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《thoracic cancer》被SCI收录

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中国肺癌杂志 2012年第11期 623-623页

2011年6月25日,天津肺癌研究所收到美国Thomson-Reuters公司通知,天津肺癌研究所与Wiley-Blackwell合办的oraciccancer自创刊号起所有文章被SCI收录。

关键词： SCI thoracic cancer 胸部肿瘤

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Radiotherapy-induced heart disease:a review of the literature

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Precision Clinical Medicine 2019年第4期2卷 270-282页

作者： Bingwen Zou Julius Philipp Schuster Kerun Niu Qianyi Huang Alexander Rühle Peter Ernst Huber Department of Radiation Oncology Heidelberg University HospitalIm Neuenheimer Feld 400Heidelberg 69120Germany Department of Molecular Radiation Oncology German Cancer Research CenterIm Neuenheimer Feld 280Heidelberg 69120Germany Heidelberg Institute for Radiation Oncology(HIRO)and National Center for Radiation Oncology(NCRO) Im Neuenheimer Feld 280Heidelberg 69120Germany

Radiotherapy as one of the four pillars of cancer therapy plays a critical role in the multimodal treatment of thoracic *** to significant improvements in overall cancer survival,radiotherapy-induced heart disease(RIHD)has become an increasingly recognized adverse reaction which contributes to major radiationassociated toxicities including non-malignant *** is especially relevant for patients suffering from diseases with excellent prognosis such as breast cancer or Hodgkin’s lymphoma,since RIHD may occur decades after *** studies have enriched our knowledge of many potential mechanisms by which thoracic radiotherapy induces heart *** findings in humans reveal that irradiation might increase the risk of cardiac disease at even lower doses than previously *** preclinical studies have identified non-invasive methods for evaluation of ***,potential options preventing or at least attenuating RIHD have been *** research may enrich our limited knowledge about biological mechanisms of RIHD,identify non-invasive early detection biomarkers and investigate potential treatment options that might attenuate or prevent these unwanted side ***,we present a comprehensive review about the published literature regarding clinical manifestation and pathological alterations in *** mechanisms and treatment options are outlined,and challenges in RIHD treatment are summarized.

关键词： Radiotherapy heart injury thoracic cancer radiation-induced heart injury cancer treatment

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Lung cancer management during the COVID-19 pandemic:experience of a medical oncology unit at a tertiary hospital in Singapore

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Journal of cancer Metastasis and Treatment 2020年第1期6卷 707-717页

作者： Elise KY Vong Puey-Ling Chia Alex Y.Chang Department of Medical Oncology Tan Tock Seng HospitalSingapore Lee Kong Chian School of Medicine Singapore Johns Hopkins University School of Medicine BaltimoreMD 21836USA

Coronavirus disease 2019(COVID-19),caused by the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),was declared a pandemic by the World Health Organisation(WHO)on 11 March *** pandemic has had profound effects on healthcare systems across the world,and also poses unique challenges for oncology *** saw its first imported case of COVID-19 on 23 January 2020,and there has since been 52,000 confirmed cases and 27 deaths as of early August 2020 *** have a special duty to our patients to ensure patient safety and provide optimum care without undue disruption which may compromise long-term cancer-specific *** herein examine the impact that the COVID-19 pandemic has had on our clinical services,and share our experience with regards to manpower reconfiguration,infection control measures,diagnostic evaluation of patients with suspected COVID-19,oncological management of lung cancer patients,as well as changes in the education and training of juniors,from our unique position as a Medical Oncology department in Tan Tock Seng Hospital,a tertiary hospital affiliated with the National Centre of Infectious Diseases in Singapore.

关键词： COVID-19 lung cancer thoracic cancer

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Dose Calculation Accuracy of Individualized Bulk Electron Density Assignment Approaches for Simulated MRI-only Planning of thoracic Tumors

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Chinese Journal of Biomedical Engineering(English Edition) 2020年第3期29卷 40-46页

作者： Shuxu Zhang Qingxing Zeng Yuliang Liao Shengqu Lin Guoquan Zhang Huaiyu Lei Ruihao Wang Hui Yu Quanbin Zhang Ping Li Radiotherapy Center Affiliated Cancer Hospital&Institute of Guangzhou Medical UniversityGuangzhou Guangdong 510095China

Objective This study aimed to investigate the dose calculation accuracy of individualized bulk electron density(IBED)assignment approaches for simulated magnetic resonance imaging(MRI)-only planning of thoracic tumors via the use of a 3 DVH *** 8 patients with thoracic cancer were included in this *** on standard planning CT,single-arc dynamic conformal therapy(DCT)and double-arc volumetric modulated arc therapy(VMAT)plans with a6 MV photon beam were generated as a baseline plan(Plan-CT)for each *** simulated MRI-only planning(Plan-IBED)was implemented by copying the Plan-CT and forcing the electron density of each region of interest to its average value and recalculating the dose distribution.A 3 DVH system was used to visualize and compare the dosimetric differences between Plan-CT and Plan-IBED,and the criteria of the 3 D-Gamma pass rate were set to 1.0%/1.0 *** The maximum percentage relative deviation(MPRD)of the dosimetric parameters D2,D95,D98,and Dmean of planning tumor volumes(PTVs)between Plan-CT and Plan-IBED was less than 1.3%.The MPRD of the average dose for organs at risk(OARs)was less than 1.5%.The MPRDs of the lung V5,V20,and V30 were 1.29%,3.26%,and 2.78%,*** analysis revealed an averaged pass rate of>95.0%for the body,as well as between 91.9%and 98.2%for *** The proposed IBED assignment in simulated MRI-only treatment planning allows for dose calculation with comparable accuracy to the baseline plan and is appropriate for thoracic tumors.

关键词： Individualized bulk electron density(IBED) Relative electron density(RED) thoracic cancer 3DVH software MRI-only planning

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