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Patterns of Relapse and Management Options in Unknown Primary Cervical Metastatic Carcinoma

The Chinese-German Journal of Clinical Oncology 2005年第3期4卷 132-136,187页

作者：彭汉伟郭朱明曾宗渊陈福进李浩魏茂文伍国号张诠杨安奎广州中山大学肿瘤防治中心头颈科 510060

Objective: To analyze the patterns of relapse and management options in unknown primary cervical metastatic carcinoma (UPCMC) as well as to discuss its treatment strategies. Methods: Clinical data of 111 cases of eligible UPCMC were retrospectively studied. Neck control, primary relapse and long-term survival were compared among different groups. Results: Primary carcinomas ultimately appeared in 12 cases (10.8%, 12/111). Neck control rate was 36.9%. Overall 5-year survival rate was 41.4%. Neck control, N stage and primary control were prognostic factors for UPCMC. Neck control was affected by N stage and whether or not comprehensive radiotherapy was administered. Conclusion: UPCMC should primarily be treated by radiotherapy except for cases with N1 or N2 insensitive to radiation. Bilateral necks radiotherapy is the optimal choice in terms of neck radiotherapy. Selective total pharyngeal irradiation is recommended for potential primary treatment.

关键词： cervical metastasis, unknown primary radiotherapy surgery synthetic therapy

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The potential function of transhiatal esophagectomy in the treatment of esophageal carcinoma

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The Chinese-German Journal of Clinical Oncology 2008年第1期7卷 31-34页

作者： Xiufeng Cao Jian Xiao Shan Wang Bichao Wu Zhihua Huang Shuiqing Huang Heming Wang Yisheng Li Bin Zhu The Third Clinical Teaching Hospital of Nanjing Medical University Nanjing 210006 China Chest Surgery of Cancer Hospital in Yancheng City Yancheng 224002 China

Objective： To analyze the results and introduce the experiences of transhiatal esophagectomy in combined with different synthetic therapy. Methods： Seventy-one patients with esophageal carcinoma, median age was 62, 40 of stage Ⅰ, 26 of Ⅱa, 4 of stage Ⅱb, 1 of stage Ⅳ, were treated with transhiatal esophagectomy. 9 and 17 patients were treated with preoperative radiotherapy （4000 cGy） and postoperative adjuvant radiotherapy （6000 cGy） respectively; 5 patients were treated with preoperative chemotherapy. Results： The postoperative 1, 3 and 5 years survival rates were 100%, 91.43%, and 86.21% for stage Ⅰ; 92%, 83.33%, and 57.14% for stage Ⅱa; 75%, 50%, and 50% for stage Ⅱb; 100%, 0, and 0 for stag Ⅳ and 95.71%, 86.89%, and 71.70% as a whole, respectively. The incidence of complications was 12.68%. Conclusion： Transhiatal esophagectomy combined with chemotherapy or radiotherapy may be beneficial to patients with esophageal carcinoma at stage Ⅱa or earlier who can＇t tolerate or need not be treated by transthoracic esophagectomy.

关键词： esophageal carcinoma transhiatal esophagectomy synthetic therapy

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