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tripartite *** 3(TRIM3)inhibits tumor growth and metastasis of liver cancer

Chinese Journal of Cancer 2017年第9期36卷 407-419页

作者： Xu.Qiong Huang Xiao.Fei Zhang Jin.Hua Xia Jie Chao Qiu.Zhong Pan Jing.Jing Zhao Zi.Qi Zhou Chang.Long Chen Yan Tang De.Sheng Weng Jian.Hua Zhang Jian.Chuan Xia Department of Biotherapy State Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineSun Yat-sen University Cancer CenterGuangzhou 510060GuangdongP.R.China Department of Epidemiology and Health Statistics Guangdong Pharmaceutical UniversityGuangzhou 510010GuangdongP.R.China Guangzhou Health Science College Guangzhou 510925GuangdongP.R.China Shanxi Entry-Exit Inspection and Quarantine Bureau Xi’an 710068ShanxiP.R.China.

Background:Reduced expression of tripartite motif-containing 3(TRIM3) has been reported to be involved in the pathogenesis of human *** our previous research,we found that TRIM3 expression was markedly reduced in human primary hepatocellular carcinoma(HCC) tissues and that low TRIM3 expression was associated with short survival of HCC ***,the role of TRIM3 in liver cancer remains *** study aimed to investigate the function of TRIM3 in liver cancer ***:The protein levels of TRIM3 in five liver cancer cell lines(SK-Hep1,Hep3 B,Huh7,HepG2,Bel-7402) and one normal liver cell line(L02) were detected with Western ***2 and Bel-7402 cells with low TRIM3 expression were infected with recombinant lentiviruses overexpressing TRIM3(LV-TRIM3),whereas Huh7 and Hep3 B cells with high TRIM3 expression were transfected with TRIM3-targeted small interfering RNA(siTRIM3).The functions of TRIM3 in the proliferation,colony formation,cell cycle,migration,invasion,and apoptosis of the above cell lines were *** effect ofTRIM3 on tumor growth and metastases in nude mice was also ***:TRIM3 was overexpressed in HepG2 and Bel-7402 cells with LV-TRIM3 infection,which further reduced proliferation,colony formation,migration,and invasion of both cell *** cycle analysis showed that TRIM3 overexpression induced G_0/G_1 phase arrest in HepG2 and Bel-7402 ***,apoptosis was not increased in HepG2 or Bel-7402 cells overexpressing ***,silencing TRIM3 expression in Huh7 and Hep3 B cells by siTRIM3 led to significantly decreased percentages of both cells in the G_0/G_1 phase and promoted cell proliferation,colony formation,migration,and *** vivo experiment results confirmed that TRIM3 overexpression suppressed tumor growth and ***:TRIM3 plays a tumor-suppressing role in the regulation of liver cancer development by reducing cell proliferation through cell cycle arrest a

关键词： tripartite motif-containing 3 (TRIM3) Liver cancer Tumor suppressor Cell cycle

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The Coordination Mechanism of Supply Chain Finance Based on tripartite Game Theory

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Journal of Shanghai Jiaotong university(Science) 2016年第3期21卷 370-373页

作者：赵金实段永瑞 School of Finance and Business Shanghai Normal University Business School Columbia University College of Economics and Management Tongji University

Supply chain finance(SCF) is concerned because of its service efficiency for the real economy. Beside the bank, some enterprises have provided the SCF service. E-commerce platform firms develop small and micro loan system in China. A given small enterprise can apply for a loan through its platform. Based on the latest SCF developments and the relevant literature, this study focuses on the coordination mechanism of SCF. We construct a game theory model including supplier, retailer and financial service provider to analyze the decision making of them. We find the optimal solution to the supplier, retailer and financial service provider.

关键词： supply chain finance(SCF) coordination mechanism tripartite game supply chain

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tripartite Entanglement and Lorentz Transformation

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Journal of Quantum Information Science 2014年第3期4卷 173-193页

作者： Firouz Amiri Shahpoor Moradi Department of Physics Razi University Kermanshah Iran Department of Physics Islamic Azad University Khorram Abad Branch Khorramabad Iran

Entanglement of tripartite spin states under Lorentz transformations is studied in the context of Bell’s inequality and positive partial transpose criterion. First the relativistic analogue of Bell’s inequality is discussed for three qubit states by explicit calculation of the Wigner rotation. We use the relativistic invariant spin operator which is related to the Pauli-Lubanski pseudo vector. For observers at rest the Bell’s inequality is speed-independent and maximally violated. For moving observers it’s shown that Bell’s inequality is violated and the amount of violation depends on the boost speed. We show that in ultrarelativistic limit Bell’s inequality is still maximally violated. We also obtained the critical value for satisfying Bell’s inequality. The critical value of boost speed for violation of inequality for particles moving in the center of mass frame is greater than that for particles moving with the same momentum. Second we investigate the entanglement distillability of tripartite mixed spin states under Lorentz transformations in the context of Werner states. We show that there are states that will change from distillable (entangled) into separable for a certain value of rapidity.

关键词： Wigner Rotation Bell’s Inequality tripartite Entanglement

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Astrocyte-Synapse Receptor Coupling in tripartite Synapses: A Mechanism for Self-Observing Robots

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Advances in Bioscience and Biotechnology 2018年第2期9卷 63-82页

作者： Bernhard J. Mitterauer Volitronics-Institute for Basic Research Psychopathology and Brain Philosophy University of Salzburg Salzburg Austria

A model of an intentional self-observing system is proposed based on the structure and functions of astrocyte-synapse interactions in tripartite synapses. Astrocyte-synapse interactions are cyclically organized and operate via feedforward and feedback mechanisms, formally described by proemial counting. Synaptic, extrasynaptic and astrocyte receptors are interpreted as places with the same or different quality of information processing described by the combinatorics of tritograms. It is hypothesized that receptors on the astrocytic membrane may embody intentional programs that select corresponding synaptic and extrasynaptic receptors for the formation of receptor-receptor complexes. Basically, the act of self-observation is generated if the actual environmental information is appropriate to the intended observation processed by receptor-receptor complexes. This mechanism is implemented for a robot brain enabling the robot to experience environmental information as “its own”. It is suggested that this mechanism enables the robot to generate matches and mismatches between intended observations and the observations in the environment, based on the cyclic organization of the mechanism. In exploring an unknown environment the robot may stepwise construct an observation space, stored in memory, commanded and controlled by the intentional self-observing system. Finally, the role of self-observation in machine consciousness is shortly discussed.

关键词： tripartite Synapse Cyclic Organization Receptor Coupling Self-Observation Conscious Robots

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A biotrophic fungal infection of the great burnet Sanguisorba officinalis indirectly affects caterpillar performance of the endangered scarce large blue butterfly Phengaris teleius

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Insect Science 2019年第3期26卷 555-568页

作者： Ewa B. Sliwinska Ratal Martyka Miroslaw Martyka Mariusz Cichon Piotr Tryjanowski Institute of Nature Conservation Polish Academy of Sciences Krakow Poland Institute of Mathematical and Natural Science State Higher Vocational School in Tarnow Tarnow Poland Institute of Environmental Sciences Jagiellonian University Krakow Poland Institute of Zoology Poznan University of Life Sciences Poznan Poland

Interactions between ecological communities of herbivores and microbes are commonly mediated by a shared plant. A tripartite interaction between a pathogenic fungus-host plant-herbivorous insect is an example of such mutual influences. In such a system a fungal pathogen commonly has a negative influence on the morphology and biochemistry of the host plant, with consequences for insect herbivore performance. Here we studied whether the biotrophic fbngus Podosphaera ferruginea, attacking the great burnet Sanguisorba officinalis, affects caterpillar performance of the endangered scarce large blue butterfly Phengaris teleius. Our results showed that the pathogenic ftmgus affected the number and size of inflorescences produced by food-plants and, more importantly, had in direct, plant-mediated effects on the abun dance, body mass and immune response of caterpillars. Specifically, we found the relationship between caterpillar abundance and variability in inflorescence size on a plant to be positive among healthy food-plants, and negative among infected food-plants. Caterpillars that fed on healthy food-plants were smaller than those that fed on infected food-plants in one studied season, while there was no such difference in the other season. We observed the relationship between caterpillar immune response and the proportion of infected great burnets within a habitat patch to be positive when caterpillars fed on healthy food-plants, and negative when caterpillars fed on infected food-plants. Our results suggest that this biotrophic fungal infection of the great burnet may impose a significant indirect influence on P. teleius caterpillar performance with potential consequences for the population dynamics and structure of this endangered butterfly.

关键词： host plant insect herbivore Maculinea teleius Podosphaera ferruginea powdery mildew tripartite interactions

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Research on the Construction of a Novel Cyberspace Security Ecosystem

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Engineering 2018年第1期4卷 47-52页

作者： Xiao-Niu Yang Wei Wang Xiao-Feng Xu Guo-Rong Pang Chun-Lei Zhang Science and Technology on Communication Information Security Control Laboratory Jiaxing Zhejiang 314033 China Science and Technology on Electro-Optical Information Security Control Laboratory Tianfin 300300 China

Given the challenges facing the cyberspace of the nation, this paper presents the tripartite theory of cyberspace, based on the status quo of cyberspace. Corresponding strategies and a research architecture are proposed for common public networks （C space）, secure classified networks （S space）, and key infras- tructure networks （K space）, based on their individual characteristics. The features and security require- ments of these networks are then discussed. Taking C space as an example, we introduce the SMCRC （which stands for ＂situation awareness, monitoring and management, cooperative defense, response and recovery, and countermeasures and traceback＂） loop for constructing a cyberspace security ecosys- tem. Following a discussion on its characteristics and information exchange, our analysis focuses on the critical technologies of the SMCRC loop. To obtain more insight into national cyberspace security, special attention should be paid to global sensing and precise mapping, continuous detection and active manage- ment, cross-domain cooperation and systematic defense, autonomous response and rapid processing, and accurate traceback and countermeasure deterrence.

关键词： Cyberspace security ecosystem SMCRC loop tripartite theory of cyberspace

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Milestone of the meridian science──970th anniversary of the Chinese Bronze Statue of Meridian

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Chinese Science Bulletin 1998年第5期43卷 353-362页

作者： ZHANG Renji College of Life Sciences, Peking University, Beijing 100871, China College of Life Sciences Peking University Beijing 100871 China

For more than a thousand years, Chinese people were aware of the transmitted sensations by the application of needles on the body surface. This practice is called acupuncture. Acupuncture had been recorded and transcribed in writings and in drawings, until finally the acupoints were inscribed onto a bronze statue. The bronze statue was called the Meridian Figure. Deeply embodied in the bronze statue is a tripartite confrontation-prism representation of the humans body. This concept was a great scientific achievement in ancient China. The author traces the history of Meridian science described in traditional Chinese medical terms. Then he explores a clear analogy of the meridian pathway (MP) phenomenon. In a model system, by using a simple segmental in vertebrate, certain parallels can be demonstrated with the meridian concept. For example, the author demonstrated a clear correlation rule among the central mechano-sensory channels, and characteristics of positional discrimination in individual nerve cells from different receptive field inputs. The evidence suggests that the MP phenomenon is an objective neurobiological response. To clarify the research objective in this paper, the author suggests that the MP is a bi-directional pathway along which a positional message signal is transmitted. This phenomenon is evoked by physical stimulation, transmitted linearly across the human body segments, and is perceived by the brain. The MP consists of low resistance paths, is connected by the liquid media contained in the apposite membranous structure. At the cellular level, the regulation functions of MP must pass through along this low resistance path. Two aspects of the modern Meridian research are the functional regulation and the mechanism of intercellular liquid modulation at the nanometer level.

关键词： meridian pathway tripartite confrontation-prism coordinate position discriminative recognition apposite membranous structure.

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Microencapsulation of Banana Passion Fruit (<i>Passiflora tripartita Var. Mollissima</i>): A New Alternative as a Natural Additive as Antioxidant

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Food and Nutrition Sciences 2014年第8期5卷 671-682页

作者： Maritza Gil Ana Restrepo Leonidas Millán Luz Alzate Benjamín Rojano Chemestry Ecole National University of Colombia Medellin Colombia Engineering Faculty Lasalian University Corporation Caldas Colombia

Banana passion fruit (P. tripartita var. Mollissima) is one of the most promising tropical fruits giving its antioxidant activity (AOA) to replace synthetic additives. Despite this property, there are no studies about the metabolites responsible for its biological function or proposals for the application of technologies, such as microencapsulation by spray drying, to improve its properties and ease its incorporation in several food matrices. The aim of this study is to microencapsulate the pulp of banana passion fruit with several mixtures of encapsulants and identify which one of these mixtures is better to preserve its AOA. The antioxidant activity values for the banana passion fruit pulp were as follows: DPPH: 6630.2 ± 91 μMtrolox/100g;ABTS: 18764.3 ± 270.4 μMtrolox/100g;FRAP: 1703.6± 938.2 mgAA/100g, ORAC: 8105.4 ± 424.2 μmol TEAC/100g of sample;Total phenols: 8862.2 ± 451.4 gallic ac. mg/100g. The concentrations of the bioactive compounds expressed in mg of gallic acid per 100 g of the pulp on a dry base were 13.9 ± 0.004;5.9 ± 0.001 and 126.3 ± 0.004 for caffeic, p-coumaric and ferulic acids, respectively. The best shelf-life followed by ABTS in eight assays was between 28.8 and 31.5 weeks using maltodextrin and modified starch, MD:MS (1/4:3/4) and MD:MS (0:1), respectively. In conclusion, ABTS is the best method to measure the AOA in banana passion fruit because it correlated with the phenolic compounds better than DPPH and FRAP methods. Additionally, two options were found to protect the AOA and to extent the shelf-life of the passion fruit by spray-drying, with mixtures of encapsulants widely used in the food industry.

关键词： Passiflora tripartite ABTS Maltodextrin Microencapsulation Phenolic Compound

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Towards sustainable protection against insect-borne plant viral diseases:Phytohormones and beyond

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Science Foundation in China 2016年第2期24卷 69-80页

作者： WANG Ning YAO XiangMei ZHU ChangXiang WEN FuJiang YE Jian State Key Laboratory of Plant Genomics Institute of MicrobiologyChinese Academy of Sciences State Key Laboratory of Crop Biology Shandong Key Laboratory of Crop BiologyShandong Agricultural University

Due to the immobility of plants,around 75% of 1100 plant virus species are piercing-sucking insect *** plant-mediated interactions between viruses and insects play vital roles in the population dynamics of vectors and the epidemiology of plant diseases.A successful viral pathogen has to evolve multiple strategies to manipulate host immune responses and also the ecological environment to facilitate effective transmission by insect *** these strategies,reprogramming the phytohormone signaling pathways is critical to the establishment of an effective virus transmission among plants and disease ***,we review recent studies on the plant-virus inter-relationships with a focus on molecular and biochemical mechanisms that drive vector-borne viral ***-related phytohormones such as Jasmonic acid(JA),Salicylic acid(SA)and Ethylene(ET)have been reported to be directly regulated by viral *** knowledge is essential for the further design and/or development of effective and sustainable strategies to protect viral damages so as to increase crop yield and food *** efforts in this area should be focused on integrating and meta-analysis of big data generating from dynamics and multiple dimensional pathogen-vector-crop interactions under real agricultural conditions to achieve sustainable protection against plant diseases.

关键词： Phytohormone Jasmonic acid Virus-vector-plant tripartite interactions Geminivirus

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The Tragedy of Unbalanced Personality——The Common Personality Psychological Reasons of the Destruction of Emily and Usher

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海外英语 2014年第16期 223-224页

作者：胡星西北大学陕西西安710127

A Rose for Emily is the masterpiece of William Faulkner, who is regarded as the founder of Southern literature. The Fall of the House of Usher is one of the most popular short stories written by the great American writer Edgar Allan Poe. They have common ends that the main characters of the two novels—Emily and Usher are all destruction of their unbalanced *** thesis will set a new point from a branch view of psychology—personality psychology to analyze the two characters Emily and Usher, how they change from pathological personality to abnormal personality, and finally destruct from flesh to soul. The deep meaning is to announce the human inner world will distract by the outside world.

关键词： tripartite structural model unbalanced personality

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