检索结果-南通市图书馆

World Journal of Clinical Cases 2024年第6期12卷 1174-1181页

作者： Yu-Jie Qin Ting Gao Xing-Nian Zhou Ming-Liang Cheng Hong Li Clinical Medicine School of guizhou Medical {1. Guiyang 550025Guizhou ProvinceChina Department of Pathology The Affiliated Hospital of Guizhou Medical UniversityGuiyang 550025Guizhou ProvinceChina Department of Infectious Diseases Guizhou Medical UniversityGuiyang 550025Guizhou ProvinceChina Department of Infectious Diseases Guizhou Provincial People's HospitalGuiyang 550025Guizhou ProvinceChina

BACKGROUND Autoimmune hepatitis(AIH)and primary biliary cholangitis(PBC)are two common clinical autoimmune liver diseases,and some patients have both diseases;this feature is called AIH-PBC overlap *** thyroid disease(AITD)is the most frequently overlapping extrahepatic autoimmune ***(IgG)4-related disease is an autoimmune disease recognized in recent years,characterized by elevated serum IgG4 levels and infiltration of IgG4-positive plasma cells in *** SUMMARY A 68-year-old female patient was admitted with a history of right upper quadrant pain,anorexia,and jaundice on physical *** examination revealed elevated liver enzymes,multiple positive autoantibodies associated with liver and thyroid disease,and imaging and biopsy suggestive of pancreatitis,hepatitis,and PBC.A diagnosis was made of a rare and complex overlap syndrome of AIH,PBC,AITD,and IgG4-related *** features improved on treatment with ursodeoxycholic acid,methylprednisolone,and *** This case highlights the importance of screening patients with autoimmune diseases for related conditions.

关键词： Overlap syndrome Autoimmune hepatitis Primary biliary cholangitis Primary sclerosing cholangitis Autoimmune thyroid disease Case report

Comparison of CWSI and T_(s)-T_(a)-VIs in moisture monitoring of dryland crops(sorghum and maize)based on UAV remote sensing

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2024年第7期23卷 2458-2475页

作者： Hui Chen Hongxing Chen Song Zhang Shengxi Chen Fulang Cen Quanzhi Zhao Xiaoyun Huang Tengbing He Zhenran Gao College of Agriculture Guizhou UniversityGuiyang 550025China Institute of New Rural Development Guizhou UniversityGuiyang 550025China Institute of Rice Industry Technology Research College of Agricultural SciencesGuizhou UniversityGuiyang 550025China

Monitoring agricultural drought using remote sensing data is crucial for precision irrigation in modern *** unmanned aerial vehicle(UAV)remote sensing,we explored the applicability of an empirical crop water stress index(CWSI)based on canopy temperature and three-dimensional drought indices(TDDI)constructed from surface temperature(T_(s)),air temperature(T_(a))and five vegetation indices(VIs)for monitoring the moisture status of dryland *** machine learning algorithms(random forest regression(RFR),support vector regression,and partial least squares regression)were used to compare the performance of the drought indices for vegetation moisture content(VMC)estimation in sorghum and *** main results of the study were as follows:(1.Comparative analysis of the drought indices revealed that T_(s)-T_(a)-normalized difference vegetation index(TDDIn)and T_(s)-T_(a)-enhanced vegetation index(TDDIe)were more strongly correlated with VMC compared with the other *** indices exhibited varying sensitivities to VMC under different irrigation regimes;the strongest correlation observed was for the TDDIe index with maize under the fully irrigated treatment(r=-0.93).(2)Regarding spatial and temporal characteristics,the TDDIn,TDDIe and CWSI indices showed minimal differences Over the experimental period,with coefficients of variation were 0.25,0.1. and 0.24,*** three indices were capable of effectively characterizing the moisture distribution in dryland maize and sorghum crops,but the TDDI indices more accurately monitored the spatial distribution of crop moisture after a rainfall or irrigation event.(3)For prediction of the moisture content of single crops,RFR models based on TDDIn and TDDIe estimated VMC most accurately(R^(2)>0.7),and the TDDIn-based model predicted VMC with the highest accuracy when considering multiple-crop samples,with R^(2)and RMSE of 0.62 and 1..26%,***,TDDI proved more effective than the CWSI in e

关键词： maize sorghum T_(s)-T_(a)-VIs CWSI UAV machine learning crop moisture monitoring

Application of Natural Medicinal Plants Active Ingredients in Oral Squamous Cell Carcinoma

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Integrative Medicine 2024年第9期30卷 852-864页

作者： REN Qun-li LI Xiao-lan TIAN Tian LI Shuang SHI Rong-yi WANG Qian ZHU Yuan WANG Miao HU Huan LIU Jian-guo School of Stomatology Zunyi Medical UniversityZunyiGuizhou Province563000China Microbial Resources and Drug Development Key Laboratory of guizhou Tertiary Institution Zunyi Medical UniversityZunyiGuizhou Province563000China School of Basic Medicine Zunyi Medical UniversityZunyiGuizhou Province563000China

Oral squamous cell carcinoma(OSCC)is the most common malignant cancer of the head and neck,with high morbidity and mortality,ranking as the sixth most common cancer in the *** treatment of OSCC is mainly radiotherapy,chemotherapy and surgery,however,the prognosis of patients is still poor and the recurrence rate is *** paper reviews the range of effects of natural medicinal plant active ingredients(NMPAIs)on OSCC cancer,including the types of NMPAIs,anti-cancer mechanisms,involved signaling pathways,and clinical *** NMPAIs include terpenoids,phenols,flavonoids,glycosides,alkaloids,coumarins,and volatile *** active ingredients inhibit proliferation,induce apoptosis and autophagy,inhibit migration and invasion of OSCC cells,and regulate cancer immunity to exert anti-cancer *** mechanism involves signaling pathways such as mitogen-activated protein kinase,phosphatidylinositol 3 kinase/protein kinase B,nuclear factor kappa B,miR-22/WNT1.β-catenin and Nrf2/***,NMPAIs can inhibit the growth of OSCC,and the combined drug is more *** medicinal plants are promising candidates for the treatment of OSCC.

关键词： natural medicinal plant active ingredients oral squamous cell carcinoma mechanism signaling pathway review

Luminescence properties and optical sensing behaviors of Sr_(2)GdSbO_(6):Eu^(3+) phosphors

在线全文

学校读者我要写书评

暂无评论

Journal of Rare Earths 2024年第8期42卷 1458-1469,I0002页

作者： Youfa Tai Ruirui Cui Jun Zhang Chunkai Wang Tingyu Zhao Beiqiao Zhang Chaoyong Deng Key Laboratory of Functional Composite Materials of guizhou Province College of Big Data and Information EngineeringGuizhou UniversityGuiyang550025China College of Computer and Information Engineering Guizhou University of CommerceGuiyang550014China School of Electronics and Information Engineering Guiyang UniversityGuiyang550005China

Novel orange-red Sr_(2)GdSbO_(6):xEu^(3+)(x=0,0.05,0.1.0.2,0.3,0.4,0.5 and 0.6) phospho rs were successfully prepared by the traditional high-temperature solid-state *** results of Rietveld refinement,energy dispersive spectroscopy(EDS) spectrum and elemental mapping demonstrate that Eu^(3+) successfully replaces the Gd^(3+) sites and distributes uniformly in the particles of *** luminescence properties of Sr_(2)GdSbO_(6):Eu_(3+)phosphors were investigated in *** emission spectra of the strongest emission peak is the ^(5)D_(0)→^(7)F_(1.(593 nm) transition,which can emit orange-red light under393 nm *** the doping concentration of Eu3+ions is x=0.2,the luminescence intensity of the phosphors reaches the *** detailed mechanism of concentration quenching is attributed to dipole-dipole *** thermal stability values of Sr_(2)GdSbO_(6):0.2Eu^(3+) phosphors are 87%,82% and1.4% under 393,467 and 527 nm excitations,*** causes of the abnormal thermal quenching under 527 nm excitation were *** on the abnormal thermal quenching under527 nm excitation,the optical thermometry properties of Sr_(2)GdSbO_(6):0.2Eu^(3+)phosphors were investigated by fluorescence intensity ratio(FIR) technique,and appreciable relative sensitivity was *** results suggest that Sr_(2)GdSbO_(6):0.2Eu^(3+)phosphors can be potentially applied to w-LEDs and optical thermometers.

关键词： Sr_(2)GdSbO_(6):Eu^(3+) Phosphors Luminescence properties Abnormal thermal quenching Rare earths

Circadian disturbance induces erectile dysfunction by impairing endothelial function

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2024年第2期26卷 205-211页

作者： Tao Li Yi-Ting Jiang Xin-Zhu Qi Peng Chen Jun-Hao Zhang Fu Luo Jun Qiao Jiang Gu Guang-Shi Du Qiang Wang Department of Urology Affiliated Hospital of Guizhou Medical UniversityGuiyang 550004China Department of Urology Guizhou Provincial People's HospitalGuiyang 550002China Department of Otorhinolaryngology Affiliated Hospital of Guizhou Medical UniversityGuiyang 550004China guizhou Institute for Food and Drug Control Guiyang 550004China Department of Reproductive Center Guizhou Provincial People's HospitalGuiyang 550002China Translational Medicine Research Center of guizhou Medical {1. Guiyang 550025China

In order to explore the impact of circadian disturbance on erectile function,we randomly divided 24 adult male rats into groups of control(light on at 8:00 *** off at 8:00 p.m.),dark/dark(DD;constant dark),light/light(LL;constant light),and shift dark/light(DL;light off at 8:00 *** on at 8:0o p.m.).Four weeks later,erectile function was measured and corpora cavernosa were harvested for *** maximum intracavernous pressure(mlcP)and mCP/mean arterial pressure(MAP)ratio in the DD,LL,and DL groups were significantly lower than that in the control *** LL and DL groups showed significantly attenuated endothelial nitric oxide synthase(eNOS),while DD,LL,and DL showed reduced neuronal nitric oxide synthase(nNOS)at both mRNA and protein *** production of nitric oxide(NO)and cyclic guanosinemonophosphate(cGMP)was inhibited by altered light/dark cycles to varying *** disturbance impaired endothelial function and contributed to erectile *** the core circadian elements,mRNA expression of circadian locomotor output cycles kaput(Clock)and brain/muscle aryl-hydrocarbon receptor nuclear translocator-like protein 1.Bmal1.was elevated in the DL group,but their protein expression was not significantly ***,LL,and DL increased period 1.Per1.and Per3 levels,while LL and DL increased PER1.*** significant difference was found for Per2levels,and PER2 and PER3 concentrations were not significantly ***,LL and DL significantly increased cryptochrome-1.CRY1.and CRY2 at both mRNA and protein *** altered light/dark rat model showed that circadian disturbance contributed to erectile dysfunction probably by impairing endothelial ***,the core circadian elements were detected in the corpora cavernosa,but these were ***,which circadian element regulates erectile function and how it works need further analysis.

关键词： circadian disturbance endothelial function erectile function light/dark cycle NO/cGMP

NMR-based analysis of the effect of moisture migration on sandstone pore structure under alternating wetting and drying conditions

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Mining Science and Technology 2024年第8期34卷 1135-1150页

作者： Huasu Wang Jing Bi Yu Zhao Chaolin Wang Jiabao Ma College of Civil Engineering Guizhou UniversityGuiyang 550025China

The wetting-drying(W-D)cycle is a type of water–rock *** pore structure of rock,such as shape,size,distribution and pore throat,affects fluid storage and *** theory and experimental research on the evolution characteristics of pore damage during the wet-dry erosion process are highly important for determining W-D *** mass and velocity of liquid migration are related to the pore size,porosity,fluid properties,*** data show that the water absorption quality and velocity in rocks decrease with the number of wet-dry *** the same test time,the mass and velocity of the SI water absorption method are smaller than those of the FI *** these two conditions,the amount and rate of water absorption represent the degree of water–rock *** the pore evolution during the wet-dry cycling,an equation describing the motion of liquid in porous media was derived based on the imbibition-type separation *** experimental data are in excellent agreement with the calculated values of the *** characteristics can affect the area and degree of rock deterioration as well as the development rate of pores and *** on the interaction between permeability and pores,quantitative analysis of the weakening process(local damage)of rocks under W-D cycles can provide good reference indicators for evaluating the stability of geotechnical engineering.

关键词： W-D cycle Capillary absorption Pore characteristic Fractal theory Dynamic damage model

ρ-meson longitudinal leading-twist distribution amplitude revisited and the D→ρsemileptonic decay

在线全文

学校读者我要写书评

暂无评论

Chinese Physics C 2024年第6期48卷 82-91页

作者：钟涛代亚红付海冰 Department of Physics Guizhou Minzu UniversityGuiyang 550025China

Motivated by our previous study[***.D 1.4(1.,01.021.2021.]on the pionic leading-twist distribution amplitude(DA),we revisit theρ-me son leading-twist longitudinal DAφ_(2;ρ)^(‖)(x,μ)in this study.A model proposed by Chang based on the DYyson-Schwinger equations is adopted to describe the behavior ofφ_(2;ρ)^(‖)(x,μ).However,theξ-moments ofφ_(2;ρ)^(‖)(x,μ)are calculated with the QCD sum rules in the framework of the background field *** sum rule formulas for these moments are *** accurate values for the first five nonzeroξ-moments at the typical scaleμ=(1.0,1.4,2.0,3.0)GeV are given,e.g.,atμ=1.GeV,(ξ^(2))>_(2;ρ)^(‖)=0.220(6),(ξ^(4))>_(2;ρ)^(‖)=0.1.3(4),(ξ^(6))>_(2;ρ)^(‖)=0.066(5),(ξ^(8))>_(2;ρ)^(‖)=0.046(4),and(ξ^(1.))>_(2;ρ)^(‖)=0.035(3).By fitting these values with the least squares method,the DSE model forφ_(2;ρ)(x,μ)is *** taking the left-handed current light-cone sum rule approach,we obtain the transition form factor in the large recoil region,i.e.,A_(1.(0)=0.498_(-0.01.)^(+0.01.),A_(2)(0)=0.460_(-0.047)^(+0.055),and V(0)=0.800_(-0.01.)^(+0.01.),and the ratio r_(2)=0.923_(-0.1.9)^(+0.1.3),rV=1.607_(-0.071.^(+0.071..After extrapolating with a rapidly converging series based on z(t)-expansion,we present the|V_(cd)|-independent decay width for the semileptonic decays D→ρ^(l+)v_(l).Finally,the branching fractions are B(D^(0)→ρ^(-)e+v_(e))=1.825_(-0.1.2)^(+0.1.0)±0.004,B(D^(+)→ρ^(0)e+v_(e))=2.299_(-0.204)^(+0.21.)±0.01.,B(D^(0)→ρ^(-)μ^(+)v_(μ))=1.81._(-0.1.0)^(+0.1.8)±0.004,and B(D^(+)→ρ^(0)μ+v_(μ))=2.288_(-0.201.^(+0.21.)±0.01..

关键词： QCD sum rule charmed meson semileptonic decay Rho meson light-cone distribution amplitude

Industrial Carbon Emission Distribution and Regional Joint Emission Reduction:A Case Study of Cities in the Pearl River Basin,China

在线全文

学校读者我要写书评

暂无评论

Chinese Geographical Science 2024年第2期34卷 210-229页

作者： JIANG Hongtao YIN Jian ZHANG Bin WEI Danqi LUO Xinyuan DING Yi XIA Ruici Center for Western China Modernization Guizhou University of Finance and EconomicsGuiyang 550025China College of Big Data Application and Economic Guizhou University of Finance and EconomicsGuiyang 550025China Key Laboratory of Green Fintech Guizhou University of Finance and EconomicsGuiyang 550025China

China’s low-carbon development path will make significant contributions to achieving global sustainable development *** to the diverse natural and economic conditions across different regions in China,there exists an imbalance in the distribution of car-bon ***,regional cooperation serves as an effective means to attain low-carbon *** study examined the pattern of carbon emissions and proposed a potential joint emission reduction strategy by utilizing the industrial carbon emission intens-ity(ICEI)as a crucial *** utilized social network analysis and Local Indicators of Spatial Association(LISA)space-time trans-ition matrix to investigate the spatiotemporal connections and discrepancies of ICEI in the cities of the Pearl River Basin(PRB),China from 201. to *** primary drivers of the ICEI were determined through geographical detectors and multi-scale geographically weighted *** results were as follows:1.the overall ICEI in the Pearl River Basin is showing a downward trend,and there is a significant spatial imbalance.2)There are numerous network connections between cities regarding the ICEI,but the network structure is relatively fragile and unstable.3)Economically developed cities such as Guangzhou,Foshan,and Dongguan are in the center of the network while playing an intermediary role.4)Energy consumption,industrialization,per capita GDP,urbanization,science and techno-logy,and productivity are found to be the most influential variables in the spatial differentiation of ICEI,and their combination in-creased the explanatory power of the geographic variation of ***,through the analysis of differences and connections in urban carbon emissions under different economic levels and ICEI,the study suggests joint carbon reduction strategies,which are centered on carbon transfer,financial support,and technological assistance among cities.

关键词： industrial carbon emission intensity carbon emission social network analysis Location Indicators of Spatial Association(LISA) geographical detector multi-scale geographically weighted regression Pearl River Basin(PRB),China

Small moleculeα-methylene-γ-butyrolactone,an evolutionarily conserved moiety in sesquiterpene lactones,ameliorates arthritic phenotype via interference DNA binding activity of NF-κB

在线全文

学校读者我要写书评

暂无评论

Acta Pharmaceutica Sinica B 2024年第8期14卷 3561-3575页

作者： Kegang Linghu Wenqing Cui Taiqin Li Yueting Tuo Dasong Wang Huiqi Pan Tian Zhang Ligen Lin Hua Yu Xiaoxia Hu Haiyang Li Xiangchun Shen Department of Surgery the Affiliated Hospital of Guizhou Medical UniversityGuiyang 550001China The Key Laboratory of Optimal Utilization of Natural Medicine Resources School of Pharmaceutical SciencesGuizhou Medical UniversityGuian New DistrictGuizhou 561113China State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoMacao SAR 999078China guizhou Institute of Precision Medicine Affiliated Hospital of Guizhou Medical UniversityGuiyang 550001China

Rheumatoid arthritis(RA)is an inflammatory disease accompanied by abnormal synovial microenvironment(SM).Sesquiterpene lactones(SLs)are the main anti-inflammatory ingredients of many traditional herbs utilized in RA treatment.α-Methylene-γ-butyrolactone(α-M-γ-B)is a core moiety that widely exists in natural *** study was designed to investigate the anti-arthritic potential ofα-M-γ-B as an independent small molecule in vitro and in vivo.α-M-γ-B exhibited stronger electrophilicity and anti-inflammatory effects than the other six analogs.α-M-γ-B inhibited the production of pro-inflammatory mediators via repolarizing M1.macrophages into M2 *** transcriptome sequencing suggested thatα-M-γ-B regulated the immune system ***,α-M-γ-B attenuated collagen type II-induced arthritic(CIA)phenotype,restored the balance of Tregs-macrophages and remodeled SM via repolarizing the synovial-associated macrophages in CIA ***,althoughα-M-γ-B did not prevent the trans-nucleus of NF-κB it interfered with the DNA binding activity of NF-κB via direct interaction with the sulfhydryl in cysteine residue of NF-κB p65,which blocked the activation of NF-κ*** of NF-κB reduced the M1.polarization of macrophage and suppressed the synovial hyperplasia and angiogenesis.α-M-γ-B failed to ameliorate CIA in the presence of N-acetylcysteine or when the mice were subjected to the macrophage-specific deficiency of *** conclusion,α-M-γ-B significantly attenuated the CIA phenotype by directly targeting NF-κB p65 and inhibiting its DNA binding *** results suggest thatα-M-γ-B has the potential to serve as an alternative candidate for treating *** greater electrophilicity ofα-M-γ-B,the basis for triggering strong anti-inflammatory activity,accounts for the reason whyα-M-γ-B is evolutionarily conserved in the SLs by medical plants.

关键词： a-Methylene-gbutyrolactone Rheumatoid arthritis NF-κB p65 Synovial microenvironment Sesquiterpene lactones

Cerium oxide inclusion nucleation mechanism based on classical nucleation theory and two-step nucleation

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Rare Earths 2024年第4期42卷 793-802页

作者： Yutang Li Jun Wang Linzhu Wang Chaoyi Chen Shufeng Yang Junqi Li Xiang Li School of Materials and Metallurgy Guizhou UniversityGuiyang550025China State Key Laboratory of Public Big Data Guizhou UniversityGuiyang550025China School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing100083China Department of Materials&Metallurgy Engineering Guizhou Institute of TechnologyGuiyang550003China

It is challenging to assess the mechanism responsible for the nucleation of inclusions in metals at high *** present work therefore systematically investigates the nucleation of cerium oxide inclusions according to classical nucleation theory and a two-step nucleation *** nucleation rates and nucleation radii of these inclusions are obtained,and the results demonstrate a considerable difference between theoretical and experimental *** the basis of a two-step nucleation mechanism,(CeO_(2))_(n) and(Ce_(2)O_(3))_(n)(n=1.6)clusters were constructed and the thermodynamic properties of both these clusters and of cerium oxide nanoparticles were *** addition,the entropies and heat capacity changes of cerium oxides were determined using first principles calculations and are found to be consistent with literature *** present data indicate that the cerium oxide inclusion nucleation pathway can be summarized as[Ce]+[O]→(CeO_(2))n/(Ce_(2)O_(3))_(n)→(Ce_(2)O_(3))_(n)→(Ce_(2)O_(3))_(2)→core(Ce_(2)O_(3)crystal)-shell((Ce_(2)O_(3))_(2) cluster)nanoparticles→(Ce_(2)O_(3))bulk.

关键词： Cerium oxide inclusion Classical nucleation theory Two-step nucleation mechanism First principles Rare earths