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检索条件"主题词=zCKOIS"
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One-step generation of zebrafish carrying a conditional knockoutknockin visible switch via CRISPR/Cas9-mediated intron targeting
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Science China(Life Sciences) 2020年 第1期63卷 59-67页
作者: Jia Li Hong-Yu Li Shan-Ye Gu Hua-Xing Zi Lai Jiang Jiu-Lin Du Institute of Neuroscience State Key Laboratory of NeuroscienceCAS Center for Excellence in Brain Science and Intelligence TechnologyShanghai Research Center for Brain Science and Brain-Inspired IntelligenceChinese Academy of SciencesShanghai 200031China University of Chinese Academy of Sciences Beijing 100049China Department of Anesthesiology and Surgical Intensive Care Unit Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghai 200092China School of Life Science and Technology Shanghai Tech UniversityShanghai 200031China
The zebrafish has become a popular vertebrate animal model in biomedical ***,it is still challenging to make conditional gene knockout(CKO)models in zebrafish due to the low efficiency of homologous recombination(HR).... 详细信息
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