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Cerebral tuberculoma:critical review of two cases

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Asian Pacific Journal of Tropical Medicine 2008年第4期1卷 67-71页

作者： Amit Agrawal Sameer Singhal S.R.Joharapurkar S.J.Vagha Bhushan Wani Department of Surgery Datta Meghe Institute of Medical SciencesSawangi(Meghe) Wardha India Department of Medicine Datta Meghe Institute of Medical SciencesSawangi(Meghe) Wardha India Datta Meghe Institute of Medical Sciences Datta Meghe Institute of Medical SciencesSawangi(Meghe)Wardha.India Department of Pathology Datta Meghe Institute of Medical SciencesSawangi(Meghe)Wardha India Department of Surgery Datta Meghe Institute of Medical SciencesSawangi(Meghe)Wardha India

Central nervous system tuberculosis can have protean *** review the clinical and radiological findings in two cases of cerebral tuberculoma in immuoncompetent *** two cases represent the spectrum of variations of clinical and radiological features of cerebral tuberculoma and highlight the controversies in the approach to diagnosis and management.

关键词： Cerebral tuberculoma Intracerebral mass tuberculoma Tuberculosis

Hypodense cerebellar tuberculoma on CT scan masquerading low grade glioma

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Asian Pacific Journal of Tropical Medicine 2009年第1期2卷 78-79页

作者： Amit Agrawal Arvind Bhake Department of Surgery Datta Meghe Institute of Medical SciencesSawangi(Meghe)Wardha-442004MaharashtraIndia Department of Pathology Datta Meghe Institute of Medical SciencesSawangi(Meghe)Wardha-442004MaharashtraIndia

We report a case of hypodense cerebellar tuberculoma in a 26 year old postpartum lady who presented with one episode of generalized tonic-clonic seizures and discuss the histopathology findings where on CT scan the lesion was suspected as low grade *** was started on isoniazid,rifampicin,pyrazinamide,ethambutol and *** is asymptomatic and had no neurological deficits at follow up.

关键词： tuberculoma Low grade glioma Hypodense Pregnancy Cerebellum Seizures

Value of video-assisted thoracoscopic surgery in the diagnosis and treatment of pulmonary tuberculoma:53 cases analysis and review of literature

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2009年第5期10卷 375-379页

作者： Kun-Yen HSUDepartment of Thoracic Medicine Chia-Yi Christian Hospital Hwa-Chan LEE Chien-Chih OU Shi-ping LUH Department of Surgery Saint Martin De Porres Hospital Department of Thoracic Medicine Saint Martin De Porres Hospital Institute of Bioinformational Technology National Chiao-Tung University

tuberculoma of the lung is one of manifestations in tuberculosis and usually presents as a solitary pulmonary nodule(SPN).It is difficult to differentiate tuberculoma from SPN by other benign or malignant *** present,the crucial role of video-assisted thoracoscopic surgery(VATS) in diagnosis and treatment of pulmonary diseases has been well ***,we reported 53 patients undergoing VATS resection for tuberculomas in our *** postoperative mortality was found and only two patients experienced prolonged air-leakage(>7 d) and two had minor wound infections that were recovered after anti-tuber-culosis or antibiotic ***-tuberculosis chemotherapy from 6 to 12 months was routinely used *** conclude that VATS is a satisfactory tool for the diagnosis and treatment of tuberculoma and can also establish a reliable diagnosis for all patients with SPNs.

关键词： tuberculoma Video-assisted thoracoscopic surgery (VATS) Anti-tuberculosis treatment

Intrasellar tuberculoma:case report

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Chinese Medical Journal 2004年第1期117卷 153-154页

作者：孙伟建王芙昱 Department of Neurosurgery Affiliated Hospital of the Military Academy of Medical Sciences

Intrasellar tuberculoma is a rare disease that is often difficult to diagnose before surgery. We present a case of intrasellar tuberculoma treated at our department.

关键词： intrasellar tuberculoma

Evaluation of MRI in the diagnosis of hepatic tuberculoma

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Chinese Medical Journal 2004年第5期117卷 782-784页

作者：徐鹏举严福华程伟中凌志青陈财忠樊嘉纪元 Department of Radiology Department of Hepato-surgery Department of Pathology

Tuberculosis is common in developing countries but hepatic tuberculosis is rare, especially in the form of hepatic tuberculomas or macronodular tuberculoma. Most of the cases have been misdiagnosed as hepatic tumours on medical imaging.1-3 Many reports have described its magnetic resonance image (MRI) and differential diagnosis.4-11 This paper is a summary of MRI findings and analysis of 10 cases with hepatic tuberculoma.

关键词： tuberculoma liver magnetic resonance imaging

Intraventricular Hemorrhage, a Rare Complication of a Cerebral tuberculoma: Study of a Case in the Neurology Department of the University Hospital of Conakry

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Case Reports in Clinical Medicine 2023年第1期12卷 1-8页

作者： Doumbouya Idrissa Touré Mohamed Lamine Barry Djénabou Négué Diawara Karinka Traoré Mohamed Cissé Fodé Abass Department of Neurology University Hospital of Conakry Conakry Guinea

Intraventricular haemorrhage (IVH) is an extremely rare and poorly described complication of central nervous system Tuberculosis (CNS-TB). In this study, we report the case of a 42-year-old man who presented with a weakness of the left hemibody with diffuse headache, altered consciousness associated with fever. No notion of contagion was noted. Brain computed tomography (CT) showed a hematoma in the occipital horns of the lateral ventricles with peri-lesional oedema of the right hemisphere;after injection of contrast product (CP), there were ring-shaped contrasts in the occipital horn of the lateral ventricle and the right thalamus. Angioscan showed no aneurysms or vascular anomalies. Chest X-ray showed micronodular opacities less than 1.5 cm in size in relation to miliary. Xpert MTB/RIF of sputum and cerebrospinal fluid (CSF) showed Mycobacterium tuberculosis (MT). The patient’s course was favourable under antihypertensive and antitubercular treatment. Conclusion: This case illustrates the diagnostic difficulties of CNS-TB due to the polymorphism of the clinical and radiological presentation of CNS-TB.

关键词： Intraventricular Haemorrhage Tuberculosis tuberculoma

Pachymeningeal en Plaque tuberculoma in Children: A Case Report

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Open Journal of Modern Neurosurgery 2020年第1期10卷 63-69页

作者： Ibrahima Berete Alpha Boubacar Bah Seylan Diawara Mohammed Benzagmout Khalid Chakour Mohammed Faiz Chaoui Service de Neurochirurgie CHU Hassan II Fès Morocco Service de Neurochirurgie CHU Donka Conakry Guinea

Pachymeningeal en plaque tuberculoma is a rare manifestation of tuberculosis and has a poor prognosis if not diagnosed early and treated adequately. The aim of the present paper is to collect the reported clinical and radiological signs in the literature and compare it with a personal observation to evaluate the possibility of a presumptive diagnosis. A 4-year-old boy presented at the pediatric emergency department with 7 days history of severe headache, vomiting blurred vision and had one partial seizure. His neurologic examination was notable for decreased visual acuity with bilateral papilledema and intact extra-ocular muscles. His neck was rigid. Neuroimaging revealed a multifocal dural-based mass on the fronto-parietal convexity with dense heterogeneous contrast enhancement and hydrocephalus. He has undergone a Ventriculoperitoneal shunt and surgical excision of the mass the next day. Outcome was favorable with antituberculosis therapy and corticosteroids. The clinical presentation and outcome were similar to the reported cases in the literature.

关键词： tuberculoma Pachymeningeal Intracranial Tuberculosis MRI CT Scan

Infratentorial tuberculoma Mimics Tumor in Immunocompetent Adults: An Analysis of 11 Patients

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Open Journal of Modern Neurosurgery 2013年第3期3卷 36-40页

作者： Ning Guo Fan Huang Xi Chen Minying Zheng Dexia Zhong Yanqing Feng Department of Neurology Guangdong Key Laboratory for Diagnosis and Treatment of Major Neurological Diseases National Key Clinical Department and National Key Discipline The First Affiliated Hospital of Sun Yat-sen University Guangzhou China Department of Neurosurgery The First Affiliated Hospital of Sun Yat-sen University Guangzhou China Department of Rehabilitation Medicine The First Affiliated Hospital of Sun Yat-sen University Guangzhou China

Backgrounds: tuberculoma is a granulomatous inflammatory process mimicking a neoplasm, both clinically and radiologically. Although those with an infratentorial origin are rare, this disease is still a diagnostic challenge using conventional workup. However, this disease should not be overlooked because it is essentially curable with proper diagnosis and therapy, usually, a Mycobacterium Tuberculosis (MTB) DNA test is performed. Methods: We retrospectively analyzed the clinical presentations, CSF results, and images of 11 MTB DNA positive and clinically cured cases of infratentorial tuberculoma. Results: Infratentorial tuberculoma usually deteriorated before antituberculosis treatment (ATT). Magnetic resonance imaging showed space-occupying lesions without specific features, 4 within the cerebellum and 7 within the brainstem. Evidence of systemic tuberculosis was found in only 1 case. Clinical manifestations included various combinations of focal signs and symptoms in the brain stem and cerebellum. Cerebrospinal fluid (CSF) findings were also nonspecific. The diagnoses of these cases were based on the positive tests of a nested polymerase chain reaction (N-PCR) assay. Trial therapy with antituberculous drugs resulted in clinical improvement, as documented by MRI in all patients. Conclusions: Infratentorial tuberculoma should be suspected in patients with infratentorial space-occupying lesions who live in geographic areas where tuberculosis is endemic.

关键词： Infratentorial tuberculoma Tumor Diagnosis

Intraventricular tuberculoma: A case report

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Case Reports in Clinical Medicine 2013年第1期2卷 81-84页

作者： O. Coulibaly S. Diawara K. Quénum Y. Sogoba M. Boutarbouch A. Melhaoui L. Rifi Y. Arkha S. Derraz A. El Ouahabi A. El Khamlichi Department of Neurosurgery CHU IbnSina Rabat Morocco

Intracranial tuberculomas are one of the most serious formsof tuberculosis disease after meningitis tuberculosis. It incidence varies around 0.15% - 0.18% in the development world to 5% - 30% of intracranial masses in some under developments areas. These tuberculomas, of course ubiquitous, are mostly diagnosed in the adulthood and usually located in the cerebellum and the cerebral hemispheres. Intra ventricular involving is uncommon and just 10 cases had been described in the literature. We report a case of an intraventricular tuberculoma in a 26- year-old man and we discuss the pathogenesis and the radiological findings according this location.

关键词： Intracranial Tuberculosis Intraventricular tuberculoma Antituberculous Treatment