critical transition Reynolds number for an incompressible plane channel flow is proposed. It is basically aimed to test the feasibility of the method. The proposed method is extended to determine the critical Reynolds number of the supersonic/hypersonic boundary layer flow in the subsequent papers.

关键词： critical transition Reynolds number plane channel flow boundary layerflow

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