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Rare case of hepatocellular carcinoma metastasis to urinary bladder:A case report

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World Journal of Clinical Cases 2022年第16期10卷 5470-5478页

作者： Yohan Kim Young Seok Kim Jeong-Ju Yoo Sang Gyune Kim Susie Chin Ahrim Moon Department of Gastroenterology Soonchunhyang University Hospital BucheonBucheon B14200202Gyeonggi-doSouth Korea Division of Gastroenterology and Hepatology Department of Internal MedicineSoonchunhyang University Bucheon HospitalBucheon B14200202Gyeonggi-doSouth Korea Department of Pathology Soonchunhyang University Bucheon HospitalBucheon B14200202Gyeonggi-doSouth Korea Department of Pathology Soonchunhyang University Bucheon HospitalSoonchunhyang University College of MedicineBucheon B14200202Gyeonggi-doSouth Korea

BACKGROUND Hepatocellular carcinoma(HCC)is a primary liver cancer with high prevalence and *** are many cases of advanced HCC at the time of *** methods and prognosis are different depends on whether metastasis is ***,it is necessary to make an accurate evaluation at the time of *** metastases of HCC usually occur through hematogenous spread or through adjacent organs such as the *** to the urinary bladder alone is ***,we report a rare case of biopsy-proven solitary metastasis of HCC to the bladder in a 60-year-old *** SUMMARY A 60-year-old female patient was found to be positive for hepatitis B surface antigen by chance after abdominal ultrasonography showed abnormal ***,liver dynamic computed tomography(CT)was *** patient visited the hospital for further *** and CT showed 3.6 cm sized arterial enhancing mass in segment 5 and an infiltrative mass in segment *** patient was diagnosed with HCC through liver dynamic magnetic resonance imaging and liver ***,she underwent two transcatheter arterial chemoembolizations within five months for *** follow-up,a newly appeared bladder tumor was found on liver dynamic *** underwent transurethral resection of the bladder tumor for diagnosis and *** tissue was confirmed as metastatic *** Although rare,metastasis to urinary bladder from HCC can occur without evidence of other distant ***,regular follow-up imaging examination and clinical attention are required.

关键词： Hepatocellular carcinoma Metastasis urinary bladder Case report

Fish bone migration to the urinary bladder after rectosigmoid colon perforation

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World Journal of Gastroenterology 2014年第22期20卷 7075-7078页

作者： Min-Kyung Cho Moon-Soo Lee Hyun-Young Han Seung Hyo Woo Department of Surgery Eulji University HospitalDaejeon 302-799South Korea Department of Radiology Eulji University HospitalDaejeon 302-799South Korea Department of Urology Eulji University HospitalDaejeon 302-799South Korea

Fish bones are the most common foreign objects leading to bowel *** cases are confined to the extraluminal space without penetration of an adjacent ***,abscess formation due to the perforation of the rectosigmoid colon by a fish bone can lead to the penetration of the urinary bladder and may subsequently cause the fish bone to migrate into the urinary *** the presented case,a 42-yearold female was admitted for lower abdominal *** computed tomography(CT)demonstrated a 5cm pelvic abscess containing a thin and curvilinear foreign *** conservative management,the patient was *** 1 mo,the subject developed a mechanical *** had to be delayed due to her *** of the foreign body to the urinary bladder was shown on additional CT.A Yellowish fish bone 3.5 cm in size was removed through intraoperative *** patient was discharged 8 d after the operation without any unexpected event.

关键词： Fish bone Rectosigmoid colon perforation urinary bladder Foreign body ingestion Foreign body induced bowel perforation

A Combined Clinicopathologic Analysis of 658 Urothelial Carcinoma Cases of urinary bladder

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Chinese Medical Sciences Journal 2012年第1期27卷 24-28页

作者： Hui-zhi Zhang Chao-fu Wang Juan-juan Sun Bao-hua Yu Department of Pathology Fudan University Shanghai Cancer CenterDepartment of OncologyShanghai Medical CollegeFudan UniversityShanghai 200032China

Objective To study the clinicopathological features of patients with urothelial carcinoma of the urinary bladder (UCB), and analyze the association of clinicopathological characteristics with tumor recurrence and progression. Methods Altogether 658 UCB cases in Fudan University Shanghai Cancer Center were collected from January 2006 to December 2010. The histopathologic materials and the clinical records were reviewed. Univariate and multivariate analyses were preformed to detect the association. Results The mean age of the patients was 61.97±12.97 years (range, 20-90 years). Male to female ratio was about 5:1. A total of 517 cases (78.6%) were superficial at the time of diagnosis (stage Ta/T1). The mean follow-up period was 22.36±24.92 months. Twenty-five patients lacking follow-up information were excluded in calculating recurrence and progression rates, the recurrence rate was about 37.0% (234/633), and progression rate about 6.2% (39/633). Three variables (grade, tumor growth pattern, and pathological stage) were found to be significant risk factors for tumor progression in univariate and multivariate analyses (P<0.05). Conclusions Most of the newly diagnosed UCB cases may be superficial diseases. Grade, tumor growth pattern, and pathological stage are associated with tumor progression of UCB.

关键词： urinary bladder urothelial carcinoma tumor growth pattern recurrence progression

Glass ampoule in urinary bladder as a foreign body

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Asian Journal of Urology 2016年第2期3卷 96-98页

作者： Naloh Mibang Mohammad Shazib Faridi Md Jawaid Rahman Nameirakpam Shantajit Renthlei Lalrammuana Khumukchum Somarendra Department of Urology Regional Institute of Medical SciencesImphalManipurIndia

A wide range of objects have been inserted into the urinary bladder and *** foreign bodies in the lower genitourinary tract are self-inserted via the urethra as the result of erotic impulses,psychometric problems,sexual curiosity,or sexual practice while *** we report the case of a 32-year-old female with alleged history of insertion of glass ampoule in the urethra by the husband in eroticism which was removed with open *** is the first case of its kind as per the literature available.

关键词： Foreign body urinary bladder Glass ampoule Cystostomy

Experimental Study of the Effect of Capsaicin on the urinary bladder Function in Rats

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Journal of Huazhong University of Science and Technology(Medical Sciences) 2000年第2期20卷 116-119页

作者：袁继炎 Departments of Pediatric Surgery Tongji Medical University Wuhan

In order to investigate the effect of capsaicin (CAP) on the urinary bladder function, an in vivo whole bladder study was undertaken in 25 adult healthy Wistar rats. CAP of various concentrations was instilled into the urinary bladder, and intravesical pressure, detrusor contraction and micturition status were recorded; then the trigone of the bladder was cut off and prepared for peroxidase -antiperoxidase (PAP) immunohistochemical investigation. The changes on the distribution of Sub- stance P (SP) in control and experimental groups were compared. The results showed that the intravesical application of CAP caused a significant change in the urinary bladder function. At a low concentration of CAP there was a slight increase of maximal detrusor pressure, but at a high concentration of CAP the maximal intravesical pressure was significantly decreased and associated with urinary retention and urinary incontinence. PAP sustaining had shown a depletion of SP in CAP-treated urinary bladder in rats, and this depletion was more significant at high concentrations of CAP. Because this depletion could block C-fiber transmission, detrusor function entered, from primary excitation phase, a late inhibitory phase. This suggests that a local application of CAP into urinary bladder could be used in the treatment of neurogenic bladder (detrusor hyperreflexia) to relieve frequency, urgency, incontinence and improve renal function.

关键词： urinary bladder capsaicin substance P Wistar rat

Case Report:Diagnosis and treatment of pheochromocytoma in urinary bladder

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2007年第6期8卷 435-438页

作者： LIU Yong DONG Sheng-guo DONG Zhen MAO Xin SHI Xin-yan Department of Urology Affiliated Hospital School of Medicine Qingdao University Qingdao 266003 China

Objective： To study the diagnosis and treatment ofpheochromocytoma in urinary bladder. Methods： Six cases of bladder pheochromocytoma were studied. Four cases showed hypertension, 3 of which were paroxysmal hypertension during urination. Catecholamine （CA） was increased in a case, and vanillymandelic acid （VMA） was increased in 2 cases. bladder submucosal mass was detected by B-ultrasound in 5 cases （5/5）, computerized tomography （CT） in 3 cases （3/3）, cystoscopy in 5 cases （5/6）. Four cases took a-receptor blocker for 2 weeks, 1 case took β-receptor blocker to decrease heart rate. All patients were treated with surgical operation including 4 partial cystectomies, 2 excavations. Results： Three cases had manifestations including headache, excessive perspiration and hypertension during cystoscopy. Four cases were confirmed before operation. Two cases showed hypertension during operation. All patients were pathologically diagnosed as pheochromocytoma post- operatively. In five cases followed up, blood pressure returned to normal. No patient had relapse and malignancy. Conclusions： Typical hypertension during urination comprised the main symptoms. We should highly suspect bladder pheochromocytoma if a submucosal mass was discovered with B-ultrasound, CT, ^131I-M1BG （methyliodobenzylguanidine） and cystoscopy. The determination of CA in urine is valuable for qualitative diagnosis. The preoperative management of controlling blood pressure and expansion of the blood volume are very important. Surgical operation is a good method for effective treatment. Postoperative long-time followed up is necessary.

关键词： urinary bladder Pheochromocytoma Diagnosis Therapeutics

A novel bioreactor to simulate urinary bladder mechanical properties and compliance for bladder functional tissue engineering

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Chinese Medical Journal 2011年第4期124卷 568-573页

作者： WEI Xin LI Dao-bing XU Feng WANG Yan ZHU Yu-chun LI Hong WANG Kun-jie Department of Urology West China Hospital Sichuan UniversityChengdu Sichuan 610041 China

Background Bioreactors are pivotal tools for generating mechanical stimulation in functional tissue engineering *** study aimed to create a bioreactor that can simulate urinary bladder mechanical properties, and to investigate the effects of a mechanically stimulated culture on urothelial cells and bladder smooth muscle *** We designed a bioreactor to simulate the mechanical properties of bladder. A pressure-record system was used to evaluate the mechanical properties of the bioreactor by measuring the pressure in culture chambers. To test the biocompatibility of the bioreactor, viabilities of urothelial cells and smooth muscle cells cultured in the bioreactor under static and mechanically changed conditions were measured after 7-day culture. To evaluate the effect of mechanical stimulations on the vital cells, urethral cells and smooth muscle cells were cultured in the simulated mechanical conditions. After that, the viability and the distribution pattern of the cells were observed and compared with cells cultured in non-mechanical stimulated *** The bioreactor system successfully generated waveforms similar to the intended programmed model while maintaining a cell-seeded elastic membrane between the chambers. There were no differences between viabilities of urothelial cells （（91.90±1.22）% vs. （93.14±1.78）%, P 〉0.05） and bladder smooth muscle cells （（93.41±1.49）% vs.（92.61±1.34）%, P 〉0.05）. The viability of cells and tissue structure observation after cultured in simulated condition showed that mechanical stimulation was the only factor affected cells in the bioreactor and improved the arrangement of cells on silastic *** This bioreactor can effectively simulate the physiological and mechanical properties of the *** stimulation is the only factor that affected the viability of cells cultured in the bioreactor. The bioreactor can change the growth behavior of urothelial cells and bladder smooth muscle ce

关键词： bioreactor tissue engineering urinary bladder compliance

Diagnosis and treatment of penetrating wounds through the anorectum and urinary bladder or posterior urethra

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Chinese Medical Journal 2006年第4期119卷 339-341页

作者： LIU Xin-sheng Wang Xin ZHANG Yang-de Department of Hepatobiliary and Enteric Surgery Third Affiliated Hospital Xinxiang Medical college Xinxiang 453003 China Center of Hepatobiliary and Enteric Surgery Xiangya Hospital Changsha 410008 China

Penetrating wound of the anal canal is relatively rare, which is often complicated with injuries of the rectum, urinary bladder or posterior urethra. Misdiagnosis and improper treatments of the disease may lead to pelvic abscess, anal stenosis, fecal incontinence, or rectovesical fistula. From 1985 to 2004, 16 patients with penetrating wounds through the anorectum and urinary bladder or posterior urethra were treated in our hospital.

关键词： penetrating wound anal canal rectum urinary bladder posterior urethra

Morphological changes of cholinergic nerve fibers in the urinary bladder after establishment of artificial somatic-autonomic reflex arc in rats

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Neuroscience Bulletin 2007年第5期23卷 277-281页

作者：王晗知李淑蓉文灿肖传国苏炳银第三军医大学基础医学部神经生物学教研室重庆市神经科学研究所重庆400038 成都医学院病理学教研室华中科技大学同济医学院附属协和医院泌尿外科武汉430022 成都医学院组织胚胎与神经生物学教研室四川省发育与再生重点实验室成都610081

Objective To establish an artificial somatic-autonomic reflex arc in rats and observe the following distributive changes of neural fibers in the bladder. Methods Adult Sprague-Dawley rats were randomly divided into three groups： control group, spinal cord injury （SCI） group, and reinnervation group. DiI retrograde tracing was used to verify establishment of the model and to investigate the transport function of the regenerated efferent axons in the new reflex arc. Choline acetyltransferase （CHAT） in the DiI-labeled neurons was detected by immunohistochemistry. Distribution of neural fibers in the bladder was observed by acetylcholine esterase staining. Results DR-labeled neurons distributed mainly in the left ventral horn from L3 to L5, and some of them were also CHAT-positive. The neural fibers in the bladder detrusor reduced remarkably in the SCI group compared with the control （P 〈 0.05）. After establishment of the somatic-autonomic reflex arc in the reinnervation group, the number of ipsilateral fibers in the bladder increased markedly compared with the SCI group （P 〈 0.05）, though still much less than that in the control （P 〈 0.05）. Conclusion The efferent branches of the somatic nerves may grow and replace the parasympathetic preganglionic axons through axonal regeneration. Acetylcholine is still the major neurotransmitter of the new reflex arc. The controllability of detrusor may be promoted when it is reinnervated by the pelvic ganglia efferent somatic motor fibers from the postganglionic axons.

关键词： urinary bladder acetylcholine esterase innervation