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Granulocyte colony-stimulating factor-producing squamous cell carcinoma of the tongue exhibiting characteristic fluorine-18 deoxyglucose accumulation on positron emission tomography–computed tomography: A case report

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World Journal of Clinical Cases 2020年第9期8卷 1666-1673页

作者： Hiroaki Shimamoto Yuka Hirota Yoshihisa Kashima Naoya Kinoshita Misaki Yokokawa Tohru Ikeda Hiroyuki Harada Oral and Maxillofacial Surgery Graduate School of Medical and Dental SciencesTokyo Medical and Dental UniversityTokyo 113-8549Japan Human Pathology Graduate School of Medical and Dental SciencesTokyo Medical and Dental UniversityTokyo 113-8549Japan Oral Pathology Graduate School of Medical and Dental SciencesTokyo Medical and Dental UniversityTokyo 113-8549Japan

BACKGROUND Granulocyte colony-stimulating factor(G-CSF)is a cytokine produced in inflammatory environments that induces differentiation and proliferation of neutrophils in bone *** report a rare case of aggressive G-CSFproducing squamous cell carcinoma of the tongue exhibiting fluorine-18 deoxyglucose(FDG)accumulation in primary lesion,metastatic lymph nodes,spleen,and bone marrow on positron emission tomography–computed tomography(PET/CT).CASE SUMMARY We report a 58-year-old female with a rapid enlarged lingual mass with partial *** test results from the initial examination revealed a leukocyte count of 21380/μ*** PET/CT,extensive FDG accumulation was observed in the tongue and bilateral cervical lymph nodes,with elevated FDG accumulation in the spleen and bone marrow although no distant metastases were *** performed partial glossectomy and bilateral neck *** staining with G-CSF antibodies on biopsy specimen and resected samples revealed that both specimens were G-CSF *** is a rare case of G-CSF producing tongue carcinoma with elevated FDG accumulation in the spleen and bone *** In patients with the tongue cancer and hyperleukocytosis,where FDG accumulations in the spleen and bone marrow are observed using PET/CT and when these accumulations are not caused by metastasis,G-CSF-producing tumors,with associated poor prognosis,should be considered.

关键词： Tongue cancer Granulocyte colony-stimulating factor Hyperlukocytosis Positron emission tomograph Case report

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Effect of exercise on left and right ventricular ejection fraction and wallmotion in patients with coronary artery disease: an ultrafast computed tomography study

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Journal of Medical Colleges of PLA(China) 1998年第1期13卷 73-78页

作者：毛松寿王绍军

To measure the response of left and right ventricular ejection fraction and wall motion to exercise in eighteen patients with angiogl’aphically documented coronary artery disease (CAD) and in twenty-two patients with angiographicallynormal coronary arteries using ultrafast computed tomography(UFCT). Methods: Angiography and UFCT exercise cine studieswere performed for the evaluation of chest pain in all 40 cases, including 18 CAD patients and 22 patients with normal coronary arteries. Results: Of the 18 patients with CAD, 14(78% ) had a≥5% decrease in left ventricular ejection fraction (LVEF) duringexercise by UFCT (P 5%; none had an abnormal response in LV wall motion during peak exercise or a RVWMA at restor during stress. Using a decrease of ≥5 % in LVEF or a LVWMA or RVWMA during stress as a criterion for identifying patientswith CAD, the accuracy was 88% (35/40) with LVEF, 90% (36/40) with LVWMA, and 92% (37/40) with a combination ofLVEF, LVWMA and RVWMA. The sensitivity of RVWMA alone in detecting right coronary artery disease (RCAD) was 60%(6/10) and the specificity was 78% (7/9). Conclusion: Our study suggests that exercise-UFCT appears to be a useful tool for thedetection of CAD in patients with chest pain. The abnormal response of LVEF and exercise-induced LVWMA and RVWMA as determined by UFCT were important predictors CAD. Both LVWMA and RVWMA of important value in identifying patientswith CAN from those with normal coronary arteries, as is RVWMA in defining the existence of RCAD in patients with CAD.

关键词： ultrafast computed tomograph left ventricular ejection fraction right ventricular ejection fraction exercise test

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Role of the Reference Frame in Angular Photon Distribution at Electron-Positron Annihilation

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Journal of Modern Physics 2014年第6期5卷 353-358页

作者： Andrey N. Volobuev Eugene S. Petrov Eugene L. Ovchinnikov Department of Physics Samara State University Samara Russia

The reasons of angular photon distribution occurrence at electron-positron annihilation are considered. It is shown that angular photon distribution is consequence of Doppler’s effect in the reference frame of the electron and positron mass center. In the reference frame bound with moving electron the angular photon distribution is absent. But it is replaced by the Doppler’s shift of photons frequencies. The received results are applied to the analysis of a positron-emission tomograph work.

关键词： Annihilation Electron Positron Photon Doppler’s Effect Angular Photon Distribution Positron-Emission tomograph

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