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Burn injury differentially alters whole-blood and organ glutathione synthesis rates: An experimental model

Burns & Trauma 2013年第2期1卷 87-94页

作者： Zhe-Wei Fei Vernon R. Young Xiao-Ming Lu Andrew B. Rhodes Ronald G.Tompkins Alan J. Fischman Yong-Ming Yu Shriners Burns Hospital and Burn & Trauma Service Massachusetts General Hospital Harvard Medical School Boston MA 02114 Shriners Burns Hospital and Burn & Trauma Service Massachusetts General Hospital Harvard Medical School Boston MA 02114 Laboratory of Human Nutrition Massachusetts Institute of Technology Cambridge MA 02142 USA

Previous studies from our laboratories revealed a reduced rate of whole-blood (WB) glutathione (GSH) synthesis in severely burned patients. To determine whether WB GSH metabolism is an indicator of the status of GSH metabolism in one or more of the major organs, we used a burn rabbit model to determine GSH concentrations and rates of synthesis in WB, liver, lungs, kidney, and skeletal muscle. L-[1-13C]-cysteine was infused intravenously for 6 h in rabbits at 3 days post-burn and in sham burn controls. WB and organ 13C-enrichment of cysteine and GSH was determined by gas chromatography/mass spectrometry. Plasma cysteine metabolic flux was increased significantly (P rates of GSH synthesis (P rate of GSH transport out of the liver after burn injury. Hence, there is a differential impact of burn injury on tissue and organ GSH status, with WB qualitatively reflecting the changes in lung and liver. It will be important to determine whether these changes are due to alterations in the intrinsic capacity for GSH synthesis and/or availability of amino acid precursors of GSH.

关键词： Burn injury glutathione glutathione concentration synthesis rate whole blood

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Preparation of BaAl_2O_4 by microwave sintering

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Transactions of Nonferrous Metals Society of China 2010年第10期20卷 2020-2025页

作者：张念炳白晨光马莽原黎志英 College of Materials Science and Engineering Chongqing University College of Material and Civil Engineering Guizhou Normal University College of Materials and Metallurgy Guizhou University

The desulfurater(BaAl2O4) was successfully synthesized with BaCO3 and Al(OH)3 powders as raw materials by microwave sintering *** mass loss of raw materials and the characterization of the outcome were investigated by means of TG-DSC,XRD and optical *** reaction mechanism was *** experimental results show that synthesized BaAl2O4 by microwave sintering method is *** with conventional sintering method,microwave sintering is a better way to synthesize BaAl2O4 with advantages of low temperature sintering,short time sintering and high synthesis rate.

关键词： BaAl2O4, microwave sintering conventional sintering synthesis rate

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