检索结果-南通市图书馆

Drug-eluting stent for the treatment of small coronary lesion:comparison between sirolimus- and paclitaxel-eluting stent

引用

Chinese Medical Journal 2007年第7期120卷 569-573页

作者： LI Jian-jun XU Bo YANG Yue-Jin CHEN Ji-lin QIAO Shu-bin MA Wei-hua QIN Xue-wen YAO Min LIU Hai-bo WU Yong-jian YUAN Jin-qing CHEN Jue YOU Shi-jie DAI Jun XIA Ran GAO Run-lin Department of Cardiology Fuwai Hospital Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100037 China

Background Patients with small coronary lesions are at increased risk for repeat interventions after coronary angioplasty and stenting. The efficacy of drug-eluting stents （DES） has been demonstrated to improve the outcomes of these patients and is a focus of interest. Currently, two platforms of DES are available （sirolimus-eluting stent （SES） and paclitaxel-eluting stent （PES））. However, it has less been known that DES, SES vs PES, is superior for the treatment of small coronary lesions. Methods In this retrospective study, 87 consecutive patients with 151 lesions underwent implantation of coronary SES （n=68） and PES （n=83）. Quantitative coronary angiography （QCA） was performed at the time of stent implantation and subsequently at 8 months post-stenting. small vessel disease was defined as lesions in vessels with diameter 42.5 mm measured by QCA. Major adverse cardiac events （MACE） including death, thrombosis, nonfatal myocardial infarction and target lesion revascularization （TLR） were compared between the two groups. Results Baseline clinical characteristics and angiographic parameters were similar between the two groups. At clinical and angiographic follow-up, overall thrombosis rates were similar in both groups （0 vs 1.2%, P〉0.05）. The TLR and in-segment restenosis were not significantly different （19.1% vs 25.3%; 10.3% vs 10.8%, P=0.365 and P=0.913 respectively） between the two groups. The in-stent restenosis rate, however, was significantly higher in the PES group （4.4% vs 21.7%; P=0.002）. Similarly, the late loss was significantly higher in the PES group （（0.14±0.38） mm vs （0.49±0.61） mm; P〈0.001）. Conclusions In this small sample-size, non-randomized study, the data indicated that implantation of SES for the treatment of patients with small coronary lesion showed more favorable results in respect of restenosis compared with PES implantation.

关键词： drug-eluting stent coronary artery disease angiography restenosis small coronary lesion

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：