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Psychosomatic Medicine Research 2022年第1期4卷 1-7页

作者： Qi Zhang Tianjin university of traditional Chinese medicine TianjinChina

Objective:To investigate the current status of kinesiophobia in patients with temporomandibular disorders(TMD)and analyze its risk factors.Methods:The Tampa Scale for kinesiophobia for patients with temporomandibular disorders(TSK-TMD),Numerical Rating Scale(NRS),Hospital Anxiety and Depression Scale(HADS),General Self-Efficacy Scale(GSES),Simplified Coping Style Questionnaire(SCSQ),and Social Support Rating Scale(SSRS)were adopted to measure patient's kinesiophobia,pain intensity,anxiety,depression,self-efficacy,coping styles and social support.Multiple linear regression was used to analyze the risk factors of kinesiophobia in patients with TMD.Results:A total of 307 participants were included in the present study.The average score of patients with kinesiophobia was(34.37±6.96)points.Multiple linear regression analysis showed that pain duration,worst pain intensity,mouth opening limitation,joint noise,joint trauma,self-efficacy,depression,negative coping style,support utilization and education level are independent risk factors for kinesiophobia.Conclusion:Patients with TMD have higher levels of kinesiophobia and poor recognition of the disease.Longer pain duration,pain intensity,mouth opening limitation,joint noise,joint trauma,lower self-efficacy,depression,negative coping style,lower support utilization and lower educational level can be used to predict the degree of kinesiophobia.

关键词： Kinesiophobia Risk factors Cross-sectional study temporomandibular disorders

Relationship between uncertainty in illness,mood state and coping style in patients with temporomandibular disorders

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International Journal of Nursing Sciences 2015年第4期2卷 361-365页

作者： Dong-ye Yang Jing-jing Ye Feng Zhou Jue-jun Li Qiu-yu Huang Li-hong Wan Guanghua School of Stomatology Hospital of StomatologySun Yat-sen UniversityGuangzhouChina Center for ADR monitoring of Chengdu SichuanChina School of Nursing Sun Yat-sen UniversityGuangzhouChina

Objective:To investigate the relationship between uncertainty in illness,mood state and coping style in patients with temporomandibular disorders(TMD)in the hospital,in order to identify nursing measures.Methods:Chinese versions of the Mishel Uncertainty In Illness Scale(MUIS),Brief Profile Of Mood States(BPOMS)and Medical Coping Modes Questionnaire(MCMQ)were used to assess uncertainty in illness,mood state and coping style,respectively,in 126 patients with TMD.Results:The total score of uncertainty in illness of the patients was 91.33±16.38,which was at middle level.The total score of mood state was 37.93±17.0.The order of coping style rated from high to low was confrontation(18.81±3.65),avoidance(15.44±4.26)and acceptance(10.41±5.04).Acceptance was positively correlated with uncertainty in illness(r=0.463,p<0.001),and mood state(r=0.187,p<0.05).Avoidance and confrontation were negatively correlated with uncertainty in illness and mood state(r=0.286,p<0.01),(r=0.175,p<0.05),(r=0.171,p<0.05),(r=0.221,p<0.01).Conclusions:Both uncertainty in illness and mood state were related to coping style.These data suggest that nurses should be trained to offer appropriate guidance to help decrease patients'uncertainty in illness and relieve their negative emotions.

关键词： Coping style Mood state temporomandibular disorders Uncertainty in illness

Effect of Articular Cavity Injection Combined with Bite Splint Treatment on Anterior Disc Displacement Without Reduction

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Journal of Clinical and Nursing Research 2024年第1期8卷 133-139页

作者： Mengran Zhu Linghong Xu Suzhou Huaxia Stomatological Hospital Suzhou 215000Jiangsu ProvinceChina

Objective:To observe the clinical effect of articular cavity injection combined with bite splint therapy for the treatment of anterior disc displacement without reduction(ADDWoR).Methods:The research subjects for this study were 30 patients with ADDWoR treated in the temporomandibular joint specialist outpatient clinic from November 2018 to November 2019,with a disease duration of 1 to 6 months.The treatment group was treated with an articular cavity injection of sodium hyaluronate+bite splint.The control group was treated with a simple articular cavity injection of sodium hyaluronate.The two groups were followed up once every 2 weeks to evaluate the treatment effect and observe the clinical efficacy of the two groups.Statistical analysis was carried out using SPSS 24.0.t-test and general linear regression analysis were carried out to compare the data of both groups,andχ^(2)-test and binary logistic regression analysis were performed for pain index comparison.Results:There was no significant difference in terms of the efficacy of the treatment received by both groups.The mouth opening and joint pain of patients in both groups were significantly improved after treatment(P<0.001).Conclusion:Articular cavity injection of sodium hyaluronate and occlusal splint therapy are both effective and safe methods for treating ADDWoR.

关键词： temporomandibular disorders Anterior disc displacement without reduction Sodium hyaluronate Splint

Screening Survey of Pain Intensity in Patients with temporomandibular disorders

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Open Journal of Stomatology 2021年第6期11卷 231-243页

作者： Takashi Uchida Takashi Iida Masanobu Wakami Osamu Komiyama Kayo Kuyama Orofacial and Head Pain Clinic Nihon University Hospital at Matsudo Chiba Japan Deparoment of Oral Diagnostics Nihon University School of Dentistry at Matsudo Chiba Japan Department of Oral Function and Fixed Prosthodontics Nihon University School of Dentistry at Matsudo Chiba Japan Department of Pathology Nihon University School of Dentistry at Matsudo Chiba Japan

Objective: Pain tends to be the chief complaint in patients suffering temporomandibular disorders (TMD). Previous studies on pain and psychosocial factors have reported on the relationship between presence of pain and mental disorders. To date, however, few studies have addressed the relationship between intensity of pain and psychosocial factors. In this study, we investigated the relationship between intensity of pain and age, gender, palpation scores (PPS), tendencies toward depression, anxiety, and somatization, and oral parafunctional habits. Methods: This screening survey encompassed 104 patients (70 women and 34 men;mean age of 46.1 ± 19.3) who visited our clinic. We gathered the following data: age;gender;PPS included in Axis I diagnosis;and characteristic pain intensity (CPI), depression, anxiety, somatization, and oral parafunctional habits (assessed by the Oral Behavior Checklist) included in Axis II diagnosis. Based on the results of CPI, we divided patients into two groups: those experiencing low pain intensity (LP group) and those experiencing high pain intensity (HP group). The statistically significant level was set to below 5%. IBM SPSS Statistics V25 was used to perform all statistical analyses. Results: We observed no gender differences between LP and HP groups. The HP group included significantly more patients with higher scores for depression, anxiety, somatization, and oral parafunctional habits than the LP group. While no gender differences were observed in CPI, depression, anxiety, somatization, and oral parafunctional habits were significantly more common in women than in men. We observed no differences in age or PPS between the LP and HP groups. However, scores for depression, anxiety, somatization, and oral parafunctional habits were significantly higher in the HP group than in the LP group. We performed multiple regression analysis using the CPI score as the dependent variable and scores for depression, anxiety, somatization, and oral

关键词： temporomandibular disorders DC/TMD Psychosocial Assessment Depression

Research progress of Kinesiophbia in patients with temporomandibular disorders

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TMR Integrative Nursing 2020年第1期4卷 1-8页

作者： Qi Zhang Wen-Jing Ran Xue Feng Li-Rong Nie Ying-Shu Jin Juan Zhang Graduate College Tianjin University of Traditional Chinese Medicine301617China Infections department Tianjin Medical University Stomatological Hospital300070China Department of Prosthodontics Tianjin Medical University Stomatological Hospital300070China.

This article reviews the source and concept of Kinesiophbia,the assessment tools,the adverse effects on temporomandibular disorders,the influencing factors and intervention methods,and provides a reference for clinical practitioners to choose appropriate intervention regimes.Nursing staff provide information support for effective health education,thereby reducing the level of patients with Kinesiophbia,promoting the recovery of mandibular function and improving their quality of life.

关键词： temporomandibular disorders Kinesiophbia Review

Cerebral activation during unilateral clenching in patients with temporomandibular joint synovitis and biting pain： an functional magnetic resonance imaging study

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Chinese Medical Journal 2011年第14期124卷 2136-2143页

作者： ZHAO Yan-ping MA Xu-chen, JIN Zhen LI Ke LIU Gang ZENG Ya-wei Department of Oral Radiology and Center for temporomandibular disorders Peking University School and Hospital of StomatologyBeijing 100081 China Department of Radiology 306 Hospital of People's Liberation Army Beijing 100101 China

Background Functional magnetic resonance is a non-invasive method that can examine brain activity and has been widely used in various fields including jaw movement and pain processing. temporomandibular disorder （TMD） is one of the most frequent facial pain problems. The objective of this study was to investigate the brain activities using functional magnetic resonance imaging （fMRI） during unilateral maximal voluntary clenching tasks in the TMD synovitis patients with biting pain.Methods Fourteen TMD synovitis patients with unilateral biting pain and 14 controls were included in the study.Contralateral biting pain was defined as right molar clenching causing left temporomandibular joint （TMJ） pain. Ipsilateral biting pain was defined as right molar clenching causing right TMJ pain. Symptom Check List-90 （SCL-90） was administered to the patients and controls. Independent sample t-test was used to compare the SCL-90 subscales between the two groups. Unilateral clenching tasks were performed by the patients and controls. Imaging data were analyzed using SPM99.Results Patients were divided into contralateral TMD biting pain group （n=8） and ipsilateral TMD biting pain group （n=6）. The SCL-90 subscales were significantly different between the two groups for somatization, depression, anxiety,phobic anxiety, and paranoid ideation. Group analysis of the controls demonstrated brain activations in the inferior frontal gyrus, precentral gyrus, middle frontal gyrus, superior temporal gyrus, and insular. The areas of activation were different between right and left clenching task. In TMJ synovitis patients with contralateral or ipsilateral biting pain, the group analysis showed activations in the inferior frontal gyrus, superior temporal gyrus, medium frontal gyrus, precentral gyrus,and anterior cingulate cortex.Conclusions The inferior frontal gyrus and precentral gyrus play essential roles during the unilateral clenching task.Activation of anterior cingulate cortex in the synovitis patients with biting pain was associated w

关键词： functional magnetic resonance imaging unilateral clenching task inferior frontal gyrus precentral gyrus temporomandibular disorders synovitis

Mutual Effect between Neuropeptides and Inflammatory Cytokines in Neurogenic SMSCs of Human temporomandibular Joint

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Journal of Huazhong University of Science and Technology(Medical Sciences) 2014年第4期34卷 602-607页

作者：刘志明彭友俭龙星李健柯金房维 Renmin Hospital of Wuhan University Key Laboratory of Oral Biomedicine Ministry of Education School & Hospital of Stomatology Wuhan University Department of Oral and Maxillofacial Surgery Hospital of Stomatology Wuhan University

In temporomandibular disorders（TMD）, pain takes place when neuropeptides stimulate synovial tissue to produce several cytokines such as interleukin（IL）-1β, IL-6 and tumor necrosis factor（TNF）-α, which activate neurons and glia of synovial membrane at the bilaminar regions of temporomandibular joint（TMJ）. It has been reported that, after neurogenic differentiation, the synovial mesenchymal stem cells（SMSCs）, deriving from TMJ, possess the same cytological features as the neuronal cells. This study examined the ability of substance P（SP） and calcitonin gene-related peptide（CGRP） to stimulate SMSCs and neurogenic SMSCs secreting inflammatory cytokines during TMD, evaluated the mutual effects of inflammatory cytokines and neuropeptides and tested the analgesic effect of hyaluronic acid（HA）. The levels of IL-1β, IL-6 and TNF-α in SMSCs and neurogenic SMSCs in the presence of neuropeptides were measured by ELISA. SP and CGRP produced by SMSCs and neurogenic SMSCs were determined by RT-PCR and Western blotting. The results showed that the expression of SP and CGRP was significantly enhanced in the neurogenic SMSCs in response to IL-1β, IL-6 and TNF-α, and the effect was remarkably inhibited by HA. IL-1β, IL-6 and TNF-α, in return, could be enhanced in the neurogenic SMSCs upon stimulation by SP and CGRP. Neuropeptides and inflammatory cytokines might work mutually on the TMD pain. The HA-mediated analgesic effect may be implicated in the inhibition of SP and CGRP expression in neurogenic SMSCs.

关键词： hyaluronic acid inflammatory cytokines substance P calcitonin gene-related peptide neurogenesis temporomandibular disorders

Validation of a Chinese version of the RDC/TMD axisⅡquestionnaire

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Validation of a Chinese version of the RDC/TMD axisⅡquestio...

Condylar remodeling accompanying splint therapy

中华口腔医学会第14次全国口腔医学学术会议（2012年...

作者： CHEN Weisheng,ZHENG Youhua,WU Xiayi,LIN Xuefeng Guanghua School of Stomatology,Hospital of Stomatology,Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology,Guangzhou 510055,China

Objective The aim of this study is cross-cultural adaptation of the Research Diagnostic Criteria for temporomandibular disorders(RDC/TMD) axisⅡquestionnaire, establish a Chinese version of the RDC/TMD axisⅡquestionn... 详细信息

关键词： temporomandibular disorders Research Diagnostic Criteria for temporomandibular disorders cross-cultural adaptation reliability validity

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Condylar remodeling accompanying splint therapy