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Inactivation of the bed nucleus of the stria terminalis suppresses the innate fear responses of rats induced by the odor of cat urine

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畜牧与兽医 2012年第S1期44卷 376-376页

作者： Hai-Yang Xu Ying-Juan Liu Ming-Yuan Xu Jin-Hua Zhang Jian-Xu Zhang Yi-Jun Wu Laboratory of Molecular Toxicology Institute of Zoology Chinese Academy of Sciences Group for Animal Behavior and Chemical Communication State Key Laboratory of Integrated Management of Pest Insects and RodentsInstitute of Zoology Chinese Academy of Sciences

In this study,we investigated whether two brain regions,the bed nucleus of the stria terminalis(BNST)and the basolateral amygdala(BLA),affected male rats(Rattus norvigicus)ability to innately discriminate between a predator odor(cat urine)and female rat ***,a GABAa receptor agonist,was bilaterally microinjected into either the BNST or BLA of rats through

关键词： stria nucleus urine innate discriminate predator implanted Rattus nuclei agonist

Abnormal augmentation of the receptor potential and morphology changes of guinea pig's cochlea induced by Cisplatin

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Chinese Journal of Acoustics 2000年第1期19卷 1-9页

作者： LI Xingqi SUN Wei SUN Jianhe YU Ning JIANG Sichang (Institute of Otolaryngology, General Hospital of PLA Beijing 100853) Institute of Otolaryngology General Hospital of PLA Beijing100853

To investigate the characteristics of cochlear microphonic (CM), summating potential (SP) and compound action potential (CAP) and morphology changes of outer hair cells (OHCs) and inner hair cells (IHCs) after OHCs were selectively damaged by acute cochlear perfusion of cisplatin. Dynamic changes of CM, SP and CAP were recorded from the scala media of the third turn of the guinea pig's cochlea during Cisplatin perfusion into the whole cochlea for 2 hours. The results indicated that after one hour of the perfusion, the amplitude of CM, SP and CAP decreased at stimulus intensity 70 dB SPL, as compared to those examined before perfusion of Cisplatin (the average of CM increased by 3.6 mV at 90 dB SPL, average of SP increased by 1.6 mV at 120 dB SPL, average of CAP increased by 0.23 mV at 90dB SPL). After two hours of perfusion, the amplitude of CM, SP and CAP decreased in all stimulus intensities. The staining of Succinic Dehydrogenase (SDH) was weak in OHCs, while the stain ing of IHCs remained normal. transmission electron microscopic examination of organ of Corti showed varieties of morphological changes in OHCs, such as nucleus chromosome disappear, mitochondria denaturalization and number reduction, while the structure of IHC appeared normal. SDH staining showed normal staining pattern in both IHCs and OHCs when the cochlea was perfused with artificial perilymph for 2 hours. The abnormal augmentation phenomenon of CM and SP may be induced by the abnormal control of Ca++ in IHCs and OHCs. The abnormal augmentation of CAP suggests that the suppression effects of OHCs and efferent neurotransmitter on IHCs and afferent neurotransmitter may be reduced after OHCs damaged.

关键词： Cisplatin guinea augmentation perfusion cisplatin auditory cochlear evoked stria appeared

NEUROLOGICAL DISORDER

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China Medical Abstracts(Internal Medicine) 1996年第4期13卷 233-235页

TWO NEW SPECIES OF JEMBRANA DISTANT FROM CHINA(Homoptera:Aphrophoridae)

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昆虫分类学报 1986年第Z1期 131-132页

作者： Liang Aiping(Northwestern Agricultural University)

In this paper, Jembrana longipensis sp. n. from Cona, Xizang(Tibet) andJembrana taibaishanensis sp. n. from Mt. Taibai, Shaanxi are described andillustrated. The types of the new species are deposited in the Insect C... 详细信息

关键词： Homoptera Tibet stria 幼成 slender 初日 yellow shallow vertex 七公

ERG CHARACTERISTICS OF CONGENITAL STATIONARY NIGHT BLINDNESS

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Eye Science 1990年第Z1期15卷 32-35页

作者： De-zheng Wu Xijing Xu Lezheng Wu Taiqing Luo Zhongshan Ophthalmic Center Sun Yat—sen University of Medied Sciences Guangzhou China

The ERGs of 9 cases (18 eyes) of congenital stationary night blindness with normal fundi or myopia were tested. All eyes showed nonrecordable rod ERG and cone ERG with normal a-wave. Scotopic mixed ERGs were of the negative type in 7 eyes and of the ssubnormat type in 11 eyes. The b/a ratio was reduced in all eyes. The ERG characteristics are useful for the classification, estimation of the probable location of the lesion, and differential diagnosis of the disease.

关键词： congenital fundus stationary night stria probable retina inherited diffuse maximal

Expression Patterns and Implications of LaminBl in Rat Cochleae

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Current Medical Science 2019年第2期39卷 305-309页

作者： Zhi-hui DU Jin CHEN Qing-guo CHEN Liang-qiang ZHOU Dan BING Yun LIU Yan-bo SUN Peng-jun LI Fan QI Hong-mei ZHU Han-qi CHU Department of Otolaryngology-Head and Neck Surgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

LaminB1,a major component of the nuclear lamina,is a potent regulator of cellular proliferation and senescence and also known to be essential for neuronal migration and brain ***,the expression patterns of LaminB1 in the rat cochleae are still not fully *** *** blotting,and quantitative real-time PCR,we identified the distribution and expression of LaminB1 in the rat *** staining indicated that LaminBl was mainly localized in the auditory hair cells(HCs),spiral ganglion cells(SGC),stria vascularis(STV,including spiral ligament),Reissner's membrane(RM),and limbus laminae spiralis(LLS).Western blotting analysis illustrated that the distribution of LaminBl in rat cochleae was characterized by tissue *** LaminB1 protein was expressed more in SGC and basilar membrane(BM)than in ***,the mRNA expression of LaminB1 displayed difference in cochlear *** observations preliminarily revealed the expression patterns of LaminB1,providing a theoretical basis for further study on the role of LaminB1 in auditory function.

关键词： LaminB1 cochleae rat hair cell spiral ganglion cell stria vascularis

Abnormal expression of connexin 36 plays a role in the pathogenesis of levodopa induced dyskinesia in rat model of Parkinson's disease

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China Medical Abstracts(Internal Medicine) 2014年第3期31卷 193-193页

作者：高冕 Dept Neurol 1st Affil HospAnhui Med Univ

Objective To expore whether gap junction disturbances are involved in the pathogenesis of levodopa-induced dyskinesia(LID).Methods The hemi-parkinsonian(PD)rat was treated intraperitoneally with L-dopa methylester(20 mg/kg)and benserazid(10 mg/kg)for21 days and abnormal involuntary movement was evaluated to establish LID rat *** experimental animals were divided into three groups:LID group,PD

关键词： pathogenesis connexin junction abnormal stria cortex labeling specifically staining elevated