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DISTRIBUTION AND CHARACTERIZATION OF NON-VOLATILE CHEMICAL MUTAGENS IN SEDIMRNTS OF AN INDUSTRIALLY IMPACTED RIVER

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癌变．畸变．突变 1991年第S1期3卷 177-177页

作者： M.Wilson Tabor Marcus C.Waldron Alan R.White Univ.Cinc.Med.Ctr CincinnatiOH 45267 Marshall Univ. HuntingtonWV 25701 ND State Univ.Fargo ND 58105

A coupled bioassay/analytical fractionation approachwas used to isolate genotoxic contaminants from riversediments collected at points upstream,adjacent to,and downstream from centers of major industrial andmunicipal ... 详细信息

关键词： downstream sequentially upstream fractionation extracts centers polar isolate exchanges Salmonella

Omega 3 and atrial fibrillation:Where are we?

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World Journal of Cardiology 2016年第2期8卷 114-119页

作者： Annamaria Martino Laura Pezzi Roberta Magnano Elisa Salustri Maria Penco Leonardo Calo' Division of Cardiology Policlinico Casilino Department of Cardiovascular RespiratoryNephrologic and Geriatrics SciencesUmberto I HospitalSapienza University Department of Cardiology University of l’Aquila

Anti-arrhythmic properties of n-3 polyunsaturated fatty acids, at least in part mediated by anti-oxidant, anti-inflammatory and anti-fibrotic power, have been widely proved. Effect of fish oil on atrial fibrillation, both in primary and in secondary prevention and after cardiac surgery, are controversial, mostly due to lack of homogeneity between studies but also due to individual variability in response to fatty acids administration. Inclusion of measurement of incorporation of fish oil into cell membranes, appears to be essential in future studies, to assess their antiarrhythmic effect.

关键词： N-3 polyunsaturated fatty acids Atrial fibrillation upstream therapy Omega-3 index Cardiac surgery

Differential proteomics analysis of pathogenic unit of stasis-heat for acute intracerebral hemorrhage

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China Medical Abstracts(Internal Medicine) 2019年第3期36卷 133-133页

作者： ZHANG Ning Sch Med & Life Sci Nanjing Univ Chin Med

Objective To clarify the biomarkers and molecular disorder mechanism of pathogenic unit of stasis-heat of acute intracerebral *** A total of 271 acute cerebral hemorrhage patients and their plasma samples were collected and classified into stasis-heat type and non-stasis-heat type according to Quantitative Diagnostic Scale of Stasis-heat *** 4 of each group were selected by 1∶1 paired design,and plasma samples of 4 pairs were collected or detecting differential proteins by tandem mass tag(TMT).The proteins expressed more than 1.3 times and P≤0.05 between the two groups were taken as differential *** Ingenuity Pathway Analysis(IPA)bioinformatics software was performed in analyzing canonical pathways,upstream regulatory factor,molecular cellular functions,and protein interaction network of differential *** A total of 490 proteins were identified and quantified in each patient,of which 9 proteins were differentially expressed between the two groups(A1BG,ACTN1,CA1,CD44,CP,PRDX2,VCL,IgG H chain,and IGHV3-7),and A1BG,ACTN1,CA1,CD44,CP,PRDX2,and VCL were identified by IPA *** with non-stasis-heat group,CD44 was down-regulated and the remaining six proteins were *** proteins involved 5 canonical signaling pathways,2 upstream regulators and 5 kinds of molecules and cell *** associated functional network was generated with acceptable *** Differential proteins reflecting the potential biomarkers of pathogenic unit of stasis-heat of the acute cerebral hemorrhage,are involved in the regulation of PI3K complexes,Akt and ERK-related cellular signaling pathways,which are closely related to inflammatory factors or their regulated upstream pathways.

关键词： acute hemorrhage upstream

Evolution of Alu elements toward enhancers

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Science Foundation in China 2015年第1期23卷 17-17页

*** and colleagues from CAS-MPG Partner Institute for Computational Biology published their research result entitled"Evolution of Alu elements toward enhancers"in Cell Reports(2014,7(2):376—385).Of the human genome 10%is comprised of more than one million Alu repetitive elements,whose functions remain *** this work,***’s team showed that Alus are more conserved when loca-

关键词： toward entitled conserved repetitive unclear evolutionary genomic upstream comprised enhancer

Relationship between Concentration and Location of theHerbal Industry

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Journal of Environmental Science and Engineering(B) 2019年第5期8卷 186-189页

作者： Rohana Abd Rahman Ariff Fahmi Abu Bakar Economic and Strategic Analysis Programme Forest Research Institute MalaysiaKepong Selangor 52109Malaysia

Malaysia aspires to become developed and high income nation by year 2020. Under the Tenth Malaysia Plan, herbal industry was the first Entry Point Project for Agricultural National Key Economic Area in Economic Transformation Programme. To understand the current status of the herbal industry, FRIM (Forest Research Institute Malaysia) conducted the survey on 6,923 herbal chain players, consisted from upstream to downstream activities. A face-to-face interview was conducted using a structured questionnaire to gather the information. This paper highlighted the relationship between concentration of the herbal industry and urbanization’s status of the areas. The finding shows that a statistically significant difference exists between category of herbal activities and status of the areas. The upstream activities are more concentrated in rural areas, while most of downstream activities in urban areas. It is in line with central place of theory on how settlements and places are located in relation to one another and their functions. Therefore, to further develop the herbal industry, the government should consider strategic location by category of industrial activities in policies planning, programmes implementation and providing infrastructural support needed by the industry.

关键词： upstream downstream herbal industry industrial location central place theory

The Weakening Impact of China's Rare Earth Industry on the Global Market

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China Nonferrous Metals Monthly 2008年第11期 8-8页

China boasts the richest rare earth resource in the world and is the manufacturing base of midstream and upstream *** to the statistics published by the Office for Rare Earth under the National Development and Re-

关键词： upstream thousand mines quota Russia adjustment ov

Human papillomaviruses as targets for cancer gene therapy

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中国实验血液学杂志 1997年第3期5卷 293-293页

作者： Poornima Kamath Edward J.Shillitoe Karen Adler-Storthz Department of Basic Sciences Dental BranchUniversity of Texas at HoustonDepartment of Microbiology and ImmunologyState University of New YorkCollege of MedicineDepartment of Basic SciencesDental BranchUniversity of Texas at Houston

Gene therapy of human cancer is likely to bemost effective when it is directed at targets that areexpressed in cancer cells but are lacking from othercells. Human papillomaviruses (HPV) can providesuch target, since these viruses are present in manycervical and oral cancers, and likely to be etiologicagents of the tumor. The oncogenic ability of HPVhas been assigned primarily to its two early genes, E6and E7. Continued expression of these two genes

关键词： likely assigned lacking promoter primarily directed therap transcriptase upstream alone

化学与环境工程学院任朝华博士获国际埃尼奖2016年度提名

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长江大学学报（自科版）（上旬） 2015年第11期12卷 74-74页

化学与环境工程学院任朝华博士在国际上发表的系列成果受到国际同行的关注,并受国际埃尼奖（Eni Award）科学委员会的邀请和提名,成为该奖项2016年度候选人之一。

关键词：国际埃环境工程学院 hydrocarbons downstream chemicals 省科技进步发明专利授权 upstream 性能预测中国石油