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Magnetic Resonance Imaging of Atherosclerotic Lesion with New Devised Animal surface coil

Journal of Shanghai Jiaotong university(Science) 2008年第6期13卷 748-752页

作者：赵炳辉李明华赵清程英升肖云峰赵家民 Radiology Department Shanghai 6th People's HospitalShanghai Jiaotong UniversityShanghai 200233China Cardiology Department Shanghai 6th People's Hospital Shanghai Jiaotong UniversityShanghai 200233China Shanghai Chenguang Medical Technology Company Shanghai 200233China

The ability of dynamic contrast enhanced magnetic resonance imaging(DCE MRI) with a new devised animal surface coil was analyzed in identifying atherosclerotic plaques in the rabbit medium-sized iliac artery(IA).Then a comparative analysis of multi-detector computed tomography(MDCT) and DCE MRI was done in discerning morphology and components of 80 atherosclerotic plaques identified by *** shows that the DCE MRI may be an emerging noninvasive and economic way to characterize atherosclerotic plaques at ***'s more, a new devised animal surface coil would further improve the signal-to-noise ratio(SNR) and the quality of ***, CT angiography(CTA) may be better than MR angiography(MRA) in detecting vessel stenosis.

关键词： surface coil magnetic resonance imaging multi-detector CT atherosclerotic plaque

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In vivo Dynamic Studies of Brain Metabolism

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Tsinghua Science and Technology 2005年第4期10卷 496-498页

作者：罗雪春蒋玉凤张日清 Department of Biological Sciences and Biotechnology Tsinghua University Beijing 100084 China State Key Laboratory of Biomembrane and Membrane Biotechnology Tsinghua University Beijing 100084 China Department of Pathology Beijing University of Chinese Medicine Beijing 100029 China

Nuclear magnetic resonance （NMR） can noninvasively monitor intracellular concentrations and kinetic properties of numerous inorganic and organic compounds. A ^31p NMR surface coil was used in vivo to dynamically measure phosphocreatine （PCr）, adenosine triphosphate （ATP）, and intracellular inorganic phosphate （Pi） levels in mouse brain during ischemia-reperfusion to study the damage of cerebral tissues caused by ischemia and effects of herbs on cerebral energy metabolism during ischemia-reperfusion. The study provides dynamic brain energy metabolism data during different periods. The data show that some herbs more rapidly increase the PCr level during the recovery phase than in the control group.

关键词： nuclear magnetic resonance (NMR) surface coil ischemia-reperfusion herbs

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In Vivo Study of Brain Metabolism Using Nuclear Magnetic Resonance

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Tsinghua Science and Technology 1998年第3期3卷 62-64页

作者：罗雪春赵南明张日清李克玲蒋玉凤黄启福

Information on brain metabolism is very important, especially concerning the sequence of hypoxic ischemic episodes. Ultrasound, magnetic resonance image (MRI) and computer aided topography (CAT) allow visualization of changes due to hemorrhages. However, these methods do not detect the biochemical effects due to hypoxia and ischemia. This paper presents in vivo observations of brain metabolism attested by hypoxide and ischemia made using magnetic resonance spectroscopy(MRS), a noninvasive and nondestructive method which can identify the chemical compounds and monitor their changes during the biochemical reaction process for in vivo dynamic observation. 

关键词： brain metabolism NMR surface coil

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