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Antimicrobial activities of the tissue extracts of Babylonia spirata Linnaeus,1758 (Mollusca:Gastropoda) from Thazhanguda,southeast coast of India

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Asian Pacific Journal of Tropical Biomedicine 2012年第1期2卷 36-40页

作者： Periyasamy N Srinivasan M Balakrishnan S Centre of Advanced Study in Marine Biology Faculty of Marine SciencesAnnamalai University

Objective:To investigate the antimicrobial activity of the tissue extracts of Babylonia spirata(***)against nine bacterial and three fungal ***:Crude extract of gastropod was tested for inhibition of bacterial and fungal *** assay was carried out by disc diffusion method and in vitro antifungal activity was determined against Czapex Dox *** antimicrobial activity was measured accordingly based on the inhibition zone around the disc impregnated with gastropod *** size of muscle protein was determined using sodium dodecyl sulfate polyacrylamide gel electrophoresis(SDS-PAGE).And fourier transform infrared spectroscopy(FT1R)spectro photometry analysis was also ***:The maximum inhibition zone(12 mm)was observed against Pseudomonas aeruginosa in the crude ethanol extract of *** and the minimum inhibition zone(2 mm)was noticed against Staphylococcus aureus in the crude methanol extract of *** extract of *** showed the highest activity against Vibrio parahaemolyticus,Staphylococcus aureus and Candida ***,acetone,methanol,chloroform and water extracts showed antimicrobial activity against almost all the bacteria and *** with water extracts,ethanol and methanol extracts showed higher activity against all *** molecular weight of protein of the gastropod sample ranged from 2-110 kDa on *** analysis revealed the presence of bioactive compounds signals at different ***:The research shows that the great medicinal value of the gastropod muscle of *** may be due to high quality of antimicrobial compounds.

关键词： Gastropod Babylonia spirata Antimicrobial activity SDS-PAGE FTIR Antibacterial activity Antifungal activity Inhibition zone Muscle protein Bioactive compound

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