检索结果-南通市图书馆

Dental Plaque streptococci and Their Amoxicillin Resistance in Children with Congenital Heart Anomalies: Results of a Prospective Study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Stomatology 2014年第7期4卷 345-351页

作者： Aida Rexhepi Raimonda Niko Agim Begzati Mergime Prekazi Loxha Vjosa Krasniqi Zana Agani Blerta Xhemajli Teuta Kutllovci Urata Tahiri Department of Maxillofacial Surgery Clinical University Center of Kosova Prishtina Kosova Department of Oral Surgery Clinical University Center of Kosova Prishtina Kosova Department of Pediatric Dentistry Clinical University Center of Kosova Prishtina Kosova Pediatric Clinic Faculty of Medicine University of Tirana Tirana Albania

Children with congenital heart diseases (CHD) are considered to be at higher risk of development of a Bacterial Endocarditic (BE) from infectious diseases of the oral cavity and following dental treatments. They represent the largest group of patients with special medical needs who appear in the daily dental practice. Maintenance of oral health and oral hygiene is suitable to reduce the incidence of bacteremia. Oral hygiene is more important in reducing the risk of BE than the administration of antibiotic-prophylaxis before dental procedures. The purpose of this study was to identify the strains of streptococci viridians group from dental plaque and their amoxicillin resistance at children with congenital heart disease. The study was carried out in University Dentistry Clinical Center of Kosova, Department of Pediatric Dentistry in cooperation with the Micro-biologic Department. Participants in this study (n = 90) were children between 6 - 15 years old, divided in the control group of healthy children (n = 30), and two study groups, first group, children with CHD who have not taken antibiotics within last three months (n = 30) and second group, children with CHD who have taken antibiotics within three months (n = 30). The gram positive cocci were identified using the automated system, VITEK 2 (BioMerux), while for determining amoxicillin resistance cocci the disc diffusion method was used. By analyzing the three groups of children regarding isolated dental plaque streptococci, in general the Viridans group of streptococci (VGS) has dominated our results, with a higher percentage of streptococcus Mitis group (37.2%). The highest resistance of VGS against amoxicilin was in the group of children with CHD, which have been using antibiotics within 3 months (23.3%). In the other two groups the resistance against amoxicillin was found in a lower percentage (3.3%). Based on the results of our study we can conclude that frequent use of amoxicillin may result in an increasing

关键词： Congenital Heart Anomalies Bacterial Endocarditis Dental Bacterial Plaque Bakteremia streptococci Antibiotics

The prevalence of virulent clonal strains of mutans streptococci in vivo and co-culture succession of the strains in vitro—Virulence potential of mutans streptococci

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Stomatology 2011年第2期1卷 18-24页

作者： Mingyu Li Guang-yun Lai Jun Wang 不详

Purpose:To examine selected putative virulent prop-erties of mutans streptococci in two groups with dif-ferent caries activity and to examine co-culture hy-bridization of the strains in vitro. Methods: A set of strains from caries-free subjects (115) and another set from caries-active subjects (165) were isolated. Each strain was characterized for three virulence determi-nants. The clinical bacteria were then cocultured by three strains exhibiting the highest levels of virulence. Isolate colonies of last filial generation bacteria were enrichment-incubated and estimated for virulence again. RAPD-PCR and MLEE analyses were processed for parental bacteria and last filial genera-tion one. Results: No difference associated with caries activity of the subjects from whom the isolates origi-nated. Virulent properties of a filial generation strains was not different in the same generation, but was very different from their parent strains. Conclu-sion: The coexist properties of virulent polyclonal strain of MS may hold in a very general conditional sense in a dental plaque ecosystem in vivo, however, one of the co-culture strains may became dominant and displa- ced the others as the result of continuous ecological succession in vitro.

关键词： Ecological Phenomenon Mutans streptococci Co-Culture Virulent in Vitro

Molecular dissection of phage lysin PlySs2: integrity of the catalytic and cell wall binding domains is essential for its broad lytic activity

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Virologica Sinica 2015年第1期30卷 45-51页

作者： Yanling Huang Hang Yang Junping Yu Hongping Wei Key Laboratory of Special Pathogens and Biosafety Center for Emerging Infectious Diseases Wuhan Institute of Virology Chinese Academy of Sciences

The novel phage lysin PlySs2, is reported to be highly active against various bacteria, including staphylococci, streptococci and Listeria. However, the molecular mechanisms underlying its broad lytic spectrum remain to be established. In the present study, the lytic activity of the catalytic domain(CD, PlySc) and binding specificity of the cell wall binding domain(CBD, PlySb) of PlySs2 were examined. Our results showed that PlySc alone maintains very limited lytic activity. Enhanced green fluorescent protein(EGFP)-fused PlySb displayed high binding affinity to the streptococcal strains tested, including ***, ***, and ***, but not staphylococci, supporting its utility as a good CBD donor for streptococcal-targeted lysin engineering. EGFP-fused intact PlySs2 similarly displayed high affinity for streptococci, but not staphylococci. Notably, four truncated PlySb fragments showed no binding capacity. These findings collectively indicate that integrity of the PlySc and PlySb domains is an essential determinant of the broad lytic activity of PlySs2.

关键词： streptococci lysin cell wall binding domain catalytic domain bacterial resistance

Severe monobacterial necrotizing soft tissue infection by group A Streptococcus:A surgical emergency

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Biomedicine 2012年第3期2卷 250-252页

作者： Sophocles Lanitis Khan MAA Sgourakis G Kontovounisios C Papaconstandinou T Karaliotas C Second Surgical Department and Unit of Surgical Oncology "Korgialenio-Benakio" Red Cross Athens General Hospital Specialist Registrar Department of Plastic and Reconstructive SurgeryCastle Hill Hospital

Eight percent of necrotizing soft tissue infections(NSTI) are attributable to group A streptococci(GAS),and among these,50%develop streptococcal toxic shock *** reported mortality associated with NSTI reaches 32%.We present cases of two healthy individuals with minor GAS skin infection which developed to a rapidly progressed NSTI and sepsis despite of the antibiotic treatment,aiming to discuss the lessons learned from the course and management of these patients.

关键词： Necrotizing soft tissue infection Group A streptococci Fulminant skin necrosis

Perianal infectious dermatitis: An underdiagnosed, unremitting and stubborn condition

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Pediatrics 2018年第4期7卷 89-104页

作者： Elena Daniela Serban 2nd Department of Pediatrics "Iuliu Hatieganu" University of Medicine and Pharmacy Emergency Hospital for Children

Perianal infectious dermatitis(PID) represents a super-ficial inflammation of the perianal skin, which is of bac-terial origin(classically, group A beta-hemolytic strepto-cocci). This narrative review aims to critically review and summarize the available scientific literature regarding pediatric PID, being the first of its kind, to the best of the author's knowledge. It also reports the first cases of Romanian children with PID. Multiple databases were subjected to systematic literature search(from 1966 to April 30, 2018) to identify studies and case reports of children with PID. As such, this review provides up-dated information about essential aspects of PID(epi-demiology, etiology, pathogenesis, as well as clinical features, required investigations and therapeutic options) and of diagnostic pitfalls. Although a well-defined entity, PID remains largely underdiagnosed. PID may mimic other common conditions with skin manifestations(like candidiasis, pinworms, eczema, irritant dermatitis, anal fissure, hemorrhoids, Crohn's disease, psoriasis, sebor-rheic dermatitis, zinc deficiency dermatosis and even sexual abuse), with consequent unnecessary, sometimes expensive and invasive investigations and futile therapies, which cause patients and families discomfort and distress. Since PID has an unremitting course, early recognition is imperative, as it allows for prompt and efficacious antibiotic therapy. However, PID represents a stubborn condition and, even if properly treated, its recurrence rate remains high. Further well-designed prospective randomized controlled trials, with adequate follow-up, are required in order to formulate the optimum personalized antibiotic therapy(oral alone or in association with topical medication), able to prevent recurrences. Awareness of this condition by healthcare professionals should improve patient outcomes.

关键词： Perianal dermatitis Perianal streptococcal dermatitis Beta-hemolytic streptococci Staphylococcus aureus Perineal streptococcal dermatitis Perianal swab culture Differential diagnosis Antibiotic therapy Perianal streptococcal disease

学龄前儿童乳牙釉质发育缺陷对口腔中变形链球菌水平的影响

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

广东牙病防治 1996年第S1期4卷 6-8页

作者：荣文笙杨圣辉卞金有杨是北京医科大学口腔医学院 100081

自从Clarke首先从人类龋齿中分离出变形链球菌到目前,已公认变形链球菌是引起龋齿发生的最主要的细菌。变形链球菌具有粘附和聚集的能力,尽管它粘附、聚集的机制尚不完全清楚,但口腔中的某些因素可以影响变形链球菌的殖居。本研究采用... 详细信息

自从Clarke首先从人类龋齿中分离出变形链球菌到目前,已公认变形链球菌是引起龋齿发生的最主要的细菌。变形链球菌具有粘附和聚集的能力,尽管它粘附、聚集的机制尚不完全清楚,但口腔中的某些因素可以影响变形链球菌的殖居。本研究采用病例对照的方法,比较有无釉质发育缺陷的儿童口腔中变形链球菌的水平,探讨釉质发育缺陷对口腔中变形链球菌殖居的影响。

关键词：变形链球菌釉质发育缺陷学龄前儿童牙釉质 streptococci 口腔卫生状况龋齿口腔医学 dental mutans