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Effect of age on click-evoked otoacoustic emission A systematic review

Neural Regeneration Research 2012年第11期7卷 853-861页

作者： Jinfeng Liu Ningyu Wang Department of Otorhinolaryngology Head and Neck Surgery Beijing Chaoyang HospitalCapital Medical UniversityCollege of OtolaryngologyCapital Medical UniversityKey Laboratory of Otolaryngology Head and Neck SurgeryBeijing 100020China

OBJECTIVE：The aims of this study were to investigate the changes of the total intensity of transient evoked otoacoustic emission（TEOAE） and signal-to-noise ratio in various frequency bands as a function of aging,and to explore the role of age-related decline of cochlear outer hair *** SOURCES：The literature was searched using the PubMed database using ＇transient-evoked otoacoustic emissions＇ as a *** were limited as follows：Species was ＇Humans＇;languages were ＇English and Chinese＇;publication date between 1990-01-01 and *** references of the found were also searched to obtain additional *** SELECTION：Inclusion criteria：（1） Articles should involve the total TEOAE level or signal-to-noise ratio.（2） The measurement and analysis system used was Otodynamics ILO analysis system（ILO88,ILO92,ILO96 or ILO292）.（3） Studies involved groups of greater than 10 subjects and TEOAE results were from normally hearing ears.（4） If more papers from the same author or laboratory analyzed the same subjects,only one was *** OUTCOME MEASURES：The correlations of the age scale with the total level and signal-to-noise ratio of TEOAE was determined,***：（1） TEOAE total level gradually increased until 2 months of age,and then decreased with increasing *** negative correlations between total TEOAE level and age were found（r =-0.885,P = 0.000）.（2） The most rapid decrease of TEOAE amplitude occurred at 1 year *** total TEOAE level decreased about 4.25 dB SPL between 2 months to 1 year old,then about 0.26-0.52 dB SPL from 1 year to 10 years old,about 0.23 dB SPL from 11 years to 25 years old,and about 0.14 dB SPL from 26 years to 60 years old.（3） The signal-to-noise ratio in the frequency bands centered at 1.5,2,3 and 4 kHz decreased with increasing age after 2 months of *** negative correlations between the signal-to-noise ratio and age were found for frequency bands ranging from 1.5 kHz to 4 kHz,with the hig

关键词： age transient-evoked otoacoustic emission signal-to-noise ratio outer hair cells meta-analysis

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