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tRNA^(Glu)-derived fragments from embryonic extracellular vesicles modulate bovine embryo hatching

Journal of Animal Science and Biotechnology 2024年第4期15卷 1559-1566页

作者： Yuan Fan Krishna Chaitanya Pavani Katrien Smits Ann Van Soom Luc Peelman Department of Veterinary and Biosciences Faculty of Veterinary MedicineGhent UniversityHeidestraat 199820 MerelbekeBelgium Department of Internal Medicine Reproduction and Population MedicineFaculty of Veterinary MedicineGhent UniversitySalisburylaan 1339820 MerelbekeBelgium Department for Reproductive Medicine Ghent University HospitalCorneel Heymanslaan 109000 GhentBelgium

Transfer RNA-derived small RNAs(tsRNAs)have been shown to be involved in early embryo development and repression of endogenous retroelements in embryos and stem ***,it is unknown whether tsRNAs also regulate embryo *** this study,we mined the sequencing data of a previous experiment in which we demonstrated that the microRNA(miRNA)cargo of preimplantation embryonic extracellular vesicles(EVs)influences embryo *** thus profiled the tsRNA cargo of EVs secreted by blastocysts and *** majority of tsRNAs was identified as tRNA halves originating from the 5'ends of *** the 148 differentially expressed tsRNAs,the 19 nt tRNA fragment(tRF)tDR-14:32-Glu-CTC-1 was found to be significantly up-regulated in EVs derived from ***-qPCR assays confirmed its significant up-regulation in non-blastocyst embryos and their conditioned medium compared to the blastocyst group(P14:32-Glu-CTC-1 by supplementing antagomirs to the conditioned medium improved embryo hatching(P14:32-Glu-CTC-1 antagomirs further showed differential expression of genes that are associated with embryo hatching and *** summary,tDR-14:32-Glu-CTC-1 is up-regulated in non-blastocyst embryos and their secretions,and inhibition of tDR-14:32-Glu-CTC-1 promotes embryo hatching,while influencing embryo implantation-related genes and *** results indicate that embryonic EVs containing specific tRFs may regulate preimplantation embryo development.

关键词： Embryo Extracellular vesicles Hatching tRNA fragments ts RNAs

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窗外的风景线

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作文大王(中高年级) 2024年第5期 38-39页

作者：王艺皓河南省南阳市油田第五小学503班

太神奇了!旅游归来,窗外的绿萝上竟多了个鸟窝。这鸟儿真好看,灰色的脖子后面有一小片黑色,黑色上还有白色的斑点,好像散发着光芒的萤火虫,又像姑娘的花手绢。它的腹部是白色的,像一朵白云。它的爪子鲜红鲜红的。鸟窝是用极细的小树枝...

太神奇了!旅游归来,窗外的绿萝上竟多了个鸟窝。这鸟儿真好看,灰色的脖子后面有一小片黑色,黑色上还有白色的斑点,好像散发着光芒的萤火虫,又像姑娘的花手绢。它的腹部是白色的,像一朵白云。它的爪子鲜红鲜红的。鸟窝是用极细的小树枝编成的,像一顶黄色的帽子。它是一只斑鸠。看着它卧在窝里不动,我猜它一定在孵蛋。趁斑鸠不在,我小心翼翼地拉开窗户,确定安全后,看、摸、扒、找、翻、

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Unconfined compressive strength and failure behaviour of completely weathered granite from a fault zone

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Journal of Mountain Science 2024年第6期21卷 2140-2158页

作者： DU Shaohua MA Jinyin MA Liyao ZHAO Yaqian School of Civil Engineering and Architecture Henan University of Science and TechnologyLuoyang 471023China School of Resources and Safety Engineering Central South UniversityChangsha 410083China China Railway 18th Bureau Group Co. LtdTianjin 300222 China China General Nuclear Power Corporation Shenzhen 518031China

Understanding the strength characteristics and deformation behaviour of the tunnel surrounding rock in a fault zone is significant for tunnel stability *** this study,a series of unconfined compression tests were conducted to investigate the mechanical characteristics and failure behaviour of completely weathered granite(CWG)from a fault zone,considering with height-diameter(h/d)ratio,dry densities(ρd)and moisture contents(ω).Based on the experimental results,a regression mathematical model of unconfined compressive strength(UCS)for CWG was developed using the Multiple Nonlinear Regression method(MNLR).The research results indicated that the UCS of the specimen with a h/d ratio of 0.6 decreased with the increase ofω.When the h/d ratio increased to 1.0,the UCS increasedωwith up to 10.5%and then ***ρd is conducive to the improvement of the UCS at anyω.The deformation and rupture process as well as final failure modes of the specimen are controlled by h/d ratio,ρd andω,and the h/d ratio is the dominant factor affecting the final failure mode,followed byωandρ*** specimens with different h/d ratio exhibited completely different fracture mode,i.e.,typical splitting failure(h/d=0.6)and shear failure(h/d=1.0).By comparing the experimental results,this regression model for predicting UCS is accurate and reliable,and the h/d ratio is the dominant factor affecting the UCS of CWG,followed byρd and thenω.These findings provide important references for maintenance of the tunnel crossing other fault fractured zones,especially at low confining pressure or unconfined condition.

关键词： Fault fracture zone Completely weathered granite(CWG) Unconfined compression strength(UCS) Multiple nonlinear regression model

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拼来的精彩

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好作文 2024年第10期 36-37页

作者：孙雨晴山东省平邑赛博中学八年级19班

“恰同学少年,风华正茂。”是啊,青春,一个让人想到就觉得无比热烈浪漫的词汇。青春时期,少年见到更广阔的天地,少年学习更有趣深奥的知识,少年逐渐成长,从此,少年有了理想,并以昂扬的姿态、百倍的信心和努力拼搏的精神向着理想进发。...

“恰同学少年,风华正茂。”是啊,青春,一个让人想到就觉得无比热烈浪漫的词汇。青春时期,少年见到更广阔的天地,少年学习更有趣深奥的知识,少年逐渐成长,从此,少年有了理想,并以昂扬的姿态、百倍的信心和努力拼搏的精神向着理想进发。父亲总对我说:“读万卷书,更要行万里路。”打我记事起,父亲一放下工作,便计划着带我去旅行。我们一起去到上海,感受“魔都”的魅力。

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Plant RNA-binding proteins:Phase separation dynamics and functional mechanisms underlying plant development and stress responses

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Molecular Plant 2024年第4期17卷 531-551页

作者： Sheng Fan Yu Zhang Shaobo Zhu Lisha Shen Temasek Life Sciences Laboratory 1 Research LinkNational University of Singapore1 Research LinkSingapore 117604Singapore Department of Biological Sciences National University of Singapore14 Science Drive 4Singapore 117543Singapore

RNA-binding proteins(RBPs)accompany RNA from synthesis to decay,mediating every aspect of RNA metabolism and impacting diverse cellular and developmental processes in *** RBPs undergo phase separation along with their bound RNA to form and function in dynamic membraneless biomolecular condensates for spatiotemporal coordination or regulation of RNA *** evidence suggests that phase-separating RBPs with RNA-binding domains and intrinsically disordered regions play important roles in plant development and stress ***,we summarize the current knowledge about how dynamic partitioning of RBPs into condensates controls plant development and enables sensing of experimental changes to confer growth plasticity under stress conditions,with a focus on the dynamics and functional mechanisms of RBP-rich nuclear condensates and cytoplasmic granules in mediating RNA *** also discuss roles of multiple factors,such as environmental signals,protein modifications,and N6-methyladenosine RNA methylation,in modulating the phase separation behaviors of RBPs,and highlight the prospects and challenges for future research on phase-separating RBPs in crops.

关键词： RNA-binding proteins phase separation biomolecular condensates RNA metabolism development stress resilience

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Reasonable design a high-entropy garnet-type solid electrolyte for all-solid-state lithium batteries

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Journal of Energy Chemistry 2024年第9期96卷 414-423页

作者： Shiyu Yu Yandi Li Jiaxin Luo Daming Chen Liang Yang Yaqing Wei De Li Yuanxun Li Yong Chen State Key Laboratory of Marine Resource Utilization in South China Sea School of Materials Science1nd EngineeringHainan Provincial Key Laboratory of Research on Utilization of Si-Zr-Ti ResourcesHainan UniversityHaikou 570228HainanChina State Key Laboratory of Electronic Thin Films1nd Integrated Devices University of Electronic Science1nd Technology of ChinaChengdu 610054SichuanChina Guangdong Key Laboratory for Hydrogen Energy Technologies School of Materials Science1nd Hydrogen EnergyFoshan UniversityFoshan 528000GuangdongChina

Traditional garnet solid electrolyte(Li_(7)La_(3)Zr_(2)O_(12))suffers from low room temperature ionic conductivity,poor air stability,high sintering temperature and energy *** the development prospects of high-entropy materials with high structural disorder and strong component controllability in the field of electrochemical energy storage,herein,a novel high-entropy garnet-type oxide solid electrolyte,Li_(5.75)Ga_(0.25)La_(3)Zr_(0.5)Ti_(0.5)Sn_(0.5)Nb_(0.5)O_(12)(LGLZTSNO)was constructed by partially replacing the Li and Zr sites in Li_(7)La_(3)Zr_(2)O_(12)with Ga and Ti/Sn/Nb elements,*** experimental and density functional theory(DFT)calculation results show that the high-entropy LGLZTSNO electrolyte has preferable room temperature ion conductivity,air stability,interface contact performance with lithium anode,and the ability to suppress lithium *** to the improvement of electrolyte performance,the critical current density of Li/Ag@LGLZTSNO/Li symmetric cell was increased from 0.42 to 1.57 mA cm^(−2),and the interface area specific impedance(IASR)was reduced from 765.2 to 42.3Ωcm^(2).Meanwhile,the Li/Ag@LGLZTSNO/LFP full cell also exhibits excellent rate performance and cycling performance(148 mA h g^(−1)at 0.1 C and 124 mA h g^(−1)at 0.5 C,capacity retention up to 84.8%after 100 cycles at 0.1 C),showing the application prospects of high-entropy LGLZTSNO solid electrolyte in high-performance all solid state lithium batteries.

关键词： Garnet solid electrolyte Dual-site substitution High-entropy all solid-state lithium batteries(ASSLBs)

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Oxidation behavior and improvement in nonflammability of LPSO-type Mg–Zn–Y–Sr alloy

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Journal of Magnesium and Alloys 2024年第2期12卷 742-749页

作者： Shin-ichi Inoue Kazumasa Iwanaga Yoshihito Kawamura Magnesium Research Center Kumamoto University2-39-1 KurokamiChuo-kuKumamoto 860-8555Japan Department of Materials Science Graduate School of Science and TechnologyKumamoto University2-39-1 KurokamiChuo-kuKumamoto 860-8555Japan

Mg_(97)Zn_(1)Y_(2)alloys with high ignition temperatures were developed by adding *** addition of Sr resulted in the formation of a uniform and thin Y_(2)O_(3)***–Zn–Y alloys containing at least 0.25 at.%Sr exhibited ignition temperatures of 1270–1320 *** a result of EDS measurement,Sr was found to be concentrated in the Y_(2)O_(3)*** addition,a mixed film of MgO and Sr O formed on the outer layer in the 1.5 at.%Sr-containing Mg_(97)Zn_(1)Y_(2)*** findings suggest that the uniform and thin Y_(2)O_(3)film that maintains high soundness at high temperatures was formed owing to valence control and the formation of a protective outer oxide film.

关键词： Magnesium alloy Yttrium Strontium High-temperature oxidation Nonflammability

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Semitransparent organic photovoltaics enabled by transparent p-type inorganic semiconductor and near-infrared acceptor

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Journal of Energy Chemistry 2024年第9期96卷 351-358页

作者： Xue Yan Jiayu Wang Wei He Top Archie Dela Peña Can Zhu Hailin Yu Yingyue Hu Cenqi Yan Shengqiang Ren Xingyu Chen Zhe Wang Jiaying Wu Mingjie Li Jianlong Xia Lei Meng Shirong Lu Dewei Zhao Mikhail Artemyev Yongfang Li Pei Cheng College of Polymer Science1nd Engineering State Key Laboratory of Polymer Materials EngineeringSichuan UniversityChengdu 610065SichuanChina Department of Applied Physics The Hong Kong Polytechnic UniversityKowloonHong Kong 999077China Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Organic SolidsInstitute of ChemistryChinese Academy of SciencesBeijing 100190China College of Materials Science1nd Engineering&Engineering Research Center of Alternative Energy Materials&Devices Ministry of EducationSichuan UniversityChengdu 610065SichuanChina Department of Material Science1nd Technology Taizhou UniversityTaizhou 318000ZhejiangChina Advanced Materials Thrust Function HubThe Hong Kong University of Science1nd Technology(Guangzhou)Guangzhou 511400GuangdongChina State Key Laboratory of Advanced Technology for Materials Synthesis1nd Processing Center of Smart Materials1nd DevicesWuhan University of TechnologyWuhan 430070HubeiChina Department of Civil1nd Environmental Engineering The Hong Kong University of Science1nd TechnologyHong Kong 999077China Research Institute for Physical Chemical Problems Belarusian State UniversityMinsk 220006Belarus

Semitransparent organic photovoltaics(STOPVs)have gained wide attention owing to their promising applications in building-integrated photovoltaics,agrivoltaics,and floating *** semiconductors with high charge carrier mobility usually have planar and conjugated structures,thereby showing strong absorption in visible *** this work,a new concept of incorporating transparent inorganic semiconductors is proposed for high-performance ***(I)thiocyanate(CuSCN)is a visible-transparent inorganic semiconductor with an ionization potential of 5.45 eV and high hole *** transparency of CuSCN benefits high average visible transmittance(AVT)of *** energy levels of CuSCN as donor match those of near-infrared small molecule acceptor BTP-eC9,and the formed heterojunction exhibits an ability of exciton *** mobility of CuSCN contributes to a more favorable charge transport channel and suppresses charge *** control STOPVs based on PM6/BTP-eC9 exhibit an AVT of 19.0%with a power conversion efficiency(PCE)of 12.7%.Partial replacement of PM6 with CuSCN leads to a 63%increase in transmittance,resulting in a higher AVT of 30.9%and a comparable PCE of 10.8%.

关键词： Copper(I)thiocyanate Inorganic semiconductor Semitransparent Organic photovoltaics Charge dissociation

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洋葱君,住手!

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作文大王(中高年级) 2024年第Z1期 74-75页

作者：肖璐帆河南省南阳市油田第五小学503班

“呀！帆帆，给妈妈拿点儿卫生纸来！”我拿起纸巾，三步并作两步跑进厨房，只见妈妈泪流满面——这是怎么回事？我放学回家，妈妈笑脸相迎。“妈妈，我想吃洋葱炒鸡蛋！”我兴奋地说。“好，我给你做去。”妈妈答应道。妈妈进厨房三分...

“呀！帆帆，给妈妈拿点儿卫生纸来！”我拿起纸巾，三步并作两步跑进厨房，只见妈妈泪流满面——这是怎么回事？我放学回家，妈妈笑脸相迎。“妈妈，我想吃洋葱炒鸡蛋！”我兴奋地说。“好，我给你做去。”妈妈答应道。妈妈进厨房三分钟不到，便用“撕心裂肺”的喊声，让我给她送纸去。咦，不就是切洋葱吗？妈妈怎么了，

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Prominent removal of trace lead(Ⅱ)ions from polluted water by terephthalic acid reformed Al/Zn metal organic nanoflakes

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Particuology 2024年第1期84卷 81-88页

作者： Junhua Li Lingshu Gao Junmao Hong Xiaofeng Shi Sifang Kong Jingyu Wang Hassan Algadi Benbin Xu Zhanhu Guo School of Chemistry and Chemical Engineering North University of ChinaTaiyuan030051China School of Traffic&Environment Shenzhen Institute of Information TechnologyShenzhen518172China Department of Electrical Engineering Faculty of EngineeringNajran UniversityNajran11001Saudi Arabia Mechanical and Construction Engineering Faculty of Engineering and EnvironmentNorthumbria UniversityNewcastle Upon TyneNE18STUK

Terephthalic acid reformed Al/Zn metal organic nanoflake was prepared and functionalized with trie-thylamine(T-AlZn).Without adding terephthalic acid,there was no product of metal organic nanoflake.T-AlZn has a remarkable performance in removing trace lead(Ⅱ)ions(Pb^(2+)).The adsorption equipoise with the removal rate≥97%was reached within 35 *** removal rates of T-AlZn for Pb^(2+)declined by only 16.73%after four *** adsorption of T-AlZn for Pb^(2+)follows the Langmuir isotherms model and pseudo-second-order dynamics *** utmost adsorption competence was calculated as 215.27 mg g^(-1).The T-AlZn adsorbent exhibits a bright prospect in the adsorption for Pb^(2+)and is a considerable candidate in the disposal of industrial sewage.

关键词： Metal organic complex Nanoflake Trace level Pb^(2+) Adsorption

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