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检索条件"主题词=thymidine"
40 条 记 录,以下是1-10 订阅
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thymidine kinase gene mutation leads to reduced virulence of pseudorabies virus
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Chinese Science Bulletin 2001年 第23期46卷 1972-1975页
作者: Pan, ZS Zhang, CY Ding, JH Min, P Wuhan Univ Coll Life Sci Inst Virol Wuhan 430072 Peoples R China
To explore correlation between the tk gene structure of pseudorabies virus (PRV) and its virulence, to study the effect of the gene mutation on PRV biological properties, and to investigate mechinism of reduced virule... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Induction of functional neutrophils from mouse fibroblasts by thymidine through enhancement of Tet3 activity
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Cellular & Molecular Immunology 2022年 第5期19卷 619-633页
作者: Buqing Ye Liuliu Yang Benyu Liu Nian Liu Dongdong Fan Huimu Li Lei Sun Ying Du Shuo Wang Yong Tian Zusen Fan Key Laboratory of Infection and Immunity of CAS Institute of BiophysicsChinese Academy of SciencesBeijing100101China Department of Biomedical Engineering College of Future TechnologyPeking UniversityBeijing100080China Research Center of Basic Medicine Academy of Medical SciencesZhengzhou UniversityZhengzhou450001China University of Chinese Academy of Sciences Beijing100049China Key Laboratory of RNA Biology Institute of BiophysicsChinese Academy of SciencesBeijing100101China Core Facility Center Institute of BiophysicsChinese Academy of SciencesBeijing100101China
Neutrophils are derived from bone marrow hematopoietic stem cells(HSCs)and are the largest population among circulating white blood cells in humans,acting as the first line of defense against invading *** neutrophils ... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
KPNI RESTRICTION SITE POLYMORPHISM IN HUMAN CYTOSOLIC thymidine KINASE GENE ON CHROMOSOME 17
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Chinese Science Bulletin 1989年 第18期34卷 1581-1582页
作者: 赵寿元 张钰 Institute of Genetics Fudan University Shanghai
The human cytosolic thymidine kinase (TK-C)gene has been localized on chromosome 17 (17q21--22). Morbid anatomy of the human genome has shown that seve?al disease genes are located in the same chromosome region. Our g... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Protective autophagy by thymidine causes resistance to rapamycin in colorectal cancer cells in vitro
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Cancer Drug Resistance 2021年 第3期4卷 719-727页
作者: I.V.Bijnsdorp Godefridus J.Peters Department of Medical Oncology Amsterdam UMClocation VUMC1007 MB AmsterdamNetherlands Department of Urology Amsterdam UMClocation VUMC1007 MB AmsterdamNetherlands Department of Biochemistry Medical University of Gdansk80-210 GdanskPoland
Aim:Thynidine phosphorylase(TP)acts as a proangiogenic growth factor which may regulate mammalian Target of Rapamycin(mTOR).We investigated whether the TP substrate thymidine and overexpression of TP affected mTOR sig... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
thymidine Glycol: The Effect on DNA Structure and DNA Binding by Site-Specific Proteins
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Natural Science 2015年 第11期7卷 491-509页
作者: Elena A. Kubareva Fan Yang Alexandra Yu. Ryazanova Nina G. Dolinnaya Andrei V. Golovin Nikolai V. Molochkov Elena A. Romanova Elizaveta A. Karpova Timofei S. Zatsepin Tatiana S. Oretskaya Belozersky Institute of Physico-Chemical Biology Lomonosov Moscow State University Moscow Russia Chemistry Department Lomonosov Moscow State University Moscow Russia Faculty of Bioengineering and Bioinformatics Lomonosov Moscow State University Moscow Russia Institute of Theoretical and Experimental Biophysics Russian Academy of Science Moscow Region Pushchino Russia
thymidine glycol (5,6-dihydroxy-5,6-dihydrothymidine, Tg) is a major type of oxidative damage in DNA. During chemical oligonucleotide synthesis, Tg residue was incorporated in the different positions of 17 b.p. DNA du... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
DFT-Based Chemical Reactivity Descriptors, Pharmacokinetics and Molecular Docking Studies of thymidine Derivatives
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Computational Chemistry 2023年 第4期11卷 81-103页
作者: Mohammad Ahad Hossain Shahin Sultana Mohammad Mazherul Islam Sonia Akhter Faria Nur Fatima Majabin Kantom Islam Kazi Jawad Hossain Yasuhiro Ozeki Sarkar M. A. Kawsar Laboratory of Carbohydrate and Nucleoside Chemistry (LCNC) Department of Chemistry Faculty of Science University of Chittagong Bangladesh Graduate School of NanoBio Sciences Yokohama City University Yokohama Japan
thymidine-containing derivatives are considered to be among the most significant derivatives in medicinal chemistry. In this study, we employed a combined computational approach involving density-functional theory (DF... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
急性白血病患者骨髓体外氚-胸腺嘧啶核苷(~3H-thymidine)掺入试验及其意义
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科学通报 1978年 第1期23卷 57-58页
细胞动力学的研究对于探索肿瘤的发展和指导肿瘤的化疗具有特殊重要的意义。近二十年来的研究,对于逐步阐明肿瘤细胞的普遍规律已作出了很大的贡献。但是对于临床病人,更需要了解个别病人、不同病期的特定的细胞动力学变化,并依据其特... 详细信息
来源: 同方期刊数据库 同方期刊数据库 评论
Chemical Composition of Hydrilla Verticillata (L. f.) Royle in Taihu Lake
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Chinese Journal of Chemistry 2007年 第5期25卷 661-665页
作者: 肖瑜 王艳丽 高士祥 孙成 周忠远 State Key Laboratory of Pollution Control and Resource Reuse School of the Environment Nanjing University Nanjing jiangsu 210093 China Department of Resource and Environmental Engineering Guilin University of Technology Guilin Guangxi 541004 China Department of Applied Biology and Chemical Technology Hong Kong Polytechnic University Hong Kong China
Hydrilla verticillata (Linn. f.) Royle is a submerged plant for phytoremediation on Taihu Lake, China. The planted submerged plant should be harvested in every autumn to reduce the nutrition burden of the lake. Five... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
METHODOLOGY FOR STUDIES OF CARBONDYNAMICS BETWEEN PHYTOPLANKTONPRIMARY PRODUCTION AND HETEROTROPHICBACTERIAL SECONDARY PRODUCTION
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Chinese Journal of Oceanology and Limnology 1989年 第1期7卷 17-32页
作者: 林婉莲 Jurgen Overbeck Institute of Hydrobiology Academia Sinica Wuhan Dept. of Microbial Ecology Max-Planck-Institute of Limnology F.R. Germany
The SCENTO-System was used to study the carbon dynamics between phytoplankton primary production and heterptrophic bacterial secondary production. Most of the methods used nowadays in situ for limnological synecology ... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
A POSSIBLE REGULATORY FACTOR(CALMODULIN) IN THE PROLIFERATION OF VASCULAR SMOOTH MUSCLE CELLS
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Chinese Science Bulletin 1989年 第2期34卷 174-175页
作者: 卢坤平 赵昇皓 王道生 Department of Biochemistry Xuzhou Medical College Department of Pharmacology Suzhou Medical College
The proliferation of vascular smooth muscle cells accompanies the pathogenesis of atherosclerosis and hypertension. It is known that Ca2+ion controls the proliferation of several lines of cells. However, whether Ca2+ ... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论