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Distinguishing of Abuse Drugs in urine and blood samples of Abusers in Iran

Journal of Pharmacy and Pharmacology 2015年第8期3卷 385-390页

作者： Rezaei-Basiri Majid Behshid Mojgan Ghazi-Khansari Mahmoud Tabatabaei Seyed Mahmoud Moradi Danesh Alilu Saleh Jabbarzadeh Aahad Mokhtari Marziyeh Bahari Afrouz Department of Pharmacology and Toxicology School of Pharmacy Tabriz University of Medical Sciences Tabriz 51999 Iran Medical Education Research Center Tabriz University of Medical Sciences Tabriz 51999 Iran Department of Medical Surgical School of Nursing and Midwifery Tabriz University of Medical Sciences Tabriz 51999 Iran Department of Pharmacology and Toxicology School of Medicine Tehran University of Medical Sciences Tehran 13111 Iran Department of Physiology Tabriz Branch lslamic Azad University Tabriz 51999 Iran Welfare Organization of East Azarbayjan Tabriz 51999 Iran

In this study, one hundred urine samples and one hundred blood samples of abusers were examined for the presence of alkaloid substances and abuse drugs in urines and bloods. These numbers of blood and urine samples referred who addicts in clinics of Welfare Organization, during of detoxification treatment or maintenance treatment were screened for abuse drugs presence. Age ranges of female patients were 35 ± 15 and age range of males patients were 42 ± 18. All patients filled questionnaire and satisfy forms too. All data were analyzed by t-test and were Anowa one way, and P 〈 0.05 was considered significant. The P value of this study was P = 0.000. In this study we conclude that among all drug analytical methods the cheapest and easiest test to screening opioids and other abuse drugs in urine and blood samples is strip test for rapid diagnosis and TLC （thin-layer chromatography） is appropriate confirmation method to drug abuse distinguishing. Also tests on blood samples have high importance as a view point of accuracy to distinguishing of drugs abuse.

关键词： Abusers urine and blood samples Strip test Thin-layer chromatography abuse drugs.

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