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Mechanical responses and crystal plasticity model of CoCrNi medium-entropy alloy under ramp wave compression

Matter and Radiation at Extremes 2024年第5期9卷 93-108页

作者： Jinlei Dong Xuping Zhang Guiji Wang Xianqian Wu Binqiang Luo Xuemiao Chen Fuli Tan Jianheng Zhao Chengwei Sun institute of Fluid Physics China Academy of Engineering PhysicsMianyang 621999China institute of Mechanics Chinese Academy of SciencesBeijing 100190China institute of {1. electronics China Academy of Engineering PhysicsMianyang 621999China

It is of substantial scientific significance and practical value to reveal and understand the multiscale mechanical properties and intrinsic mechanisms of medium-entropy alloys(MEAs)under high strain rates and *** this study,the mechanical responses and deformation mechanisms of an equiatomic CoCrNi MEA are investigated utilizing magnetically driven ramp wave compression(RWC)with a strain rate of 1.5 s^(−1..The CoCrNi MEA demonstrates excellent dynamic mechanical responses and yield strength under RWC compared with other advanced *** characterizations reveal that grain refinement and abundant micromechanisms,including dislocation slip,stacking faults,nanotwin network,and Lomer–Cottrell locks,collectively contribute to its excellent performance during ***,dense deformation twins and shear bands intersect,forming a weave-like microstructure that can disperse deformation and enhance *** the basis of these observations,we develop a modified crystal plasticity model with coupled dislocation and twinning mechanisms,providing a relatively accurate quantitative description of the multiscale behavior under *** results of simulations indicate that the activation of multilevel microstructures in CoCrNi MEA is primarily attributable to stress inhomogeneities and localized strain during *** research offers valuable insights into the dynamic mechanical responses of CoCrNi MEA,positioning it as a promising material for use under extreme dynamic conditions.

关键词： deformation alloy microstructure

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Exploration of microscopic physical processes of Z-pinch by a modified electrostatic direct implicit particle-in-cell algorithm

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Chinese Physics B 2024年第9期33卷 433-442页

作者： Kaixuan Li Cheng Ning Ye Dong Chuang Xue institute of {1. Physics and Computational Mathematics Beijing 100088China

For investigating efficiently the stagnation kinetic-process of Z-pinch,we develop a novel modified electrostatic implicit particle-in-cell algorithm in radial one-dimension for Z-pinch simulation in which a small-angle cumulative binary collision algorithm is *** our algorithm,the electric field in z-direction is solved by a parallel electrode-plate model,the azimuthal magnetic field is obtained by Ampere’s law,and the term for charged particle gyromotion is approximated by the cross product of the averaged velocity and magnetic *** simulation results of 2 MA deuterium plasma shell Zpinch,the mass-center implosion trajectory agrees generally with that obtained by one-dimensional MHD simulation,and the plasma current also closely aligns with the external *** phase space diagrams and radial-velocity probability distributions of ions and electrons are *** main kinetic characteristic of electron motion is thermal equilibrium and oscillation,which should be oscillated around the ions,while that of ion motion is implosion *** the region of stagnation radius,the radial-velocity probability distribution of ions transits from the non-equilibrium to equilibrium state with the current increasing,while of electrons is basically the equilibrium *** the initial ion density and current peak are not high enough,the ions may not reach their thermal equilibrium state through collisions even in its stagnation phase.

关键词： Z-pinch particle-in-cell ion heating charged particle collisions

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Real-time monitoring of oxygenation in deep brain tissue using a wireless photoelectric probe

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Science China Materials 2024年第4期67卷 1361-1362页

作者： Hao Pang Qilin Hua Guozhen Shen School of Integrated Circuits and electronics Beijing Institute of TechnologyBeijing 100084China institute of Flexible {1. Beijing Institute of TechnologyBeijing 102488China

Oxygen(O2) supply to the brain is of utmost importance for human health, as cerebral hypoxia can result in irreversible brain damage. Neurodegenerative diseases, such as epilepsy, are closely associated with cerebral hypoxia [1.2]. Real-time monitoring of cerebral oxygenation holds significant value in neuroscience research and clinical diagnostics [3–1.].

关键词： epilepsy cerebral diseases

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Tianmouc vision chip designed for open-world sensing

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Science China Materials 2024年第9期67卷 3046-3048页

作者： Haotian Li Qilin Hua Guozhen Shen School of Integrated Circuits and electronics Beijing Institute of TechnologyBeijing100081China institute of Flexible {1. Beijing Institute of TechnologyBeijing102488China

Driven by the forward development of highly interactive applications like autonomous robots and artificial intelligence[1.2],image sensors are continuously demanded to improve in terms of high speed,high resolution,wide dynamic range,and high precision[3].However,due to inherent limitations in power and bandwidth,significant enhancements in one aspect often necessitates compromises in others[4].

关键词： artificial interactive autonomous

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Wireless multisite sensing systems for continuous physiological monitoring

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Science China Materials 2024年第6期67卷 2045-2047页

作者： Ruilai Wei Qilin Hua Guozhen Shen School of Integrated Circuits and electronics Beijing Institute of TechnologyBeijing 100081China institute of Flexible {1. Beijing Institute of TechnologyBeijing 102488China

Respiratory diseases rank as the third leading cause of adult mortality[1.,while cardiopulmonary and gastrointestinal issues are the primary cause of death within the first five years of a child’s life[2].The monitoring of cardiac,respiratory,and gastrointestinal sounds plays a vital role in routine care,as alterations or absence of these body sounds can serve as indicators of underlying diseases.

关键词： routine continuous monitoring

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Explaining the dynamics of the sub-relativistic electron third belt in the Earth's radiation belts by using medium Earth orbit satellite observations

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Earth and Planetary Physics 2024年第5期8卷 762-775页

作者： JiaLi Chen Hong Zou YuGuang Ye institute of Space Physics and {1. Technology Peking University

The Earth's electron radiation belts typically exhibit a two-belt structure. However, observations from the Van Allen Probes revealed the existence of a three-belt structure. This structure consists of an inner belt, a slot region, a remnant belt, a “second slot,” and a new outer belt(or the “third belt”). The formation of the structure involves both the partial loss of the original outer belts and the formation of the third belts. These processes are likely associated with radial diffusion induced by ultra-low-frequency(ULF) waves. In this study, we mainly analyzed electron flux data from medium Earth orbit(MEO) navigation satellites M1.–M1. to supplement the observational evidence for the sub-relativistic electron(～1.0–500 keV) three-belt structure. Evidence of substorm injections and ULF waves during the three-belt event was identified, suggesting they played significant roles in the formation and evolution of the third *** injections may introduce new electron populations to the third belt, whereas ULF waves may influence the evolution of the third belt through radial diffusion. Toward the end of the three-belt event, the compression of the magnetosphere by shocks may lead to the dropout of the third belt because of the magnetopause shadowing effect and outward radial diffusion, ultimately disrupting the three-belt structure. This study provides more evidence for the presence of a sub-relativistic electron three-belt structure and offers an analysis of the evolutionary mechanisms of the third belt, which may contribute to a comprehensive understanding of the electron three-belt structure in the radiation belts.

关键词： third belt sub-relativistic electrons three-belt structure radiation belts magnetic storms and substorms wave–particle interactions

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Bioinspired 3D flexible devices and functional systems

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National Science Review 2024年第3期11卷 271-295页

作者： Xu Cheng Zhangming Shen Yihui Zhang applied Mechanics Laboratory Department of Engineering Mechanics Tsinghua University Laboratory of Flexible electronics Technology Tsinghua University

Flexible devices and functional systems with elaborated three-dimensional(3D) architectures can endow better mechanical/electrical performances, more design freedom, and unique functionalities, when compared to their two-dimensional(2D) counterparts. Such 3D flexible devices/systems are rapidly evolving in three primary directions, including the miniaturization, the increasingly merged physical/artificial intelligence and the enhanced adaptability and capabilities of heterogeneous *** challenges exist in this emerging research area, such as relatively poor controllability in the locomotion of soft robotic systems, mismatch of bioelectronic interfaces, and signal coupling in multi-parameter sensing. By virtue of long-time–optimized materials, structures and processes, natural organisms provide rich sources of inspiration to address these challenges, enabling the design and manufacture of many bioinspired 3D flexible devices/systems. In this Review, we focus on bioinspired 3D flexible devices and functional systems, and summarize their representative design concepts, manufacturing methods, principles of structure-function relationship and broad-ranging applications. Discussions on existing challenges, potential solutions and future opportunities are also provided to usher in further research efforts toward realizing bioinspired 3D flexible devices/systems with precisely programmed shapes,enhanced mechanical/electrical performances, and high-level physical/artificial intelligence.

关键词： bioinspired designs biomimetic 3D structures 3D flexible electronics 3D functional systems direct 3D manufacture 2D-to-3D assembly

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INCOMPRESSIBLE LIMIT OF IDEAL MAGNETOHYDRODYNAMICS IN A DOMAIN WITH BOUNDARIES

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Acta Mathematica Scientia 2024年第4期44卷 1441-1465页

作者： Qiangchang JU Jiawei WANG institute of {1. Physics and Computational Mathematics Beijing 100088China

We study the incompressible limit of classical solutions to compressible ideal magneto-hydrodynamics in a domain with a flat *** boundary condition is characteristic and the initial data is *** first establish the uniform existence of classical solutions with respect to the Mach ***,we prove that the solutions converge to the solution of the incompressible MHD *** particular,we obtain a stronger convergence result by using the dispersion of acoustic waves in the half space.

关键词： incompressible limit ideal MHD equations boundary condition general initial data

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Study of damage behavior and repair effectiveness of patch repaired carbon fiber laminate under quasi-static indentation loading

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Defence Technology（防务技术） 2024年第4期34卷 29-41页

作者： Alok Kumar Chinmaya Kumar Sahoo A.Arockiarajan Department of applied Mechanics Indian Institute of Technology MadrasChennai 600036India

Damage caused due to low-velocity impacts in composites leads to substantial deterioration in their residual strength and eventually provokes structural *** work presents an experimental investigation on the effects of different patch and parent laminate stacking sequences on the enhancement of impact strength of Carbon Fiber Reinforced Polymers(CFRP)composites by utilising the adhesively bonded external patch repair *** evolution study is also performed with the aid of Acoustic Emission(AE).Two different quasi-isotropic configurations were selected for the parent laminate,viz.,[45°/45°/0°/0°]s and[45°/0°/45°/0°]*** Static Indentation(QSI)test was performed on both the pristine laminates,and damage areas were detected by using the C-scan inspection *** laminates were repaired by using a single-sided patch of two different configurations,viz.,[45°/45°/45°/45°]and[45°/0°/0°/45°],and employing a circular plug to fill the damaged *** different combinations of repaired laminates with two configurations of each parent and patch laminate were produced,which were further subjected to the QSI *** results reveal the effectiveness of the repair method,as all the repaired laminates show higher impact resistance compared to the respective pristine *** of[45°/0°/0°/45°]configuration when repaired by taking[45°/45°/0°/0°]s and[45°/0°/45°/0°]s as parents exhibited 68%and 73%higher peak loads,respectively,than the respective pristine ***,parent and patch of configuration[45°/0°/45°/0°]s and[45°/0°/0°/45°],respectively,attain the highest peak load,whereas[45°/45°/0°/0°]s and[45°/45°/45°/45°]combinations possess the most gradual decrease in the load.

关键词： Carbon fiber reinforced polymers(CFRP) Quasi-isotropic laminate Quasi static indentation(QSI) Acoustic emission(AE) Composite repair

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Introducing urea into tirapazamine derivatives to enhance anticancer therapy

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National Science Review 2024年第4期11卷 245-253页

作者： Yajun Xu Jianlin Lv Chaoying Kong Ya Liu Kun Wang Zhaohui Tang Xuesi Chen Key Laboratory of Polymer Ecomaterials Changchun Institute of Applied ChemistryChinese Academy of Sciences School of applied Chemistry and Engineering University of Science and Technology of China

Tirapazamine（TPZ） has been approved for multiple clinical trials relying on its excellent anticancer ***,as a typical hypoxia-activated prodrug（HAP）,TPZ did not exhibit survival advantages in Phase Ⅲ clinical trials when used in combination therapy due to the insufficient hypoxia levels in patients' *** this study,to improve the therapeutic effects of TPZ,we first introduced urea to synthesize a series of urea-containing derivatives of *** urea-containing TPZ derivatives showed increased hypoxic cytotoxicity（9.51.30.85-fold） compared with TPZ,while maintaining hypoxic ***,one of these derivatives,showed 20-fold higher cytotoxicity than TPZ while maintaining a similar hypoxic cytotoxicity *** highly efficiently deliver TPZP to the tumors and reduce its side effects on healthy tissues,we further prepared TPZP into a nanodrug with fibrin-targeting ability:***4-NPs,a vascular disrupting agent,was used to increase the fibrin level within tumors and exacerbate tumor *** being combined with CA4-NPs,FT1.-TPZP-NPs can accumulate in the hypoxia-aggravated tumors and activate sufficiently to kill tumor *** a single-dose treatment,FT1.-TPZP-NPs+CA4-NPs showed a high inhibition rate of 98.1. against CT26 tumor models with an initial volume of ～480 mm3and four out of six tumors were completely eliminated;it thereby exerted a significant antitumor *** study provides a new strategy for improving the therapeutic effect of TPZ and other HAPs in anticancer therapy.

关键词： tirapazamine vascular disrupting agent hypoxia-activated prodrug combretastatin A4 urea

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