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Wearable sweat biosensors on textiles for health monitoring

Journal of Semiconductors 2023年第2期44卷 11-24页

作者： Yuqing Shi Ziyu Zhang Qiyao Huang Yuanjing Lin Zijian Zheng School of Microelectronics Southern University of Science and TechnologyShenzhen 518055China School of Fashion&Textiles The Hong Kong Polytechnic UniversityHong Kong SARChina Department of Applied Biology and Chemical Technology The Hong Kong Polytechnic UniversityHong Kong SARChina Research Institute for Intelligent Wearable Systems(RI-Wear) The Hong Kong Polytechnic UniversityHong Kong SARChina

With the rapid technological innovation in materials engineering and device integration,a wide variety of textilebased wearable biosensors have emerged as promising platforms for personalized healthcare,exercise monitoring,and pre-diagnostics.This paper reviews the recent progress in sweat biosensors and sensing systems integrated into textiles for wearable body status monitoring.The mechanisms of biosensors that are commonly adopted for biomarkers analysis are first introduced.The classification,fabrication methods,and applications of textile conductors in different configurations and dimensions are then summarized.Afterward,innovative strategies to achieve efficient sweat collection with textile-based sensing patches are presented,followed by an in-depth discussion on nanoengineering and system integration approaches for the enhancement of sensing performance.Finally,the challenges of textile-based sweat sensing devices associated with the device reusability,washability,stability,and fabrication reproducibility are discussed from the perspective of their practical applications in wearable healthcare.

关键词： biosensor textile-based electronics wearable device sweat analysis health monitoring

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Facile and Low-Cost Fabrication of a Thread/Paper-Based Wearable System for Simultaneous Detection of Lactate and pH in Human sweat

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Advanced Fiber Materials 2020年第5期2卷 265-278页

作者： Gang Xiao Jing He Yan Qiao Feng Wang Qingyou Xia Xin Wang Ling Yu Zhisong Lu Chang-Ming Li Institute for Clean Energy and Advanced Materials School of Materials and EnergySouthwest University1 Tiansheng RoadChongqing 400715People’s Republic of China State Key Laboratory of Silkworm Genome Biology Southwest University1 Tiansheng RoadChongqing 400715People’s Republic of China Chongqing Engineering and Technology Research Center for Novel Silk Materials Southwest University1 Tiansheng RoadChongqing 400715People’s Republic of China College of Food Science Southwest UniversityNo.2 Tiansheng RoadBeibei DistrictChongqing 400715People’s Republic of China Institute of Advanced Cross-Field Science Qingdao UniversityQingdao 266071People’s Republic of China

Wearable devices have received tremendous interests in human sweat analysis in the past few years.However,the widely used polymeric substrates and the layer-by-layer stacking structures greatly influence the cost-efficiency,conformability and breathability of the devices,further hindering their practical applications.Herein,we report a facile and low-cost strategy for the fabrication of a skin-friendly thread/paper-based wearable system consisting of a sweat reservoir and a multi-sensing component for simultaneous in situ analysis of sweat pH and lactate.In the system,hydrophilic silk thread serves as the micro-channel to guide the liquid flow.Filter papers were functionalized to prepare colorimetric sensors for lactate and pH.The smartphone-based quantitative analysis shows that the sensors are sensitive and reliable.Although pH may interfere the lactate detection,the pH detected simultaneously could be employed to correct the measured data for the achievement of a precise lactate level.After being integrated with a hydrophobic arm guard,the system was successfully used for the on-body measurement of pH and lactate in the sweats secreted from the volunteers.This low-cost,easy-to-fabricate,light-weight and flexible thread/paper-based microfluidic sensing device may hold great potentials as a wearable system in human sweat analysis and point-of-care diagnostics.

关键词： Wearable sensors Thread/paper-based microfluidics sweat analysis Point-of-care diagnostics Multi-sensing system

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