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Prognostic value of ultrasound in early arterial complications post liver transplant

World Journal of Gastrointestinal Surgery 2024年第1期16卷 13-20页

作者： Ning-Bo Zhao Yi Chen Rui Xia Jian-Bo Tang Dong Zhao Department of Ultrasound National Clinical Research Centre for Infectious DiseaseShenzhen Third People's HospitalThe Second Affiliated Hospital of Southern University of Science and TechnologyNational Clinical Research Center for Infectious DiseaseShenzhen 518112Guangdong ProvinceChina Department of Thyroid and Hernia Surgery The Second Affiliated HospitalGuangzhou Medical UniversityGuangzhou 510000Guangdong ProvinceChina Department of Biomedical Engineering Southern University of Science and TechnologyShenzhen 51800Guangdong ProvinceChina Department of Liver Surgery and Organ Transplantation Center Shenzhen Third People's HospitalThe Second Affiliated Hospital of Southern University of Science and TechnologyNational Clinical Research Center for Infectious DiseaseShenzhen 518112Guangdong ProvinceChina

Liver transplantation is the primary therapeutic intervention for end-stage liver ***,vascular complications,particularly those involving the hepatic artery,pose significant risks to *** clinical manifestations associated with early arterial complications following liver transplantation are often *** timely intervention,these complications can result in graft fai-lure or patient ***,early diagnosis and the formulation of an op-timal treatment plan are *** examination remains the pre-dominant imaging modality for detecting complications post liver *** article comprehensively reviews common causes and clinical present-ations of early hepatic artery complications in the post-transplantation period and delineates abnormal sonographic findings for accurate diagnosis of these ***,ultrasound offers the advantages of convenience,safety,effect-iveness,and *** enables real-time,dynamic,and precise evalua-tion,making it the preferred diagnostic method for post-liver transplantation *** Liver transplantation stands as the primary therapeutic approach for end-stage liver *** advancements in surgical techniques and the application of novel immunosuppressive agents contribute to ongoing improvements in the success rate and overall survival in patients undergoing liver transplantation *** these advan-cements,vascular complications,particularly those involving the hepatic artery,pose significant risks to *** the early stages following liver transplantation(within the first 30 d),proper hepatic artery function is crucial for hepatic arterial blood *** later stages,collateral circulation,including arteries such as the phrenic artery,right gastric artery,and gastroduodenal artery,becomes important for maintaining hepatic blood *** is now understood that the establishment of effective collat

关键词： Liver transplantation vascular complication Arterial complication Ultrasound

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Effects of Puerarin on Plasma Endothelin and Serum Tumor Necrosis Factor-α in Type 2 Diabetes Mellitus Patients with vascular complications

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Chinese Journal of Integrative Medicine 2002年第3期8卷 183-185页

作者： YAO Ding-guo(姚定国) LUO Su-sheng(罗苏生) NI Hai-xiang(倪海祥) WEI Jia-ping(魏佳萍) ZHENG Cui-ying(郑翠英) Department of Endocrinology Zhejiang Provincial TCM Hospital Hangzhou 310006 Department of Endocrinology Zhejiang Provincial TCM Hospital Hangzhou 310006 Department of Endocrinology Zhejiang Provincial TCM Hospital Hangzhou 310006 Department of Endocrinology Zhejiang Provincial TCM Hospital Hangzhou 310006 Department of Endocrinology Zhejiang Provincial TCM Hospital Hangzhou 310006

Objective: To study the changes of endothelin (ET), tumor necrosis factor-α (TNF-α) before and after puerarin treatment in patients with diabetes mellitus vascular complications (DMVC). Methods: Ninety-eight DMVC patients were divided into 2 groups, they were given puerarin (n=68) and normal saline (n=30) respectively, 20 diabetic patients without vascular complications (NDMVC) were taken as control, who were also given puerarin. All the patients were treated on the basis of controlling blood glucose. Plasma ET and serum TNF-α were determined by radioimmunoassay (RIA) before and after treatment. Results: Plasma ET and serum TNF-α in DMVC got higher than that of NDMVC patients (P<0.05), and ET level was correlated with TNF-α (r=0.69, r=0.73, P<0.01). After treatment, the levels of ET and TNF-α were significantly lower than those before treatment of DMVC patients with puerarin (P<0.05). Conclusion: Puerarin could regulate the levels of plasma ET and serum TNF-α of DMVC patients, suggesting that it has the function of regulating endothelial cells.

关键词： puerarin type 2 diabetes mellitus vascular complication endothelin tumor necrosis factor-α

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Hepatic artery reconstruction in pediatric liver transplantation:Experience from a single group

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Hepatobiliary & Pancreatic Diseases International 2020年第4期19卷 307-310页

作者： Ming-Xuan Feng Jia-Xu Zhang Ping Wan Bi-Jun Qiu Li-Hong Gu Jian-Jun Zhang Qiang Xia Department of Liver Surgery Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200000China Department of Ultrasonography Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200000China

Background:The reconstruction of hepatic artery is a challenging part of the pediatric liver transplantation *** artery thrombosis(HAT)and stenosis are complications which may result in ischemic biliary injury,causing early graft lost and even ***:Two hundred and fifty-nine patients underwent liver transplantation in 2017 in a single liver transplantation *** them,225 patients were living donor liver transplantation(LDLT)and 34 deceased donor liver transplantation(DDLT).Results:In LDLT all reconstructions of hepatic artery were microsurgical,while in DDLT either microsurgical reconstruction or traditional continuous suture technique was done depending on different *** were five(1.9%)HATs:four(4/34,11.8%)in DDLT(all whole liver grafts)and one(1/225,0.4%)in LDLT(P=0.001).Four HATs were managed conservatively using anticoagulation,and 1 accepted salvage surgery with *** now,3 HAT patients remain in good condition,whereas two developed biliary *** of them needed to be re-transplanted,and the other patient died due to biliary ***:Microsurgical technique significantly improves the reconstruction of hepatic artery in pediatric liver *** risk for arterial complications is higher in *** therapy can achieve good outcome in selected HAT cases.

关键词： Pediatric liver transplantation vascular complication Hepatic artery thrombosis Microsurgery

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Variations and Clinical Significance of Coagulation and Fibrinolysis Parameters in Patients with Diabetes Mellitus

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Journal of Huazhong University of Science and Technology(Medical Sciences) 1998年第4期18卷 233-235页

作者：胡俊斌魏文宁丁桂芝袁莉刘仲萍 Institute of Hematology Tongji Medical University Wuhan Department of Endocrinology Xiehe Hospital Tongji Medical University Wuhan

We observed the changes of parameters of coagulation and fibrinolytic system in order to understand the clinical implication of these variations in type Ⅱ diabetic patients. Subjects consisted of 22 patients with type Ⅱ diabetes mellitus and 25 healthy controls. Compared with the control, activated partial thrombo-plastin time, prothrombin time were shortened in the patients. The diabetic subjects also displayed higher levels of D-dimer, serum fibrin degradation products, median concentrations of fibrinogen (3. 99 vs 2. 96 g/L, Pvascular complications had significantly higher levels of fibrinogen and D-dimer than those without diabetic angiopathy. Our data demonstrated that patients with type Ⅱ diabetes mellitus had a hypercoagulable state. We believed the activation of coagulation might contribute to the vascular complications in diabetics.

关键词： diabetes mellitus hypercoagulability vascular complication

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Prevention and treatment of hepatic artery thrombosis after liver transplantation

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Hepatobiliary & Pancreatic Diseases International 2004年第1期3卷 21-25页

作者： Shu-Sen Zheng, Zhi-Yong Yu, Ting-Bo Liang, Wei-Lin Wang, Yan Shen, Min Zhang, Xiao Xu and Jian Wu Hangzhou, China Centre of Organ Transplantation and Department o Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital of Medica College, Zhcjiang University, Hangzhou 310003, China Centre of Organ Transplantation and Department of Hepatobiliary and Pancreatic Surgery First Affiliated Hospital of Medical College Zhejiang University Hangzhou 310003 China.

BACKGROUND: Hepatic artery thrombosis (HAT) which is a serious complication after orthotopic liver transplanta- tion (OLT) remains a significant cause of graft loss. The purpose of this study was to sum up our experiences in the prevention, diagnosis and management of HAT after liver transplantation. METHODS: From April 1993 to September 2003, a total of 198 patients underwent OLT at our hospital. The hepatic artery was anastomosed using 7/0 prolane with running continuous suture in 96 patients (group 1) and with inter- rupted suture in 102 (group 2). Ultrasonography was per- formed every day in two weeks after operation and selec- tively afterwards. RESULTS: HAT occurred in 6 patients (6.3%, 6/96) of group 1, and in 1 (1%, 1/102) of group 2 (x2=4.027, P= 0.045). Six patients received emergency thrombectomy, and 1 conservative therapy but died from tumor recurrence eventually. Biliary complication developed in 3 patients af- ter thrombectomy of whom 2 died of liver failure and one waited for retransplantation. In the other 3 patients after thrombectomy, 1 died of renal failure, and 2 survived. The mortality of patients with HAT was 57.1% (4/7). CONCLUSIONS: The technique of hepatic arterial anasto- mosis is the key factor for the prevention of HAT. Routine ultrasonography is very important in early detection of HAT after OLT. Biliary complication is a severe outcome secondary to HAT.

关键词： liver transplantation hepatic artery thrombosis vascular complication ultrasonography

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Portal Pseudoaneurysm with Clots Appearing as Localized Abscess:A Trap for procedure of Ultrasound-guided Percutaneous Catheterization

Portal Pseudoaneurysm with Clots Appearing as Localized Absc...

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中国超声医学工程学会第三届全国介入超声医学学术会议

作者：章建全赵璐璐仇明第二军医大学附属长征医院

Portal aneurysm is a rare occurrence,however portal pseudoaneurysm arising from laparoscopic cholecystectomy has been far more rarely *** preferred treatment for these aneurysms is surgical *** if a portal pseudoaneurysm was misinterpreted as a focal abscess at the gallbladder fossa after cholecystectomy on the basis of patient’s clinical features and definite imaging examination,clinical decision nowadays is often the one of treating the abscess by using ultrasound-guided catheterizing *** procedure of catheterization is commonly safe but can be complicated with a life-threatening bleeding as in the present case.A 70-year old woman underwent ultrasound-guided catheterization for treating a symptomatic and imaging diagnosis based abscess developing at gallbladder fossa after laparoscopic cholecystectomy,which was finally confirmed being a portal pseudoaneurysm and required emergency surgical *** this case report we try to investigate the origination and development of her portal pseudoaneurysm,the potential relation of her clinical symptoms to the pseudoaneurysm,and as well as the imaging features leading to ***,we try to share our experience in managing the unexpected bleeding after the pseudoaneurysm was ***:laparoscopic cholecystectomy;vascular complication;portal pseudoaneurysm;infectious complication;abscess;percutaneous catheterization

关键词： laparoscopic cholecystectomy vascular complication portal pseudoaneurysm infectious complication abscess percutaneous catheterization

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