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A Randomized Trial to Assess the Long-term safety of neuroaid among Caucasian Patients with Acute Ischemic stroke

Chinese Journal of Integrative Medicine 2014年第11期20卷 812-817页

作者： Reza Bavarsad shahripour Ahmad Hemati Ana Hosseinzadeh maleki Department of Neurology Ahvaz University of Medical Sciences Comprehensive stroke Center Department of NeurologyUniversity of Alabama at Birmingham

Objective：To assess the long-term（up to 6 months）safety profile of a 3-month regimen of neuroaid for acute ischemic ***：A total of 190 patients with acute ischemic stroke were identified for eligibility in a randomized,double-blind,placebo-controlled clinical trial,of which 150 patients allocated to either receiving neuroaid（80 cases）or placebo（70 cases）were analyzed after dropouts due to absence of baseline data,early death,or *** groups received treatment for three months and followed up for another three months after the completion of the *** of clinical adverse events and laboratory parameters were assessed at 1 month,3 months（while under treatment）and 6 months（3 months after the completion of treatment）.Statistical comparisons between groups were performed using chi-square test or t-test whenever ***：The two groups had comparable baseline *** nausea was more commonly reported in patients taking neuroaid compared with placebo（P=0.01）,of which 9 out of10 were observed only during the first month of ***,none of the adverse events reported were considered severe or required discontinuation of the study *** was no significant change observed in mean arterial blood pressure,haemoglobin,renal and liver laboratory parameters during treatment with neuroaid and up to 3 months after completion of a 3-month ***：neuroaid is safe and does not affect hematologic,hepatic,and renal functions during and long after completion of treatment.

关键词： stroke neuroaid safety

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