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犬隐孢子虫病的诊治

中国工作犬业 2024年第6期 50-51页

作者：葛学忠张思维哈尔滨铁路公安局警犬繁育训练支队(基地) 150056

隐孢子虫是一种细胞内寄生并能引起人和动物腹泻、全球普遍存在的人畜共患寄生虫。隐孢子虫属有效虫种多达41种,其中人隐孢子虫、火鸡隐孢子虫、犬隐孢子虫和猫隐孢子虫是人体隐孢子虫感染病例的常见虫体,它们都对人类健康具有潜在威胁... 详细信息

隐孢子虫是一种细胞内寄生并能引起人和动物腹泻、全球普遍存在的人畜共患寄生虫。隐孢子虫属有效虫种多达41种,其中人隐孢子虫、火鸡隐孢子虫、犬隐孢子虫和猫隐孢子虫是人体隐孢子虫感染病例的常见虫体,它们都对人类健康具有潜在威胁。犬隐孢子虫是寄生于犬科动物的主要虫种,一般认为是肠道寄生虫,寄生在小肠上皮细胞的刷状缘纳虫空泡内,也有报道称可寄生于胃部上皮细胞,造成消化吸收功能障碍,引起犬腹泻。

关键词：人畜共患寄生虫隐孢子虫肠道寄生虫小肠上皮细胞动物腹泻犬科动物寄生虫体

Role of Oncostatin M in the prognosis of inflammatory bowel disease: A meta-analysis

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World Journal of Gastrointestinal Surgery 2024年第1期16卷 228-238页

作者： Yue Yang Kan-Zuo Fu Gu Pan Department of Gastroenterology III Heilongjiang Provincial HospitalHarbin 150036Heilongjiang ProvinceChina Department of Nursing The Second Hospital of HarbinHarbin 150056Heilongjiang ProvinceChina

BACKGROUND Oncostatin M(OSM)is a pleiotropic cytokine which is implicated in the path-ogenesis of inflammatory bowel disease(IBD).AIM To evaluate the prognostic role of OSM in IBD *** Literature search was conducted in electronic databases(Google Scholar,Embase,PubMed,Science Direct,Springer,and Wiley).Studies were selected if they reported prognostic information about OSM in IBD *** data were synthesized,and meta-analyses were performed to estimate standardized mean differences(SMDs)in OSM levels between treatment responders and non-res-ponders and to seek overall correlations of OSM with other inflammatory *** Sixteen studies(818 Crohn’s disease and 686 ulcerative colitis patients treated with anti-tumor necrosis factor-based therapies)were *** levels were associated with IBD severity.A meta-analysis found significantly higher OSM levels in non-responders than in responders to therapy[SMD 0.80(0.33,1.27);P=0.001],in non-remitters than in remitters[SMD 0.75(95%CI:0.35 to 1.16);P<0.0001]and in patients with no mucosal healing than in those with mucosal heal-ing[SMD 0.63(0.30,0.95);P<0.0001].Area under receiver operator curve values showed considerable variability between studies but in general higher OSM levels were associated with poor *** had significant correlations with Simple Endoscopic Score of Crohn’s disease[r=0.47(95%CI:0.25 to 0.64);P<0.0001],Mayo Endoscopic Score[r=0.35(95%CI:0.28 to 0.41);P<0.0001],fecal calprotectin[r=0.19(95%CI:0.08 to 0.3);P=0.001],C-reactive protein[r=0.25(95%CI:0.11 to 0.39);P<0.0001],and platelet count[r=0.28(95%CI:0.17 to 0.39);P<0.0001].CONCLUSION OSM is a potential candidate for determining the severity of disease and predicting the outcomes of anti-tumor necrosis factor-based therapies in IBD patients.

关键词： Inflammatory bowel disease Crohn’s disease Ulcerative colitis Oncostatin M Prognosis

单采血小板捐献者捐献频次对血红蛋白和血清铁蛋白变化的影响

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哈尔滨医药 2024年第1期44卷 60-62页

作者：李继红孙晨虞菲崔志刚刘颖黑龙江省血液中心黑龙江哈尔滨150056

目的探讨单采血小板捐献者捐献频次对其体内血红蛋白(Hb)及血清铁蛋白(SF)变化的影响。方法随机选取469例单采血小板捐献者的血液样本,分析单采血小板捐献者1年内捐献频次对血红蛋白(Hb)及血清铁蛋白(SF)的影响,从而探讨单采血小板不同... 详细信息

目的探讨单采血小板捐献者捐献频次对其体内血红蛋白(Hb)及血清铁蛋白(SF)变化的影响。方法随机选取469例单采血小板捐献者的血液样本,分析单采血小板捐献者1年内捐献频次对血红蛋白(Hb)及血清铁蛋白(SF)的影响,从而探讨单采血小板不同频次的捐献者体内储铁情况,以判断是否需要补充铁剂制品。结果1年内单采小板捐献者献血频次与SF成负相关,随着献血频次的增加,SF水平不断下降,差异有统计学意义(P0.05)。结论对1年内单采血小板次数>16次的男性捐献者和1年内单采血小板次数>10次的女性捐献者应减少再次招募的频次,如有必要可以增加单采血小板前SF的检测,若发现铁缺乏,则延长献血间隔期,适量增加铁剂制品的补充。

关键词：单采血小板固定捐献者献血频次血红蛋白血清铁蛋白

家庭参与式护理干预对精神分裂症患者生活质量的影响

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中文科技期刊数据库（文摘版）医药卫生 2024年第9期 0075-0078页

作者：杨可欣周鑫鑫崔永兰哈尔滨市第一专科医院黑龙江哈尔滨150056

分析家庭参与式护理干预对精神分裂症患者生活质量的影响。方法选取60例精神分裂症患者,分为参照组(30例,实施常规护理),观察组(30例,实施家庭护理)。结果观察组护理6个月的依从性评分高于参照组,SDSS评分低于参照组;观察组的不良情... 详细信息

分析家庭参与式护理干预对精神分裂症患者生活质量的影响。方法选取60例精神分裂症患者,分为参照组(30例,实施常规护理),观察组(30例,实施家庭护理)。结果观察组护理6个月的依从性评分高于参照组,SDSS评分低于参照组;观察组的不良情况发生率低于参照组;观察组的护理满意度高于参照组。结论家庭护理不仅能维持好患者出院后的依从性,还能使患者的病情相对稳定,较少出现不良情况,治疗效果和预后较理想,有助于提高护理满意度。

关键词：家庭护理精神分裂症服药依从性

The link between dietary nutrients intake and cardiovascular diseases in cold regions

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Frigid Zone Medicine 2024年第1期4卷 1-11页

作者： Rennan Feng Qianqi Hong Jingjing Cao Jian Li Lanxin Deng Jing Wang Yang Zhao Cheng Wang Department of Nutrition and Food Hygiene Public Health CollegeHarbin Medical UniversityHarbin150081China Department of Environmental Hygiene School of Public HealthHarbin Medical UniversityHarbin 150081China Harbin Center for Disease Control and Prevention Harbin 150056China

Background:The cold winter weather in northern China influences the dietary habits of its residents,contributing to a heightened risk of cardiovascular disorders,such as hypertension and coronary heart *** factors include low vegetable consumption and high salt and fat *** study aims to investigate the relationships between northern dietary nutrient intake in northern China and cardiovascular disorders during the winter ***:A food frequency questionnaire tailored to the actual eating habits in northern China was *** data from 955 Chinese adults were collected from November to March between 2014 to *** regression was employed to analyze the relationship between dietary nutrients and cardiovascular diseases,with model performance assessed using receiver operating characteristic(ROC)***:Adjusted for gender,age,and body mass index(BMI),an inverse association was observed between vitamin A(OR=0.706,95%CI:0.550,0.907),nicotinic acid(OR=0.584,95%CI:0.447,0.762),phosphorus(OR=0.777,95%CI:0.608,0.994),selenium(OR=0.719,95%CI:0.560,0.923),zinc(OR=0.683,95%CI:0.531,0.880),methionine(OR=0.730,95%CI:0.569,0.936),arginine(OR=0.753,95%CI:0.588,0.964),lysine(OR=0.706,95%CI:0.550,0.907),aspartic acid(OR=0.730,95%CI:0.569,0.936)and ***,a negative association was found between niacin(OR=0.752,95%CI:0.597,0.946)and coronary heart ***,a positive association was identified between iodine and hypertension(OR=1.305,95%CI:1.020,1.669)and coronary heart disease(OR=1.301,95%CI:1.037,1.634).Conclusion:Our study suggests that maintaining a balanced dietary intake of vitamin A,niacin,phosphorus,selenium,zinc,methionine,arginine,lysine,and aspartic acid can be beneficial in preventing *** niacin intake is associated with a lower risk of coronary heart ***,excessive iodine intake may contribute to hypertension and coronary heart disease.

关键词： nutrients northern hypertension coronary heart disease cold

2022年哈尔滨市精神卫生医疗机构现状调查

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中国卫生标准管理 2024年第1期15卷 57-60页

作者：李玺琨张于刘丽萍哈尔滨市第一专科医院精神心理科黑龙江哈尔滨150056

目的探讨哈尔滨市域内一级以上注册有精神科的民营及公立医疗机构基本情况和运营现状。方法自拟《哈尔滨市精神专科医院基本情况调查表》面向2022年1—12月在哈尔滨市开设精神科的56家医疗机构收集精神卫生服务资源相关数据,对机构、床... 详细信息

目的探讨哈尔滨市域内一级以上注册有精神科的民营及公立医疗机构基本情况和运营现状。方法自拟《哈尔滨市精神专科医院基本情况调查表》面向2022年1—12月在哈尔滨市开设精神科的56家医疗机构收集精神卫生服务资源相关数据,对机构、床位、人员数量等进行描述性分析。结果哈尔滨市目前开展业务的精神卫生医疗机构22家,共有床位数7107张。精神卫生工作人员3701名,其中精神科医师505名(占13.64%)。门诊年服务人次数共308178人次,急诊服务人次数共547人次,年入院共计37057人次。哈尔滨市每个精神科医师平均年负担门诊610人次,年负担住院73人次。结论哈尔滨市精神卫生机构配置不足,精神科医师工作量较大,投入不足,难以满足逐渐增长的精神卫生服务需求。

关键词：哈尔滨精神卫生医疗机构资源配置现状调查运营

Deep learning model based on PET/CT and combination with Cox proportional hazard model for predicting progression of lung invasive adenocarcinoma after surgery

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中国医学影像技术 2024年第8期40卷 1194-1198页

作者： LI Yingci WU Dongbo GONG Feifei Department of PET/CT-MR Center Harbin Medical University Cancer HospitalHarbin 150081China Department of Radiology Harbin Medical University Cancer HospitalHarbin 150081China Department of Radiology Harbin Chest HospitalHarbin 150056China

Objective To observe the efficacy of deep learning(DL)model based on PET/CT and its combination with Cox proportional hazard model for predicting progressive disease(PD)of lung invasive adenocarcinoma within 5 years after *** The clinical,PET/CT and 5-year follow-up data of 250 patients with lung invasive adenocarcinoma were retrospectively *** to PD or not,the patients were divided into the PD group(n=71)and non-PD group(n=179).The basic data and PET/CT findings were compared between groups,among which the quantitative variables being significant different between groups were transformed to categorical variables using receiver operating characteristic(ROC)curve and corresponding cut-off *** Cox proportional hazard model was used to select independent predicting factors of PD of lung invasive adenocarcinoma within 5 years after *** patients were divided into training,validation and test sets at the ratio of 6∶2∶2,and PET/CT data in training set and validation set were used to train model and tuning parameters to build the PET/CT DL model,and the combination model was built in serial connection of DL model and the predictive *** test set,the efficacy of each model for predicting PD of lung invasive adenocarcinoma within 5 years after surgery was assessed and compared using the area under the curve(AUC).Results Patients'gender and smoking status,as well as the long diameter,SUV max and SUV mean of lesions measured on PET images,the long diameter,short diameter and type of lesions showed on CT were statistically different between groups(all P4.15(HR=5.249[1.062,25.945],P=0.042)were both predictors of PD of lung invasive adenocarcinoma within 5 years after *** test set,the AUC of PET/CT DL model for predicting PD was 0.847,of the combination model was 0.890,of the latter was higher than of the former(P=0.036).Conclusion DL model based on PET/CT

关键词： adenocarcinoma of lung positron-emission tomography and computed tomography deep learning disease progression

全自动尿碘仪在尿碘、水碘和盐碘质控考核的应用分析

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中国地方病防治 2024年第1期39卷 40-42页

作者：李百慧曹建滨赵鸿鹏张文翠闫飞于天龙哈尔滨市疾病预防控制中心黑龙江150056

目的获得一种快捷高效、准确灵敏的测定尿碘、水碘、盐碘检测方法。方法通过全自动碘分析仪法对尿碘、水碘、盐碘质控样和考核样进行检测,分析全自动碘分析仪法标准系列的线性范围、检出限、加标回收率、准确度、精密度,并对仪器法与手... 详细信息

目的获得一种快捷高效、准确灵敏的测定尿碘、水碘、盐碘检测方法。方法通过全自动碘分析仪法对尿碘、水碘、盐碘质控样和考核样进行检测,分析全自动碘分析仪法标准系列的线性范围、检出限、加标回收率、准确度、精密度,并对仪器法与手工法检测结果进行t检验比较。结果尿碘方法在0~~300μg/L标准曲线范围内吸光度的对数与浓度成线性,相关系数r=-0.9999,检出限为3.5μg/L,2个浓度尿碘标准物质的测定值均在规定的不确定度范围内,平均加标回收率在91.2%~99.2%之间,相对标准偏差(RSD)为0.21%~1.62%(n=6)。水碘方法在含碘量0~100μg/L标准曲线范围内吸光度的对数与浓度呈线性,相关系数r=-0.9999,检出限为1.2μg/L,2个浓度水碘标准物质的测定值均在规定的不确定度范围内,平均加标回收率在92.7%~100.4%之间,RSD为0.35%~2.59%(n=6)。盐碘方法在含碘量0~3.0mg/L标准曲线范围内吸光度的对数与浓度呈线性,相关系数r=0.9998,检出限为0.26mg/kg,2个浓度盐碘标准物质的测定值均在规定的不确定度范围内,平均加标回收率在98.5%~102.1%之间,RSD为0.76%~1.02%(n=6)。全自动尿碘仪测定尿、水、盐盲样的结果与传统手工方法测定值经t检验比较,差异无统计学意义(P>0.05)。结论该方法代替传统的手工法,操作方便快捷,灵敏度、准确度、精密度均符合检测要求。

关键词：尿碘水碘盐碘检测

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课程思政融入中职计算机专业课教学探讨

成才之路 2024年第10期 81-84页

作者：曲云波黑龙江省哈尔滨市商业学校黑龙江哈尔滨150056

课程思政是一种重要的思想政治教育方法,具有深远的意义和作用。中职学生正处于世界观、人生观、价值观形成的关键时期,他们需要通过各类课程的学习来认识社会、了解职业、规划未来。将思政教育融入计算机专业课教学可以提升学生的思想... 详细信息

课程思政是一种重要的思想政治教育方法,具有深远的意义和作用。中职学生正处于世界观、人生观、价值观形成的关键时期,他们需要通过各类课程的学习来认识社会、了解职业、规划未来。将思政教育融入计算机专业课教学可以提升学生的思想道德品质和综合素质,增强学生的专业能力,为未来社会培养合格的服务与建设人才。文章阐述课程思政的基本内涵,强调课程思政融入中职计算机专业课教学的意义,提出课程思政融入中职计算机专业课教学存在的问题,探讨课程思政融入中职计算机专业课教学的策略,旨在为今后的课程思政教学提供参考与借鉴。

关键词：中职学校计算机专业课程思政人才培养问题策略